Citrate confers less filter-induced complement activation and neutrophil degranulation than heparin when used for anticoagulation during continuous venovenous haemofiltration in critically ill patients.

abstract：BACKGROUND:Despite improvement in short-term outcome of kidney transplants, the long-term survival of kidney transplants has not changed over past decades. Kidney biopsy is the gold standard of transplant pathology but it's invasive. Quantification of transplant blood flow could provide a novel non-invasive method to e...

journal_title：BMC nephrology

authors： Päivärinta J,Oikonen V,Räisänen-Sokolowski A,Tolvanen T,Löyttyniemi E,Iida H,Nuutila P,Metsärinne K,Koivuviita N

更新日期：2019-11-27 00:00:00

abstract：BACKGROUND:The aim of this study was to investigate the characteristics and outcomes of patients receiving renal replacement therapy for end-stage kidney disease (ESKD) secondary to haemolytic uraemic syndrome (HUS). METHODS:The study included all patients with ESKD who commenced renal replacement therapy in Australia...

journal_title：BMC nephrology

authors： Tang W,Mohandas J,McDonald SP,Hawley CM,Badve SV,Boudville N,Brown FG,Clayton PA,Wiggins KJ,Bannister KM,Campbell SB,Johnson DW

更新日期：2012-12-03 00:00:00

abstract：BACKGROUND:Fibrillary glomerulonephritis (FGN) is distinguished from amyloidosis by thicker fibrils and the lack of staining with histochemical dyes typically reactive with amyloid. However, congophilic FGN has been proposed recently and adding laser microdissection followed by mass spectrometry (LMD/MS) to conventiona...

journal_title：BMC nephrology

authors： Adachi M,Kitamura M,Muta K,Maekawa A,Uramatsu T,Tadokoro M,Funakoshi S,Hisano S,Kuwahara N,Shimizu A,Mukae H,Nishino T

更新日期：2020-05-24 00:00:00

abstract：BACKGROUND:African Americans have an increased incidence and worse prognosis with chronic kidney disease (CKD--estimated glomerular filtration rate [eGFR] <60 ml/min/1.73 m2) than their counterparts of European-descent. Inflammation has been related to renal disease in non-Hispanic whites, but there are limited data on...

journal_title：BMC nephrology

authors： Fox ER,Benjamin EJ,Sarpong DF,Nagarajarao H,Taylor JK,Steffes MW,Salahudeen AK,Flessner MF,Akylbekova EL,Fox CS,Garrison RJ,Taylor HA Jr

更新日期：2010-01-15 00:00:00

abstract：BACKGROUND:Chronic kidney disease (CKD) is increasing worldwide and early education to improve adherence to self-management is a key strategy to slow CKD progression. The use of the internet and mobile phone technologies (mHealth) to support patients is considered an effective tool in many other chronic disease populat...

journal_title：BMC nephrology

authors： Bonner A,Gillespie K,Campbell KL,Corones-Watkins K,Hayes B,Harvie B,Kelly JT,Havas K

更新日期：2018-02-02 00:00:00

abstract：BACKGROUND:We hypothesized that the use of actual body weight might lead to more frequent misdiagnosis of acute kidney injury (AKI) than when ideal body weight is used in underweight and/or obese patients. We examined which definition of body weight is most effective in establishing a urinary diagnosis of AKI in septic...

journal_title：BMC nephrology

authors： Katayama S,Koyama K,Goto Y,Koinuma T,Tonai K,Shima J,Wada M,Nunomiya S

更新日期：2018-05-02 00:00:00

abstract：BACKGROUND:Chronic kidney disease (CKD) accelerates vascular stiffening related to age. Arterial stiffness may be evaluated measuring the carotid-femoral pulse wave velocity (PWV) or more simply, as recommended by KDOQI, monitoring pulse pressure (PP). Both correlate to survival and incidence of cardiovascular disease....

journal_title：BMC nephrology

authors： Salvadé I,Schätti-Stählin S,Violetti E,Schönholzer C,Cereghetti C,Zwahlen H,Berwert L,Burnier M,Gabutti L

