Abstract:
BACKGROUND:Multiple factors influence timing of dialysis initiation. The impact of supply of nephrology workforce on timing and incidence of dialysis initiation is not well known. METHODS:We determined the number of pediatric and adult nephrologists in each state using data from the American Medical Association and American Boards of Internal Medicine and Pediatrics. We ascertained state population data from the 2010 US Census. United States Renal Data System (USRDS) data were used to determine estimated glomerular filtration rate (eGFR) at dialysis initiation and dialysis incidence for adults (≥18 years) in 2008 and children (<18 years) in 2007-2009 by state. RESULTS:Across all states, there were a median of 3.0 (IQR 2.3 to 3.4) adult nephrologists per 100,000 adults and 0.5 (IQR 0.2 to 0.9) pediatric nephrologists per 100,000 children. The median eGFR at start of dialysis was 9.8 mL/min/1.73 m2 (IQR 7.1-13.1) in adults and 8.5 mL/min/1.73 m2 (IQR 6.2-11.4) in children. Neither the number of adult (Spearman r of 0.02 [95% CI -0.26-0.30], p = 0.88) nor pediatric (Spearman r of -0.13 [95% -0.39-0.15], p = 0.38) nephrologists per state population was associated with mean eGFR across states. The number of nephrologists per state population was associated with incident dialysis cases per state population in adults (Spearman r of 0.50 [95% CI 0.26-0.68], p = 0.0002), but not in children (Spearman r of -0.06 [95% CI -0.33-0.22], p = 0.67). In linear regression models, the association between nephrologists per state population and incident dialysis cases per state population remained statistically significant (p = 0.006) after adjustment for provider characteristics. CONCLUSIONS:Nephrology workforce supply is aligned with demand but does not appear to be associated with timing of dialysis initiation.
journal_name
BMC Nephroljournal_title
BMC nephrologyauthors
Ku E,Johansen KL,Portale AA,Grimes B,Hsu CYdoi
10.1186/1471-2369-16-2subject
Has Abstractpub_date
2015-01-15 00:00:00pages
2issn
1471-2369pii
1471-2369-16-2journal_volume
16pub_type
杂志文章相关文献
BMC Nephrology文献大全abstract:BACKGROUND:The presence of glutathione transferase (GST) M1 null genotype (GSTM1-null) in end-stage renal disease (ESRD) patients is associated with lower overall survival rate in comparison to those with GSTM1-active variants. We examined association between GSTM1 and GSTT1 deletion polymorphisms as well as SNPs in GS...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/1471-2369-15-12
更新日期:2014-01-14 00:00:00
abstract:BACKGROUND:Despite lithium being the most efficacious treatment for bipolar disorder, its use has been decreasing at least in part due to concerns about its potential to cause significant nephrotoxicity. Whilst the ability of lithium to cause nephrogenic diabetes insipidus is well established, its ability to cause chro...
journal_title:BMC nephrology
pub_type: 杂志文章,评审
doi:10.1186/s12882-018-1101-4
更新日期:2018-11-03 00:00:00
abstract:BACKGROUND:Chronic kidney disease (CKD) is increasing worldwide and early education to improve adherence to self-management is a key strategy to slow CKD progression. The use of the internet and mobile phone technologies (mHealth) to support patients is considered an effective tool in many other chronic disease populat...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-018-0830-8
更新日期:2018-02-02 00:00:00
abstract:BACKGROUND:Current guidelines regarding plasma-sampling techniques for glomerular filtration rate (GFR) determination are inconsistent. Single-sample methods are commonly believed not to be precise enough to meet clinical demands. The present study compared the agreement between single- and dual- plasma sampling method...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-018-0965-7
更新日期:2018-07-11 00:00:00
abstract:BACKGROUND:MicroRNAs have been demonstrated to play an important role in the pathogenesis of diabetic nephropathy (DN). In this study, we investigated both the repertoire of miRNAs in the kidneys of patients with DN and their potential regulatory role in inflammation-mediated glomerular endothelial injury. METHODS:The...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/1471-2369-15-142
更新日期:2014-09-02 00:00:00
abstract:BACKGROUND:Bordetella pertussis infection is a known trigger of atypical hemolytic uremic syndrome (HUS). For patients suspected of having atypical HUS, prompt plasma exchange/infusion (PE/PI) or eculizumab (ECZ) treatment is recommended. CASE PRESENTATION:We report a 1-month-old female infant who was admitted with a ...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-018-1168-y
更新日期:2018-12-17 00:00:00
abstract:BACKGROUND:The short-term efficacy of tolvaptan in patients with autosomal dominant polycystic kidney disease (ADPKD) has been demonstrated across several phase 3 trials, while the ADPKD Outcomes Model (ADPKD-OM) represents a validated approach to predict natural disease progression over a lifetime horizon. This study ...
