Expression of brain-derived neurotrophic factor in kidneys from normal and cyclosporine-treated rats.

abstract：BACKGROUND:Inflammatory processes are very important in the development of kidney disease. Nevertheless, the association between white blood cell (WBC) count and the risk of renal dysfunction has not been well-established, especially in subjects without chronic kidney disease (CKD). Our study investigated the associati...

journal_title：BMC nephrology

authors： Fan F,Jia J,Li J,Huo Y,Zhang Y

更新日期：2017-06-07 00:00:00

abstract：BACKGROUND:Complementary and Alternative Medicines (CAMs) are increasingly practiced in the general population; it is estimated that over 30% of patients with chronic diseases use CAMs on a regular basis. CAMs are also used in hospital settings, suggesting a growing interest in individualized therapies. One potential f...

journal_title：BMC nephrology

authors： Ferraresi M,Clari R,Moro I,Banino E,Boero E,Crosio A,Dayne R,Rosset L,Scarpa A,Serra E,Surace A,Testore A,Colombi N,Piccoli BG

更新日期：2013-06-21 00:00:00

abstract：BACKGROUND:The aims of this study are to find the prevalence of potential drug-drug interactions (DDIs) in patients with Hemodialysis and identify factors associated with these interactions if present. METHODS:The study was an observational- retrospective cohort study that was conducted in ten hemodialysis units in th...

journal_title：BMC nephrology

authors： Al-Ramahi R,Raddad AR,Rashed AO,Bsharat A,Abu-Ghazaleh D,Yasin E,Shehab O

更新日期：2016-07-26 00:00:00

abstract：BACKGROUND:Neutrophil extracellular traps (NETs) are web-like DNA decorated with antimicrobial proteins, such as myeloperoxidase (MPO), which are extruded from activated neutrophils. Although NETs are essential in innate immunity, an excessive formation of NETs has adverse effects, e.g., induction of anti-neutrophil cy...

journal_title：BMC nephrology

authors： Shida H,Hashimoto N,Kusunoki Y,Hattanda F,Ogawa Y,Hayashi T,Nakazawa D,Masuda S,Tomaru U,Ishizu A

更新日期：2018-06-22 00:00:00

abstract：BACKGROUND:Emerging evidence of psychosocial problems in CKD patients has led to an acceptance that a focus on the emotional wellbeing of the patient should be included in the provision of comprehensive CKD care. It is unclear if an increased attention for psychosocial needs in guidelines and policy documents has led t...

journal_title：BMC nephrology

authors： Seekles ML,Ormandy P,Coyne E

更新日期：2019-03-21 00:00:00

abstract：BACKGROUND:Hyperchloremia is common in critically ill septic patients. The impact of hyperchloremia on the incidence of acute kidney injury (AKI) is not well studied. We investigated the association between hyperchloremia and AKI within the first 72 h of intensive care unit (ICU) admission. METHODS:6490 ICU adult pati...

journal_title：BMC nephrology

authors： Yessayan L,Neyra JA,Canepa-Escaro F,Vasquez-Rios G,Heung M,Yee J,Acute Kidney Injury in Critical Illness Study Group.

更新日期：2017-12-02 00:00:00

abstract：BACKGROUND:Single nucleotide polymorphisms (SNPs) are the most common forms of sequence variations in the human genome. They contribute to the human phenotypic spectrum and are associated with variations in response to pathogens, drugs and vaccines. Recently, SNPs in three human genes involved in kidney development (RE...

journal_title：BMC nephrology

authors： Raghavendra A,Siji A,Sridhar TS,Phadke K,Vasudevan A

更新日期：2011-10-28 00:00:00

abstract：BACKGROUND:The effect of chronic hepatitis B virus (HBV) infection on the risk of chronic kidney disease (CKD) is controversial. We examined the prospective association between hepatitis B surface antigen (HBsAg) serology status and incident CKD in a large cohort of men and women. METHODS:Cohort study of 299,913 adult...

journal_title：BMC nephrology

authors： Hong YS,Ryu S,Chang Y,Caínzos-Achirica M,Kwon MJ,Zhao D,Shafi T,Lazo M,Pastor-Barriuso R,Shin H,Cho J,Guallar E

更新日期：2018-12-11 00:00:00

abstract：BACKGROUND:This is the first study that has examined non-cardiac incidental findings in research cardiac computed tomography (CT) of hemodialysis patients and their relationship with patient characteristics. METHODS:We performed a cross-sectional analysis in the Predictors of Arrhythmic and Cardiovascular Events in En...

journal_title：BMC nephrology

authors： Jaar BG,Zhang L,Chembrovich SV,Sozio SM,Shafi T,Scialla JJ,Tomaselli GF,Lima JA,Kao WH,Parekh RS,Meoni LA

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Atypical hemolytic uremic syndrome (aHUS) is a rare, genetically-mediated systemic disease most often caused by chronic, uncontrolled complement activation that leads to systemic thrombotic microangiopathy (TMA) and renal and other end-organ damage. METHODS:The global aHUS Registry, initiated in April 2012,...