更新日期：2015-04-23 00:00:00

abstract：BACKGROUND:Diabetes mellitus is the leading cause of end-stage renal disease (ESRD) globally. Diabetes and human immunodeficiency virus (HIV), both prevalent in South Africa, have not been reported as significant causes of ESRD. METHODS:We evaluated chronic kidney disease (CKD) and cardiovascular disease risk factors ...

journal_title：BMC nephrology

authors： Madala ND,Thusi GP,Assounga AG,Naicker S

更新日期：2014-04-14 00:00:00

abstract：BACKGROUND:Cancer-related thrombotic microangiopathy (CR-TMA) is a rare entity associated with a dismal prognosis. Usually, CR-TMA is associated with mucin-producing carcinomas among which stomach, breast, prostate, lung and pancreas tumours are the most frequent. CASES PRESENTATION:We describe for the first time thre...

journal_title：BMC nephrology

authors： de Nattes T,Moreau-Grangé L,Vezzosi D,Hadoux J,Hie M,Guerrot D,Grangé S

更新日期：2020-01-30 00:00:00

abstract：BACKGROUND:Hyperchloremia is common in critically ill septic patients. The impact of hyperchloremia on the incidence of acute kidney injury (AKI) is not well studied. We investigated the association between hyperchloremia and AKI within the first 72 h of intensive care unit (ICU) admission. METHODS:6490 ICU adult pati...

journal_title：BMC nephrology

authors： Yessayan L,Neyra JA,Canepa-Escaro F,Vasquez-Rios G,Heung M,Yee J,Acute Kidney Injury in Critical Illness Study Group.

更新日期：2017-12-02 00:00:00

abstract：BACKGROUND:Several equations have been developed to estimate glomerular filtration rate (eGFR). The common equations used were derived from populations predominantly comprised of Caucasians with chronic kidney disease (CKD). Some of the equations provide a correction factor for African-Americans due to their relatively...

journal_title：BMC nephrology

authors： Omuse G,Maina D,Mwangi J,Wambua C,Kanyua A,Kagotho E,Amayo A,Ojwang P,Erasmus R

更新日期：2017-12-20 00:00:00

abstract：BACKGROUND:Patients with an impaired renal function show a high incidence of bone and mineral disturbances. These 'chronic kidney disease - mineral and bone disorders' (CKD-MBD) range from high turnover osteoporosis to adynamic bone disease. Currently, the histomorphometric analysis of a bone biopsy taken from the ilia...

journal_title：BMC nephrology

authors： Hiller RG,Patecki M,Neunaber C,Reifenrath J,Kielstein JT,Kielstein H

更新日期：2017-04-13 00:00:00

abstract：BACKGROUND:Pyrrolidine dithiocarbamate (PDTC) reduces renal cyst growth in a rodent model of polycystic kidney disease (PKD) but the mechanism of action is not clear. Here, we investigated the hypothesis that PDTC reduces the proliferation of cystic epithelial cells in vitro in a nuclear factor (NF)-κB-dependent manner...

journal_title：BMC nephrology

authors： Ta MH,Liuwantara D,Rangan GK

更新日期：2015-12-15 00:00:00

abstract：BACKGROUND:FGF23 controls serum l,25(OH)2D3 levels and phosphate homeostasis. This study evaluates the effects of ferritin on intact PTH, FGF23, and l,25(OH)2D3 in patients with major thalassemia. It also evaluates FGF23 changes in patients with hypoparathyroidism to clarify the interaction between FGF23 and PTH in the...

journal_title：BMC nephrology

authors： Saki F,Salehifar A,Kassaee SR,Omrani GR

更新日期：2020-11-16 00:00:00

abstract：BACKGROUND:Non-tunneled (temporary) hemodialysis catheters (NTHCs) are the least-optimal initial vascular access for incident maintenance hemodialysis patients yet little is known about factors associated with NTHC use in this context. We sought to determine factors associated with NTHC use and examine regional and fac...

