Red urine, updated for the nephrologist: a case report.

Abstract:

BACKGROUND:Sickle cell trait is not completely benign, and some renal complications can occur. The baseline rate of admission for gross hematuria in normal males carrying the sickle cell trait is 2%. CASE PRESENTATION:A 35-year-old non-smoking African man experienced a 2-week history of painless, profuse and persistent gross hematuria. Laboratory tests showed normal renal function, hematuria and mild proteinuria. Abdominal ultrasonography and computed tomography angiography revealed no renal abnormalities; the bladder appeared pristine under cystoscopy. The diagnosis of sickle cell trait associated with gross hematuria was made using hemoglobin electrophoresis; renal biopsy and its complications were avoided. Urine was clear after 2 weeks of oral hydration and gamma epsilon-aminocaproic acid. CONCLUSION:Hemoglobin electrophoresis should be performed in cases of gross hematuria. Coupled with other non-invasive evaluation, this could avoid renal biopsy and its associated complications.

journal_name

BMC Nephrol

journal_title

BMC nephrology

authors

Le Joncour A,Mesnard L,Hertig A,Robert T

doi

10.1186/s12882-018-0939-9

subject

Has Abstract

pub_date

2018-06-08 00:00:00

pages

133

issue

1

issn

1471-2369

pii

10.1186/s12882-018-0939-9

journal_volume

19

pub_type

杂志文章
  • 13-year nationwide cohort study of chronic kidney disease risk among treatment-naïve patients with chronic hepatitis B in Taiwan.

    abstract:BACKGROUND:Chronic hepatitis B virus (HBV) infection and chronic kidney disease (CKD) have high prevalences in Taiwan and worldwide. However, the association of untreated chronic hepatitis B virus (HBV) infection with chronic kidney disease (CKD) remains unclear. METHODS:This cohort study used claims data in the Taiwa...

    journal_title:BMC nephrology

    pub_type: 杂志文章

    doi:10.1186/s12882-015-0106-5

    authors: Chen YC,Su YC,Li CY,Hung SK

    更新日期:2015-07-22 00:00:00

  • Low birth weight associates with glomerular area in young male IgA nephropathy patients.

    abstract:BACKGROUND:In a recent study we demonstrated that low birth weight (LBW) was associated with increased risk of progressive IgA nephropathy (IgAN). In the present study we investigate whether this could be explained by differences in glomerular morphological parameters. METHODS:The Medical Birth Registry of Norway has ...

    journal_title:BMC nephrology

    pub_type: 杂志文章

    doi:10.1186/s12882-018-1070-7

    authors: Ruggajo P,Leh S,Svarstad E,Marti HP,Vikse BE

    更新日期:2018-10-22 00:00:00

  • Impaired renal function impacts negatively on vascular stiffness in patients with coronary artery disease.

    abstract:BACKGROUND:Chronic kidney disease (CKD) and coronary artery disease (CAD) are independently associated with increased vascular stiffness. We examined whether renal function contributes to vascular stiffness independently of CAD status. METHODS:We studied 160 patients with CAD and 169 subjects without CAD. The 4-variab...

    journal_title:BMC nephrology

    pub_type: 杂志文章

    doi:10.1186/1471-2369-14-173

    authors: Rossi SH,McQuarrie EP,Miller WH,Mackenzie RM,Dymott JA,Moreno MU,Taurino C,Miller AM,Neisius U,Berg GA,Valuckiene Z,Hannay JA,Dominiczak AF,Delles C

    更新日期:2013-08-13 00:00:00

  • Designing a web-application to support home-based care of childhood CKD stages 3-5: qualitative study of family and professional preferences.

    abstract:BACKGROUND:There is a lack of online, evidence-based information and resources to support home-based care of childhood CKD stages 3-5. METHODS:Qualitative interviews were undertaken with parents, patients and professionals to explore their views on content of the proposed online parent information and support (OPIS) w...

