Abstract:
BACKGROUND:Transplant renal artery dissection is a rare and serious event that can cause allograft dysfunction and activation of the renin-mediated renovascular hypertension. Most cases are induced by percutaneous transluminal angioplasty, arteriosclerotic disease, or fibromuscular dysplasia. We observed a case of transplant renal artery dissection induced by unusual causes during kidney transplantation. CASE PRESENTATION:A 35-year-old woman, whose mother donated a kidney to her, underwent ABO-incompatible living kidney transplantation. The allograft had one renal artery and vein that were anastomosed to the internal iliac artery and external iliac vein, respectively. Although careful handling was performed in all procedures including vascular clamping, Doppler ultrasonography (US) immediately after reperfusion showed an increase in the systolic blood velocity and urine output was not observed. Arterial anastomotic stenosis was suspected, but upon exploration, a renal artery dissection was detected in the middle portion of the donor artery. The part of the transplant renal artery was resected, and cold reflux was started again. At the resected part of transplant renal artery, dissection was identified. After re-anastomosis, Doppler US revealed that the blood flow of the renal artery was adequate without an increase in the systolic blood velocity, and sufficient blood flow was observed throughout the allograft. Urine output was also observed as soon as blood flow returned, and serum creatinine level decreased to 0.95 mg/dL after surgery. The cause of injury might have been vascular clamping in order to drain the air and check bleeding at the anastomosis. CONCLUSIONS:Our case reaffirmed that careful handling is needed in all procedures, including donor nephrectomy, cannulation for transplant perfusion, vascular clamping, and anastomosis, even without any evidence of arteriosclerosis. Kidney transplant recipients commonly have atherosclerosis and hypertension, which are risk factors for arterial dissection. Early diagnosis and intervention can lead to the prevention of allograft dysfunction. Therefore, close monitoring of allograft blood flow by Doppler US during surgery should be considered.
journal_name
BMC Nephroljournal_title
BMC nephrologyauthors
Hori S,Yoneda T,Tomizawa M,Ichikawa K,Morizawa Y,Nakai Y,Miyake M,Fujimoto Kdoi
10.1186/s12882-020-1699-xsubject
Has Abstractpub_date
2020-01-29 00:00:00pages
29issue
1issn
1471-2369pii
10.1186/s12882-020-1699-xjournal_volume
21pub_type
杂志文章相关文献
BMC Nephrology文献大全abstract:BACKGROUND:Asians have among the highest prevalence of chronic kidney disease (CKD) or end-stage renal disease in the world. A risk score capable of identifying high risk individuals at the primary care level could allow targeted therapy to prevent future development of CKD. Risk scores for new CKD have been developed ...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-017-0653-z
更新日期:2017-07-17 00:00:00
abstract:BACKGROUND:Kidney impairment constitutes severe risk for cardiovascular disease, stroke and all-cause mortality, and early identification and prevention of kidney impairment is critical to effective management of prognostic risk in community residents. Previous studies have validated that carotid-femoral pulse wave vel...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-018-0897-2
更新日期:2018-05-02 00:00:00
abstract:BACKGROUND:Proteinuria after kidney transplantation portends a worse graft survival. However the magnitude of proteinuria related to patient and graft survival and its correlation with donor and recipient characteristics are poorly explored. METHODS:This study investigated the impact of post transplant proteinuria in ...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-019-1635-0
更新日期:2019-12-02 00:00:00
abstract:BACKGROUND:The clinical consequences of starting chronic peritoneal dialysis (PD) after emergent dialysis via a temporary hemodialysis (HD) catheter has rarely been evaluated within a full spectrum of treated end-stage renal disease (ESRD). We investigated the longer-term outcomes of patients undergoing emergent-start ...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-017-0764-6
更新日期:2017-12-11 00:00:00
abstract:BACKGROUND:Association between metabolic syndrome (MS) and mildly reduced estimated glomerular filtration rates (eGFRs) remains unclear. Therefore, we aimed to evaluate the association between MS and a mildly reduced eGFR in Chinese adults. METHODS:Anthropometric and biochemical examinations were performed in 2992 ind...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-017-0597-3
更新日期:2017-06-13 00:00:00
abstract:BACKGROUND:Klotho is a transmembrane protein acting as a co-receptor for FGF-23 and thus exerts clinical actions on mineral metabolism. The association of secreted Klotho with outcomes in CKD patients is unclear. This study examined the relation between plasma Klotho and cardiovascular events in dialysis patients, acco...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-019-1391-1
更新日期:2019-06-11 00:00:00
abstract:BACKGROUND:Endothelial dysfunction occurs in patients with end-stage renal disease (ESRD) and is associated with increased cardiovascular morbidity and mortality. Asymmetric dimethylarginine (ADMA) contributes to endothelial dysfunction in ESRD. In the general population, angiotensin-converting enzyme (ACE) inhibitors ...
