Anti-neutrophil extracellular trap antibody in a patient with relapse of anti-neutrophil cytoplasmic antibody-associated vasculitis: a case report.

abstract：BACKGROUND:Liddle's syndrome is a rare monogenic form of hypertension caused by truncating or missense mutations in the C termini of the epithelial sodium channel (ENaC) β or γ subunits. Patients with this syndrome present with early onset of hypertension, hypokalemia, metabolic alkalosis, hyporeninemia and hypoaldoste...

journal_title：BMC nephrology

authors： Yamaguchi E,Yoshikawa K,Nakaya I,Kato K,Miyasato Y,Nakagawa T,Kakizoe Y,Mukoyama M,Soma J

更新日期：2018-05-23 00:00:00

abstract：BACKGROUND:Kidney injury molecule-1 (KIM-1) is a biomarker useful for detecting early tubular damage and has been recently reported as a useful marker for evaluating kidney injury in IgA nephropathy (IgAN). We therefore investigated whether treatment decreases urinary KIM-1 excretion in IgAN. METHODS:We prospectively ...

journal_title：BMC nephrology

authors： Seo MS,Park MY,Choi SJ,Jeon JS,Noh H,Kim JK,Han DC,Hwang SD,Jin SY,Kwon SH

更新日期：2013-07-09 00:00:00

abstract：BACKGROUND:The current literature recognises that left ventricular hypertrophy makes a key contribution to the high rate of premature cardiovascular mortality in dialysis patients. Determining how we might intervene to ameliorate left ventricular hypertrophy in dialysis populations has become a research priority. Reduc...

journal_title：BMC nephrology

authors： Dunlop JL,Vandal AC,de Zoysa JR,Gabriel RS,Haloob IA,Hood CJ,Matheson PJ,McGregor DO,Rabindranath KS,Semple DJ,Marshall MR

更新日期：2013-07-15 00:00:00

abstract：BACKGROUND:Studies suggest 24-h blood pressure (BP) variability has prognostic value for cardiovascular disease. Several factors associated with high 24-h BP variability are also common among individuals with chronic kidney disease (CKD). We hypothesized 24-h BP variability would be higher for individuals with versus w...

journal_title：BMC nephrology

authors： Tanner RM,Shimbo D,Dreisbach AW,Carson AP,Fox ER,Muntner P

更新日期：2015-06-18 00:00:00

abstract：BACKGROUND:Dose selection is an important step in pharmacokinetic (PK) studies of hemodialysis patients. We propose a simulation-based dose-selection method for PK studies of hemodialysis patients using a subpharmacological dose of oseltamivir as a model drug. METHODS:The concentrations of oseltamivir and its active m...

journal_title：BMC nephrology

authors： Kim DK,Lee JW,Shin KH,Kim S,Oh KH,Kim M,Yu KS,Lee JP,Lim CS,Kim YS,Joo KW

更新日期：2014-03-17 00:00:00

abstract：BACKGROUND:To date, limited research has been dedicated to exploring the experience of decision-making for chronic kidney disease (CKD) patients who have initiated dialysis and have to make decisions in the context of managing multiple illnesses. Evidence about the experience of decision-making for minority or disadvan...

journal_title：BMC nephrology

authors： Muscat DM,Kanagaratnam R,Shepherd HL,Sud K,McCaffery K,Webster A

更新日期：2018-11-27 00:00:00

abstract：BACKGROUND:Combined peritoneal dialysis (PD) and hemodialysis (HD) therapy (combined therapy) has numerous clinical benefits and should be emphasized for PD patients encountering technique failure. METHODS:This 12-year nationwide retrospective study was conducted to compare long-term outcomes (including admission and ...

journal_title：BMC nephrology

authors： Chung MC,Yu TM,Wu MJ,Chuang YW,Muo CH,Chen CH,Chang CH,Shieh JJ,Hung PH,Chen JW,Chung CJ

