Mutational analysis of AGXT in two Chinese families with primary hyperoxaluria type 1.

abstract：BACKGROUND:It remained lack of a kind of contrast-induced acute kidney injury (CI-AKI) model which was widely used in clinical practice and comparable to CI-AKI in humans. METHODS:Fifty Sprague-Dawley rats were divided into five groups of 10 rats each: (1) sham group (normal saline [NS] + NS); (2) NS plus low osmolali...

journal_title：BMC nephrology

authors： Liu YH,Xue JH,Wu DX,Bei WJ,Wang K,Liu Y,Chen JY,Tan N

更新日期：2019-07-04 00:00:00

abstract：BACKGROUND:Ghrelin, a gastric orexigenic peptide, and body mass index (BMI) are known as inversely associated to each other and are both linked to cardiovascular (CV) risk and mortality in maintenance hemodialysis (MHD) patients. However, it is unclear whether the interaction between ghrelin and BMI is associated with ...

journal_title：BMC nephrology

authors： Beberashvili I,Sinuani I,Azar A,Shapiro G,Feldman L,Doenyas-Barak K,Stav K,Efrati S

更新日期：2017-01-18 00:00:00

abstract：BACKGROUND:Transplant renal artery dissection is a rare and serious event that can cause allograft dysfunction and activation of the renin-mediated renovascular hypertension. Most cases are induced by percutaneous transluminal angioplasty, arteriosclerotic disease, or fibromuscular dysplasia. We observed a case of tran...

journal_title：BMC nephrology

authors： Hori S,Yoneda T,Tomizawa M,Ichikawa K,Morizawa Y,Nakai Y,Miyake M,Fujimoto K

更新日期：2020-01-29 00:00:00

abstract：BACKGROUND:The management of proliferative lupus nephritis (LN) comprises timely and coordinated immunosuppressive therapy. This study aimed to evaluate and compare the effectiveness and safety profile of low dose mycophenolate mofetil (MMF) and cyclophosphamide (CYC) in induction therapy of LN in Nepalese population. ...

journal_title：BMC nephrology

authors： Sedhain A,Hada R,Agrawal RK,Bhattarai GR,Baral A

更新日期：2018-07-11 00:00:00

abstract：BACKGROUND:The patterns, performance characteristics, and yield of diagnostic tests ordered for the evaluation of acute kidney injury (AKI) have not been rigorously evaluated. METHODS:We characterized the frequency of AKI diagnostic testing for urine, blood, radiology, and pathology tests in all adult inpatients who w...

journal_title：BMC nephrology

authors： Leaf DE,Srivastava A,Zeng X,McMahon GM,Croy HE,Mendu ML,Kachalia A,Waikar SS

更新日期：2016-01-15 00:00:00

abstract：BACKGROUND:Fabry disease (FD) is an X-linked lysosomal storage disorder caused by mutations of the GLA gene, followed by deficiency in α-galactosidase A (α-gal) activity. Nephrotic syndrome, as the renal phenotype of FD, is unusual. Here, we report the rare case of a patient with FD with nephrotic syndrome whose protei...

journal_title：BMC nephrology

authors： Fujisawa H,Nakayama Y,Nakao S,Yamamoto R,Kurokawa Y,Nakamura N,Nagata A,Tsukimura T,Togawa T,Sakuraba H,Fukami K

更新日期：2019-12-17 00:00:00

abstract：BACKGROUND:Chronic kidney disease (CKD) is a common comorbid condition in coronary heart disease (CHD). CKD predisposes the patient to acute kidney injury (AKI) during hospitalization. Data on awareness of kidney dysfunction among CHD patients and their treating physicians are lacking. In the current cross-sectional an...

journal_title：BMC nephrology

authors： Wagner M,Wanner C,Schich M,Kotseva K,Wood D,Hartmann K,Fette G,Rücker V,Oezkur M,Störk S,Heuschmann PU