journal_title：BMC nephrology

authors： Clark EG,Akbari A,Hiebert B,Hiremath S,Komenda P,Lok CE,Moist LM,Schachter ME,Tangri N,Sood MM

更新日期：2016-02-27 00:00:00

abstract：BACKGROUND:Sclerostin is a paracrine acting factor, which is expressed in the osteocytes and articular chondrocytes. Sclerostin decreases the osteoblast-related bone formation through the inhibition of the Wnt/β-catenin pathway. Osteocytes also express the Calcium sensing receptor which is a target for cinacalcet. The ...

journal_title：BMC nephrology

authors： Kuczera P,Adamczak M,Więcek A

更新日期：2016-11-15 00:00:00

abstract：BACKGROUND:The clinical outcomes of ST-segment elevation myocardial infarction (STEMI) are poor in patients with renal insufficiency. This study investigated changes in the likelihood that patients received optimal medical care throughout the entire process of myocardial infarction management, on the basis of their glo...

journal_title：BMC nephrology

authors： Choi JS,Kim CS,Bae EH,Ma SK,Jeong MH,Kim YJ,Cho MC,Kim CJ,Kim SW

更新日期：2012-09-11 00:00:00

abstract：BACKGROUND:The aim of this study was to describe the findings of renal biopsies from a large nephrology center in Iasi, Romania, performed between 2005 and 2010. We compared these findings with our previous ones, from 1995 to 2004, as well as with similar reports. METHODS:We studied retrospectively 239 renal biopsies....

journal_title：BMC nephrology

authors： Volovăt C,Cãruntu I,Costin C,Stefan A,Popa R,Volovăt S,Siriopol D,Voroneanu L,Nistor I,Segall L,Covic A

更新日期：2013-07-15 00:00:00

abstract：INTRODUCTION:Urinary biomarkers of kidney injury are presumed to reflect renal tubular damage. However, their concentrations may be influenced by other factors, such as hematuria or pyuria. We sought to examine what non-injury related urinalysis factors are associated with urinary biomarker levels. METHODS:We examined...

journal_title：BMC nephrology

authors： Nadkarni GN,Coca SG,Meisner A,Patel S,Kerr KF,Patel UD,Koyner JL,Garg AX,Philbrook HT,Edelstein CL,Shlipak M,El-Khoury J,Parikh CR,TRIBE-AKI Consortium Investigators.

更新日期：2017-07-06 00:00:00

abstract：:Chronic kidney disease (CKD) is an inherently systemic disease that refers to a long-term loss of kidney function. The progression of CKD has repercussions for other organs, leading to many kinds of extrarenal complications. Intensive studies are now being undertaken to reveal the risk factors and pathophysiological m...

journal_title：BMC nephrology

authors： Zou D,Wu W,He Y,Ma S,Gao J

更新日期：2018-10-22 00:00:00

abstract：BACKGROUND:Complement activation plays a substantial role in the pathogenesis of primary membranous nephropathy (pMN). C5b-9, C3c, MBL, and factor B have been documented in the subepithelial immune deposits. However, the changing of complement activation products in circulation and urine is not clear. METHODS:We measu...

journal_title：BMC nephrology

authors： Zhang MF,Huang J,Zhang YM,Qu Z,Wang X,Wang F,Meng LQ,Cheng XY,Cui Z,Liu G,Zhao MH

更新日期：2019-08-09 00:00:00

abstract：BACKGROUND:Urinary albumin can be measured in 24 h or spot samples. The 24 h urinary albumin excretion rate is considered the gold standard, but is cumbersome to collect. Instead, often an overnight sample is collected, and adjusted for dilution. Proxies for 24 h excretion rate have been studied in diabetics, but seldo...

