Increased blood pressure in adult offspring of families with Balkan endemic nephropathy: a prospective study.

abstract：BACKGROUND:Indoleamine 2, 3-dioxygenase (IDO) is an immunomodulatory molecule that has been implicated in several biological processes. Although IDO has been linked with some renal diseases, its role in renal fibrosis is still unclear. Because IDO may be modulated by TGF-β1, a potent fibrogenic molecule, we hypothesize...

journal_title：BMC nephrology

authors： Matheus LHG,Simão GM,Amaral TA,Brito RBO,Malta CS,Matos YST,Santana AC,Rodrigues GGC,Albejante MC,Bach EE,Dalboni MA,Camacho CP,Dellê H

更新日期：2017-09-06 00:00:00

abstract：BACKGROUND:Nephrotic syndrome (NS) is pathological condition characterized by heavy proteinuria. Our study investigates hypothesis that change in cell proliferation of proximal tubules influences primary cilia structure and function and promotes cystogenesis in congenital nephrotic syndrome of the Finnish type (CNF) an...

journal_title：BMC nephrology

authors： Saraga M,Vukojević K,Krželj V,Puretić Z,Bočina I,Durdov MG,Weber S,Dworniczak B,Ljubanović DG,Saraga-Babić M

更新日期：2014-01-08 00:00:00

abstract：BACKGROUND:The currently available data with respect to the association between vitamin D receptor (VDR) gene polymorphism and risk to urolithiasis are inconclusive and inconsistent. Hence, an exhaustive meta-analysis can solve the discrepancies and provide a hint for upcoming investigations. Herein, a meta-analysis wa...

journal_title：BMC nephrology

authors： Imani D,Razi B,Khosrojerdi A,Lorian K,Motallebnezhad M,Rezaei R,Aslani S

更新日期：2020-07-10 00:00:00

abstract：BACKGROUND:Anaemia of chronic kidney disease increases the risk of death and adverse events, but can be managed using erythropoiesis stimulating agents (ESAs). However, recent evidence suggests that targeting a higher haemoglobin concentration ([Hb]) increases mortality risk, and both higher [Hb] targets and ESA doses ...

journal_title：BMC nephrology

authors： McMahon LP,Cai MX,Baweja S,Holt SG,Kent AB,Perkovic V,Leikis MJ,Becker GJ

更新日期：2012-06-15 00:00:00

abstract：BACKGROUND:Previous studies have not described the relationship between reducing radial artery diameter as well as increasing age and functional maturation of the radio-cephalic arteriovenous fistula (RCAVF) and no data identify these as linear relationship. The objective of this study was to perform trend analysis to ...

journal_title：BMC nephrology

authors： Wan ZM,Hu B,Lai QQ,Gao XJ,Tu B,Zhou Y,Zhao WB

更新日期：2020-06-22 00:00:00

abstract：BACKGROUND:Hepatocyte growth factor (HGF) counteracts peritoneal fibrosis in animal models and in-vitro studies, but no study explored effluent HGF in peritoneal dialysis (PD) patients with ultrafiltration failure (UFF). Our aim was to assess the relationship between effluent HGF with UF profile, free water transport (...

journal_title：BMC nephrology

authors： Bernardo AP,Oliveira JC,Santos O,Carvalho MJ,Cabrita A,Rodrigues A

更新日期：2014-12-17 00:00:00

abstract：BACKGROUND:Local renal ischemia is regarded as an important factor in the development of contrast-induced nephropathy (CIN). Mannose-binding lectin (MBL) is involved in the tissue damage during experimental ischemia/reperfusion injury of the kidneys. The aim of the present study was to investigate the association of MB...

journal_title：BMC nephrology

authors： Osthoff M,Piezzi V,Klima T,Christ A,Marana I,Hartwiger S,Breidthardt T,Marenzi G,Trendelenburg M,Mueller C

更新日期：2012-09-03 00:00:00

abstract：BACKGROUND:Icodextrin is a starch-derived, water soluble glucose polymer, which is used as an alternative to glucose in order to enhance dialytic fluid removal in peritoneal dialysis patients. Although the safety and efficacy of icodextrin is well-established, its use in everyday clinical practice has been associated w...

journal_title：BMC nephrology

authors： Liakopoulos V,Georgianos PI,Demirtzi P,Vaios V,Kalathas T,Zebekakis PE

更新日期：2018-10-25 00:00:00

abstract：BACKGROUND:There is conflicting evidence of benefit versus harm for warfarin anticoagulation in hemodialysis patients with atrial fibrillation. This equipoise may be explained by suboptimal Time in Therapeutic Range (TTR), which correlates well with thromboembolic and bleeding complications. This study aimed to compare...

journal_title：BMC nephrology

authors： Bahbahani H,AlTurki A,Dawas A,Lipman ML

更新日期：2018-01-08 00:00:00

abstract：BACKGROUND:Rehabilitation effects of exercise training on adults with chronic kidney disease (CKD) have been generally recognised; however, the effects of exercise training on proteinuria have been underexplored. Our aim was to explore the effects of exercise training on proteinuria in adult CKD patients without renal ...