更新日期：2017-10-25 00:00:00

abstract：BACKGROUND:S100A12 protein is an endogenous receptor ligand for advanced glycation end products. In this study, the plasma S100A12 level was assessed as an independent predictor of mortality, and its utility in clinical settings was examined. METHODS:In a previous cross-sectional study, plasma S100A12 levels were meas...

journal_title：BMC nephrology

authors： Shiotsu Y,Mori Y,Nishimura M,Hatta T,Imada N,Maki N,Iida K,Iwamoto N,Matsuoka E,Tamagaki K,Kosaki A

更新日期：2013-01-16 00:00:00

abstract：BACKGROUND:Some nephrologists have advocated an individualized approach to the prescription of bicarbonate hemodialysis. However, the utility of monthly serum bicarbonate levels for guiding and evaluating such treatment decisions has not been evaluated. We sought to define the variability of these measurements and to d...

journal_title：BMC nephrology

authors： Patel R,Paredes W,Hall CB,Nader MA,Sapkota D,Folkert VW,Abramowitz MK

更新日期：2015-12-21 00:00:00

abstract：BACKGROUND:Recipients of living donor renal transplantation are typically considered to have a relatively lower immunological risk. This retrospective study aimed to compare the therapeutic efficacy and safety between rabbit antithymocyte globulin (rATG) or interleukin-2 receptor antagonist (IL2-RA) induction therapies...

journal_title：BMC nephrology

authors： Qiu J,Li J,Chen G,Huang G,Fu Q,Wang C,Chen L

更新日期：2019-03-22 00:00:00

abstract：BACKGROUND:To establish a model of chronic renal fibrosis following acute kidney injury (AKI) in BALB/c mice and to observe the effect of AKI on podocyte injury and chronic fibrosis of the kidney. Additional aims included using the model to explore the role of podocyte injury in AKI and post-injury fibrosis. METHODS:F...

journal_title：BMC nephrology

authors： Chen Y,Lin L,Tao X,Song Y,Cui J,Wan J

更新日期：2019-03-28 00:00:00

abstract：BACKGROUND:Decreased heat shock protein 27 (HSP27) participates in many processes that are involved in cardiovascular (CV) disease. The objective of the study was to evaluate if HSP27 level was predictive of mortality as well as to evaluate factors associated with HSP27 level in a group of patients treated with HD. ME...

journal_title：BMC nephrology

authors： Jaroszyński A,Jaroszyńska A,Zaborowski T,Drelich-Zbroja A,Zapolski T,Dąbrowski W

更新日期：2018-12-17 00:00:00

abstract：BACKGROUND:Anaemia is a known risk factor for cardiovascular disease and treating anaemia in chronic kidney disease (CKD) may improve outcomes. However, little is known about the scope to improve primary care management of anaemia in CKD. METHODS:An observational study (N = 1,099,292) with a nationally representative ...

journal_title：BMC nephrology

authors： Dmitrieva O,de Lusignan S,Macdougall IC,Gallagher H,Tomson C,Harris K,Desombre T,Goldsmith D

更新日期：2013-01-25 00:00:00

abstract：BACKGROUND:Emerging evidence of psychosocial problems in CKD patients has led to an acceptance that a focus on the emotional wellbeing of the patient should be included in the provision of comprehensive CKD care. It is unclear if an increased attention for psychosocial needs in guidelines and policy documents has led t...

journal_title：BMC nephrology

authors： Seekles ML,Ormandy P,Coyne E

更新日期：2019-03-21 00:00:00

abstract：BACKGROUND:In patients with autosomal dominant polycystic kidney disease (ADPKD), malnutrition may develop as renal function declines and the abdominal organs become enlarged. We investigated the relationship of intra-abdominal mass with nutritional status. METHODS:This cross-sectional study was performed at a tertiar...

journal_title：BMC nephrology

authors： Ryu H,Kim H,Park HC,Kim H,Cho EJ,Lee KB,Chung W,Oh KH,Cho JY,Hwang YH,Ahn C

