Treatment with cinacalcet increases plasma sclerostin concentration in hemodialysis patients with secondary hyperparathyroidism.

abstract：BACKGROUND:End-stage kidney disease patients undergoing haemodialysis are prescribed with multiple complex regimens and are predisposed to high risk of medication nonadherence. The aims of this study were to explore factors associated with medication adherence, and, to examine the differential perspectives on medicatio...

journal_title：BMC nephrology

authors： Ghimire S,Castelino RL,Jose MD,Zaidi STR

更新日期：2017-05-22 00:00:00

abstract：INTRODUCTION:Urinary biomarkers of kidney injury are presumed to reflect renal tubular damage. However, their concentrations may be influenced by other factors, such as hematuria or pyuria. We sought to examine what non-injury related urinalysis factors are associated with urinary biomarker levels. METHODS:We examined...

journal_title：BMC nephrology

authors： Nadkarni GN,Coca SG,Meisner A,Patel S,Kerr KF,Patel UD,Koyner JL,Garg AX,Philbrook HT,Edelstein CL,Shlipak M,El-Khoury J,Parikh CR,TRIBE-AKI Consortium Investigators.

更新日期：2017-07-06 00:00:00

abstract：BACKGROUND:Calcific Uremic Arteriolopathy (CUA) is a rare disease, causing painful skin ulcers in patients with end stage renal disease. Recommendations for CUA management and treatment are lacking. METHODS:We conducted a retrospective cohort study on CUA cases identified in western France, in order to describe its ma...

journal_title：BMC nephrology

authors： Gaisne R,Péré M,Menoyo V,Hourmant M,Larmet-Burgeot D

更新日期：2020-02-26 00:00:00

abstract：BACKGROUND:Hypertensive nephropathy (HTN) is a kind of renal injury caused by chronic hypertension, which seriously affect people's life. The purpose of this study was to identify the potential biomarkers of HTN and understand its possible mechanisms. METHODS:The dataset numbered GSE28260 related to hypertensive and n...

journal_title：BMC nephrology

authors： Wang Z,Liu Z,Yang Y,Kang L

更新日期：2020-11-11 00:00:00

abstract：BACKGROUND:The possibility of clearing Cell-free Plasma Hemoglobin (CPH) from human plasma may appear attractive, especially when considering the noxious effects that CPH has on the immune function and the renal damage caused by its filtration. The existence of the so-called High Cut-Off (HCO) filters, possessing pores...

journal_title：BMC nephrology

authors： Cucchiari D,Reverter E,Blasco M,Molina-Andujar A,Carpio A,Sanz M,Escorsell A,Fernández J,Poch E

更新日期：2018-10-04 00:00:00

abstract：BACKGROUND:We sought to investigate the relationships among the plasma levels of carotenoids, tocopherols, endogenous antioxidants, oxidative damage and lipid profiles and their possible effects on the cardiovascular risk associated with hemodialysis (HD) patients. METHODS:The study groups were divided into HD and hea...

journal_title：BMC nephrology

authors： Roehrs M,Valentini J,Paniz C,Moro A,Charão M,Bulcão R,Freitas F,Brucker N,Duarte M,Leal M,Burg G,Grune T,Garcia SC

更新日期：2011-10-26 00:00:00

abstract：BACKGROUND:Age and number of recipients in need of kidney re-transplantation are increasing. Re-transplantation practices and outcomes in elderly recipients are not previously explored. We aimed to retrospectively evaluate the outcomes of recipients 65 years and older receiving their second deceased donor allograft. M...

journal_title：BMC nephrology

authors： Heldal K,Hartmann A,Lønning K,Leivestad T,Reisæter AV,Line PD,Holdaas H,Midtvedt K

更新日期：2017-01-11 00:00:00

abstract：BACKGROUND:Group A streptococcus (GAS) is an etiological agent for the immune mediated sequela post streptococcal glomerulonephritis (PSGN). In some populations PSGN is recognized as a risk factor for chronic kidney disease (CKD) and end-stage renal disease (ESRD). It was found that a significantly greater proportion o...