    journal_title:BMC nephrology

    pub_type: 杂志文章

    doi:10.1186/1471-2369-15-34

    authors: Swallow VM,Hall AG,Carolan I,Santacroce S,Webb NJ,Smith T,Hanif N

    更新日期:2014-02-18 00:00:00

  • Depression does not predict clinical outcome of Chinese peritoneal Dialysis patients after adjusting for the degree of frailty.

    abstract:BACKGROUND:Depression and frailty contribute to the adverse clinical outcome of peritoneal dialysis (PD) patients. However, the interaction between depression and frailty in PD patients remains uncertain. We determined the prevalence of depression and frailty in prevalent Chinese PD patients, dissected the internal rel...

    journal_title:BMC nephrology

    pub_type: 杂志文章

    doi:10.1186/s12882-020-01994-4

    authors: Chan GC,Ng JK,Chow KM,Kwan BC,Kwong VW,Pang WF,Cheng PM,Law MC,Leung CB,Li PK,Szeto CC

    更新日期:2020-08-05 00:00:00

  • Hepatitis B virus infection and development of chronic kidney disease: a cohort study.

    abstract:BACKGROUND:The effect of chronic hepatitis B virus (HBV) infection on the risk of chronic kidney disease (CKD) is controversial. We examined the prospective association between hepatitis B surface antigen (HBsAg) serology status and incident CKD in a large cohort of men and women. METHODS:Cohort study of 299,913 adult...

    journal_title:BMC nephrology

    pub_type: 杂志文章

    doi:10.1186/s12882-018-1154-4

    authors: Hong YS,Ryu S,Chang Y,Caínzos-Achirica M,Kwon MJ,Zhao D,Shafi T,Lazo M,Pastor-Barriuso R,Shin H,Cho J,Guallar E

    更新日期:2018-12-11 00:00:00

  • A novel model of reno-cardiac syndrome in the C57BL/ 6 mouse strain.

    abstract:BACKGROUND:The end stage renal disease population has a 20 fold higher incidence of cardiovascular mortality compared to the overall population. The development of reno-cardiac syndrome in these patients will result in cardiovascular events to be the cause of 50% of fatalities. There is therefore a need to research imp...

    journal_title:BMC nephrology

    pub_type: 杂志文章

    doi:10.1186/s12882-018-1155-3

    authors: Kieswich JE,Chen J,Alliouachene S,Caton PW,McCafferty K,Thiemermann C,Yaqoob MM

    更新日期:2018-12-04 00:00:00

  • Renal arteriography with endovascular ultrasound for the management of renal infarction patients.

    abstract:BACKGROUND:Renal infarction (RI) is a rare disease with poor prognosis. Appropriate secondary prevention treatment is essential and requires an exhaustive etiological assessment. We aimed to determine whether invasive endovascular explorations may improve the diagnostic process and change the secondary prevention treat...

    journal_title:BMC nephrology

    pub_type: 杂志文章

    doi:10.1186/s12882-020-01929-z

    authors: Ivanes F,Dewaele J,Touboul C,Gatault P,Sautenet B,Barbet C,Büchler M,Quilliet L,Angoulvant D,Halimi JM

    更新日期:2020-07-14 00:00:00

  • Is combined peritoneal dialysis and hemodialysis redundant? A nationwide study from Taiwan.

    abstract:BACKGROUND:Combined peritoneal dialysis (PD) and hemodialysis (HD) therapy (combined therapy) has numerous clinical benefits and should be emphasized for PD patients encountering technique failure. METHODS:This 12-year nationwide retrospective study was conducted to compare long-term outcomes (including admission and ...

    journal_title:BMC nephrology

    pub_type: 杂志文章

    doi:10.1186/s12882-020-01989-1

    authors: Chung MC,Yu TM,Wu MJ,Chuang YW,Muo CH,Chen CH,Chang CH,Shieh JJ,Hung PH,Chen JW,Chung CJ