更新日期：2017-01-14 00:00:00

abstract：BACKGROUND:Very less is known about health-related quality of life (HRQOL) among patients with kidney diseases in Nepal. This study examined HRQOL among haemodialysis and kidney transplant recipients in Nepal. METHODS:The Nepali version of World Health Organization Quality of Life Instruments -(WHOQOL-BREF) questionna...

journal_title：BMC nephrology

authors： Ranabhat K,Khanal P,Mishra SR,Khanal A,Tripathi S,Sigdel MR

更新日期：2020-10-12 00:00:00

abstract：BACKGROUND:Patients with chronic kidney diseases (CKD) on haemodialysis (HD) have high morbidity and mortality rates, which are also due to the inherent risks associated with nephropathy. Non-adherence (NA) to the different demands of the treatment can have consequences for the outcome of patients undergoing HD; nevert...

journal_title：BMC nephrology

authors： Dantas LGG,de Seixas Rocha M,Junior JAM,Paschoalin EL,Paschoalin SRKP,Sampaio Cruz CM

更新日期：2019-11-06 00:00:00

abstract：BACKGROUND:Polycystic Kidney Disease (PKD) kidneys exhibit increased extracellular matrix (ECM) collagen expression and metalloproteinases (MMPs) activity. We investigated the role of these increases on cystic disease progression in PKD kidneys. METHODS:We examined the role of type I collagen (collagen I) and membrane...

journal_title：BMC nephrology

authors： Liu B,Li C,Liu Z,Dai Z,Tao Y

更新日期：2012-09-11 00:00:00

abstract：BACKGROUND:Treatment of idiopathic membranous nephropathy with nephrotic syndrome is still controversial. There is currently little known about the clinical use of renal biomarkers which may explain contradictory results obtained from clinical trials. In order to assess whether IgG-uria can predict the outcome in membr...

journal_title：BMC nephrology

authors： Bazzi C,Rizza V,Casellato D,Tofik R,Berg AL,Gallieni M,D'Amico G,Bakoush O

更新日期：2014-05-08 00:00:00

abstract：BACKGROUND:Estimates of the incidence of glomerulonephritis (GN) and end-stage renal disease (ESRD) in an Iraqi population are compared with the United States (US) and Jordan. METHODS:The study set consist of renal biopsies performed in 2012 and 2013 in the Kurdish provinces of Northern Iraq. The age specific and age ...

journal_title：BMC nephrology

authors： Ali AA,Sharif DA,Almukhtar SE,Abd KH,Saleem ZSM,Hughson MD

更新日期：2018-10-11 00:00:00

abstract：BACKGROUND:This study will assess measures of vascular health and inflammation in Aboriginal Australian adults with chronic kidney disease (CKD), and determine if intensive periodontal intervention improves cardiovascular health, progression of renal disease and periodontal health over a 24-month follow-up. METHODS:Th...

journal_title：BMC nephrology

authors： Jamieson L,Skilton M,Maple-Brown L,Kapellas K,Askie L,Hughes J,Arrow P,Cherian S,Fernandes D,Pawar B,Brown A,Boffa J,Hoy W,Harris D,Mueller N,Cass A

更新日期：2015-10-31 00:00:00

abstract：BACKGROUND:For chronic hemodialysis, the ideal permanent vascular access is the arteriovenous fistula (AVF). Temporary catheters should be reserved for acute dialysis needs. The AVF is associated with lower infection rates, better clinical results, and a higher quality of life and survival when compared to temporary ca...

journal_title：BMC nephrology

authors： Bonfante GM,Gomes IC,Andrade EI,Lima EM,Acurcio FA,Cherchiglia ML

更新日期：2011-11-17 00:00:00

abstract：BACKGROUND:Accurate estimation of glomerular filtration rate (GFR) is important for diagnosis and risk stratification in chronic kidney disease and for selection of living donors. Ethnic differences have required correction factors in the originally developed creatinine-based GFR estimation equations for populations ar...