journal_title：BMC nephrology

authors： Fagerstrom P,Sallsten G,Akerstrom M,Haraldsson B,Barregard L

更新日期：2015-01-24 00:00:00

abstract：BACKGROUND:Anaemia of chronic kidney disease increases the risk of death and adverse events, but can be managed using erythropoiesis stimulating agents (ESAs). However, recent evidence suggests that targeting a higher haemoglobin concentration ([Hb]) increases mortality risk, and both higher [Hb] targets and ESA doses ...

journal_title：BMC nephrology

authors： McMahon LP,Cai MX,Baweja S,Holt SG,Kent AB,Perkovic V,Leikis MJ,Becker GJ

更新日期：2012-06-15 00:00:00

abstract：:In a recent study published by the National Project Team on chronic kidney diseases of unknown origin in Sri Lanka, identified cadmium as a major risk factor but strong conclusions were not made as the identified environmental toxins were within the permissible levels.Sri Lankan food consumption pattern is different s...

journal_title：BMC nephrology

authors： Jayalal TB

更新日期：2015-12-23 00:00:00

abstract：BACKGROUND:The prevalence of chronic kidney disease (CKD) is increasing worldwide and in Africa. Health related quality of life (QOL) has become an essential outcome measure for patients with CKD and end stage renal disease (ESRD). There is growing interest worldwide in QOL of CKD patients but paucity of data in Ghana....

journal_title：BMC nephrology

authors： Tannor EK,Norman BR,Adusei KK,Sarfo FS,Davids MR,Bedu-Addo G

更新日期：2019-04-08 00:00:00

abstract：BACKGROUND:Association between metabolic syndrome (MS) and mildly reduced estimated glomerular filtration rates (eGFRs) remains unclear. Therefore, we aimed to evaluate the association between MS and a mildly reduced eGFR in Chinese adults. METHODS:Anthropometric and biochemical examinations were performed in 2992 ind...

journal_title：BMC nephrology

authors： Hu W,Wu XJ,Ni YJ,Hao HR,Yu WN,Zhou HW

更新日期：2017-06-13 00:00:00

abstract：BACKGROUND:Thermometers that measure core (internal) body temperature are the gold standard for monitoring temperature. Despite that most modern hemodialysis machines are equipped with an internal blood monitor that measures core body temperature, current practice is to use peripheral thermometers. A better understandi...

journal_title：BMC nephrology

authors： Lunney M,Tonelli B,Lewis R,Wiebe N,Thomas C,MacRae J,Tonelli M

更新日期：2018-06-14 00:00:00

abstract：BACKGROUND:Membranous nephropathy (MN) has been recognized to occur in patients with human immunodeficiency virus (HIV) infection since the beginning of the HIV epidemic. The prevalence of phospholipase A2 receptor (PLA2R)-associated MN in this group has not been well studied. METHODS:We conducted a retrospective revi...

journal_title：BMC nephrology

authors： Charu V,Andeen N,Walavalkar V,Lapasia J,Kim JY,Lin A,Sibley R,Higgins J,Troxell M,Kambham N

更新日期：2020-09-18 00:00:00

abstract：BACKGROUND:Lower serum bicarbonate, mainly due to the modern Western-style diet, and renal hyperfiltration (RHF) are both independently associated with higher mortality in the general population with preserved renal function. The objective of this study was to evaluate the association between serum bicarbonate and RHF....

journal_title：BMC nephrology

authors： Park M,So R,Joo KW,Yoon HJ

更新日期：2016-01-06 00:00:00

abstract：BACKGROUND:The presence of glutathione transferase (GST) M1 null genotype (GSTM1-null) in end-stage renal disease (ESRD) patients is associated with lower overall survival rate in comparison to those with GSTM1-active variants. We examined association between GSTM1 and GSTT1 deletion polymorphisms as well as SNPs in GS...

journal_title：BMC nephrology

authors： Suvakov S,Damjanovic T,Pekmezovic T,Jakovljevic J,Savic-Radojevic A,Pljesa-Ercegovac M,Radovanovic S,Simic DV,Pljesa S,Zarkovic M,Mimic-Oka J,Dimkovic N,Simic T

更新日期：2014-01-14 00:00:00