Markers and risk factors for chronic kidney disease in sub-Saharan Africans: baseline levels and 12-month trajectories in newly referred patients in Cameroon.

abstract：BACKGROUND:Complement activation plays a substantial role in the pathogenesis of primary membranous nephropathy (pMN). C5b-9, C3c, MBL, and factor B have been documented in the subepithelial immune deposits. However, the changing of complement activation products in circulation and urine is not clear. METHODS:We measu...

journal_title：BMC nephrology

authors： Zhang MF,Huang J,Zhang YM,Qu Z,Wang X,Wang F,Meng LQ,Cheng XY,Cui Z,Liu G,Zhao MH

更新日期：2019-08-09 00:00:00

abstract：BACKGROUND:This is the first study that has examined non-cardiac incidental findings in research cardiac computed tomography (CT) of hemodialysis patients and their relationship with patient characteristics. METHODS:We performed a cross-sectional analysis in the Predictors of Arrhythmic and Cardiovascular Events in En...

journal_title：BMC nephrology

authors： Jaar BG,Zhang L,Chembrovich SV,Sozio SM,Shafi T,Scialla JJ,Tomaselli GF,Lima JA,Kao WH,Parekh RS,Meoni LA

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Protein-bound uremic toxins are associated with poor outcomes in patients with chronic kidney disease. The aim of this study is to investigate the relationship between indoxyl sulfate (IS), a protein-bound solute, and 90-day mortality in patients with acute kidney injury. METHODS:Adults with hospital-acquir...

journal_title：BMC nephrology

authors： Wang W,Hao G,Pan Y,Ma S,Yang T,Shi P,Zhu Q,Xie Y,Ma S,Zhang Q,Ruan H,Ding F

更新日期：2019-02-14 00:00:00

abstract：BACKGROUND:It remained lack of a kind of contrast-induced acute kidney injury (CI-AKI) model which was widely used in clinical practice and comparable to CI-AKI in humans. METHODS:Fifty Sprague-Dawley rats were divided into five groups of 10 rats each: (1) sham group (normal saline [NS] + NS); (2) NS plus low osmolali...

journal_title：BMC nephrology

authors： Liu YH,Xue JH,Wu DX,Bei WJ,Wang K,Liu Y,Chen JY,Tan N

更新日期：2019-07-04 00:00:00

abstract：BACKGROUND:Anabolic-androgenic steroids and growth hormone are among the most commonly used supplements by sportsmen and sportswomen. The aim of this systematic review is to collect and report available data about renal safety of anabolic-androgenic steroids and growth hormone (GH). METHODS:The search strategy was in ...

journal_title：BMC nephrology

authors： Davani-Davari D,Karimzadeh I,Khalili H

更新日期：2019-05-31 00:00:00

abstract：BACKGROUND:Cardiovascular disease is the most common complication and leading cause of death in maintenance hemodialysis patients. The protection mechanism of hydrogen sulfide (H2S) and the specific role of conventional protein kinase C βII (cPKCβII)/Akt signaling pathway in the formation of atherosclerosis is still co...

journal_title：BMC nephrology

authors： Xiong R,Lu X,Song J,Li H,Wang S

更新日期：2019-09-14 00:00:00

abstract：BACKGROUND:Single nucleotide polymorphisms (SNPs) are the most common forms of sequence variations in the human genome. They contribute to the human phenotypic spectrum and are associated with variations in response to pathogens, drugs and vaccines. Recently, SNPs in three human genes involved in kidney development (RE...

journal_title：BMC nephrology

authors： Raghavendra A,Siji A,Sridhar TS,Phadke K,Vasudevan A

更新日期：2011-10-28 00:00:00

abstract：BACKGROUND:Calcific Uremic Arteriolopathy (CUA) is a rare disease, causing painful skin ulcers in patients with end stage renal disease. Recommendations for CUA management and treatment are lacking. METHODS:We conducted a retrospective cohort study on CUA cases identified in western France, in order to describe its ma...

journal_title：BMC nephrology

authors： Gaisne R,Péré M,Menoyo V,Hourmant M,Larmet-Burgeot D

更新日期：2020-02-26 00:00:00

abstract：BACKGROUND:Acute kidney injury (AKI) places a heavy burden on the healthcare system in China and is usually misdiagnosed. However, there are limited studies that have described the epidemiology and diagnosis of AKI in China. The aim of this study was to describe the incidence and diagnosis of AKI in hospitalized adult ...

journal_title：BMC nephrology

authors： Cheng X,Wu B,Liu Y,Mao H,Xing C

更新日期：2017-06-24 00:00:00

abstract：BACKGROUND:Inherited cystic kidney disease is a spectrum of disorders in which clusters of renal cysts develop as the result of genetic mutation. The exact methods and pipelines for defining genetic mutations of inherited cystic kidney disease are not clear at this point. This 3-year, prospective, multicenter, cohort s...