journal_title：BMC nephrology

authors： Kumar V,Yadav AK,Yasuda Y,Horio M,Kumar V,Sahni N,Gupta KL,Matsuo S,Kohli HS,Jha V

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:ANCA-associated vasculitis is a life-threatening, systemic autoimmune disease. There is an increased risk of organ infarction but in many cases this is asymptomatic. We described here the first reported case of PR3 vasculitis presenting with symptomatic bilateral renal wedge infarction. CASE PRESENTATION:A ...

journal_title：BMC nephrology

authors： Bottomley MJ,Gibson M,Alchi B

更新日期：2019-03-06 00:00:00

abstract：BACKGROUND:Cisplatin is a well-known nephrotoxic antineoplastic drug. Chronic hypokalemic metabolic alkalosis with hypomagnesemia and hypocalciuria is one of the rare complications associated with its use. CASE PRESENTATION:A 42-year-old woman presented with a 20 year-history of hypokalemic metabolic alkalosis with hy...

journal_title：BMC nephrology

authors： Panichpisal K,Angulo-Pernett F,Selhi S,Nugent KM

更新日期：2006-05-24 00:00:00

abstract：BACKGROUND:Patients with end-stage renal disease (ESRD) exhibit a premature aging phenotype of immune system, which is recently concerned as a significant factor for increased risk of various morbidities. Nevertheless, there are few dates explicating the relevancy of T cell senescence to mortality. In this study, we pr...

journal_title：BMC nephrology

authors： Xiang F,Chen R,Cao X,Shen B,Chen X,Ding X,Zou J

更新日期：2020-07-13 00:00:00

abstract：BACKGROUND:Serum p-cresyl sulfate (PCS) associates with cardiovascular disease in patients with chronic kidney disease. PCS concentrations are determined by intestinal uptake of p-cresol, human metabolism to PCS and renal clearance. Whether intestinal uptake of p-cresol itself is directly associated with cardiovascular...

journal_title：BMC nephrology

authors： Poesen R,Viaene L,Verbeke K,Augustijns P,Bammens B,Claes K,Kuypers D,Evenepoel P,Meijers B

更新日期：2014-06-09 00:00:00

abstract：BACKGROUND:Complementary and Alternative Medicines (CAMs) are increasingly practiced in the general population; it is estimated that over 30% of patients with chronic diseases use CAMs on a regular basis. CAMs are also used in hospital settings, suggesting a growing interest in individualized therapies. One potential f...

journal_title：BMC nephrology

authors： Ferraresi M,Clari R,Moro I,Banino E,Boero E,Crosio A,Dayne R,Rosset L,Scarpa A,Serra E,Surace A,Testore A,Colombi N,Piccoli BG

更新日期：2013-06-21 00:00:00

abstract：BACKGROUND:Epithelioid angiomyolipoma is defined as potentially malignant mesenchymal neoplasm, characterized by proliferating epithelioid cells, whereas classic angiomyolipoma, composed of fat, smooth muscle cells and dysmorphic vessels, is defined as a potentially benign. The usual or classic angiomyolipoma is often ...

journal_title：BMC nephrology

authors： Tuma J,Moch H,Stuckmann G,Gysel W,Serra AL

更新日期：2018-05-30 00:00:00

abstract：BACKGROUND:Age and number of recipients in need of kidney re-transplantation are increasing. Re-transplantation practices and outcomes in elderly recipients are not previously explored. We aimed to retrospectively evaluate the outcomes of recipients 65 years and older receiving their second deceased donor allograft. M...

journal_title：BMC nephrology

authors： Heldal K,Hartmann A,Lønning K,Leivestad T,Reisæter AV,Line PD,Holdaas H,Midtvedt K

更新日期：2017-01-11 00:00:00