journal_title：BMC nephrology

authors： Karmarkar MG,Hule GP,Hase NK,Mehta PR,Walter SR,Sriprakash KS

更新日期：2013-05-06 00:00:00

abstract：BACKGROUND:Rehabilitation effects of exercise training on adults with chronic kidney disease (CKD) have been generally recognised; however, the effects of exercise training on proteinuria have been underexplored. Our aim was to explore the effects of exercise training on proteinuria in adult CKD patients without renal ...

journal_title：BMC nephrology

authors： Yang L,Wu X,Wang Y,Wang C,Hu R,Wu Y

更新日期：2020-05-11 00:00:00

abstract：BACKGROUND:Diabetic nephropathy (DN) is a primary complication of diabetes mellitus (DM). The pathology of DN is still vague, and diagnostic accuracy is not enough. This study was performed to identify miRNAs and genes that have possibilities of being used as therapeutic targets for DN in type 2 DM. METHODS:Human miRN...

journal_title：BMC nephrology

authors： Yu Y,Jia YY,Wang M,Mu L,Li HJ

更新日期：2021-01-12 00:00:00

abstract：BACKGROUND:The patterns, performance characteristics, and yield of diagnostic tests ordered for the evaluation of acute kidney injury (AKI) have not been rigorously evaluated. METHODS:We characterized the frequency of AKI diagnostic testing for urine, blood, radiology, and pathology tests in all adult inpatients who w...

journal_title：BMC nephrology

authors： Leaf DE,Srivastava A,Zeng X,McMahon GM,Croy HE,Mendu ML,Kachalia A,Waikar SS

更新日期：2016-01-15 00:00:00

abstract：BACKGROUND:Interleukin 17 is a proinflammatory cytokine involved in immune response after allograft transplantation. IL-17 family of proinflammatory cytokines includes IL-17A and IL-17F. Previous studies have demonstrated that the rs2275913 IL17A and the rs11465553 IL17F gene polymorphism are associated with kidney all...

journal_title：BMC nephrology

authors： Domanski L,Kłoda K,Patrzyk M,Wisniewska M,Safranow K,Sienko J,Sulikowski T,Staniszewska M,Pawlik A

更新日期：2019-04-08 00:00:00

abstract：BACKGROUND:Critically ill coronavirus disease 2019 (COVID-19) patients have a high risk of acute kidney injury (AKI) that requires renal replacement therapy (RRT). A state of hypercoagulability reduces circuit life spans. To maintain circuit patency and therapeutic efficiency, an optimized anticoagulation strategy is n...

journal_title：BMC nephrology

authors： Arnold F,Westermann L,Rieg S,Neumann-Haefelin E,Biever PM,Walz G,Kalbhenn J,Tanriver Y

更新日期：2020-11-16 00:00:00

abstract：BACKGROUND:Cardiovascular morbidity and mortality are highly prevalent in patients with end-stage renal disease, and osteoprotegerin (OPG) may be an important link between bone loss and vascular calcification. This study was conducted to evaluate the relationship between central arterial stiffness and serum OPG levels ...

journal_title：BMC nephrology

authors： Hou JS,Lin YL,Wang CH,Lai YH,Kuo CH,Subeq YM,Hsu BG

更新日期：2019-05-23 00:00:00

abstract：BACKGROUND:Liddle's syndrome is a rare monogenic form of hypertension caused by truncating or missense mutations in the C termini of the epithelial sodium channel (ENaC) β or γ subunits. Patients with this syndrome present with early onset of hypertension, hypokalemia, metabolic alkalosis, hyporeninemia and hypoaldoste...

journal_title：BMC nephrology

authors： Yamaguchi E,Yoshikawa K,Nakaya I,Kato K,Miyasato Y,Nakagawa T,Kakizoe Y,Mukoyama M,Soma J