    更新日期:2020-08-15 00:00:00

  • The mineralocorticoid receptor antagonist eplerenone reduces renal interstitial fibrosis after long-term cyclosporine treatment in rat: antagonizing cyclosporine nephrotoxicity.

    abstract:BACKGROUND:Chronic cyclosporine-(CsA)-mediated loss of kidney function is a major clinical problem in organ transplantation. We hypothesized that the mineralocorticoid receptor antagonist eplerenone (EPL) prevents chronic CsA-induced renal interstitial volume increase, tubule loss, and functional impairment in a rat mo...

    journal_title:BMC nephrology

    pub_type: 杂志文章

    doi:10.1186/1471-2369-14-42

    authors: Nielsen FT,Jensen BL,Hansen PB,Marcussen N,Bie P

    更新日期:2013-02-20 00:00:00

  • Diagnostic value of urine sCD163 levels for sepsis and relevant acute kidney injury: a prospective study.

    abstract:BACKGROUND:Sepsis is a common syndrome in critically ill patients and easily leads to the occurrence of acute kidney injury (AKI), with high mortality rates. This study aimed to investigate the diagnostic value of urine soluble CD163 (sCD163) for identification of sepsis, severity of sepsis, and for secondary AKI, and ...

    journal_title:BMC nephrology

    pub_type: 临床试验,杂志文章

    doi:10.1186/1471-2369-13-123

    authors: Su L,Feng L,Liu C,Jiang Z,Li M,Xiao K,Yan P,Jia Y,Feng D,Xie L

    更新日期:2012-09-26 00:00:00

  • Unexpected recovery from longterm renal failure in severe diffuse proliferative lupus nephritis.

    abstract:BACKGROUND:Severe renal manifestation of systemic lupus erythematosus (SLE) is not uncommon and is associated with an indeterminate prognosis. Complete remission can be obtained, however, at least in the young when chronic lesions are absent and adequate anti-inflammatory therapy is immediately initiated. CASE PRESENT...

    journal_title:BMC nephrology

    pub_type: 杂志文章

    doi:10.1186/1471-2369-13-81

    authors: Ross S,Benz K,Sauerstein K,Amann K,Dötsch J,Dittrich K

    更新日期:2012-08-06 00:00:00

  • The elevated levels of urinary angiotensinogen are correlated with the severity of idiopathic membranous nephropathy.

    abstract:BACKGROUND:Immunosuppressive treatment will predispose an idiopathic membranous nephropathy (iMN) patient to opportunistic infections. Disease severity is one of the main concerns for making the treatment decision. Urinary angiotensinogen (UAGT) level has been shown highly correlated with intrarenal renin-angiotensin s...

    journal_title:BMC nephrology

    pub_type: 杂志文章

    doi:10.1186/s12882-018-1165-1

    authors: Tang Z,Wang Y,Tao L,Guo Y,Zheng Y,Zheng D

    更新日期:2018-12-12 00:00:00

  • Beyond dialysis decisions: a qualitative exploration of decision-making among culturally and linguistically diverse adults with chronic kidney disease on haemodialysis.

    abstract:BACKGROUND:To date, limited research has been dedicated to exploring the experience of decision-making for chronic kidney disease (CKD) patients who have initiated dialysis and have to make decisions in the context of managing multiple illnesses. Evidence about the experience of decision-making for minority or disadvan...

    journal_title:BMC nephrology

    pub_type: 杂志文章,多中心研究

    doi:10.1186/s12882-018-1131-y

    authors: Muscat DM,Kanagaratnam R,Shepherd HL,Sud K,McCaffery K,Webster A

    更新日期:2018-11-27 00:00:00

  • Premature aging of circulating T cells predicts all-cause mortality in hemodialysis patients.

