Abstract:
BACKGROUND:The burden of kidney diseases is reported to be higher in lower- and middle-income countries as compared to developed countries, and countries in sub-Saharan Africa are reported to be most affected. Health systems in most sub-Sahara African countries have limited capacity in the form of trained and skilled health care providers, diagnostic support, equipment and policies to provide nephrology services. Several initiatives have been implemented to support establishment of these services. METHODS:This is a situation analysis to examine the nephrology services in Tanzania. It was conducted by interviewing key personnel in institutions providing nephrology services aiming at describing available services and international collaborators supporting nephrology services. RESULTS:Tanzania is a low-income country in Sub-Saharan Africa with a population of more than 55 million that has seen remarkable improvement in the provision of nephrology services and these include increase in the number of nephrologists to 14 in 2018 from one in 2006, increase in number of dialysis units from one unit (0.03 unit per million) before 2007 to 28 units (0.5 units per million) in 2018 and improved diagnostic services with introduction of nephropathology services. Government of Tanzania has been providing kidney transplantation services by funding referral of donor and recipients abroad and has now introduced local transplantation services in two hospitals. There have been strong international collaborators who have supported nephrology services and establishment of nephrology training in Tanzania. CONCLUSION:Tanzania has seen remarkable achievement in provision of nephrology services and provides an interesting model to be used in supporting nephrology services in low income countries.
journal_name
BMC Nephroljournal_title
BMC nephrologyauthors
Furia FF,Shoo J,Ruggajo PJ,Kilonzo K,Basu G,Yeates K,Varughese S,Svarstad E,Kisanga Odoi
10.1186/s12882-019-1568-7subject
Has Abstractpub_date
2019-10-17 00:00:00pages
378issue
1issn
1471-2369pii
10.1186/s12882-019-1568-7journal_volume
20pub_type
杂志文章相关文献
BMC Nephrology文献大全abstract:BACKGROUND:Chronic kidney disease (CKD) is increasing worldwide and early education to improve adherence to self-management is a key strategy to slow CKD progression. The use of the internet and mobile phone technologies (mHealth) to support patients is considered an effective tool in many other chronic disease populat...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-018-0830-8
更新日期:2018-02-02 00:00:00
abstract:BACKGROUND:To assess whether serum osteoprotegerin (OPG) and/or fetuin-A predict mortality and cardiovascular (CV) morbidity and mortality in hemodialysis patients. METHODS:Multicenter, observational, prospective study that included 220 hemodialysis patients followed up for up to 6 years. Serum OPG and fetuin-A levels...
journal_title:BMC nephrology
pub_type: 杂志文章,多中心研究
doi:10.1186/s12882-017-0701-8
更新日期:2017-09-07 00:00:00
abstract:BACKGROUND:Alport syndrome and ANCA-associated vasculitis are both rare diseases. The co-existence of these two conditions has never been reported. There is no obvious pathogenic link between these two glomerular diseases. The management of this case highlights the importance of a systematic approach when investigating...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-017-0527-4
更新日期:2017-03-29 00:00:00
abstract:BACKGROUND:The clinical outcomes of ST-segment elevation myocardial infarction (STEMI) are poor in patients with renal insufficiency. This study investigated changes in the likelihood that patients received optimal medical care throughout the entire process of myocardial infarction management, on the basis of their glo...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/1471-2369-13-110
更新日期:2012-09-11 00:00:00
abstract:BACKGROUND:Almost all cases of renal hydatid cysts need surgical intervention for treatment. We report a case of isolated renal hydatid cyst treated successfully only with medical therapy. CASE PRESENTATION:This case is a 79-year-old veterinarian presented with right flank pain, hydatiduria and positive echinococcus g...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-020-02064-5
更新日期:2020-10-08 00:00:00
abstract:BACKGROUND:Use of serum creatinine to estimate GFR may lead to underestimation of the association between self-reported frailty and kidney function. Our objectives were to evaluate the association of measured GFR (mGFR) with self-reported frailty among patients with CKD and to determine whether self-reported frailty wa...