journal_title：BMC nephrology

authors： Yang L,Wu X,Wang Y,Wang C,Hu R,Wu Y

更新日期：2020-05-11 00:00:00

abstract：BACKGROUND:Alport syndrome and ANCA-associated vasculitis are both rare diseases. The co-existence of these two conditions has never been reported. There is no obvious pathogenic link between these two glomerular diseases. The management of this case highlights the importance of a systematic approach when investigating...

journal_title：BMC nephrology

authors： Gillion V,Jadoul M,Aydin S,Godefroid N

更新日期：2017-03-29 00:00:00

abstract：BACKGROUND:Gitelman syndrome (GS) is an autosomal recessive inherited salt-losing tubulopathy (SLT). Here, we describe, for the first time, a case of GS without Gitelman-like features and with concomitant kidney stones, cysts and diabetic nephropathy (DN). CASE PRESENTATION:We described a male patient had a 19-year hi...

journal_title：BMC nephrology

authors： Chen Q,Wang X,Min J,Wang L,Mou L

更新日期：2021-01-07 00:00:00

abstract：BACKGROUND:To measure health-related and care-related quality of life among informal caregivers of older people with end-stage kidney disease (ESKD), and to determine the association between caregiver quality of life and care recipient's treatment type. METHODS:A prospective cross-sectional study was conducted. Three ...

journal_title：BMC nephrology

authors： Shah KK,Murtagh FEM,McGeechan K,Crail SM,Burns A,Morton RL

更新日期：2020-05-04 00:00:00

abstract：BACKGROUND:Urinary Ca2+ excretion increases with dietary NaCl. NaCl-induced calciuria may be associated with hypertension, urinary stone formation and osteoporosis, but its mechanism and long-term effects are not fully understood. This study examined alterations in the expressions of renal Ca2+ transporters, channels a...

journal_title：BMC nephrology

authors： Yatabe MS,Yatabe J,Takano K,Murakami Y,Sakuta R,Abe S,Sanada H,Kimura J,Watanabe T

更新日期：2012-12-02 00:00:00

abstract：BACKGROUND:Corticosteroids are widely used to reduce the urine protein levels of patients with immunoglobulin A nephropathy (IgAN). However, their potential preventive effects on end-stage kidney disease (ESKD) are unclear. METHODS:We previously performed a large-scale, long-term multicenter cohort study of patients w...

journal_title：BMC nephrology

authors： Tsunoda R,Usui J,Hoshino J,Fujii T,Suzuki S,Takaichi K,Ubara Y,Yamagata K

更新日期：2018-09-06 00:00:00

abstract：BACKGROUND:Providing patient-centered care needs in patients with chronic renal failure undergoing hemodialysis is important in inspiring their confidence to continue their treatment and promote their mental and social health. Therefore, recognizing the concept of care from the viewpoint of these patients can be helpfu...

journal_title：BMC nephrology

authors： Shahgholian N,Yousefi H

更新日期：2018-11-26 00:00:00

abstract：BACKGROUND:Atypical hemolytic uremic syndrome (aHUS) is a rare, genetically-mediated systemic disease most often caused by chronic, uncontrolled complement activation that leads to systemic thrombotic microangiopathy (TMA) and renal and other end-organ damage. METHODS:The global aHUS Registry, initiated in April 2012,...

journal_title：BMC nephrology

authors： Licht C,Ardissino G,Ariceta G,Cohen D,Cole JA,Gasteyger C,Greenbaum LA,Johnson S,Ogawa M,Schaefer F,Vande Walle J,Frémeaux-Bacchi V

更新日期：2015-12-10 00:00:00

abstract：BACKGROUND:Estimates of the incidence of glomerulonephritis (GN) and end-stage renal disease (ESRD) in an Iraqi population are compared with the United States (US) and Jordan. METHODS:The study set consist of renal biopsies performed in 2012 and 2013 in the Kurdish provinces of Northern Iraq. The age specific and age ...

journal_title：BMC nephrology

authors： Ali AA,Sharif DA,Almukhtar SE,Abd KH,Saleem ZSM,Hughson MD

更新日期：2018-10-11 00:00:00

abstract：BACKGROUND:Anabolic-androgenic steroids and growth hormone are among the most commonly used supplements by sportsmen and sportswomen. The aim of this systematic review is to collect and report available data about renal safety of anabolic-androgenic steroids and growth hormone (GH). METHODS:The search strategy was in ...

journal_title：BMC nephrology

authors： Davani-Davari D,Karimzadeh I,Khalili H

更新日期：2019-05-31 00:00:00

abstract：BACKGROUND:Fibrillary glomerulonephritis (FGN) is distinguished from amyloidosis by thicker fibrils and the lack of staining with histochemical dyes typically reactive with amyloid. However, congophilic FGN has been proposed recently and adding laser microdissection followed by mass spectrometry (LMD/MS) to conventiona...

journal_title：BMC nephrology

authors： Adachi M,Kitamura M,Muta K,Maekawa A,Uramatsu T,Tadokoro M,Funakoshi S,Hisano S,Kuwahara N,Shimizu A,Mukae H,Nishino T