journal_title：BMC nephrology

authors： Park HC,Ryu H,Kim YC,Ahn C,Lee KB,Kim YH,Kim Y,Han S,Kim Y,Bae EH,Ma SK,Kang HG,Ahn YH,Park E,Jeong K,Lee J,Choi J,Oh KH,Oh YK

更新日期：2021-01-06 00:00:00

abstract：BACKGROUND:The burden of kidney diseases is reported to be higher in lower- and middle-income countries as compared to developed countries, and countries in sub-Saharan Africa are reported to be most affected. Health systems in most sub-Sahara African countries have limited capacity in the form of trained and skilled h...

journal_title：BMC nephrology

authors： Furia FF,Shoo J,Ruggajo PJ,Kilonzo K,Basu G,Yeates K,Varughese S,Svarstad E,Kisanga O

更新日期：2019-10-17 00:00:00

abstract：BACKGROUND:Kidney injury molecule-1 (KIM-1) is a biomarker useful for detecting early tubular damage and has been recently reported as a useful marker for evaluating kidney injury in IgA nephropathy (IgAN). We therefore investigated whether treatment decreases urinary KIM-1 excretion in IgAN. METHODS:We prospectively ...

journal_title：BMC nephrology

authors： Seo MS,Park MY,Choi SJ,Jeon JS,Noh H,Kim JK,Han DC,Hwang SD,Jin SY,Kwon SH

更新日期：2013-07-09 00:00:00

abstract：BACKGROUND:Aluminium (Al) toxicity was frequent in the 1980s in patients ingesting Al containing phosphate binders (Alucaps) whilst having HD using water potentially contaminated with Al. The aim of this study was to determine the risk of Al toxicity in HD patients receiving Alucaps but never exposed to contaminated di...

journal_title：BMC nephrology

authors： Pepper R,Campbell N,Yaqoob MM,Roberts NB,Fan SL

更新日期：2011-10-12 00:00:00

abstract：BACKGROUND:People with end stage renal disease (ESRD) face important health-related decisions concerning end-of-life care and the use of life-support technologies. While people often want to be involved in making decisions about their health, there are many challenges. People with advanced illness may have limited or w...

journal_title：BMC nephrology

authors： Kapell Brown C,Kryworuchko J,Martin W

更新日期：2018-09-12 00:00:00

abstract：BACKGROUND:Increased leucine-rich α2-glycoprotein-1 (LRG1) has been observed in various inflammatory and autoimmune diseases. We aimed to explore the expression and role of LRG1 in lupus nephritis (LN). METHODS:Plasma LRG1 (pLRG1) was measured by enzyme-linked immunosorbent assay in 101 patients with renal biopsy-prov...

journal_title：BMC nephrology

authors： Yang Y,Luo R,Cheng Y,Liu T,Dai W,Li Y,Ge S,Xu G

更新日期：2020-04-06 00:00:00

abstract：BACKGROUND:Urinary albumin can be measured in 24 h or spot samples. The 24 h urinary albumin excretion rate is considered the gold standard, but is cumbersome to collect. Instead, often an overnight sample is collected, and adjusted for dilution. Proxies for 24 h excretion rate have been studied in diabetics, but seldo...

journal_title：BMC nephrology

authors： Fagerstrom P,Sallsten G,Akerstrom M,Haraldsson B,Barregard L

更新日期：2015-01-24 00:00:00

abstract：BACKGROUND:Autosomal dominant polycystic kidney disease (ADPKD) is a hereditary disease characterized by the presence of renal cysts. Over time the expanding cysts lead to progressive renal failure. The use of tolvaptan, a V2-receptor antagonist, was recently approved in ADPKD patients. It was demonstrated that tolvapt...

journal_title：BMC nephrology

authors： Pellegrino AM,Annicchiarico Petruzzelli L,Riccio E,Pisani A

更新日期：2019-11-21 00:00:00

abstract：BACKGROUND:Primary hyperoxaluria type 1 is a rare autosomal recessive disease of glyoxylate metabolism caused by a defect in the liver-specific peroxisomal enzyme alanine:glyoxylate aminotransferase (AGT) that leads to hyperoxaluria, recurrent urolithiasis, and nephrocalcinosis. METHODS:Two unrelated patients with rec...

journal_title：BMC nephrology

authors： Li GM,Xu H,Shen Q,Gong YN,Fang XY,Sun L,Liu HM,An Y

更新日期：2014-06-17 00:00:00

abstract：BACKGROUND:Evidence suggests that exercise training for hemodialysis patients positively improves morbidity and mortality outcomes, yet exercise programs remain rare and are not systematically incorporated into care. We developed a research-based film, Fit for Dialysis, designed to introduce, motivate, and sustain exer...

journal_title：BMC nephrology

authors： Kontos P,Alibhai SM,Miller KL,Brooks D,Colobong R,Parsons T,Jassal SV,Thomas A,Binns M,Naglie G

更新日期：2017-01-26 00:00:00

abstract：BACKGROUND:Lower serum bicarbonate, mainly due to the modern Western-style diet, and renal hyperfiltration (RHF) are both independently associated with higher mortality in the general population with preserved renal function. The objective of this study was to evaluate the association between serum bicarbonate and RHF....