journal_title:BMC nephrology
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12882-019-1290-5
更新日期:2019-04-23 00:00:00
abstract:BACKGROUND:Very less is known about health-related quality of life (HRQOL) among patients with kidney diseases in Nepal. This study examined HRQOL among haemodialysis and kidney transplant recipients in Nepal. METHODS:The Nepali version of World Health Organization Quality of Life Instruments -(WHOQOL-BREF) questionna...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-020-02085-0
更新日期:2020-10-12 00:00:00
abstract:BACKGROUND:The optimal revascularization strategy for patients with impaired glomerular filtration rate (IGFR) has not been established in acute coronary syndrome (ACS). We investigated the prognosis and impact of IGFR and invasive strategy on the cardiovascular outcomes in the ACS population. METHODS:In a Taiwan nati...
journal_title:BMC nephrology
pub_type: 杂志文章,多中心研究
doi:10.1186/1471-2369-15-66
更新日期:2014-04-23 00:00:00
abstract:BACKGROUND:Chronic hepatitis B virus (HBV) infection and chronic kidney disease (CKD) have high prevalences in Taiwan and worldwide. However, the association of untreated chronic hepatitis B virus (HBV) infection with chronic kidney disease (CKD) remains unclear. METHODS:This cohort study used claims data in the Taiwa...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-015-0106-5
更新日期:2015-07-22 00:00:00
abstract:BACKGROUND:Inflammatory processes are very important in the development of kidney disease. Nevertheless, the association between white blood cell (WBC) count and the risk of renal dysfunction has not been well-established, especially in subjects without chronic kidney disease (CKD). Our study investigated the associati...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-017-0608-4
更新日期:2017-06-07 00:00:00
abstract:BACKGROUND:During continuous venovenous haemofiltration (CVVH), regional anticoagulation with citrate may be superior to heparin in terms of biocompatibility, since heparin as opposed to citrate may activate complement (reflected by circulating C5a) and induce neutrophil degranulation in the filter and myeloperoxidase ...
journal_title:BMC nephrology
pub_type: 杂志文章,随机对照试验
doi:10.1186/1471-2369-15-19
更新日期:2014-01-17 00:00:00
abstract:BACKGROUND:The first aim of the study was to investigate the accuracy and intra-laboratory variation of serum creatinine measurements in clinical laboratories in Flanders. The second purpose was to check the effect of this variation in serum creatinine concentration results on the calculated estimated glomerular filtra...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-015-0012-x
更新日期:2015-02-14 00:00:00
abstract:BACKGROUND:Residing remotely from health care resources appears to impact quality of care delivery. It remains unclear if there are differences in vascular access based on distance of one's residence to dialysis centre at time of dialysis initiation, and whether region or duration of pre-dialysis care are important eff...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/1471-2369-15-40
更新日期:2014-02-27 00:00:00
abstract:BACKGROUND:A classification tree model (CT-PIRP) was developed in 2013 to predict the annual renal function decline of patients with chronic kidney disease (CKD) participating in the PIRP (Progetto Insufficienza Renale Progressiva) project, which involves thirteen Nephrology Hospital Units in Emilia-Romagna (Italy). Th...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-019-1345-7
更新日期:2019-05-17 00:00:00
abstract:BACKGROUND:We hypothesized that the use of actual body weight might lead to more frequent misdiagnosis of acute kidney injury (AKI) than when ideal body weight is used in underweight and/or obese patients. We examined which definition of body weight is most effective in establishing a urinary diagnosis of AKI in septic...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-018-0895-4
更新日期:2018-05-02 00:00:00
abstract:BACKGROUND:Serum cystatin C (ScysC) may help predicting cardiovascular outcome not only through its ability to detect renal dysfunction but also through its potential connection to others factors that are directly related to cardiovascular diseases. We explored the potential association of ScysC with arterial stiffness...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/1471-2369-15-196
更新日期:2014-12-11 00:00:00
abstract:BACKGROUND:Lower serum bicarbonate, mainly due to the modern Western-style diet, and renal hyperfiltration (RHF) are both independently associated with higher mortality in the general population with preserved renal function. The objective of this study was to evaluate the association between serum bicarbonate and RHF....
