Do oral aluminium phosphate binders cause accumulation of aluminium to toxic levels?

abstract：BACKGROUND:Metabolic acidosis leads to chronic kidney disease (CKD) progression. The guidelines recommend a lower limit of serum bicarbonate level, but no upper limit. For serum bicarbonate level to be clinically useful as a therapeutic target marker, it is necessary to investigate the target serum bicarbonate level wi...

journal_title：BMC nephrology

authors： Kanda E,Ai M,Yoshida M,Kuriyama R,Shiigai T

更新日期：2013-01-09 00:00:00

abstract：BACKGROUND:Chronic kidney disease (CKD) is increasingly being recognized as a predictor for both end-stage renal disease and cardiovascular disease. The present study, conducted on individuals from a community in Arita, Japan, was designed to evaluate biomarkers that can be used to determine the associated factors for ...

journal_title：BMC nephrology

authors： Takamatsu N,Abe H,Tominaga T,Nakahara K,Ito Y,Okumoto Y,Kim J,Kitakaze M,Doi T

更新日期：2009-10-27 00:00:00

abstract：BACKGROUND:Immunoglobulin light chains are classified as middle molecule uremic toxins able to interact with B lymphocyte membranes leading to the activation of transmembrane signaling. The ensuing impairment of neutrophil function can contribute to the chronic inflammation state of uremic patients, and the increased r...

journal_title：BMC nephrology

authors： Donati G,Moretti MI,Baraldi O,Spazzoli A,Capelli I,Comai G,Marchetti A,Sarma M,Mancini R,La Manna G

更新日期：2016-11-25 00:00:00

abstract：BACKGROUND:Peripheral arterial disease (PAD) is common in patients with end-stage renal disease on hemodialysis, but is frequently underdiagnosed. The risk factors for PAD are well known within the general population, but they differ somewhat in hemodialysis patients. This study aimed to determine the prevalence of PAD...

journal_title：BMC nephrology

authors： Ašćerić RR,Dimković NB,Trajković GŽ,Ristić BS,Janković AN,Durić PS,Ilijevski NS

更新日期：2019-07-26 00:00:00

abstract：BACKGROUND:Heavy metal poisoning can cause debilitating illness if left untreated, and its management in anuric patients poses challenges. Literature with which to guide clinical practice in this area is rather scattered. CASE PRESENTATION:We present a case of symptomatic lead and arsenic poisoning from use of Ayurved...

journal_title：BMC nephrology

authors： Hsiao CY,Gresham C,Marshall MR

更新日期：2019-10-17 00:00:00

abstract：BACKGROUND:The possibility of clearing Cell-free Plasma Hemoglobin (CPH) from human plasma may appear attractive, especially when considering the noxious effects that CPH has on the immune function and the renal damage caused by its filtration. The existence of the so-called High Cut-Off (HCO) filters, possessing pores...

journal_title：BMC nephrology

authors： Cucchiari D,Reverter E,Blasco M,Molina-Andujar A,Carpio A,Sanz M,Escorsell A,Fernández J,Poch E

更新日期：2018-10-04 00:00:00

abstract：BACKGROUND:A marked reduction in serum levels of bioactive insulin-like growth factor-I (IGF-I) has been observed in fasting hemodialysis (HD) patients during a 4-h HD session. The aim of the present study was to investigate the beneficial effect of hyperinsulinemia during HD on bioactive IGF-I and inflammatory biomark...

journal_title：BMC nephrology

authors： Reinhard M,Frystyk J,Jespersen B,Bjerre M,Christiansen JS,Flyvbjerg A,Ivarsen P

更新日期：2013-04-04 00:00:00

abstract：BACKGROUND:Despite the urgent need for evidence to guide the end-of-life (EOL) care for patients with chronic kidney disease (CKD), we have limited knowledge of the costs and intensity of EOL care in this population. The present study examined patterns and predictors for EOL care intensity among elderly patients with C...

journal_title：BMC nephrology

authors： Chen B,Fan VY,Chou YJ,Kuo CC

更新日期：2017-01-26 00:00:00

abstract：BACKGROUND:Recently there has been a progressive loss of specialty related skills for nephrologists. Among the skills we find the kidney biopsy that has a central role in diagnosis of renal parenchymal disease. One of the causes might be the belief that the kidney biopsy should be performed only in larger Centers which...

journal_title：BMC nephrology

authors： Esposito V,Mazzon G,Baiardi P,Torreggiani M,Semeraro L,Catucci D,Colucci M,Mariotto A,Grosjean F,Bovio G,Esposito C

更新日期：2018-01-15 00:00:00

abstract：BACKGROUND:Diabetic nephropathy (DN) is a primary complication of diabetes mellitus (DM). The pathology of DN is still vague, and diagnostic accuracy is not enough. This study was performed to identify miRNAs and genes that have possibilities of being used as therapeutic targets for DN in type 2 DM. METHODS:Human miRN...