journal_title:BMC nephrology
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1186/s12882-015-0202-6
更新日期:2015-12-09 00:00:00
abstract:BACKGROUND:Decreased heat shock protein 27 (HSP27) participates in many processes that are involved in cardiovascular (CV) disease. The objective of the study was to evaluate if HSP27 level was predictive of mortality as well as to evaluate factors associated with HSP27 level in a group of patients treated with HD. ME...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-018-1157-1
更新日期:2018-12-17 00:00:00
abstract:BACKGROUND:Galectin-9 (Gal-9) induces apoptosis in activated T helper 1 (TH1) cells as a ligand for T cell immunoglobulin mucin-3 (Tim-3). Gal-9 also inhibits the G1 phase cell cycle arrest and hypertrophy in db/db mice, the hallmark of early diabetic nephropathy, by reversing the high glucose-induced up-regulation of ...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/1471-2369-14-23
更新日期:2013-01-22 00:00:00
abstract:BACKGROUND:The product of the concentrations of urinary tissue inhibitor of metalloproteinases-2 and insulin-like growth factor binding protein-7 (urinary [TIMP-2] × [IGFBP-7]) has been suggested as biomarker for early detection of acute kidney injury (AKI) in various clinical settings. However, the performance of urin...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-019-1456-1
更新日期:2019-07-17 00:00:00
abstract:BACKGROUND:A large body mass index (BMI) has been considered as a relative contraindication for percutaneous catheter insertion, although this technique has many advantages. Up to now, there are few studies on peritoneal catheter placement and obesity. The aim of this study was to determine whether patients with large ...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-020-01850-5
更新日期:2020-05-25 00:00:00
abstract:BACKGROUND:Dialysis has long been a critical issue in the field of nephrology, though the burden this lifesaving technology places on society can be immense. Effectively increasing the health literacy of hemodialysis patients can be beneficial for their health outcomes and self-care abilities. Thus, the aims of this st...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-016-0266-y
更新日期:2016-05-31 00:00:00
abstract:BACKGROUND:Sepsis is a common syndrome in critically ill patients and easily leads to the occurrence of acute kidney injury (AKI), with high mortality rates. This study aimed to investigate the diagnostic value of urine soluble CD163 (sCD163) for identification of sepsis, severity of sepsis, and for secondary AKI, and ...
journal_title:BMC nephrology
pub_type: 临床试验,杂志文章
doi:10.1186/1471-2369-13-123
更新日期:2012-09-26 00:00:00
abstract:BACKGROUND:Dyspepsia is a common disorder in kidney transplant recipients, and the risk of post-transplant complications is increased in candidates with upper gastrointestinal disease. We evaluated gastrointestinal lesions of kidney transplant candidates on dialysis. METHODS:In this study, endoscopic and pathological ...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-020-02108-w
更新日期:2020-10-22 00:00:00
abstract:BACKGROUND:Obstetric-related acute kidney injury (AKI) is thought to be a key contributor to the overall burden of AKI in low resource settings, causing significant and preventable morbidity and mortality. However, epidemiological data to corroborate these hypotheses is sparse. This prospective observational study aims...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-018-0824-6
更新日期:2018-02-02 00:00:00
abstract:BACKGROUND:Podocyte apoptosis is a major mechanism that leads to proteinuria in many kidney diseases. However, the concert mechanisms that cause podocyte apoptosis in these kidney diseases are not fully understood. RhoA is one of Rho GTPases that has been well studied and plays a key role in regulating cytoskeletal arc...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-016-0287-6
更新日期:2016-07-07 00:00:00
abstract:BACKGROUND:Observational studies have demonstrated an association between nephrolithiasis and hypertension. The aim of this meta-analysis was to summarize all available evidence. METHODS:PubMed, EMBASE, the Cochrane Central Register of Controlled Trials databases, and the reference lists of relevant articles were sear...
journal_title:BMC nephrology
pub_type: 杂志文章,meta分析
doi:10.1186/s12882-017-0762-8
更新日期:2017-11-29 00:00:00
abstract:BACKGROUND:Autosomal dominant polycystic kidney disease (ADPKD) is a hereditary disease characterized by the presence of renal cysts. Over time the expanding cysts lead to progressive renal failure. The use of tolvaptan, a V2-receptor antagonist, was recently approved in ADPKD patients. It was demonstrated that tolvapt...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-019-1612-7
更新日期:2019-11-21 00:00:00
abstract:BACKGROUND:Patients with advanced chronic kidney disease (CKD) exhibit higher prevalence of coronary artery calcification (CaC) than general population. CaC has been proposed as a risk factor for mortality in end-stage CKD, but most studies in the field are based on short-term follow-up. METHODS:We conducted a cohort,...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-019-1367-1
更新日期:2019-05-28 00:00:00
abstract:BACKGROUND:End-stage kidney disease patients undergoing haemodialysis are prescribed with multiple complex regimens and are predisposed to high risk of medication nonadherence. The aims of this study were to explore factors associated with medication adherence, and, to examine the differential perspectives on medicatio...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-017-0583-9
更新日期:2017-05-22 00:00:00
abstract:BACKGROUND:Family members of patients with end stage renal disease were reported to have an increased prevalence of chronic kidney disease (CKD). However, studies differentiated genetic and non-genetic family members are limited. We sought to investigate the prevalence of CKD among fist-degree relatives and spouses of ...
