Hepatocyte growth factor signalizes peritoneal membrane failure in peritoneal dialysis.

abstract：BACKGROUND:Interleukin 17 is a proinflammatory cytokine involved in immune response after allograft transplantation. IL-17 family of proinflammatory cytokines includes IL-17A and IL-17F. Previous studies have demonstrated that the rs2275913 IL17A and the rs11465553 IL17F gene polymorphism are associated with kidney all...

journal_title：BMC nephrology

authors： Domanski L,Kłoda K,Patrzyk M,Wisniewska M,Safranow K,Sienko J,Sulikowski T,Staniszewska M,Pawlik A

更新日期：2019-04-08 00:00:00

abstract：BACKGROUND:In a recent study we demonstrated that low birth weight (LBW) was associated with increased risk of progressive IgA nephropathy (IgAN). In the present study we investigate whether this could be explained by differences in glomerular morphological parameters. METHODS:The Medical Birth Registry of Norway has ...

journal_title：BMC nephrology

authors： Ruggajo P,Leh S,Svarstad E,Marti HP,Vikse BE

更新日期：2018-10-22 00:00:00

abstract：BACKGROUND:Local renal ischemia is regarded as an important factor in the development of contrast-induced nephropathy (CIN). Mannose-binding lectin (MBL) is involved in the tissue damage during experimental ischemia/reperfusion injury of the kidneys. The aim of the present study was to investigate the association of MB...

journal_title：BMC nephrology

authors： Osthoff M,Piezzi V,Klima T,Christ A,Marana I,Hartwiger S,Breidthardt T,Marenzi G,Trendelenburg M,Mueller C

更新日期：2012-09-03 00:00:00

abstract：BACKGROUND:Previous studies have linked smaller kidney dimensions to increased blood pressure. However, patients with Balkan Endemic Nephropathy (BEN), whose kidneys shrink during the course of the disease, do not manifest increased blood pressure. The authors evaluated the relationship between kidney cortex width, kid...

journal_title：BMC nephrology

authors： Dimitrov PS,Simeonov VA,Tsolova SD,Bonev AG,Georgieva RB,Karmaus WJ

更新日期：2006-08-23 00:00:00

abstract：BACKGROUND:Tolvaptan is a selective vasopressin receptor antagonist. Nitric Oxide (NO) promotes renal water and sodium excretion, but the effect is unknown in the nephron's principal cells. In a dose-response study, we measured the effect of tolvaptan on renal handling of water and sodium and systemic hemodynamics, dur...

journal_title：BMC nephrology

authors： Al Therwani S,Rosenbæk JB,Mose FH,Bech JN,Pedersen EB

更新日期：2017-03-13 00:00:00

abstract：BACKGROUND:Acute kidney injury (AKI) is a common clinical problem. Studies have documented the incidence of AKI in a variety of populations but to date we do not believe the real incidence of AKI has been accurately documented in a district general hospital setting.The aim here was to describe the detected incidence of...

journal_title：BMC nephrology

authors： Bedford M,Stevens PE,Wheeler TW,Farmer CK

更新日期：2014-06-21 00:00:00

abstract：BACKGROUND:Autosomal dominant polycystic kidney disease (ADPKD) is a hereditary disease characterized by the presence of renal cysts. Over time the expanding cysts lead to progressive renal failure. The use of tolvaptan, a V2-receptor antagonist, was recently approved in ADPKD patients. It was demonstrated that tolvapt...

journal_title：BMC nephrology

authors： Pellegrino AM,Annicchiarico Petruzzelli L,Riccio E,Pisani A

更新日期：2019-11-21 00:00:00

abstract：BACKGROUND:The prevalence of chronic kidney disease (CKD) is increasing worldwide and in Africa. Health related quality of life (QOL) has become an essential outcome measure for patients with CKD and end stage renal disease (ESRD). There is growing interest worldwide in QOL of CKD patients but paucity of data in Ghana....

journal_title：BMC nephrology

authors： Tannor EK,Norman BR,Adusei KK,Sarfo FS,Davids MR,Bedu-Addo G

更新日期：2019-04-08 00:00:00

abstract：BACKGROUND:Primary hyperoxaluria type 1 is a rare autosomal recessive disease of glyoxylate metabolism caused by a defect in the liver-specific peroxisomal enzyme alanine:glyoxylate aminotransferase (AGT) that leads to hyperoxaluria, recurrent urolithiasis, and nephrocalcinosis. METHODS:Two unrelated patients with rec...

journal_title：BMC nephrology

authors： Li GM,Xu H,Shen Q,Gong YN,Fang XY,Sun L,Liu HM,An Y

更新日期：2014-06-17 00:00:00

abstract：BACKGROUND:Evidence suggests that exercise training for hemodialysis patients positively improves morbidity and mortality outcomes, yet exercise programs remain rare and are not systematically incorporated into care. We developed a research-based film, Fit for Dialysis, designed to introduce, motivate, and sustain exer...

journal_title：BMC nephrology

authors： Kontos P,Alibhai SM,Miller KL,Brooks D,Colobong R,Parsons T,Jassal SV,Thomas A,Binns M,Naglie G