journal_title：BMC nephrology

authors： Park M,So R,Joo KW,Yoon HJ

更新日期：2016-01-06 00:00:00

abstract：BACKGROUND:Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in patients with chronic kidney disease (CKD). Cardiovascular risk assessment in this population is hampered by the failure of traditional risk factors to fully account for the elevated CVD risk (reverse epidemiology effect) and the...

journal_title：BMC nephrology

authors： Junyent M,Martínez M,Borràs M,Coll B,Valdivielso JM,Vidal T,Sarró F,Roig J,Craver L,Fernández E

更新日期：2010-07-07 00:00:00

abstract：BACKGROUND:Hypertension is a public health problem with mostly unknown causes, and where strong hereditary genetic alterations have not been fully elucidated. However, the use of experimental models has provided valuable information. Recent evidences suggest that alterations in key nephrogenic factors, such as Wilms' t...

journal_title：BMC nephrology

authors： Mazzei L,García M,Calvo JP,Casarotto M,Fornés M,Abud MA,Cuello-Carrión D,Ferder L,Manucha W

更新日期：2016-03-24 00:00:00

abstract：BACKGROUND:Acute kidney injury (AKI) remains a frequent complication in children undergoing hematopoietic stem cell transplantation (HSCT) and an independent risk factor of the patient's survival and a prognostic factor of progression to chronic kidney disease (CKD). However, the causes of these complications are diver...

journal_title：BMC nephrology

authors： Hirano D,Kakegawa D,Miwa S,Umeda C,Takemasa Y,Tokunaga A,Kawakami Y,Ito A

更新日期：2020-08-27 00:00:00

abstract：BACKGROUND:Heavy metal poisoning can cause debilitating illness if left untreated, and its management in anuric patients poses challenges. Literature with which to guide clinical practice in this area is rather scattered. CASE PRESENTATION:We present a case of symptomatic lead and arsenic poisoning from use of Ayurved...

journal_title：BMC nephrology

authors： Hsiao CY,Gresham C,Marshall MR

更新日期：2019-10-17 00:00:00

abstract：BACKGROUND:Serum p-cresyl sulfate (PCS) associates with cardiovascular disease in patients with chronic kidney disease. PCS concentrations are determined by intestinal uptake of p-cresol, human metabolism to PCS and renal clearance. Whether intestinal uptake of p-cresol itself is directly associated with cardiovascular...

journal_title：BMC nephrology

authors： Poesen R,Viaene L,Verbeke K,Augustijns P,Bammens B,Claes K,Kuypers D,Evenepoel P,Meijers B

更新日期：2014-06-09 00:00:00

abstract：BACKGROUND:Abdominal aortic calcification assessed by X-ray is recommended to evaluate vascular calcification in dialysis patients. It has been shown that abdominal aortic calcification score (AACS) is a predictor of adverse outcomes in hemodialysis patients, but evidence regarding its prognostic value in peritoneal di...

journal_title：BMC nephrology

authors： Ma D,Yan H,Yang X,Yu Z,Ni Z,Fang W

更新日期：2020-04-30 00:00:00

abstract：BACKGROUND:Acute kidney injury (AKI) is a common clinical problem. Studies have documented the incidence of AKI in a variety of populations but to date we do not believe the real incidence of AKI has been accurately documented in a district general hospital setting.The aim here was to describe the detected incidence of...

journal_title：BMC nephrology

authors： Bedford M,Stevens PE,Wheeler TW,Farmer CK

更新日期：2014-06-21 00:00:00

abstract：BACKGROUND:About 1% of patients admitted to the Emergency Department (ED) have hypernatremia, a condition associated with a mortality rate of 20 to 60%. Management recommendations originate from intensive care unit studies, in which patients and medical diseases differ from those in ED. METHODS:We retrospectively stud...

journal_title：BMC nephrology

authors： Bataille S,Baralla C,Torro D,Buffat C,Berland Y,Alazia M,Loundou A,Michelet P,Vacher-Coponat H

更新日期：2014-02-21 00:00:00

abstract：BACKGROUND:The use of the Internet for searching and sharing health information and for health care interactions may have a great potential for Renal Transplant Recipients (RTR). This study aims to determine the characteristics associated with Internet and social network use in a representative sample of RTR at the tim...

journal_title：BMC nephrology

authors： Mouelhi Y,Alessandrini M,Pauly V,Dussol B,Gentile S

更新日期：2017-08-03 00:00:00

abstract：BACKGROUND:Major Depressive Disorder (MDD) can lead to adverse cardiovascular outcomes in patients with chronic kidney disease (CKD). Although one of the proposed mechanisms is heightened platelet activation, effects of MDD and its treatment with a selective serotonin reuptake inhibitor (SSRI) on platelet function in p...

journal_title：BMC nephrology

authors： Jain N,Wan F,Kothari M,Adelodun A,Ware J,Sarode R,Hedayati SS

更新日期：2019-10-29 00:00:00