journal_title:BMC nephrology
pub_type: 杂志文章,多中心研究
doi:10.1186/1471-2369-14-19
更新日期:2013-01-18 00:00:00
abstract:BACKGROUND:Metabolic syndrome (MetS) has been established as a risk for cardiovascular diseases and mortality in hemodialysis patients. Energy intake (EI) is an important nutritional therapy for preventing MetS. We examined the association of self-reported dietary EI with metabolic abnormalities and MetS among hemodial...
journal_title:BMC nephrology
pub_type: 杂志文章,多中心研究
doi:10.1186/s12882-018-1041-z
更新日期:2018-09-19 00:00:00
abstract:BACKGROUND:The Canadian Study of Prediction of Death, Dialysis and Interim Cardiovascular Events (CanPREDDICT) is a large, prospective, pan-Canadian, cohort study designed to improve our understanding of determinants of renal and cardiovascular (CV) disease progression in patients with chronic kidney disease (CKD). The...
journal_title:BMC nephrology
pub_type: 杂志文章,多中心研究
doi:10.1186/1471-2369-14-121
更新日期:2013-06-11 00:00:00
abstract:BACKGROUND:Diabetic nephropathy is a global common cause of chronic kidney disease and end-stage renal disease. A lot of research has been conducted in biomedical sciences, which has enhanced understanding of the pathophysiology of diabetic nephropathy and has expanded the potential available therapies. An increasing n...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-019-1590-9
更新日期:2019-10-28 00:00:00
abstract:BACKGROUND:Lupus nephritis (LN) is a severe consequence of systemic lupus erythematosus (SLE) that affects approximately 40% of patients. Pathogenic immune complexes that are characteristic of LN deposit in the kidney and activate immune mediated pathways including the complement system. Complete remission rates in LN ...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-020-01888-5
更新日期:2020-06-30 00:00:00
abstract:BACKGROUND:The use of metformin in patients with type 2 diabetes mellitus has been associated with lactic acidosis. However, the information available in patients with moderate-severe chronic kidney disease is scarce. METHODS:The ALIMAR-C2 study is a case-control study to assess the association between metformin and l...
journal_title:BMC nephrology
pub_type: 杂志文章,多中心研究
doi:10.1186/s12882-019-1389-8
更新日期:2019-05-30 00:00:00
abstract:BACKGROUND:Previous studies have not described the relationship between reducing radial artery diameter as well as increasing age and functional maturation of the radio-cephalic arteriovenous fistula (RCAVF) and no data identify these as linear relationship. The objective of this study was to perform trend analysis to ...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-020-01883-w
更新日期:2020-06-22 00:00:00
abstract:BACKGROUND:Autosomal dominant polycystic kidney disease (ADPKD) is one of the most common hereditary kidney diseases that frequently result in renal failure. In this cross-sectional observational cohort study, we evaluated urinary angiotensinogen (AGT) as a potential biomarker to assess renal function in ADPKD. METHOD...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-015-0075-8
更新日期:2015-06-20 00:00:00
abstract:BACKGROUND:Polycystic Kidney Disease (PKD) kidneys exhibit increased extracellular matrix (ECM) collagen expression and metalloproteinases (MMPs) activity. We investigated the role of these increases on cystic disease progression in PKD kidneys. METHODS:We examined the role of type I collagen (collagen I) and membrane...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/1471-2369-13-109
更新日期:2012-09-11 00:00:00
abstract:BACKGROUND:This retrospective study was undertaken to determine the incidence of kidney dysfunction (KD) and to identify potential risk factors contributing to development of KD in orthopaedic population following an elective or emergency surgery. METHODS:A total of 1025 patients were admitted in our institution over ...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/1471-2369-13-101
更新日期:2012-09-03 00:00:00
abstract:BACKGROUND:Haemodialysis is the most common form of renal replacement therapy in Nigeria. The high cost of haemodialysis has made optimal therapy of end-stage renal disease difficult in Nigeria. This paper is a review of data collected over two years of provision of dialysis services in a new tertiary hospital in South...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/1471-2369-12-50
更新日期:2011-10-02 00:00:00