    abstract:BACKGROUND:Patients with end-stage renal disease (ESRD) exhibit a premature aging phenotype of immune system, which is recently concerned as a significant factor for increased risk of various morbidities. Nevertheless, there are few dates explicating the relevancy of T cell senescence to mortality. In this study, we pr...

    journal_title:BMC nephrology

    pub_type: 杂志文章

    doi:10.1186/s12882-020-01920-8

    authors: Xiang F,Chen R,Cao X,Shen B,Chen X,Ding X,Zou J

    更新日期:2020-07-13 00:00:00

  • Acute kidney injury in patients with myocardial infarction undergoing percutaneous coronary intervention using radial versus femoral access.

    abstract:BACKGROUND:Data on radial access (RA) as an independent risk factor for acute kidney injury (AKI) in myocardial infarction (MI) patients are conflicting. Our aim was to assess how RA influences the incidence of AKI in MI patients undergoing percutaneous coronary intervention (PCI). METHODS:Data from 3842 MI patients u...

    journal_title:BMC nephrology

    pub_type: 杂志文章

    doi:10.1186/s12882-019-1210-8

    authors: Kanic V,Kompara G,Šuran D,Tapajner A,Naji FH,Sinkovic A

    更新日期:2019-01-30 00:00:00

  • Interventional study to improve adherence to phosphate binder treatment in dialysis patients.

    abstract:BACKGROUND:Adherence to phosphate binder treatment is important to prevent high serum phosphate level in chronic dialysis patients. We therefore wanted to investigate patient knowledge, beliefs about and adherence to phosphate binders among these patients and assess whether one-to-one pharmacist-led education and couns...

    journal_title:BMC nephrology

    pub_type: 临床试验,杂志文章

    doi:10.1186/s12882-019-1334-x

    authors: Hjemås BJ,Bøvre K,Mathiesen L,Lindstrøm JC,Bjerknes K

    更新日期:2019-05-17 00:00:00

  • Risk factors and outcomes of acute kidney injury in South African critically ill adults: a prospective cohort study.

    abstract:BACKGROUND:There is a marked paucity of data concerning AKI in Sub-Saharan Africa, where there is a substantial burden of trauma and HIV. METHODS:Prospective data was collected on all patients admitted to a multi-disciplinary ICU in South Africa during 2017. Development of AKI (before or during ICU admission) was reco...

    journal_title:BMC nephrology

    pub_type: 杂志文章

    doi:10.1186/s12882-019-1620-7

    authors: Aylward RE,van der Merwe E,Pazi S,van Niekerk M,Ensor J,Baker D,Freercks RJ

    更新日期:2019-12-10 00:00:00

  • Nephrolithiasis and risk of hypertension: a meta-analysis of observational studies.

    abstract:BACKGROUND:Observational studies have demonstrated an association between nephrolithiasis and hypertension. The aim of this meta-analysis was to summarize all available evidence. METHODS:PubMed, EMBASE, the Cochrane Central Register of Controlled Trials databases, and the reference lists of relevant articles were sear...

    journal_title:BMC nephrology

    pub_type: 杂志文章,meta分析

    doi:10.1186/s12882-017-0762-8

    authors: Shang W,Li Y,Ren Y,Yang Y,Li H,Dong J

    更新日期:2017-11-29 00:00:00

  • Arg913Gln variation of SLC12A3 gene is associated with diabetic nephropathy in type 2 diabetes and Gitelman syndrome: a systematic review.

    abstract:BACKGROUND:Diabetic nephropathy is a global common cause of chronic kidney disease and end-stage renal disease. A lot of research has been conducted in biomedical sciences, which has enhanced understanding of the pathophysiology of diabetic nephropathy and has expanded the potential available therapies. An increasing n...

    journal_title:BMC nephrology

    pub_type: 杂志文章

    doi:10.1186/s12882-019-1590-9

    authors: De la Cruz-Cano E,Jiménez-González CDC,Morales-García V,Pineda-Pérez C,Tejas-Juárez JG,Rendón-Gandarilla FJ,Jiménez-Morales S,Díaz-Gandarilla JA