更新日期：2017-01-26 00:00:00

abstract：BACKGROUND:Levetiracetam is a frequently used drug in the therapy of partial onset, myoclonic and generalized tonic-clonic seizures. The main route of elimination is via the kidneys, which eliminate 66% of the unchanged drug as well as 24% as inactive metabolite that stems from enzymatic hydrolysis. Therefore dose adju...

journal_title：BMC nephrology

authors： Bahte SK,Hiss M,Lichtinghagen R,Kielstein JT

更新日期：2014-04-16 00:00:00

abstract：BACKGROUND:Fabry disease (FD) is an X-linked lysosomal storage disorder caused by mutations of the GLA gene, followed by deficiency in α-galactosidase A (α-gal) activity. Nephrotic syndrome, as the renal phenotype of FD, is unusual. Here, we report the rare case of a patient with FD with nephrotic syndrome whose protei...

journal_title：BMC nephrology

authors： Fujisawa H,Nakayama Y,Nakao S,Yamamoto R,Kurokawa Y,Nakamura N,Nagata A,Tsukimura T,Togawa T,Sakuraba H,Fukami K

更新日期：2019-12-17 00:00:00

abstract：BACKGROUND:The possibility of clearing Cell-free Plasma Hemoglobin (CPH) from human plasma may appear attractive, especially when considering the noxious effects that CPH has on the immune function and the renal damage caused by its filtration. The existence of the so-called High Cut-Off (HCO) filters, possessing pores...

journal_title：BMC nephrology

authors： Cucchiari D,Reverter E,Blasco M,Molina-Andujar A,Carpio A,Sanz M,Escorsell A,Fernández J,Poch E

更新日期：2018-10-04 00:00:00

abstract：BACKGROUND:Autosomal dominant polycystic kidney disease (ADPKD) is one of the most common hereditary kidney diseases that frequently result in renal failure. In this cross-sectional observational cohort study, we evaluated urinary angiotensinogen (AGT) as a potential biomarker to assess renal function in ADPKD. METHOD...

journal_title：BMC nephrology

authors： Park HC,Kang AY,Jang JY,Kim H,Han M,Oh KH,Kim SH,Noh JW,Cheong HI,Hwang YH,Ahn C

更新日期：2015-06-20 00:00:00

abstract：BACKGROUND:Chronic kidney disease (CKD) is increasingly being recognized as a predictor for both end-stage renal disease and cardiovascular disease. The present study, conducted on individuals from a community in Arita, Japan, was designed to evaluate biomarkers that can be used to determine the associated factors for ...

journal_title：BMC nephrology

authors： Takamatsu N,Abe H,Tominaga T,Nakahara K,Ito Y,Okumoto Y,Kim J,Kitakaze M,Doi T

更新日期：2009-10-27 00:00:00

abstract：BACKGROUND:The patterns, performance characteristics, and yield of diagnostic tests ordered for the evaluation of acute kidney injury (AKI) have not been rigorously evaluated. METHODS:We characterized the frequency of AKI diagnostic testing for urine, blood, radiology, and pathology tests in all adult inpatients who w...

journal_title：BMC nephrology

authors： Leaf DE,Srivastava A,Zeng X,McMahon GM,Croy HE,Mendu ML,Kachalia A,Waikar SS

更新日期：2016-01-15 00:00:00

abstract：BACKGROUND:Sclerostin is a paracrine acting factor, which is expressed in the osteocytes and articular chondrocytes. Sclerostin decreases the osteoblast-related bone formation through the inhibition of the Wnt/β-catenin pathway. Osteocytes also express the Calcium sensing receptor which is a target for cinacalcet. The ...

journal_title：BMC nephrology

authors： Kuczera P,Adamczak M,Więcek A

更新日期：2016-11-15 00:00:00

abstract：BACKGROUND:Patients with end-stage renal disease (ESRD) under hemodialysis (HD) are at greater risks of infectious spondylitis (IS), but there is no reliable predictor that facilitate early detection of this relatively rare and insidious disease. METHODS:A retrospective review of the medical records from patients with...

journal_title：BMC nephrology

authors： Lu KL,Huang WH,Lu YA,Lin CY,Wu HH,Hsu CW,Weng CH,Wu CY,Wu IW,Wu MY,Yen TH,Yang HY

更新日期：2019-08-16 00:00:00

abstract：BACKGROUND:Serum cystatin C (ScysC) may help predicting cardiovascular outcome not only through its ability to detect renal dysfunction but also through its potential connection to others factors that are directly related to cardiovascular diseases. We explored the potential association of ScysC with arterial stiffness...

journal_title：BMC nephrology

authors： Dinic M,Maillard N,Thibaudin D,Jannot M,Masson I,Alamartine E,Mariat C

更新日期：2014-12-11 00:00:00

abstract：BACKGROUND:Very less is known about health-related quality of life (HRQOL) among patients with kidney diseases in Nepal. This study examined HRQOL among haemodialysis and kidney transplant recipients in Nepal. METHODS:The Nepali version of World Health Organization Quality of Life Instruments -(WHOQOL-BREF) questionna...