journal_title:BMC nephrology
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12882-015-0162-x
更新日期:2015-10-22 00:00:00
abstract:BACKGROUND:Corticosteroids are widely used to reduce the urine protein levels of patients with immunoglobulin A nephropathy (IgAN). However, their potential preventive effects on end-stage kidney disease (ESKD) are unclear. METHODS:We previously performed a large-scale, long-term multicenter cohort study of patients w...
journal_title:BMC nephrology
pub_type: 杂志文章,多中心研究
doi:10.1186/s12882-018-1019-x
更新日期:2018-09-06 00:00:00
abstract:BACKGROUND:The aim of the study was to assess the association between chronic kidney disease (CKD) and obesity in predicting CKD among Chinese adults, distinguishing between 5 different adiposity indices: visceral fat index (VFI), percentage body fat (PBF), body mass index (BMI), waist circumference (WC) and waist-to-h...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-018-0837-1
更新日期:2018-02-17 00:00:00
abstract:BACKGROUND:Metabolic acidosis leads to chronic kidney disease (CKD) progression. The guidelines recommend a lower limit of serum bicarbonate level, but no upper limit. For serum bicarbonate level to be clinically useful as a therapeutic target marker, it is necessary to investigate the target serum bicarbonate level wi...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/1471-2369-14-4
更新日期:2013-01-09 00:00:00
abstract:BACKGROUND:Inherited cystic kidney disease is a spectrum of disorders in which clusters of renal cysts develop as the result of genetic mutation. The exact methods and pipelines for defining genetic mutations of inherited cystic kidney disease are not clear at this point. This 3-year, prospective, multicenter, cohort s...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-020-02207-8
更新日期:2021-01-06 00:00:00
abstract:BACKGROUND:IgA nephropathy (IgAN) is the most common glomerulonephritis worldwide and is an important cause of end-stage renal disease (ESRD). Exploring novel biomarkers is necessary for predicting the disease activity and progression of IgAN patients. The present study sought to investigate the value of serum C4 for p...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-019-1420-0
更新日期:2019-07-04 00:00:00
abstract:BACKGROUND:Concentration of the urine is primarily regulated via vasopressin dependent aquaporin-2 water channels in the apical membrane of kidney principal cells. It is unclear whether urine concentration ability in ADPKD differs from other patients with similar degree of impaired renal function (non-ADPKD patients). ...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-020-02043-w
更新日期:2020-08-31 00:00:00
abstract:BACKGROUND:Autosomal dominant polycystic kidney disease (ADPKD) is one of the most common hereditary kidney diseases that frequently result in renal failure. In this cross-sectional observational cohort study, we evaluated urinary angiotensinogen (AGT) as a potential biomarker to assess renal function in ADPKD. METHOD...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-015-0075-8
更新日期:2015-06-20 00:00:00
abstract:BACKGROUND:In view of the prevalence of oxidative stress in chronic kidney disease (CKD) patients, the loss of low-molecular-weight biomolecules by hemodialysis and the antioxidant potential of some uremic solutes that accumulate in CKD, we used in vitro model systems to test the antioxidant potential of the following ...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-015-0029-1
更新日期:2015-04-11 00:00:00
abstract:BACKGROUND:Recipients of living donor renal transplantation are typically considered to have a relatively lower immunological risk. This retrospective study aimed to compare the therapeutic efficacy and safety between rabbit antithymocyte globulin (rATG) or interleukin-2 receptor antagonist (IL2-RA) induction therapies...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-019-1293-2
更新日期:2019-03-22 00:00:00
abstract:BACKGROUND:Glomerular filtration rate (GFR) is the best index of renal function, but age, gender and ethnicity can putatively affect its values. The aim of this study was to establish reference values for GFR in healthy Brazilian subjects while taking these factors into account. METHODS:In this cross-sectional study, ...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/1471-2369-14-54
更新日期:2013-02-28 00:00:00
abstract:BACKGROUND:The patterns, performance characteristics, and yield of diagnostic tests ordered for the evaluation of acute kidney injury (AKI) have not been rigorously evaluated. METHODS:We characterized the frequency of AKI diagnostic testing for urine, blood, radiology, and pathology tests in all adult inpatients who w...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-016-0224-8
更新日期:2016-01-15 00:00:00
abstract::Chronic kidney disease (CKD) is an inherently systemic disease that refers to a long-term loss of kidney function. The progression of CKD has repercussions for other organs, leading to many kinds of extrarenal complications. Intensive studies are now being undertaken to reveal the risk factors and pathophysiological m...
