Gitelman-like syndrome after cisplatin therapy: a case report and literature review.

abstract：BACKGROUND:Chloride is speculated to have nephrotoxic properties. In healthy subjects we tested the hypothesis that acute chloride loading with 3% saline would induce kidney injury, which could be prevented with the loop-diuretic furosemide. METHODS:The study was designed as a randomized, placebo-controlled, crossover...

journal_title：BMC nephrology

authors： Mose FH,Jörgensen AN,Vrist MH,Ekelöf NP,Pedersen EB,Bech JN

更新日期：2019-06-03 00:00:00

abstract：BACKGROUND:Lupus nephritis (LN) is a severe consequence of systemic lupus erythematosus (SLE) that affects approximately 40% of patients. Pathogenic immune complexes that are characteristic of LN deposit in the kidney and activate immune mediated pathways including the complement system. Complete remission rates in LN ...

journal_title：BMC nephrology

authors： Wright RD,Bannerman F,Beresford MW,Oni L

更新日期：2020-06-30 00:00:00

abstract：BACKGROUND:Urinary Ca2+ excretion increases with dietary NaCl. NaCl-induced calciuria may be associated with hypertension, urinary stone formation and osteoporosis, but its mechanism and long-term effects are not fully understood. This study examined alterations in the expressions of renal Ca2+ transporters, channels a...

journal_title：BMC nephrology

authors： Yatabe MS,Yatabe J,Takano K,Murakami Y,Sakuta R,Abe S,Sanada H,Kimura J,Watanabe T

更新日期：2012-12-02 00:00:00

abstract：BACKGROUND:Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used and have been linked to acute kidney injury (AKI), chronic kidney disease (CKD) and cardiovascular disease (CVD). Patients who survive an AKI episode are at risk for future adverse kidney and cardiovascular outcomes. The objective of our study wa...

journal_title：BMC nephrology

authors： Lipworth L,Abdel-Kader K,Morse J,Stewart TG,Kabagambe EK,Parr SK,Birdwell KA,Matheny ME,Hung AM,Blot WJ,Ikizler TA,Siew ED

更新日期：2016-11-24 00:00:00

abstract：BACKGROUND:Echocardiographic characteristics across the spectrum of chronic kidney disease (CKD) have not been well described. We assessed the echocardiographic characteristics of patients with preserved renal function and mild or moderate CKD referred for echocardiography and determined whether echocardiographic param...

journal_title：BMC nephrology

authors： Mavrakanas TA,Khattak A,Singh K,Charytan DM

更新日期：2018-07-11 00:00:00

abstract：BACKGROUND:Observational studies have demonstrated an association between nephrolithiasis and hypertension. The aim of this meta-analysis was to summarize all available evidence. METHODS:PubMed, EMBASE, the Cochrane Central Register of Controlled Trials databases, and the reference lists of relevant articles were sear...

journal_title：BMC nephrology

authors： Shang W,Li Y,Ren Y,Yang Y,Li H,Dong J

更新日期：2017-11-29 00:00:00

abstract：BACKGROUND:End-stage kidney disease patients undergoing haemodialysis are prescribed with multiple complex regimens and are predisposed to high risk of medication nonadherence. The aims of this study were to explore factors associated with medication adherence, and, to examine the differential perspectives on medicatio...

journal_title：BMC nephrology

authors： Ghimire S,Castelino RL,Jose MD,Zaidi STR

更新日期：2017-05-22 00:00:00

abstract：BACKGROUND:Immunoglobulin light chains are classified as middle molecule uremic toxins able to interact with B lymphocyte membranes leading to the activation of transmembrane signaling. The ensuing impairment of neutrophil function can contribute to the chronic inflammation state of uremic patients, and the increased r...

journal_title：BMC nephrology

authors： Donati G,Moretti MI,Baraldi O,Spazzoli A,Capelli I,Comai G,Marchetti A,Sarma M,Mancini R,La Manna G

更新日期：2016-11-25 00:00:00

abstract：BACKGROUND:Hyperphosphatemia is associated with vascular calcification and bone mineral disorders and is a major concern among patients with chronic kidney disease (CKD). However, the relationship between hyperphosphatemia and renal outcome in non-CKD patients has not been studied. Furthermore, the clinical implication...

journal_title：BMC nephrology

authors： Moon H,Chin HJ,Na KY,Joo KW,Kim YS,Kim S,Han SS

更新日期：2019-09-18 00:00:00

abstract：:In a recent study published by the National Project Team on chronic kidney diseases of unknown origin in Sri Lanka, identified cadmium as a major risk factor but strong conclusions were not made as the identified environmental toxins were within the permissible levels.Sri Lankan food consumption pattern is different s...

journal_title：BMC nephrology

authors： Jayalal TB

更新日期：2015-12-23 00:00:00

abstract：BACKGROUND:Data on radial access (RA) as an independent risk factor for acute kidney injury (AKI) in myocardial infarction (MI) patients are conflicting. Our aim was to assess how RA influences the incidence of AKI in MI patients undergoing percutaneous coronary intervention (PCI). METHODS:Data from 3842 MI patients u...