journal_title：BMC nephrology

authors： Licht C,Ardissino G,Ariceta G,Cohen D,Cole JA,Gasteyger C,Greenbaum LA,Johnson S,Ogawa M,Schaefer F,Vande Walle J,Frémeaux-Bacchi V

更新日期：2015-12-10 00:00:00

abstract：BACKGROUND:Estimates of the incidence of glomerulonephritis (GN) and end-stage renal disease (ESRD) in an Iraqi population are compared with the United States (US) and Jordan. METHODS:The study set consist of renal biopsies performed in 2012 and 2013 in the Kurdish provinces of Northern Iraq. The age specific and age ...

journal_title：BMC nephrology

authors： Ali AA,Sharif DA,Almukhtar SE,Abd KH,Saleem ZSM,Hughson MD

更新日期：2018-10-11 00:00:00

abstract：BACKGROUND:Immunoglobulin light chains are classified as middle molecule uremic toxins able to interact with B lymphocyte membranes leading to the activation of transmembrane signaling. The ensuing impairment of neutrophil function can contribute to the chronic inflammation state of uremic patients, and the increased r...

journal_title：BMC nephrology

authors： Donati G,Moretti MI,Baraldi O,Spazzoli A,Capelli I,Comai G,Marchetti A,Sarma M,Mancini R,La Manna G

更新日期：2016-11-25 00:00:00

abstract：BACKGROUND:Observational studies have demonstrated an association between nephrolithiasis and hypertension. The aim of this meta-analysis was to summarize all available evidence. METHODS:PubMed, EMBASE, the Cochrane Central Register of Controlled Trials databases, and the reference lists of relevant articles were sear...

journal_title：BMC nephrology

authors： Shang W,Li Y,Ren Y,Yang Y,Li H,Dong J

更新日期：2017-11-29 00:00:00

abstract：BACKGROUND:Dietary and lifestyle factors may play an important role in the increasing prevalence of nephrolithiasis. We aimed to review and quantify the associations between lifestyle factors and incident nephrolithiasis and suggest lifestyle changes for the primary prevention of nephrolithiasis. METHODS:PubMed, EMBAS...

journal_title：BMC nephrology

authors： Lin BB,Lin ME,Huang RH,Hong YK,Lin BL,He XJ

更新日期：2020-07-11 00:00:00

abstract：BACKGROUND:In a previous study we showed that troponin I (TnI) > 0.42 ng/mL predicted the need of dialysis in a group of 29 septic patients admitted to the intensive care unit (ICU). We aimed to confirm such finding in a larger independent sample. METHODS:All septic patients admitted to an ICU from March 2016 to Febru...

journal_title：BMC nephrology

authors： de Almeida Thiengo D,Strogoff-de-Matos JP,Lugon JR,Graciano ML

更新日期：2018-11-20 00:00:00

abstract：BACKGROUND:In a recent study we demonstrated that low birth weight (LBW) was associated with increased risk of progressive IgA nephropathy (IgAN). In the present study we investigate whether this could be explained by differences in glomerular morphological parameters. METHODS:The Medical Birth Registry of Norway has ...

journal_title：BMC nephrology

authors： Ruggajo P,Leh S,Svarstad E,Marti HP,Vikse BE

更新日期：2018-10-22 00:00:00

abstract：BACKGROUND:Renal proximal tubular sodium and glucose reabsorption are regulated by the sodium-glucose cotransporter (SGLT2). Changes in this transporter can play a role in hyperglycaemia and reactive oxygen species (ROS) production. We demonstrated increased glucose absorption in proximal tubule membrane vesicles and i...

journal_title：BMC nephrology

authors： Reyes-Pardo H,Bautista R,Vargas-Robles H,Rios A,Sánchez D,Escalante B

更新日期：2019-08-02 00:00:00

abstract：BACKGROUND:Anaemia of chronic kidney disease increases the risk of death and adverse events, but can be managed using erythropoiesis stimulating agents (ESAs). However, recent evidence suggests that targeting a higher haemoglobin concentration ([Hb]) increases mortality risk, and both higher [Hb] targets and ESA doses ...

journal_title：BMC nephrology

authors： McMahon LP,Cai MX,Baweja S,Holt SG,Kent AB,Perkovic V,Leikis MJ,Becker GJ

更新日期：2012-06-15 00:00:00

abstract：BACKGROUND:Gitelman syndrome (GS) is an autosomal recessive inherited salt-losing tubulopathy (SLT). Here, we describe, for the first time, a case of GS without Gitelman-like features and with concomitant kidney stones, cysts and diabetic nephropathy (DN). CASE PRESENTATION:We described a male patient had a 19-year hi...

journal_title：BMC nephrology

authors： Chen Q,Wang X,Min J,Wang L,Mou L

更新日期：2021-01-07 00:00:00

abstract：BACKGROUND:People with end stage renal disease (ESRD) face important health-related decisions concerning end-of-life care and the use of life-support technologies. While people often want to be involved in making decisions about their health, there are many challenges. People with advanced illness may have limited or w...