    更新日期:2019-10-28 00:00:00

  • Anti-neutrophil extracellular trap antibody in a patient with relapse of anti-neutrophil cytoplasmic antibody-associated vasculitis: a case report.

    abstract:BACKGROUND:Neutrophil extracellular traps (NETs) are web-like DNA decorated with antimicrobial proteins, such as myeloperoxidase (MPO), which are extruded from activated neutrophils. Although NETs are essential in innate immunity, an excessive formation of NETs has adverse effects, e.g., induction of anti-neutrophil cy...

    journal_title:BMC nephrology

    pub_type: 杂志文章

    doi:10.1186/s12882-018-0953-y

    authors: Shida H,Hashimoto N,Kusunoki Y,Hattanda F,Ogawa Y,Hayashi T,Nakazawa D,Masuda S,Tomaru U,Ishizu A

    更新日期:2018-06-22 00:00:00

  • Health related quality of life among haemodialysis and kidney transplant recipients from Nepal: a cross sectional study using WHOQOL-BREF.

    abstract:BACKGROUND:Very less is known about health-related quality of life (HRQOL) among patients with kidney diseases in Nepal. This study examined HRQOL among haemodialysis and kidney transplant recipients in Nepal. METHODS:The Nepali version of World Health Organization Quality of Life Instruments -(WHOQOL-BREF) questionna...

    journal_title:BMC nephrology

    pub_type: 杂志文章

    doi:10.1186/s12882-020-02085-0

    authors: Ranabhat K,Khanal P,Mishra SR,Khanal A,Tripathi S,Sigdel MR

    更新日期:2020-10-12 00:00:00

  • IL17A and IL17F genes polymorphisms are associated with histopathological changes in transplanted kidney.

    abstract:BACKGROUND:Interleukin 17 is a proinflammatory cytokine involved in immune response after allograft transplantation. IL-17 family of proinflammatory cytokines includes IL-17A and IL-17F. Previous studies have demonstrated that the rs2275913 IL17A and the rs11465553 IL17F gene polymorphism are associated with kidney all...

    journal_title:BMC nephrology

    pub_type: 杂志文章

    doi:10.1186/s12882-019-1308-z

    authors: Domanski L,Kłoda K,Patrzyk M,Wisniewska M,Safranow K,Sienko J,Sulikowski T,Staniszewska M,Pawlik A

    更新日期:2019-04-08 00:00:00

  • Liddle's-like syndrome associated with nephrotic syndrome secondary to membranous nephropathy: the first case report.

    abstract:BACKGROUND:Liddle's syndrome is a rare monogenic form of hypertension caused by truncating or missense mutations in the C termini of the epithelial sodium channel (ENaC) β or γ subunits. Patients with this syndrome present with early onset of hypertension, hypokalemia, metabolic alkalosis, hyporeninemia and hypoaldoste...

    journal_title:BMC nephrology

    pub_type: 杂志文章

    doi:10.1186/s12882-018-0916-3

    authors: Yamaguchi E,Yoshikawa K,Nakaya I,Kato K,Miyasato Y,Nakagawa T,Kakizoe Y,Mukoyama M,Soma J

    更新日期:2018-05-23 00:00:00

  • Effects of exercise training on proteinuria in adult patients with chronic kidney disease: a systematic review and meta-analysis.

    abstract:BACKGROUND:Rehabilitation effects of exercise training on adults with chronic kidney disease (CKD) have been generally recognised; however, the effects of exercise training on proteinuria have been underexplored. Our aim was to explore the effects of exercise training on proteinuria in adult CKD patients without renal ...