更新日期：2020-05-24 00:00:00

abstract：BACKGROUND:TAFRO syndrome is a clinical subtype of idiopathic multicentric Castleman disease (iMCD) that is characterized by thrombocytopenia, anasarca, fever, reticulin myelofibrosis (or renal dysfunction), and organomegaly. TAFRO syndrome has only recently been described, and many clinicians are unaware of this disea...

journal_title：BMC nephrology

authors： Zhou Q,Zhang Y,Zhou G,Zhu J

更新日期：2020-11-23 00:00:00

abstract：BACKGROUND:Patients with end-stage renal disease (ESRD) exhibit a premature aging phenotype of immune system, which is recently concerned as a significant factor for increased risk of various morbidities. Nevertheless, there are few dates explicating the relevancy of T cell senescence to mortality. In this study, we pr...

journal_title：BMC nephrology

authors： Xiang F,Chen R,Cao X,Shen B,Chen X,Ding X,Zou J

更新日期：2020-07-13 00:00:00

abstract：BACKGROUND:MicroRNAs have been demonstrated to play an important role in the pathogenesis of diabetic nephropathy (DN). In this study, we investigated both the repertoire of miRNAs in the kidneys of patients with DN and their potential regulatory role in inflammation-mediated glomerular endothelial injury. METHODS:The...

journal_title：BMC nephrology

authors： Huang Y,Liu Y,Li L,Su B,Yang L,Fan W,Yin Q,Chen L,Cui T,Zhang J,Lu Y,Cheng J,Fu P,Liu F

更新日期：2014-09-02 00:00:00

abstract：BACKGROUND:Self-management education needs have not been assessed in patients with complex co-morbid conditions such as diabetes and chronic kidney disease (CKD). The objectives of this study were to 1) determine the self-management education needs for patients with co-morbid diabetes and CKD and 2) co-develop an educa...

journal_title：BMC nephrology

authors： Zimbudzi E,Lo C,Kerr PG,Zoungas S

更新日期：2019-04-02 00:00:00

abstract：:In a recent study published by the National Project Team on chronic kidney diseases of unknown origin in Sri Lanka, identified cadmium as a major risk factor but strong conclusions were not made as the identified environmental toxins were within the permissible levels.Sri Lankan food consumption pattern is different s...

journal_title：BMC nephrology

authors： Jayalal TB

更新日期：2015-12-23 00:00:00

abstract：BACKGROUND:Glucocorticoids (GCs) are frequently used to treat glomerular diseases but are associated with multiple adverse effects including hypothalamic-pituitary-adrenal axis inhibition that can lead to adrenal insufficiency (AI) on withdrawal. There is no agreed GC tapering strategy to minimise this risk. METHODS:T...

journal_title：BMC nephrology

authors： Karangizi AHK,Al-Shaghana M,Logan S,Criseno S,Webster R,Boelaert K,Hewins P,Harper L

更新日期：2019-05-06 00:00:00

abstract：BACKGROUND:Studies suggest 24-h blood pressure (BP) variability has prognostic value for cardiovascular disease. Several factors associated with high 24-h BP variability are also common among individuals with chronic kidney disease (CKD). We hypothesized 24-h BP variability would be higher for individuals with versus w...

journal_title：BMC nephrology

authors： Tanner RM,Shimbo D,Dreisbach AW,Carson AP,Fox ER,Muntner P

更新日期：2015-06-18 00:00:00

abstract：BACKGROUND:Acute kidney injury (AKI) places a heavy burden on the healthcare system in China and is usually misdiagnosed. However, there are limited studies that have described the epidemiology and diagnosis of AKI in China. The aim of this study was to describe the incidence and diagnosis of AKI in hospitalized adult ...

journal_title：BMC nephrology

authors： Cheng X,Wu B,Liu Y,Mao H,Xing C

更新日期：2017-06-24 00:00:00

abstract：BACKGROUND:This study will assess measures of vascular health and inflammation in Aboriginal Australian adults with chronic kidney disease (CKD), and determine if intensive periodontal intervention improves cardiovascular health, progression of renal disease and periodontal health over a 24-month follow-up. METHODS:Th...

journal_title：BMC nephrology

authors： Jamieson L,Skilton M,Maple-Brown L,Kapellas K,Askie L,Hughes J,Arrow P,Cherian S,Fernandes D,Pawar B,Brown A,Boffa J,Hoy W,Harris D,Mueller N,Cass A

更新日期：2015-10-31 00:00:00

abstract：BACKGROUND:The possibility of clearing Cell-free Plasma Hemoglobin (CPH) from human plasma may appear attractive, especially when considering the noxious effects that CPH has on the immune function and the renal damage caused by its filtration. The existence of the so-called High Cut-Off (HCO) filters, possessing pores...

journal_title：BMC nephrology

authors： Cucchiari D,Reverter E,Blasco M,Molina-Andujar A,Carpio A,Sanz M,Escorsell A,Fernández J,Poch E

更新日期：2018-10-04 00:00:00