Hyperphosphatemia and risks of acute kidney injury, end-stage renal disease, and mortality in hospitalized patients.

abstract：BACKGROUND:Autosomal dominant polycystic kidney disease (ADPKD) is one of the most common hereditary kidney diseases that frequently result in renal failure. In this cross-sectional observational cohort study, we evaluated urinary angiotensinogen (AGT) as a potential biomarker to assess renal function in ADPKD. METHOD...

journal_title：BMC nephrology

authors： Park HC,Kang AY,Jang JY,Kim H,Han M,Oh KH,Kim SH,Noh JW,Cheong HI,Hwang YH,Ahn C

更新日期：2015-06-20 00:00:00

abstract：BACKGROUND:Accumulating evidence suggests that a decrease in brain-derived neurotrophic factor (BDNF) level induces a variety of psychiatric and neurological disorders. However, the expression and role of BDNF in the kidney have not been explored. The present study examined the expression of BDNF and tropomyosin-relate...

journal_title：BMC nephrology

authors： Tao YS,Piao SG,Jin YS,Jin JZ,Zheng HL,Zhao HY,Lim SW,Yang CW,Li C

更新日期：2018-03-14 00:00:00

abstract：BACKGROUND:To date, limited research has been dedicated to exploring the experience of decision-making for chronic kidney disease (CKD) patients who have initiated dialysis and have to make decisions in the context of managing multiple illnesses. Evidence about the experience of decision-making for minority or disadvan...

journal_title：BMC nephrology

authors： Muscat DM,Kanagaratnam R,Shepherd HL,Sud K,McCaffery K,Webster A

更新日期：2018-11-27 00:00:00

abstract：BACKGROUND:The Canadian Study of Prediction of Death, Dialysis and Interim Cardiovascular Events (CanPREDDICT) is a large, prospective, pan-Canadian, cohort study designed to improve our understanding of determinants of renal and cardiovascular (CV) disease progression in patients with chronic kidney disease (CKD). The...

journal_title：BMC nephrology

authors： Levin A,Rigatto C,Brendan B,Madore F,Muirhead N,Holmes D,Clase CM,Tang M,Djurdjev O,CanPREDDICT investigators.

更新日期：2013-06-11 00:00:00

abstract：BACKGROUND:Primary nephrotic syndrome (PNS) is a common glomerular disease in children. T cell dysfunction plays a crucial role in the pathogenesis of PNS. Moreover, dysbiosis of gut microbiota contributes to immunological disorders. Whether the initial therapy of PNS affects gut microbiota remains an important questio...

journal_title：BMC nephrology

authors： Kang Y,Feng D,Law HK,Qu W,Wu Y,Zhu GH,Huang WY

更新日期：2019-11-26 00:00:00

abstract：BACKGROUND:Patients with end-stage renal disease (ESRD) exhibit a premature aging phenotype of immune system, which is recently concerned as a significant factor for increased risk of various morbidities. Nevertheless, there are few dates explicating the relevancy of T cell senescence to mortality. In this study, we pr...

journal_title：BMC nephrology

authors： Xiang F,Chen R,Cao X,Shen B,Chen X,Ding X,Zou J

更新日期：2020-07-13 00:00:00

abstract：BACKGROUND:Use of serum creatinine to estimate GFR may lead to underestimation of the association between self-reported frailty and kidney function. Our objectives were to evaluate the association of measured GFR (mGFR) with self-reported frailty among patients with CKD and to determine whether self-reported frailty wa...

journal_title：BMC nephrology

authors： Delgado C,Grimes BA,Glidden DV,Shlipak M,Sarnak MJ,Johansen KL

更新日期：2015-12-09 00:00:00

abstract：BACKGROUND:Chronic kidney disease (CKD) is increasingly being recognized as a predictor for both end-stage renal disease and cardiovascular disease. The present study, conducted on individuals from a community in Arita, Japan, was designed to evaluate biomarkers that can be used to determine the associated factors for ...

journal_title：BMC nephrology

authors： Takamatsu N,Abe H,Tominaga T,Nakahara K,Ito Y,Okumoto Y,Kim J,Kitakaze M,Doi T

更新日期：2009-10-27 00:00:00

abstract：BACKGROUND:There is a lack of online, evidence-based information and resources to support home-based care of childhood CKD stages 3-5. METHODS:Qualitative interviews were undertaken with parents, patients and professionals to explore their views on content of the proposed online parent information and support (OPIS) w...

journal_title：BMC nephrology

authors： Swallow VM,Hall AG,Carolan I,Santacroce S,Webb NJ,Smith T,Hanif N

更新日期：2014-02-18 00:00:00

abstract：BACKGROUND:Accurate estimation of glomerular filtration rate (GFR) is important for diagnosis and risk stratification in chronic kidney disease and for selection of living donors. Ethnic differences have required correction factors in the originally developed creatinine-based GFR estimation equations for populations ar...

journal_title：BMC nephrology

authors： Kumar V,Yadav AK,Yasuda Y,Horio M,Kumar V,Sahni N,Gupta KL,Matsuo S,Kohli HS,Jha V