journal_title：BMC nephrology

authors： Kapell Brown C,Kryworuchko J,Martin W

更新日期：2018-09-12 00:00:00

abstract：BACKGROUND:This study aimed to examine the relationship between 25-hyfromxyvitamin D (25OHD) and chronic kidney disease (CKD) incidence. METHODS:All the elderly who had participated both in the 2011-2012 survey and 2014 survey in the Chinese Longitudinal Healthy Longevity Survey (CLHLS), and have biomarker data were i...

journal_title：BMC nephrology

authors： Liu M,Wang J,He Y

更新日期：2019-01-15 00:00:00

abstract：BACKGROUND:Different measures of non-adherence to immunosuppressant (IS) medication have been found to be associated with rejection episodes after successful transplantation. The aim of the current study was to investigate whether graft rejection after renal transplantation is associated with patient-reported IS medica...

journal_title：BMC nephrology

authors： Scheel J,Reber S,Stoessel L,Waldmann E,Jank S,Eckardt KU,Grundmann F,Vitinius F,de Zwaan M,Bertram A,Erim Y

更新日期：2017-03-29 00:00:00

abstract：BACKGROUND:Acute kidney injury (AKI) is a serious clinical problem with high rate of mortality and morbidity. Currently used prophylactic and therapeutic strategies to address AKI are limited and warrant further studies. In the present study an attempt was made to investigate the effect of quinacrine, a phospholipase A...

journal_title：BMC nephrology

authors： Al Asmari AK,Al Sadoon KT,Obaid AA,Yesunayagam D,Tariq M

更新日期：2017-01-28 00:00:00

abstract：BACKGROUND:Accurately determining renal function is essential for clinical management of HIV patients. Classically, it has been evaluated by estimating glomerular filtration rate (eGFR) with the MDRD-equation, but today there is evidence that the new Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation ...

journal_title：BMC nephrology

authors： Cristelli MP,Cofán F,Rico N,Trullàs JC,Manzardo C,Agüero F,Bedini JL,Moreno A,Oppenheimer F,Miro JM,CKD-H. Clinic Investigators.

更新日期：2017-02-10 00:00:00

abstract：BACKGROUND:Protein-bound uremic toxins are associated with poor outcomes in patients with chronic kidney disease. The aim of this study is to investigate the relationship between indoxyl sulfate (IS), a protein-bound solute, and 90-day mortality in patients with acute kidney injury. METHODS:Adults with hospital-acquir...

journal_title：BMC nephrology

authors： Wang W,Hao G,Pan Y,Ma S,Yang T,Shi P,Zhu Q,Xie Y,Ma S,Zhang Q,Ruan H,Ding F

更新日期：2019-02-14 00:00:00

abstract：BACKGROUND:Both dialysis facilities and hospitals are accountable for 30-day hospital readmissions among U.S. hemodialysis patients. We examined the association of post-hospitalization processes of care at hemodialysis facilities with pulmonary edema-related and other readmissions. METHODS:In a retrospective cohort co...

journal_title：BMC nephrology

authors： Plantinga LC,Masud T,Lea JP,Burkart JM,O'Donnell CM,Jaar BG

更新日期：2018-07-31 00:00:00

abstract：BACKGROUND:The burden of kidney diseases is reported to be higher in lower- and middle-income countries as compared to developed countries, and countries in sub-Saharan Africa are reported to be most affected. Health systems in most sub-Sahara African countries have limited capacity in the form of trained and skilled h...

journal_title：BMC nephrology

authors： Furia FF,Shoo J,Ruggajo PJ,Kilonzo K,Basu G,Yeates K,Varughese S,Svarstad E,Kisanga O

更新日期：2019-10-17 00:00:00

abstract：BACKGROUND:Renal infarction (RI) is a rare disease with poor prognosis. Appropriate secondary prevention treatment is essential and requires an exhaustive etiological assessment. We aimed to determine whether invasive endovascular explorations may improve the diagnostic process and change the secondary prevention treat...

journal_title：BMC nephrology

authors： Ivanes F,Dewaele J,Touboul C,Gatault P,Sautenet B,Barbet C,Büchler M,Quilliet L,Angoulvant D,Halimi JM

更新日期：2020-07-14 00:00:00

abstract：BACKGROUND:Haemodialysis is the most common form of renal replacement therapy in Nigeria. The high cost of haemodialysis has made optimal therapy of end-stage renal disease difficult in Nigeria. This paper is a review of data collected over two years of provision of dialysis services in a new tertiary hospital in South...

journal_title：BMC nephrology

authors： Ekrikpo UE,Udo AI,Ikpeme EE,Effa EE

更新日期：2011-10-02 00:00:00

abstract：BACKGROUND:Atherosclerosis is regarded as a combination of two major separate diseases: atherosis and sclerosis. Sclerotic component depends on deterioration of elastic properties of the aortic wall and is called aortic stiffness. The most valuable, non-invasive method of aortic stiffness assessment is echocardiography...

journal_title：BMC nephrology

authors： Zapolski T,Furmaga J,Jaroszyński A,Wysocka A,Rudzki S,Wysokiński AP

更新日期：2017-01-23 00:00:00