更新日期：2018-05-23 00:00:00

abstract：BACKGROUND:Both dialysis facilities and hospitals are accountable for 30-day hospital readmissions among U.S. hemodialysis patients. We examined the association of post-hospitalization processes of care at hemodialysis facilities with pulmonary edema-related and other readmissions. METHODS:In a retrospective cohort co...

journal_title：BMC nephrology

authors： Plantinga LC,Masud T,Lea JP,Burkart JM,O'Donnell CM,Jaar BG

更新日期：2018-07-31 00:00:00

abstract：BACKGROUND:Almost all cases of renal hydatid cysts need surgical intervention for treatment. We report a case of isolated renal hydatid cyst treated successfully only with medical therapy. CASE PRESENTATION:This case is a 79-year-old veterinarian presented with right flank pain, hydatiduria and positive echinococcus g...

journal_title：BMC nephrology

authors： Moghtadaie A,Yazdi SAM,Mohraz M,Asefi H,Razeghi E

更新日期：2020-10-08 00:00:00

abstract：BACKGROUND:Chronic kidney disease (CKD) accelerates vascular stiffening related to age. Arterial stiffness may be evaluated measuring the carotid-femoral pulse wave velocity (PWV) or more simply, as recommended by KDOQI, monitoring pulse pressure (PP). Both correlate to survival and incidence of cardiovascular disease....

journal_title：BMC nephrology

authors： Salvadé I,Schätti-Stählin S,Violetti E,Schönholzer C,Cereghetti C,Zwahlen H,Berwert L,Burnier M,Gabutti L

更新日期：2015-04-23 00:00:00

abstract：BACKGROUND:Levetiracetam is a frequently used drug in the therapy of partial onset, myoclonic and generalized tonic-clonic seizures. The main route of elimination is via the kidneys, which eliminate 66% of the unchanged drug as well as 24% as inactive metabolite that stems from enzymatic hydrolysis. Therefore dose adju...

journal_title：BMC nephrology

authors： Bahte SK,Hiss M,Lichtinghagen R,Kielstein JT

更新日期：2014-04-16 00:00:00

abstract：BACKGROUND:The Reducing Disparities in Access to kidNey Transplantation Community Study (RaDIANT) was an End-Stage Renal Disease (ESRD) Network 6-developed, dialysis facility-level randomized trial testing the effectiveness of a 1-year multicomponent education and quality improvement intervention in increasing referral...

journal_title：BMC nephrology

authors： Hamoda RE,Gander JC,McPherson LJ,Arriola KJ,Cobb L,Pastan SO,Plantinga L,Browne T,Hartmann E,Mulloy L,Zayas C,Krisher J,Patzer RE

更新日期：2018-01-15 00:00:00

abstract：:In a recent study published by the National Project Team on chronic kidney diseases of unknown origin in Sri Lanka, identified cadmium as a major risk factor but strong conclusions were not made as the identified environmental toxins were within the permissible levels.Sri Lankan food consumption pattern is different s...

journal_title：BMC nephrology

authors： Jayalal TB

更新日期：2015-12-23 00:00:00

abstract：BACKGROUND:Decreased heat shock protein 27 (HSP27) participates in many processes that are involved in cardiovascular (CV) disease. The objective of the study was to evaluate if HSP27 level was predictive of mortality as well as to evaluate factors associated with HSP27 level in a group of patients treated with HD. ME...

journal_title：BMC nephrology

authors： Jaroszyński A,Jaroszyńska A,Zaborowski T,Drelich-Zbroja A,Zapolski T,Dąbrowski W

更新日期：2018-12-17 00:00:00

abstract：BACKGROUND:Glucocorticoids (GCs) are frequently used to treat glomerular diseases but are associated with multiple adverse effects including hypothalamic-pituitary-adrenal axis inhibition that can lead to adrenal insufficiency (AI) on withdrawal. There is no agreed GC tapering strategy to minimise this risk. METHODS:T...