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:African Americans have an increased incidence and worse prognosis with chronic kidney disease (CKD--estimated glomerular filtration rate [eGFR] <60 ml/min/1.73 m2) than their counterparts of European-descent. Inflammation has been related to renal disease in non-Hispanic whites, but there are limited data on...

journal_title：BMC nephrology

authors： Fox ER,Benjamin EJ,Sarpong DF,Nagarajarao H,Taylor JK,Steffes MW,Salahudeen AK,Flessner MF,Akylbekova EL,Fox CS,Garrison RJ,Taylor HA Jr

更新日期：2010-01-15 00:00:00

abstract：BACKGROUND:In a recent study we demonstrated that low birth weight (LBW) was associated with increased risk of progressive IgA nephropathy (IgAN). In the present study we investigate whether this could be explained by differences in glomerular morphological parameters. METHODS:The Medical Birth Registry of Norway has ...

journal_title：BMC nephrology

authors： Ruggajo P,Leh S,Svarstad E,Marti HP,Vikse BE

更新日期：2018-10-22 00:00:00

abstract：BACKGROUND:The patterns, performance characteristics, and yield of diagnostic tests ordered for the evaluation of acute kidney injury (AKI) have not been rigorously evaluated. METHODS:We characterized the frequency of AKI diagnostic testing for urine, blood, radiology, and pathology tests in all adult inpatients who w...

journal_title：BMC nephrology

authors： Leaf DE,Srivastava A,Zeng X,McMahon GM,Croy HE,Mendu ML,Kachalia A,Waikar SS

更新日期：2016-01-15 00:00:00

abstract：BACKGROUND:Previous studies have linked smaller kidney dimensions to increased blood pressure. However, patients with Balkan Endemic Nephropathy (BEN), whose kidneys shrink during the course of the disease, do not manifest increased blood pressure. The authors evaluated the relationship between kidney cortex width, kid...

journal_title：BMC nephrology

authors： Dimitrov PS,Simeonov VA,Tsolova SD,Bonev AG,Georgieva RB,Karmaus WJ

更新日期：2006-08-23 00:00:00

abstract：BACKGROUND:S100A12 protein is an endogenous receptor ligand for advanced glycation end products. In this study, the plasma S100A12 level was assessed as an independent predictor of mortality, and its utility in clinical settings was examined. METHODS:In a previous cross-sectional study, plasma S100A12 levels were meas...

journal_title：BMC nephrology

authors： Shiotsu Y,Mori Y,Nishimura M,Hatta T,Imada N,Maki N,Iida K,Iwamoto N,Matsuoka E,Tamagaki K,Kosaki A

更新日期：2013-01-16 00:00:00

abstract：BACKGROUND:Aluminium (Al) toxicity was frequent in the 1980s in patients ingesting Al containing phosphate binders (Alucaps) whilst having HD using water potentially contaminated with Al. The aim of this study was to determine the risk of Al toxicity in HD patients receiving Alucaps but never exposed to contaminated di...

journal_title：BMC nephrology

authors： Pepper R,Campbell N,Yaqoob MM,Roberts NB,Fan SL

更新日期：2011-10-12 00:00:00

abstract：BACKGROUND:Interleukin 17 is a proinflammatory cytokine involved in immune response after allograft transplantation. IL-17 family of proinflammatory cytokines includes IL-17A and IL-17F. Previous studies have demonstrated that the rs2275913 IL17A and the rs11465553 IL17F gene polymorphism are associated with kidney all...

journal_title：BMC nephrology

authors： Domanski L,Kłoda K,Patrzyk M,Wisniewska M,Safranow K,Sienko J,Sulikowski T,Staniszewska M,Pawlik A

更新日期：2019-04-08 00:00:00

abstract：BACKGROUND:Recently there has been a progressive loss of specialty related skills for nephrologists. Among the skills we find the kidney biopsy that has a central role in diagnosis of renal parenchymal disease. One of the causes might be the belief that the kidney biopsy should be performed only in larger Centers which...

journal_title：BMC nephrology

authors： Esposito V,Mazzon G,Baiardi P,Torreggiani M,Semeraro L,Catucci D,Colucci M,Mariotto A,Grosjean F,Bovio G,Esposito C

更新日期：2018-01-15 00:00:00

abstract：BACKGROUND:Cardiovascular disease is the most common complication and leading cause of death in maintenance hemodialysis patients. The protection mechanism of hydrogen sulfide (H2S) and the specific role of conventional protein kinase C βII (cPKCβII)/Akt signaling pathway in the formation of atherosclerosis is still co...

journal_title：BMC nephrology

authors： Xiong R,Lu X,Song J,Li H,Wang S

更新日期：2019-09-14 00:00:00

abstract：BACKGROUND:Early preparation for renal replacement therapy (RRT) is recommended for patients with advanced chronic kidney disease (CKD), yet many patients initiate RRT urgently and/or are inadequately prepared. METHODS:We conducted audio-recorded, qualitative, directed telephone interviews of nephrology health care pr...