更新日期：2020-08-15 00:00:00

abstract：BACKGROUND:Echocardiographic characteristics across the spectrum of chronic kidney disease (CKD) have not been well described. We assessed the echocardiographic characteristics of patients with preserved renal function and mild or moderate CKD referred for echocardiography and determined whether echocardiographic param...

journal_title：BMC nephrology

authors： Mavrakanas TA,Khattak A,Singh K,Charytan DM

更新日期：2018-07-11 00:00:00

abstract：BACKGROUND:Chronic kidney disease (CKD) accelerates vascular stiffening related to age. Arterial stiffness may be evaluated measuring the carotid-femoral pulse wave velocity (PWV) or more simply, as recommended by KDOQI, monitoring pulse pressure (PP). Both correlate to survival and incidence of cardiovascular disease....

journal_title：BMC nephrology

authors： Salvadé I,Schätti-Stählin S,Violetti E,Schönholzer C,Cereghetti C,Zwahlen H,Berwert L,Burnier M,Gabutti L

更新日期：2015-04-23 00:00:00

abstract：BACKGROUND:African Americans have an increased incidence and worse prognosis with chronic kidney disease (CKD--estimated glomerular filtration rate [eGFR] <60 ml/min/1.73 m2) than their counterparts of European-descent. Inflammation has been related to renal disease in non-Hispanic whites, but there are limited data on...

journal_title：BMC nephrology

authors： Fox ER,Benjamin EJ,Sarpong DF,Nagarajarao H,Taylor JK,Steffes MW,Salahudeen AK,Flessner MF,Akylbekova EL,Fox CS,Garrison RJ,Taylor HA Jr

更新日期：2010-01-15 00:00:00

abstract：BACKGROUND:Chronic kidney disease (CKD) is an independent risk factor for cardiovascular disease (CVD) events, and a number of reports have shown a relationship between CKD and CVD in pre-dialysis or maintenance dialysis patients. However, few studies have reported serial observations during dialysis initiation and mai...

journal_title：BMC nephrology

authors： Inaguma D,Koide S,Takahashi K,Hayashi H,Hasegawa M,Yuzawa Y

更新日期：2017-02-28 00:00:00

abstract：BACKGROUND:The poorly differentiated renal cell carcinoma (RCC) with rhabdomyosarcomatous sarcomatoid differentiation shows a severely aggressive biological behavior characterized by rapid disease progression. Preoperative identification of the subtype with the prognostic factors and imaging features of sarcomatoid ren...

journal_title：BMC nephrology

authors： Liang X,Liu Y,Ran P,Tang M,Xu C,Zhu Y

更新日期：2018-04-10 00:00:00

abstract：BACKGROUND:Tolvaptan is a selective vasopressin receptor antagonist. Nitric Oxide (NO) promotes renal water and sodium excretion, but the effect is unknown in the nephron's principal cells. In a dose-response study, we measured the effect of tolvaptan on renal handling of water and sodium and systemic hemodynamics, dur...

journal_title：BMC nephrology

authors： Al Therwani S,Rosenbæk JB,Mose FH,Bech JN,Pedersen EB

更新日期：2017-03-13 00:00:00

abstract：BACKGROUND:Hypertension is a public health problem with mostly unknown causes, and where strong hereditary genetic alterations have not been fully elucidated. However, the use of experimental models has provided valuable information. Recent evidences suggest that alterations in key nephrogenic factors, such as Wilms' t...

journal_title：BMC nephrology

authors： Mazzei L,García M,Calvo JP,Casarotto M,Fornés M,Abud MA,Cuello-Carrión D,Ferder L,Manucha W

更新日期：2016-03-24 00:00:00

abstract：BACKGROUND:Cryofibrinogenemia is a rare disorder that mainly affects the skin and occasionally the kidney. However, there are few published reports of cryofibrinogenemia-associated renal pathology. We therefore report a patient with cryofibrinogen-associated glomerulonephritis. Samples from this patient were examined b...

journal_title：BMC nephrology

authors： Ibuki E,Shiraishi A,Sofue T,Kushida Y,Kadota K,Honda K,Kang D,Joh K,Minamino T,Haba R

更新日期：2020-01-29 00:00:00

abstract：BACKGROUND:Hepatocyte growth factor (HGF) counteracts peritoneal fibrosis in animal models and in-vitro studies, but no study explored effluent HGF in peritoneal dialysis (PD) patients with ultrafiltration failure (UFF). Our aim was to assess the relationship between effluent HGF with UF profile, free water transport (...

journal_title：BMC nephrology

authors： Bernardo AP,Oliveira JC,Santos O,Carvalho MJ,Cabrita A,Rodrigues A

更新日期：2014-12-17 00:00:00

abstract：BACKGROUND:Epithelioid angiomyolipoma is defined as potentially malignant mesenchymal neoplasm, characterized by proliferating epithelioid cells, whereas classic angiomyolipoma, composed of fat, smooth muscle cells and dysmorphic vessels, is defined as a potentially benign. The usual or classic angiomyolipoma is often ...

journal_title：BMC nephrology

authors： Tuma J,Moch H,Stuckmann G,Gysel W,Serra AL

更新日期：2018-05-30 00:00:00

abstract：BACKGROUND:Heavy metal poisoning can cause debilitating illness if left untreated, and its management in anuric patients poses challenges. Literature with which to guide clinical practice in this area is rather scattered. CASE PRESENTATION:We present a case of symptomatic lead and arsenic poisoning from use of Ayurved...

journal_title：BMC nephrology

authors： Hsiao CY,Gresham C,Marshall MR

更新日期：2019-10-17 00:00:00

abstract：BACKGROUND:Transfusion patterns are not well characterized in non-dialysis (ND) chronic kidney disease (CKD) patients. This study describes the proportion of patients transfused, units of blood transfused and trigger-hemoglobin (Hb) levels for transfusions in severe anemic, ND-CKD patients in routine practice. METHODS...

journal_title：BMC nephrology

authors： Fox KM,Yee J,Cong Z,Brooks JM,Petersen J,Lamerato L,Gandra SR

更新日期：2012-01-24 00:00:00

abstract：BACKGROUND:Abdominal aortic calcification assessed by X-ray is recommended to evaluate vascular calcification in dialysis patients. It has been shown that abdominal aortic calcification score (AACS) is a predictor of adverse outcomes in hemodialysis patients, but evidence regarding its prognostic value in peritoneal di...

journal_title：BMC nephrology

authors： Ma D,Yan H,Yang X,Yu Z,Ni Z,Fang W

更新日期：2020-04-30 00:00:00

abstract：BACKGROUND:The end stage renal disease population has a 20 fold higher incidence of cardiovascular mortality compared to the overall population. The development of reno-cardiac syndrome in these patients will result in cardiovascular events to be the cause of 50% of fatalities. There is therefore a need to research imp...

journal_title：BMC nephrology

authors： Kieswich JE,Chen J,Alliouachene S,Caton PW,McCafferty K,Thiemermann C,Yaqoob MM

更新日期：2018-12-04 00:00:00

abstract：BACKGROUND:The product of the concentrations of urinary tissue inhibitor of metalloproteinases-2 and insulin-like growth factor binding protein-7 (urinary [TIMP-2] × [IGFBP-7]) has been suggested as biomarker for early detection of acute kidney injury (AKI) in various clinical settings. However, the performance of urin...

journal_title：BMC nephrology

authors： Schiefer J,Lichtenegger P,Berlakovich GA,Plöchl W,Krenn CG,Baron DM,Baron-Stefaniak J,Faybik P

更新日期：2019-07-17 00:00:00

abstract：BACKGROUND:Gitelman syndrome (GS) is an autosomal recessive inherited salt-losing tubulopathy (SLT). Here, we describe, for the first time, a case of GS without Gitelman-like features and with concomitant kidney stones, cysts and diabetic nephropathy (DN). CASE PRESENTATION:We described a male patient had a 19-year hi...

journal_title：BMC nephrology

authors： Chen Q,Wang X,Min J,Wang L,Mou L

更新日期：2021-01-07 00:00:00

abstract：BACKGROUND:Autosomal dominant polycystic kidney disease (ADPKD) is the leading inheritable cause of end-stage renal disease (ESRD); however, the natural course of disease progression is heterogeneous between patients. This study aimed to develop a natural history model of ADPKD that predicted progression rates and long...

journal_title：BMC nephrology

authors： McEwan P,Bennett Wilton H,Ong ACM,Ørskov B,Sandford R,Scolari F,Cabrera MV,Walz G,O'Reilly K,Robinson P

更新日期：2018-02-13 00:00:00

abstract：BACKGROUND:Anaemia of chronic kidney disease increases the risk of death and adverse events, but can be managed using erythropoiesis stimulating agents (ESAs). However, recent evidence suggests that targeting a higher haemoglobin concentration ([Hb]) increases mortality risk, and both higher [Hb] targets and ESA doses ...

journal_title：BMC nephrology

authors： McMahon LP,Cai MX,Baweja S,Holt SG,Kent AB,Perkovic V,Leikis MJ,Becker GJ

更新日期：2012-06-15 00:00:00

abstract：BACKGROUND:MicroRNAs have been demonstrated to play an important role in the pathogenesis of diabetic nephropathy (DN). In this study, we investigated both the repertoire of miRNAs in the kidneys of patients with DN and their potential regulatory role in inflammation-mediated glomerular endothelial injury. METHODS:The...

journal_title：BMC nephrology

authors： Huang Y,Liu Y,Li L,Su B,Yang L,Fan W,Yin Q,Chen L,Cui T,Zhang J,Lu Y,Cheng J,Fu P,Liu F

更新日期：2014-09-02 00:00:00

abstract：BACKGROUND:Urinary Ca2+ excretion increases with dietary NaCl. NaCl-induced calciuria may be associated with hypertension, urinary stone formation and osteoporosis, but its mechanism and long-term effects are not fully understood. This study examined alterations in the expressions of renal Ca2+ transporters, channels a...

journal_title：BMC nephrology

authors： Yatabe MS,Yatabe J,Takano K,Murakami Y,Sakuta R,Abe S,Sanada H,Kimura J,Watanabe T

更新日期：2012-12-02 00:00:00

abstract：BACKGROUND:Neck of femur fractures are associated with high mortality and have increased prevalence in dialysis patients. Delays in operating on dialysis patients can occur as a result of logistical or medical issues; it has previously been shown that delays on operating on neck of femur fractures in the general popula...

journal_title：BMC nephrology

authors： Swift O,Ayub A,Mathavakkannan S,de Roeck N

更新日期：2016-03-03 00:00:00

abstract：BACKGROUND:Acute kidney injury (AKI) remains a frequent complication in children undergoing hematopoietic stem cell transplantation (HSCT) and an independent risk factor of the patient's survival and a prognostic factor of progression to chronic kidney disease (CKD). However, the causes of these complications are diver...

journal_title：BMC nephrology

authors： Hirano D,Kakegawa D,Miwa S,Umeda C,Takemasa Y,Tokunaga A,Kawakami Y,Ito A

更新日期：2020-08-27 00:00:00

abstract：BACKGROUND:Lupus nephritis (LN) is a severe consequence of systemic lupus erythematosus (SLE) that affects approximately 40% of patients. Pathogenic immune complexes that are characteristic of LN deposit in the kidney and activate immune mediated pathways including the complement system. Complete remission rates in LN ...

journal_title：BMC nephrology

authors： Wright RD,Bannerman F,Beresford MW,Oni L

更新日期：2020-06-30 00:00:00