journal_title：BMC nephrology

authors： Karangizi AHK,Al-Shaghana M,Logan S,Criseno S,Webster R,Boelaert K,Hewins P,Harper L

更新日期：2019-05-06 00:00:00

abstract：BACKGROUND:Autosomal dominant polycystic kidney disease (ADPKD) is the leading inheritable cause of end-stage renal disease (ESRD); however, the natural course of disease progression is heterogeneous between patients. This study aimed to develop a natural history model of ADPKD that predicted progression rates and long...

journal_title：BMC nephrology

authors： McEwan P,Bennett Wilton H,Ong ACM,Ørskov B,Sandford R,Scolari F,Cabrera MV,Walz G,O'Reilly K,Robinson P

更新日期：2018-02-13 00:00:00

abstract：BACKGROUND:The risk of an individual to develop an acute kidney injury (AKI), or its severity, cannot be reliably predicted by common clinical risk factors. Whether genetic risk factors have an explanatory role poses an interesting question, however. Thus, we conducted a systematic literature review regarding genetic p...

journal_title：BMC nephrology

authors： Vilander LM,Kaunisto MA,Pettilä V

更新日期：2015-12-02 00:00:00

abstract：BACKGROUND:Sepsis is a common syndrome in critically ill patients and easily leads to the occurrence of acute kidney injury (AKI), with high mortality rates. This study aimed to investigate the diagnostic value of urine soluble CD163 (sCD163) for identification of sepsis, severity of sepsis, and for secondary AKI, and ...

journal_title：BMC nephrology

authors： Su L,Feng L,Liu C,Jiang Z,Li M,Xiao K,Yan P,Jia Y,Feng D,Xie L

更新日期：2012-09-26 00:00:00

abstract：BACKGROUND:The product of the concentrations of urinary tissue inhibitor of metalloproteinases-2 and insulin-like growth factor binding protein-7 (urinary [TIMP-2] × [IGFBP-7]) has been suggested as biomarker for early detection of acute kidney injury (AKI) in various clinical settings. However, the performance of urin...

journal_title：BMC nephrology

authors： Schiefer J,Lichtenegger P,Berlakovich GA,Plöchl W,Krenn CG,Baron DM,Baron-Stefaniak J,Faybik P

更新日期：2019-07-17 00:00:00

abstract：BACKGROUND:Dementia is common in end-stage renal disease (ESRD) patients on hemodialysis (HD) and is associated with worse outcomes. This study aimed to investigate the risk of major adverse cardiac and cerebrovascular event (MACCE) in elderly patients with dementia initiating HD. METHODS:Using the database from the H...

journal_title：BMC nephrology

authors： Jung SM,Kim CT,Kang EW,Kim KH,Lee S,Oh HJ,Kim SJ,Kang DH,Choi KB,Ryu DR,Kim H

更新日期：2017-04-06 00:00:00

abstract：BACKGROUND:Approximately 4-6% of incident end stage renal disease (ESRD) patients in the U.S. recover enough kidney function to discontinue dialysis but there is considerable geographic variation. We undertook this study to investigate whether state-level variations in renal recovery among incident ESRD patients correl...

journal_title：BMC nephrology

authors： Chen Z,Lee BJ,McCulloch CE,Burrows NR,Heung M,Hsu RK,Pavkov ME,Powe NR,Saran R,Shahinian V,Hsu CY,Centers for Disease Control and Prevention Chronic Kidney Disease Surveillance Team.

更新日期：2019-09-02 00:00:00

abstract：BACKGROUND:Renal proximal tubular sodium and glucose reabsorption are regulated by the sodium-glucose cotransporter (SGLT2). Changes in this transporter can play a role in hyperglycaemia and reactive oxygen species (ROS) production. We demonstrated increased glucose absorption in proximal tubule membrane vesicles and i...

journal_title：BMC nephrology

authors： Reyes-Pardo H,Bautista R,Vargas-Robles H,Rios A,Sánchez D,Escalante B

更新日期：2019-08-02 00:00:00