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-015-0218-y
更新日期:2016-01-06 00:00:00
abstract:BACKGROUND:Diet can markedly affect acid-base status and it significantly influences chronic kidney disease (CKD) and its progression. The relationship of dietary acid load (DAL) and CKD has not been assessed on a population level. We examined the association of estimated net acid excretion (NAE(es)) with CKD; and soci...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/1471-2369-15-137
更新日期:2014-08-24 00:00:00
abstract:BACKGROUND:Aciduria caused by urinary excretion of acidic metabolic wastes produced in daily life is known to be augmented in patients with chronic kidney disease (CKD). To evaluate the reno-protective effect of oral alkalizing agents for the improvement of metabolic acidosis and neutralization of intratubular pH in th...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-020-01807-8
更新日期:2020-04-22 00:00:00
abstract:BACKGROUND:The management of proliferative lupus nephritis (LN) comprises timely and coordinated immunosuppressive therapy. This study aimed to evaluate and compare the effectiveness and safety profile of low dose mycophenolate mofetil (MMF) and cyclophosphamide (CYC) in induction therapy of LN in Nepalese population. ...
journal_title:BMC nephrology
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12882-018-0973-7
更新日期:2018-07-11 00:00:00
abstract:BACKGROUND:Self-management education needs have not been assessed in patients with complex co-morbid conditions such as diabetes and chronic kidney disease (CKD). The objectives of this study were to 1) determine the self-management education needs for patients with co-morbid diabetes and CKD and 2) co-develop an educa...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-019-1296-z
更新日期:2019-04-02 00:00:00
abstract:BACKGROUND:In patients treated by maintenance hemodialysis the relationship to survival of hemoglobin level and administered epoetin-alfa and intravenous iron is controversial. The study aim was to determine effects on patient survival of administered epoetin-alfa and intravenous iron, and of hemoglobin and variables r...
journal_title:BMC nephrology
pub_type: 杂志文章,多中心研究
doi:10.1186/1471-2369-10-6
更新日期:2009-02-26 00:00:00
abstract:BACKGROUND:Catalase is an important antioxidant enzyme that regulates the level of intracellular hydrogen peroxide and hydroxyl radicals. The effects of catalase deficiency on albuminuria and progressive glomerulosclerosis have not yet been fully elucidated. The adriamycin (ADR) nephropathy model is considered to be an...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/1471-2369-13-14
更新日期:2012-03-25 00:00:00
abstract:BACKGROUND:Sickle cell trait is not completely benign, and some renal complications can occur. The baseline rate of admission for gross hematuria in normal males carrying the sickle cell trait is 2%. CASE PRESENTATION:A 35-year-old non-smoking African man experienced a 2-week history of painless, profuse and persisten...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-018-0939-9
更新日期:2018-06-08 00:00:00
abstract:BACKGROUND:Chronic cyclosporine-(CsA)-mediated loss of kidney function is a major clinical problem in organ transplantation. We hypothesized that the mineralocorticoid receptor antagonist eplerenone (EPL) prevents chronic CsA-induced renal interstitial volume increase, tubule loss, and functional impairment in a rat mo...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/1471-2369-14-42
更新日期:2013-02-20 00:00:00
abstract:INTRODUCTION:Urinary biomarkers of kidney injury are presumed to reflect renal tubular damage. However, their concentrations may be influenced by other factors, such as hematuria or pyuria. We sought to examine what non-injury related urinalysis factors are associated with urinary biomarker levels. METHODS:We examined...
journal_title:BMC nephrology
pub_type: 杂志文章,多中心研究
doi:10.1186/s12882-017-0629-z
更新日期:2017-07-06 00:00:00
abstract:BACKGROUND:Dietary and lifestyle factors may play an important role in the increasing prevalence of nephrolithiasis. We aimed to review and quantify the associations between lifestyle factors and incident nephrolithiasis and suggest lifestyle changes for the primary prevention of nephrolithiasis. METHODS:PubMed, EMBAS...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-020-01925-3
更新日期:2020-07-11 00:00:00
abstract:BACKGROUND:Immunoglobulin light chains are classified as middle molecule uremic toxins able to interact with B lymphocyte membranes leading to the activation of transmembrane signaling. The ensuing impairment of neutrophil function can contribute to the chronic inflammation state of uremic patients, and the increased r...
journal_title:BMC nephrology
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12882-016-0405-5
更新日期:2016-11-25 00:00:00
abstract:BACKGROUND:Obstetric-related acute kidney injury (AKI) is thought to be a key contributor to the overall burden of AKI in low resource settings, causing significant and preventable morbidity and mortality. However, epidemiological data to corroborate these hypotheses is sparse. This prospective observational study aims...
journal_title:BMC nephrology
pub_type: 杂志文章
doi:10.1186/s12882-018-0824-6
更新日期:2018-02-02 00:00:00