journal_title：BMC nephrology

authors： Greer RC,Ameling JM,Cavanaugh KL,Jaar BG,Grubbs V,Andrews CE,Ephraim P,Powe NR,Lewis J,Umeukeje E,Gimenez L,James S,Boulware LE

更新日期：2015-03-28 00:00:00

abstract：BACKGROUND:In patients with autosomal dominant polycystic kidney disease (ADPKD), malnutrition may develop as renal function declines and the abdominal organs become enlarged. We investigated the relationship of intra-abdominal mass with nutritional status. METHODS:This cross-sectional study was performed at a tertiar...

journal_title：BMC nephrology

authors： Ryu H,Kim H,Park HC,Kim H,Cho EJ,Lee KB,Chung W,Oh KH,Cho JY,Hwang YH,Ahn C

更新日期：2017-01-14 00:00:00

abstract：BACKGROUND:FGF23 controls serum l,25(OH)2D3 levels and phosphate homeostasis. This study evaluates the effects of ferritin on intact PTH, FGF23, and l,25(OH)2D3 in patients with major thalassemia. It also evaluates FGF23 changes in patients with hypoparathyroidism to clarify the interaction between FGF23 and PTH in the...

journal_title：BMC nephrology

authors： Saki F,Salehifar A,Kassaee SR,Omrani GR

更新日期：2020-11-16 00:00:00

abstract：BACKGROUND:As a result of difficulties related to their illness, diagnosis and treatment, patients with end-stage renal disease experience significant emotional and psychological problems, which untreated can have considerable negative impact on their health and wellbeing. Despite evidence that patients desire improved...

journal_title：BMC nephrology

authors： Taylor F,Taylor C,Baharani J,Nicholas J,Combes G

更新日期：2016-08-02 00:00:00

abstract：BACKGROUND:Dose selection is an important step in pharmacokinetic (PK) studies of hemodialysis patients. We propose a simulation-based dose-selection method for PK studies of hemodialysis patients using a subpharmacological dose of oseltamivir as a model drug. METHODS:The concentrations of oseltamivir and its active m...

journal_title：BMC nephrology

authors： Kim DK,Lee JW,Shin KH,Kim S,Oh KH,Kim M,Yu KS,Lee JP,Lim CS,Kim YS,Joo KW

更新日期：2014-03-17 00:00:00

abstract：BACKGROUND:Multiple factors influence timing of dialysis initiation. The impact of supply of nephrology workforce on timing and incidence of dialysis initiation is not well known. METHODS:We determined the number of pediatric and adult nephrologists in each state using data from the American Medical Association and Am...

journal_title：BMC nephrology

authors： Ku E,Johansen KL,Portale AA,Grimes B,Hsu CY

更新日期：2015-01-15 00:00:00

abstract：BACKGROUND:Rituximab is widely used in kidney transplantation. However, it is not clear whether the conventional doses of maintenance immunosuppressant in rituximab-treated kidney transplantation (KT) are appropriate. In our previous study, decreasing mycophenolate mofetil (MMF) dose due to infection did not increase t...

journal_title：BMC nephrology

authors： Baek CH,Kim H,Yu H,Shin E,Cho H,Yang WS,Han DJ,Park SK

更新日期：2015-12-04 00:00:00

abstract：BACKGROUND:Lower serum bicarbonate, mainly due to the modern Western-style diet, and renal hyperfiltration (RHF) are both independently associated with higher mortality in the general population with preserved renal function. The objective of this study was to evaluate the association between serum bicarbonate and RHF....

journal_title：BMC nephrology

authors： Park M,So R,Joo KW,Yoon HJ

更新日期：2016-01-06 00:00:00

abstract：BACKGROUND:Experimental studies showed that 25-hydroxy-vitamin D [25(OH)D] deficiency (defined as 25-hydroxy-vitamin D < 15 ng/ml) has been associated with CKD progression. Patients with IgA nephropathy have an exceptionally high rate of severe 25(OH)D deficiency; however, it is not known whether this deficiency is a r...

journal_title：BMC nephrology

authors： Li XH,Huang XP,Pan L,Wang CY,Qin J,Nong FW,Luo YZ,Wu Y,Huang YM,Peng X,Yang ZH,Liao YH

更新日期：2016-11-02 00:00:00

abstract：BACKGROUND:Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in patients with chronic kidney disease (CKD). Cardiovascular risk assessment in this population is hampered by the failure of traditional risk factors to fully account for the elevated CVD risk (reverse epidemiology effect) and the...

journal_title：BMC nephrology

authors： Junyent M,Martínez M,Borràs M,Coll B,Valdivielso JM,Vidal T,Sarró F,Roig J,Craver L,Fernández E

更新日期：2010-07-07 00:00:00

abstract：BACKGROUND:Metabolic acidosis leads to chronic kidney disease (CKD) progression. The guidelines recommend a lower limit of serum bicarbonate level, but no upper limit. For serum bicarbonate level to be clinically useful as a therapeutic target marker, it is necessary to investigate the target serum bicarbonate level wi...

journal_title：BMC nephrology

authors： Kanda E,Ai M,Yoshida M,Kuriyama R,Shiigai T

更新日期：2013-01-09 00:00:00