journal_title：BMC nephrology

authors： Kanic V,Kompara G,Šuran D,Tapajner A,Naji FH,Sinkovic A

更新日期：2019-01-30 00:00:00

abstract：BACKGROUND:Accurately determining renal function is essential for clinical management of HIV patients. Classically, it has been evaluated by estimating glomerular filtration rate (eGFR) with the MDRD-equation, but today there is evidence that the new Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation ...

journal_title：BMC nephrology

authors： Cristelli MP,Cofán F,Rico N,Trullàs JC,Manzardo C,Agüero F,Bedini JL,Moreno A,Oppenheimer F,Miro JM,CKD-H. Clinic Investigators.

更新日期：2017-02-10 00:00:00

abstract：BACKGROUND:Membranous nephropathy (MN) has been recognized to occur in patients with human immunodeficiency virus (HIV) infection since the beginning of the HIV epidemic. The prevalence of phospholipase A2 receptor (PLA2R)-associated MN in this group has not been well studied. METHODS:We conducted a retrospective revi...

journal_title：BMC nephrology

authors： Charu V,Andeen N,Walavalkar V,Lapasia J,Kim JY,Lin A,Sibley R,Higgins J,Troxell M,Kambham N

更新日期：2020-09-18 00:00:00

abstract：BACKGROUND:The management of proliferative lupus nephritis (LN) comprises timely and coordinated immunosuppressive therapy. This study aimed to evaluate and compare the effectiveness and safety profile of low dose mycophenolate mofetil (MMF) and cyclophosphamide (CYC) in induction therapy of LN in Nepalese population. ...

journal_title：BMC nephrology

authors： Sedhain A,Hada R,Agrawal RK,Bhattarai GR,Baral A

更新日期：2018-07-11 00:00:00

abstract：BACKGROUND:Lower serum bicarbonate, mainly due to the modern Western-style diet, and renal hyperfiltration (RHF) are both independently associated with higher mortality in the general population with preserved renal function. The objective of this study was to evaluate the association between serum bicarbonate and RHF....

journal_title：BMC nephrology

authors： Park M,So R,Joo KW,Yoon HJ

更新日期：2016-01-06 00:00:00

abstract：BACKGROUND:Variants in CUBN, the gene encoding cubilin, a proximal tubular transport protein, have been associated with albuminuria and vitamin B12 (B12) deficiency. We hypothesized that low levels of B12 would be associated with albuminuria in a population-based cohort. METHODS:We analyzed participants from the Frami...

journal_title：BMC nephrology

authors： McMahon GM,Hwang SJ,Tanner RM,Jacques PF,Selhub J,Muntner P,Fox CS

更新日期：2015-02-02 00:00:00

abstract：BACKGROUND:Patients who start renal replacement therapy (RRT) for End-Stage Kidney Disease (ESKD) without having had timely access to specialist renal services have poor outcomes. At one NHS Trust in England, a community-wide CKD management system has led to a decline in the incident rate of RRT and the lowest percenta...

journal_title：BMC nephrology

authors： Gallagher H,Methven S,Casula A,Thomas N,Tomson CR,Caskey FJ,Rose T,Walters SJ,Kennedy D,Dawnay A,Cassidy M,Fluck R,Rayner HC,Nation M

更新日期：2017-04-11 00:00:00

abstract：BACKGROUND:Emerging evidence of psychosocial problems in CKD patients has led to an acceptance that a focus on the emotional wellbeing of the patient should be included in the provision of comprehensive CKD care. It is unclear if an increased attention for psychosocial needs in guidelines and policy documents has led t...

journal_title：BMC nephrology

authors： Seekles ML,Ormandy P,Coyne E

更新日期：2019-03-21 00:00:00

abstract：BACKGROUND:A previous cohort study indicated a significant association of lower baseline level of physical activity in hemodialysis patients with elevated risks of mortality. However, there have been no reports regarding the association between changes in physical activity over time and mortality in hemodialysis patien...

journal_title：BMC nephrology

authors： Shimoda T,Matsuzawa R,Yoneki K,Harada M,Watanabe T,Matsumoto M,Yoshida A,Takeuchi Y,Matsunaga A

更新日期：2017-05-08 00:00:00

abstract：BACKGROUND:Patients with end-stage renal disease (ESRD) under hemodialysis (HD) are at greater risks of infectious spondylitis (IS), but there is no reliable predictor that facilitate early detection of this relatively rare and insidious disease. METHODS:A retrospective review of the medical records from patients with...

journal_title：BMC nephrology

authors： Lu KL,Huang WH,Lu YA,Lin CY,Wu HH,Hsu CW,Weng CH,Wu CY,Wu IW,Wu MY,Yen TH,Yang HY

更新日期：2019-08-16 00:00:00

abstract：BACKGROUND:The burden of kidney diseases is reported to be higher in lower- and middle-income countries as compared to developed countries, and countries in sub-Saharan Africa are reported to be most affected. Health systems in most sub-Sahara African countries have limited capacity in the form of trained and skilled h...