journal_title：BMC nephrology

authors： Ranabhat K,Khanal P,Mishra SR,Khanal A,Tripathi S,Sigdel MR

更新日期：2020-10-12 00:00:00

abstract：BACKGROUND:Age and number of recipients in need of kidney re-transplantation are increasing. Re-transplantation practices and outcomes in elderly recipients are not previously explored. We aimed to retrospectively evaluate the outcomes of recipients 65 years and older receiving their second deceased donor allograft. M...

journal_title：BMC nephrology

authors： Heldal K,Hartmann A,Lønning K,Leivestad T,Reisæter AV,Line PD,Holdaas H,Midtvedt K

更新日期：2017-01-11 00:00:00

abstract：BACKGROUND:There is a perception that kidney transplant recipients transferred from pediatric centers to adult care have an increased risk of graft loss. It is not clear whether young adults transplanted in adult centers also suffer from high graft loss rates. METHODS:We examined death censored graft survival in 3 coh...

journal_title：BMC nephrology

authors： Kiberd JA,Acott P,Kiberd BA

更新日期：2011-10-07 00:00:00

abstract：BACKGROUND:To assess whether serum osteoprotegerin (OPG) and/or fetuin-A predict mortality and cardiovascular (CV) morbidity and mortality in hemodialysis patients. METHODS:Multicenter, observational, prospective study that included 220 hemodialysis patients followed up for up to 6 years. Serum OPG and fetuin-A levels...

journal_title：BMC nephrology

authors： Collado S,Coll E,Nicolau C,Azqueta M,Pons M,Cruzado JM,de la Torre B,Deulofeu R,Mojal S,Pascual J,Cases A

更新日期：2017-09-07 00:00:00

abstract：BACKGROUND:Neutrophil gelatinase associated lipocalin (NGAL) is a highly predictive biomarker of acute kidney injury. To understand the role of NGAL in renal injury during sepsis, we investigated the temporal changes and biological sources of NGAL in a rat model of acute kidney injury, and explored the relationship bet...

journal_title：BMC nephrology

authors： Han M,Li Y,Liu M,Li Y,Cong B

更新日期：2012-06-27 00:00:00

abstract：BACKGROUND:Obesity is a well-established risk factor for atherosclerosis. However, it is unknown which measure of adiposity best relates to atherosclerosis in relatively lean maintenance hemodialysis (MHD) patients. We aimed to explore and compare the associations between different adiposity indices reflecting general,...

journal_title：BMC nephrology

authors： Zhou C,Peng H,Yuan J,Lin X,Zha Y,Chen H

更新日期：2018-08-16 00:00:00

abstract：BACKGROUND:The short-term efficacy of tolvaptan in patients with autosomal dominant polycystic kidney disease (ADPKD) has been demonstrated across several phase 3 trials, while the ADPKD Outcomes Model (ADPKD-OM) represents a validated approach to predict natural disease progression over a lifetime horizon. This study ...

journal_title：BMC nephrology

authors： Bennett H,McEwan P,Hamilton K,O'Reilly K

更新日期：2019-04-23 00:00:00

abstract：BACKGROUND:This study will assess measures of vascular health and inflammation in Aboriginal Australian adults with chronic kidney disease (CKD), and determine if intensive periodontal intervention improves cardiovascular health, progression of renal disease and periodontal health over a 24-month follow-up. METHODS:Th...

journal_title：BMC nephrology

authors： Jamieson L,Skilton M,Maple-Brown L,Kapellas K,Askie L,Hughes J,Arrow P,Cherian S,Fernandes D,Pawar B,Brown A,Boffa J,Hoy W,Harris D,Mueller N,Cass A

更新日期：2015-10-31 00:00:00

abstract：BACKGROUND:The current practice concerning timing, mode, and dose of renal replacement therapy (RRT) in patients with metformin-associated lactic acidosis (MALA) with renal failure remains unknown. To investigate whether serum lactate level and prescription pattern of RRT are associated with mortality in patients with ...

journal_title：BMC nephrology

authors： Yeh HC,Ting IW,Tsai CW,Wu JY,Kuo CC

更新日期：2017-07-10 00:00:00

abstract：INTRODUCTION:Urinary biomarkers of kidney injury are presumed to reflect renal tubular damage. However, their concentrations may be influenced by other factors, such as hematuria or pyuria. We sought to examine what non-injury related urinalysis factors are associated with urinary biomarker levels. METHODS:We examined...

journal_title：BMC nephrology

authors： Nadkarni GN,Coca SG,Meisner A,Patel S,Kerr KF,Patel UD,Koyner JL,Garg AX,Philbrook HT,Edelstein CL,Shlipak M,El-Khoury J,Parikh CR,TRIBE-AKI Consortium Investigators.

更新日期：2017-07-06 00:00:00

abstract：BACKGROUND:Until now, no long-term studies relating serum albumin level to mortality rate in prevalent haemodialysis (HD) patients have been conducted. We aimed to examine the association between serum albumin level and mortality over a 5-year period. METHODS:This study included 781 patients who received maintenance H...

journal_title：BMC nephrology

authors： Chen JB,Cheng BC,Yang CH,Hua MS

更新日期：2016-08-20 00:00:00