journal_title:BMC nephrology
pub_type: 杂志文章,评审
doi:10.1186/s12882-018-1094-z
更新日期:2018-10-22 00:00:00
abstract:BACKGROUND:Acute kidney injury (AKI) places a heavy burden on the healthcare system in China and is usually misdiagnosed. However, there are limited studies that have described the epidemiology and diagnosis of AKI in China. The aim of this study was to describe the incidence and diagnosis of AKI in hospitalized adult ...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-017-0622-6
更新日期:2017-06-24 00:00:00
abstract:BACKGROUND:Hypertension is a public health problem with mostly unknown causes, and where strong hereditary genetic alterations have not been fully elucidated. However, the use of experimental models has provided valuable information. Recent evidences suggest that alterations in key nephrogenic factors, such as Wilms' t...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-016-0250-6
更新日期:2016-03-24 00:00:00
abstract:BACKGROUND:Nephrotic syndrome (NS) is pathological condition characterized by heavy proteinuria. Our study investigates hypothesis that change in cell proliferation of proximal tubules influences primary cilia structure and function and promotes cystogenesis in congenital nephrotic syndrome of the Finnish type (CNF) an...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/1471-2369-15-3
更新日期:2014-01-08 00:00:00
abstract:BACKGROUND:In sub-Saharan Africa, chronic kidney disease (CKD) is being recognized as a non-communicable disease (NCD) with high morbidity and mortality. In countries like Tanzania, people access many sources, including traditional medicines, to meet their healthcare needs for NCDs, but little is known about traditiona...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-015-0161-y
更新日期:2015-10-23 00:00:00
abstract:BACKGROUND:Acute kidney injury (AKI) remains a frequent complication in children undergoing hematopoietic stem cell transplantation (HSCT) and an independent risk factor of the patient's survival and a prognostic factor of progression to chronic kidney disease (CKD). However, the causes of these complications are diver...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-020-02045-8
更新日期:2020-08-27 00:00:00
abstract:BACKGROUND:Patients who start renal replacement therapy (RRT) for End-Stage Kidney Disease (ESKD) without having had timely access to specialist renal services have poor outcomes. At one NHS Trust in England, a community-wide CKD management system has led to a decline in the incident rate of RRT and the lowest percenta...
journal_title:BMC nephrology
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12882-017-0522-9
更新日期:2017-04-11 00:00:00
abstract:BACKGROUND:It remained lack of a kind of contrast-induced acute kidney injury (CI-AKI) model which was widely used in clinical practice and comparable to CI-AKI in humans. METHODS:Fifty Sprague-Dawley rats were divided into five groups of 10 rats each: (1) sham group (normal saline [NS] + NS); (2) NS plus low osmolali...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-019-1436-5
更新日期:2019-07-04 00:00:00
abstract::This paper describes the 30-year experience on nutritional management of non-dialysis dependent chronic kidney disease (CKD) patients in a public outpatient clinic located in the city of São Paulo, Brazil. A team of specialized dietitians in renal nutrition is responsible to provide individual dietary counseling for p...
journal_title:BMC nephrology
pub_type: 信件
doi:10.1186/s12882-016-0282-y
更新日期:2016-07-16 00:00:00
abstract:BACKGROUND:Severe renal manifestation of systemic lupus erythematosus (SLE) is not uncommon and is associated with an indeterminate prognosis. Complete remission can be obtained, however, at least in the young when chronic lesions are absent and adequate anti-inflammatory therapy is immediately initiated. CASE PRESENT...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/1471-2369-13-81
更新日期:2012-08-06 00:00:00
abstract:BACKGROUND:Periodontal disease is associated with increased mortality in the general population, however its prognostic significance in chronic kidney disease (CKD) is not known. We evaluated the joint effect of periodontal disease and CKD on all-cause and cardiovascular mortality. METHODS:Prospective observational st...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-015-0101-x
更新日期:2015-07-07 00:00:00
abstract:BACKGROUND:Single nucleotide polymorphisms (SNPs) are the most common forms of sequence variations in the human genome. They contribute to the human phenotypic spectrum and are associated with variations in response to pathogens, drugs and vaccines. Recently, SNPs in three human genes involved in kidney development (RE...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/1471-2369-12-60
更新日期:2011-10-28 00:00:00