journal_title：BMC nephrology

authors： Furia FF,Shoo J,Ruggajo PJ,Kilonzo K,Basu G,Yeates K,Varughese S,Svarstad E,Kisanga O

更新日期：2019-10-17 00:00:00

abstract：BACKGROUND:Patients with end-stage renal disease (ESRD) exhibit a premature aging phenotype of immune system, which is recently concerned as a significant factor for increased risk of various morbidities. Nevertheless, there are few dates explicating the relevancy of T cell senescence to mortality. In this study, we pr...

journal_title：BMC nephrology

authors： Xiang F,Chen R,Cao X,Shen B,Chen X,Ding X,Zou J

更新日期：2020-07-13 00:00:00

abstract：BACKGROUND:Annual decline in kidney function is a widely applied surrogate outcome of renal failure. It is important to understand the relationships between known risk factors and the annual decline in estimated glomerular filtration rate (eGFR) according to baseline age; however, these remain unclear. METHODS:A commu...

journal_title：BMC nephrology

authors： Toyama T,Kitagawa K,Oshima M,Kitajima S,Hara A,Iwata Y,Sakai N,Shimizu M,Hashiba A,Furuichi K,Wada T

更新日期：2020-11-13 00:00:00

abstract：BACKGROUND:About 1% of patients admitted to the Emergency Department (ED) have hypernatremia, a condition associated with a mortality rate of 20 to 60%. Management recommendations originate from intensive care unit studies, in which patients and medical diseases differ from those in ED. METHODS:We retrospectively stud...

journal_title：BMC nephrology

authors： Bataille S,Baralla C,Torro D,Buffat C,Berland Y,Alazia M,Loundou A,Michelet P,Vacher-Coponat H

更新日期：2014-02-21 00:00:00

abstract：BACKGROUND:Adult patients with minimal change nephrotic syndrome (MCNS) are often associated with acute kidney injury (AKI). To assess the mechanisms of AKI, we examined whether tubular cell injuries unique to MCNS patients exist. METHODS:We performed a retrospective analysis of clinical data and tubular cell changes ...

journal_title：BMC nephrology

authors： Fujigaki Y,Tamura Y,Nagura M,Arai S,Ota T,Shibata S,Kondo F,Yamaguchi Y,Uchida S

更新日期：2017-11-28 00:00:00

abstract：BACKGROUND:Providing patient-centered care needs in patients with chronic renal failure undergoing hemodialysis is important in inspiring their confidence to continue their treatment and promote their mental and social health. Therefore, recognizing the concept of care from the viewpoint of these patients can be helpfu...

journal_title：BMC nephrology

authors： Shahgholian N,Yousefi H

更新日期：2018-11-26 00:00:00

abstract：BACKGROUND:Anaemia is common in haemodialysis (HD) patients and associated with significant morbidity and mortality. Intravenous (IV) iron combined with erythropoiesis-stimulating agents (ESA) is the mainstay treatment of anaemia in these patients. The comparative efficacy and risk of adverse events with IV iron prepar...

journal_title：BMC nephrology

authors： Jesus-Silva JA,Lamplugh A,Dhada S,Burton JO,Bhandari S

更新日期：2020-06-03 00:00:00

abstract：:Attention has recently been focused on addressing the problem of acute kidney injury in both the developed and developing world. Little information is actually available on the incidence and management of AKI in low resource settings. Thus, the paper by Bagasha in the current issue of BMC Nephrology makes an important...

journal_title：BMC nephrology

authors： Anand S,Cruz DN,Finkelstein FO

更新日期：2015-01-16 00:00:00

abstract：BACKGROUND:Fabry disease (FD) is an X-linked lysosomal storage disorder caused by mutations of the GLA gene, followed by deficiency in α-galactosidase A (α-gal) activity. Nephrotic syndrome, as the renal phenotype of FD, is unusual. Here, we report the rare case of a patient with FD with nephrotic syndrome whose protei...

journal_title：BMC nephrology

authors： Fujisawa H,Nakayama Y,Nakao S,Yamamoto R,Kurokawa Y,Nakamura N,Nagata A,Tsukimura T,Togawa T,Sakuraba H,Fukami K

更新日期：2019-12-17 00:00:00

abstract：BACKGROUND:Serum phosphorus control is critical for chronic kidney disease (CKD) 5D patients. Currently, clinical profile for an oral phosphorus binder in the mainland Chinese population is not available. OBJECTIVE:To establish the efficacy, safety, and tolerability of lanthanum carbonate in CKD 5D patients. DESIGN:M...

journal_title：BMC nephrology

authors： Xu J,Zhang YX,Yu XQ,Liu ZH,Wang LN,Chen JH,Fan YP,Ni ZH,Wang M,Yuan FH,Ding GH,Chen XM,Zhang AP,Mei CL

更新日期：2013-02-04 00:00:00