    journal_title:BMC nephrology

    pub_type: 杂志文章

    doi:10.1186/s12882-020-01816-7

    authors: Yang L,Wu X,Wang Y,Wang C,Hu R,Wu Y

    更新日期:2020-05-11 00:00:00

  • Perspectives and experiences of patients and healthcare professionals with geriatric assessment in chronic kidney disease: a qualitative study.

    abstract:BACKGROUND:Older patients with end-stage kidney disease (ESKD) often live with unidentified frailty and multimorbidity. Despite guideline recommendations, geriatric assessment is not part of standard clinical care, resulting in a missed opportunity to enhance (clinical) outcomes including quality of life in these patie...

    journal_title:BMC nephrology

    pub_type: 杂志文章

    doi:10.1186/s12882-020-02206-9

    authors: Voorend CGN,Berkhout-Byrne NC,Meuleman Y,Mooijaart SP,Bos WJW,van Buren M

    更新日期:2021-01-06 00:00:00

  • Effects of pyrrolidine dithiocarbamate on proliferation and nuclear factor-κB activity in autosomal dominant polycystic kidney disease cells.

    abstract:BACKGROUND:Pyrrolidine dithiocarbamate (PDTC) reduces renal cyst growth in a rodent model of polycystic kidney disease (PKD) but the mechanism of action is not clear. Here, we investigated the hypothesis that PDTC reduces the proliferation of cystic epithelial cells in vitro in a nuclear factor (NF)-κB-dependent manner...

    journal_title:BMC nephrology

    pub_type: 杂志文章

    doi:10.1186/s12882-015-0193-3

    authors: Ta MH,Liuwantara D,Rangan GK

    更新日期:2015-12-15 00:00:00

  • Effect of treatment on urinary kidney injury molecule-1 in IgA nephropathy.

    abstract:BACKGROUND:Kidney injury molecule-1 (KIM-1) is a biomarker useful for detecting early tubular damage and has been recently reported as a useful marker for evaluating kidney injury in IgA nephropathy (IgAN). We therefore investigated whether treatment decreases urinary KIM-1 excretion in IgAN. METHODS:We prospectively ...

    journal_title:BMC nephrology

    pub_type: 杂志文章

    doi:10.1186/1471-2369-14-139

    authors: Seo MS,Park MY,Choi SJ,Jeon JS,Noh H,Kim JK,Han DC,Hwang SD,Jin SY,Kwon SH

    更新日期:2013-07-09 00:00:00

  • Study protocol: a pilot study to determine the safety and efficacy of induction-therapy, de novo MPA and delayed mTOR-inhibition in liver transplant recipients with impaired renal function. PATRON-study.

    abstract:BACKGROUND:Patients undergoing liver transplantation with preexisting renal dysfunction are prone to further renal impairment with the early postoperative use of Calcineurin-inhibitors. However, there is only little scientific evidence for the safety and efficacy of de novo CNI free "bottom-up" regimens in patients wit...

    journal_title:BMC nephrology

    pub_type: 临床试验,杂志文章

    doi:10.1186/1471-2369-11-24

    authors: Schnitzbauer AA,Scherer MN,Rochon J,Sothmann J,Farkas SA,Loss M,Geissler EK,Obed A,Schlitt HJ

    更新日期:2010-09-14 00:00:00

  • Independent risk factors and long-term outcomes for acute kidney injury in pediatric patients undergoing hematopoietic stem cell transplantation: a retrospective cohort study.

    abstract:BACKGROUND:Acute kidney injury (AKI) remains a frequent complication in children undergoing hematopoietic stem cell transplantation (HSCT) and an independent risk factor of the patient's survival and a prognostic factor of progression to chronic kidney disease (CKD). However, the causes of these complications are diver...

    journal_title:BMC nephrology

    pub_type: 杂志文章

    doi:10.1186/s12882-020-02045-8

    authors: Hirano D,Kakegawa D,Miwa S,Umeda C,Takemasa Y,Tokunaga A,Kawakami Y,Ito A

    更新日期:2020-08-27 00:00:00