journal_title：BMC nephrology

authors： Yu Y,Jia YY,Wang M,Mu L,Li HJ

更新日期：2021-01-12 00:00:00

abstract：BACKGROUND:Anabolic-androgenic steroids and growth hormone are among the most commonly used supplements by sportsmen and sportswomen. The aim of this systematic review is to collect and report available data about renal safety of anabolic-androgenic steroids and growth hormone (GH). METHODS:The search strategy was in ...

journal_title：BMC nephrology

authors： Davani-Davari D,Karimzadeh I,Khalili H

更新日期：2019-05-31 00:00:00

abstract：BACKGROUND:The extent to which smoking contributes to adverse outcomes among men and women of all ages undergoing dialysis is uncertain. The objective of this study was to determine the differential impact of smoking on risks of mortality and kidney transplantation by age and by sex at dialysis initiation. METHODS:We ...

journal_title：BMC nephrology

authors： Stack AG,Yermak D,Roche DG,Ferguson JP,Elsayed M,Mohammed W,Casserly LF,Walsh SR,Cronin CJ

更新日期：2016-07-26 00:00:00

abstract：BACKGROUND:To measure health-related and care-related quality of life among informal caregivers of older people with end-stage kidney disease (ESKD), and to determine the association between caregiver quality of life and care recipient's treatment type. METHODS:A prospective cross-sectional study was conducted. Three ...

journal_title：BMC nephrology

authors： Shah KK,Murtagh FEM,McGeechan K,Crail SM,Burns A,Morton RL

更新日期：2020-05-04 00:00:00

abstract：BACKGROUND:Cardiovascular morbidity and mortality are highly prevalent in patients with end-stage renal disease, and osteoprotegerin (OPG) may be an important link between bone loss and vascular calcification. This study was conducted to evaluate the relationship between central arterial stiffness and serum OPG levels ...

journal_title：BMC nephrology

authors： Hou JS,Lin YL,Wang CH,Lai YH,Kuo CH,Subeq YM,Hsu BG

更新日期：2019-05-23 00:00:00

abstract：:Attention has recently been focused on addressing the problem of acute kidney injury in both the developed and developing world. Little information is actually available on the incidence and management of AKI in low resource settings. Thus, the paper by Bagasha in the current issue of BMC Nephrology makes an important...

journal_title：BMC nephrology

authors： Anand S,Cruz DN,Finkelstein FO

更新日期：2015-01-16 00:00:00

abstract：BACKGROUND:Different measures of non-adherence to immunosuppressant (IS) medication have been found to be associated with rejection episodes after successful transplantation. The aim of the current study was to investigate whether graft rejection after renal transplantation is associated with patient-reported IS medica...

journal_title：BMC nephrology

authors： Scheel J,Reber S,Stoessel L,Waldmann E,Jank S,Eckardt KU,Grundmann F,Vitinius F,de Zwaan M,Bertram A,Erim Y

更新日期：2017-03-29 00:00:00

abstract：BACKGROUND:Patients with an impaired renal function show a high incidence of bone and mineral disturbances. These 'chronic kidney disease - mineral and bone disorders' (CKD-MBD) range from high turnover osteoporosis to adynamic bone disease. Currently, the histomorphometric analysis of a bone biopsy taken from the ilia...

journal_title：BMC nephrology

authors： Hiller RG,Patecki M,Neunaber C,Reifenrath J,Kielstein JT,Kielstein H

更新日期：2017-04-13 00:00:00

abstract：BACKGROUND:Tolvaptan is a selective vasopressin receptor antagonist. Nitric Oxide (NO) promotes renal water and sodium excretion, but the effect is unknown in the nephron's principal cells. In a dose-response study, we measured the effect of tolvaptan on renal handling of water and sodium and systemic hemodynamics, dur...

journal_title：BMC nephrology

authors： Al Therwani S,Rosenbæk JB,Mose FH,Bech JN,Pedersen EB

更新日期：2017-03-13 00:00:00

abstract：BACKGROUND:Chronic kidney disease (CKD) and coronary artery disease (CAD) are independently associated with increased vascular stiffness. We examined whether renal function contributes to vascular stiffness independently of CAD status. METHODS:We studied 160 patients with CAD and 169 subjects without CAD. The 4-variab...

journal_title：BMC nephrology

authors： Rossi SH,McQuarrie EP,Miller WH,Mackenzie RM,Dymott JA,Moreno MU,Taurino C,Miller AM,Neisius U,Berg GA,Valuckiene Z,Hannay JA,Dominiczak AF,Delles C

更新日期：2013-08-13 00:00:00

abstract：BACKGROUND:Alport syndrome and ANCA-associated vasculitis are both rare diseases. The co-existence of these two conditions has never been reported. There is no obvious pathogenic link between these two glomerular diseases. The management of this case highlights the importance of a systematic approach when investigating...

journal_title：BMC nephrology

authors： Gillion V,Jadoul M,Aydin S,Godefroid N

更新日期：2017-03-29 00:00:00

abstract：BACKGROUND:African Americans have an increased incidence and worse prognosis with chronic kidney disease (CKD--estimated glomerular filtration rate [eGFR] <60 ml/min/1.73 m2) than their counterparts of European-descent. