Urinary [TIMP-2] × [IGFBP-7] for predicting acute kidney injury in patients undergoing orthotopic liver transplantation.

abstract：BACKGROUND:MicroRNAs have been demonstrated to play an important role in the pathogenesis of diabetic nephropathy (DN). In this study, we investigated both the repertoire of miRNAs in the kidneys of patients with DN and their potential regulatory role in inflammation-mediated glomerular endothelial injury. METHODS:The...

journal_title：BMC nephrology

authors： Huang Y,Liu Y,Li L,Su B,Yang L,Fan W,Yin Q,Chen L,Cui T,Zhang J,Lu Y,Cheng J,Fu P,Liu F

更新日期：2014-09-02 00:00:00

abstract：BACKGROUND:Patients with end-stage renal disease (ESRD) under hemodialysis (HD) are at greater risks of infectious spondylitis (IS), but there is no reliable predictor that facilitate early detection of this relatively rare and insidious disease. METHODS:A retrospective review of the medical records from patients with...

journal_title：BMC nephrology

authors： Lu KL,Huang WH,Lu YA,Lin CY,Wu HH,Hsu CW,Weng CH,Wu CY,Wu IW,Wu MY,Yen TH,Yang HY

更新日期：2019-08-16 00:00:00

abstract：BACKGROUND:The poorly differentiated renal cell carcinoma (RCC) with rhabdomyosarcomatous sarcomatoid differentiation shows a severely aggressive biological behavior characterized by rapid disease progression. Preoperative identification of the subtype with the prognostic factors and imaging features of sarcomatoid ren...

journal_title：BMC nephrology

authors： Liang X,Liu Y,Ran P,Tang M,Xu C,Zhu Y

更新日期：2018-04-10 00:00:00

abstract：BACKGROUND:Family members of patients with end stage renal disease were reported to have an increased prevalence of chronic kidney disease (CKD). However, studies differentiated genetic and non-genetic family members are limited. We sought to investigate the prevalence of CKD among fist-degree relatives and spouses of ...

journal_title：BMC nephrology

authors： Kong X,Liu L,Zuo L,Yuan P,Li Z,Li W,Cai M,Chen X,Jiang A,Long G,Xu J,Lin H,Wang S,Huang W,Wang Y,Guo Y,Cao P,Wu H,Jia Q,Zhang L,Wang M,Wang H

更新日期：2013-01-18 00:00:00

abstract：BACKGROUND:Critically ill coronavirus disease 2019 (COVID-19) patients have a high risk of acute kidney injury (AKI) that requires renal replacement therapy (RRT). A state of hypercoagulability reduces circuit life spans. To maintain circuit patency and therapeutic efficiency, an optimized anticoagulation strategy is n...

journal_title：BMC nephrology

authors： Arnold F,Westermann L,Rieg S,Neumann-Haefelin E,Biever PM,Walz G,Kalbhenn J,Tanriver Y

更新日期：2020-11-16 00:00:00

abstract：BACKGROUND:Alport syndrome and ANCA-associated vasculitis are both rare diseases. The co-existence of these two conditions has never been reported. There is no obvious pathogenic link between these two glomerular diseases. The management of this case highlights the importance of a systematic approach when investigating...

journal_title：BMC nephrology

authors： Gillion V,Jadoul M,Aydin S,Godefroid N

更新日期：2017-03-29 00:00:00

abstract：BACKGROUND:The pathogenesis of falling is complex, and identification of risk factors may be essential for prevention. The relationship between renal disease and falls is unclear, and the goal of this study was to collect the available evidence and investigate the relationship between accidental falls and renal dysfunc...

journal_title：BMC nephrology

authors： López-Soto PJ,De Giorgi A,Senno E,Tiseo R,Ferraresi A,Canella C,Rodríguez-Borrego MA,Manfredini R,Fabbian F

更新日期：2015-10-29 00:00:00

abstract：BACKGROUND:Chronic kidney disease (CKD) is characterized by dysbiosis, elevated levels of uremic toxins, systemic inflammation, and increased markers of oxidative stress. These factors lead to an increased risk of cardiovascular disease (CVD) which is common among CKD patients. Supplementation with high amylose maize r...

journal_title：BMC nephrology

authors： Headley SA,Chapman DJ,Germain MJ,Evans EE,Hutchinson J,Madsen KL,Ikizler TA,Miele EM,Kirton K,O'Neill E,Cornelius A,Martin B,Nindl B,Vaziri ND

更新日期：2020-11-26 00:00:00

abstract：BACKGROUND:In patients with autosomal dominant polycystic kidney disease (ADPKD), malnutrition may develop as renal function declines and the abdominal organs become enlarged. We investigated the relationship of intra-abdominal mass with nutritional status. METHODS:This cross-sectional study was performed at a tertiar...

journal_title：BMC nephrology

authors： Ryu H,Kim H,Park HC,Kim H,Cho EJ,Lee KB,Chung W,Oh KH,Cho JY,Hwang YH,Ahn C

更新日期：2017-01-14 00:00:00

abstract：BACKGROUND:Variants in CUBN, the gene encoding cubilin, a proximal tubular transport protein, have been associated with albuminuria and vitamin B12 (B12) deficiency. We hypothesized that low levels of B12 would be associated with albuminuria in a population-based cohort. METHODS:We analyzed participants from the Frami...

journal_title：BMC nephrology

authors： McMahon GM,Hwang SJ,Tanner RM,Jacques PF,Selhub J,Muntner P,Fox CS

更新日期：2015-02-02 00:00:00

abstract：BACKGROUND:Neutrophil gelatinase associated lipocalin (NGAL) is a highly predictive biomarker of acute kidney injury. To understand the role of NGAL in renal injury during sepsis, we investigated the temporal changes and biological sources of NGAL in a rat model of acute kidney injury, and explored the relationship bet...

journal_title：BMC nephrology

authors： Han M,Li Y,Liu M,Li Y,Cong B

更新日期：2012-06-27 00:00:00

abstract：BACKGROUND:Patients with chronic kidney disease (CKD) have a high risk of recurring thrombotic events following acute myocardial infarction (AMI). Microparticles (MPs) are circulating small vesicles shed from various cells. Platelet microparticles (PMPs) reflect platelet activation and endothelial microparticles (EMPs)...

journal_title：BMC nephrology

authors： Mörtberg J,Lundwall K,Mobarrez F,Wallén H,Jacobson SH,Spaak J

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:Some nephrologists have advocated an individualized approach to the prescription of bicarbonate hemodialysis. However, the utility of monthly serum bicarbonate levels for guiding and evaluating such treatment decisions has not been evaluated. We sought to define the variability of these measurements and to d...

journal_title：BMC nephrology

authors： Patel R,Paredes W,Hall CB,Nader MA,Sapkota D,Folkert VW,Abramowitz MK

更新日期：2015-12-21 00:00:00

abstract：BACKGROUND:Acute kidney injury (AKI) places a heavy burden on the healthcare system in China and is usually misdiagnosed. However, there are limited studies that have described the epidemiology and diagnosis of AKI in China. The aim of this study was to describe the incidence and diagnosis of AKI in hospitalized adult ...

journal_title：BMC nephrology

authors： Cheng X,Wu B,Liu Y,Mao H,Xing C

更新日期：2017-06-24 00:00:00

abstract：BACKGROUND:Dialysis has long been a critical issue in the field of nephrology, though the burden this lifesaving technology places on society can be immense. Effectively increasing the health literacy of hemodialysis patients can be beneficial for their health outcomes and self-care abilities. Thus, the aims of this st...

journal_title：BMC nephrology

authors： Shih CL,Chang TH,Jensen DA,Chiu CH

更新日期：2016-05-31 00:00:00

abstract：BACKGROUND:Nephrotic syndrome (NS) is pathological condition characterized by heavy proteinuria. Our study investigates hypothesis that change in cell proliferation of proximal tubules influences primary cilia structure and function and promotes cystogenesis in congenital nephrotic syndrome of the Finnish type (CNF) an...

journal_title：BMC nephrology

authors： Saraga M,Vukojević K,Krželj V,Puretić Z,Bočina I,Durdov MG,Weber S,Dworniczak B,Ljubanović DG,Saraga-Babić M

更新日期：2014-01-08 00:00:00

abstract：BACKGROUND:The current practice concerning timing, mode, and dose of renal replacement therapy (RRT) in patients with metformin-associated lactic acidosis (MALA) with renal failure remains unknown. To investigate whether serum lactate level and prescription pattern of RRT are associated with mortality in patients with ...

journal_title：BMC nephrology

authors： Yeh HC,Ting IW,Tsai CW,Wu JY,Kuo CC

更新日期：2017-07-10 00:00:00

abstract：BACKGROUND:About 1% of patients admitted to the Emergency Department (ED) have hypernatremia, a condition associated with a mortality rate of 20 to 60%. Management recommendations originate from intensive care unit studies, in which patients and medical diseases differ from those in ED. METHODS:We retrospectively stud...

journal_title：BMC nephrology

authors： Bataille S,Baralla C,Torro D,Buffat C,Berland Y,Alazia M,Loundou A,Michelet P,Vacher-Coponat H

更新日期：2014-02-21 00:00:00

abstract：BACKGROUND:The risk of an individual to develop an acute kidney injury (AKI), or its severity, cannot be reliably predicted by common clinical risk factors. Whether genetic risk factors have an explanatory role poses an interesting question, however. Thus, we conducted a systematic literature review regarding genetic p...

journal_title：BMC nephrology

authors： Vilander LM,Kaunisto MA,Pettilä V

更新日期：2015-12-02 00:00:00

abstract：BACKGROUND:The burden of kidney diseases is reported to be higher in lower- and middle-income countries as compared to developed countries, and countries in sub-Saharan Africa are reported to be most affected. Health systems in most sub-Sahara African countries have limited capacity in the form of trained and skilled h...

journal_title：BMC nephrology

authors： Furia FF,Shoo J,Ruggajo PJ,Kilonzo K,Basu G,Yeates K,Varughese S,Svarstad E,Kisanga O

更新日期：2019-10-17 00:00:00

abstract：BACKGROUND:Rituximab is widely used in kidney transplantation. However, it is not clear whether the conventional doses of maintenance immunosuppressant in rituximab-treated kidney transplantation (KT) are appropriate. In our previous study, decreasing mycophenolate mofetil (MMF) dose due to infection did not increase t...

journal_title：BMC nephrology

authors： Baek CH,Kim H,Yu H,Shin E,Cho H,Yang WS,Han DJ,Park SK

更新日期：2015-12-04 00:00:00

abstract：BACKGROUND:The high cost, complexity of the available protocols, and metabolic complications are the major barriers that impede the clinical utilization of regional citrate anticoagulation (RCA) for sustained low efficiency dialysis (SLED) in critically ill patients. By comparing a novel protocol for SLED using 30% cit...

journal_title：BMC nephrology

authors： Wen M,Küchle C,Steubl D,Satanovskji R,Heemann U,Suttmann Y,Angermann S,Kemmner S,Rehbehn L,Huber M,Hauser C,Schmaderer C,Reichelt AL,Haller B,Renders L

更新日期：2018-04-03 00:00:00

abstract：BACKGROUND:The current literature recognises that left ventricular hypertrophy makes a key contribution to the high rate of premature cardiovascular mortality in dialysis patients. Determining how we might intervene to ameliorate left ventricular hypertrophy in dialysis populations has become a research priority. Reduc...

journal_title：BMC nephrology

authors： Dunlop JL,Vandal AC,de Zoysa JR,Gabriel RS,Haloob IA,Hood CJ,Matheson PJ,McGregor DO,Rabindranath KS,Semple DJ,Marshall MR

更新日期：2013-07-15 00:00:00

abstract：BACKGROUND:Renal injury is a serious complication after cardiac surgery and therefore, early detection and much more prediction of postoperative kidney injury is desirable. Neutrophil gelatinase-associated lipocalin (NGAL) is a predictive biomarker of acute kidney injury and may increase after cardiopulmonary bypass (C...

journal_title：BMC nephrology

authors： Friedrich MG,Bougioukas I,Kolle J,Bireta C,Jebran FA,Placzek M,Tirilomis T

更新日期：2017-02-21 00:00:00

abstract：BACKGROUND:Previous studies have linked smaller kidney dimensions to increased blood pressure. However, patients with Balkan Endemic Nephropathy (BEN), whose kidneys shrink during the course of the disease, do not manifest increased blood pressure. The authors evaluated the relationship between kidney cortex width, kid...

journal_title：BMC nephrology

authors： Dimitrov PS,Simeonov VA,Tsolova SD,Bonev AG,Georgieva RB,Karmaus WJ

更新日期：2006-08-23 00:00:00

abstract：BACKGROUND:ANCA-associated vasculitis is a life-threatening, systemic autoimmune disease. There is an increased risk of organ infarction but in many cases this is asymptomatic. We described here the first reported case of PR3 vasculitis presenting with symptomatic bilateral renal wedge infarction. CASE PRESENTATION:A ...

journal_title：BMC nephrology

authors： Bottomley MJ,Gibson M,Alchi B

更新日期：2019-03-06 00:00:00

abstract：BACKGROUND:Anaemia of chronic kidney disease increases the risk of death and adverse events, but can be managed using erythropoiesis stimulating agents (ESAs). However, recent evidence suggests that targeting a higher haemoglobin concentration ([Hb]) increases mortality risk, and both higher [Hb] targets and ESA doses ...

journal_title：BMC nephrology

authors： McMahon LP,Cai MX,Baweja S,Holt SG,Kent AB,Perkovic V,Leikis MJ,Becker GJ

更新日期：2012-06-15 00:00:00

abstract：BACKGROUND:Aluminium (Al) toxicity was frequent in the 1980s in patients ingesting Al containing phosphate binders (Alucaps) whilst having HD using water potentially contaminated with Al. The aim of this study was to determine the risk of Al toxicity in HD patients receiving Alucaps but never exposed to contaminated di...

journal_title：BMC nephrology

authors： Pepper R,Campbell N,Yaqoob MM,Roberts NB,Fan SL

更新日期：2011-10-12 00:00:00

abstract：INTRODUCTION:Urinary biomarkers of kidney injury are presumed to reflect renal tubular damage. However, their concentrations may be influenced by other factors, such as hematuria or pyuria. We sought to examine what non-injury related urinalysis factors are associated with urinary biomarker levels. METHODS:We examined...

journal_title：BMC nephrology

authors： Nadkarni GN,Coca SG,Meisner A,Patel S,Kerr KF,Patel UD,Koyner JL,Garg AX,Philbrook HT,Edelstein CL,Shlipak M,El-Khoury J,Parikh CR,TRIBE-AKI Consortium Investigators.

更新日期：2017-07-06 00:00:00

abstract：BACKGROUND:Proteinuria after kidney transplantation portends a worse graft survival. However the magnitude of proteinuria related to patient and graft survival and its correlation with donor and recipient characteristics are poorly explored. METHODS:This study investigated the impact of post transplant proteinuria in ...

journal_title：BMC nephrology

authors： Diena D,Messina M,De Biase C,Fop F,Scardino E,Rossetti MM,Barreca A,Verri A,Biancone L

更新日期：2019-12-02 00:00:00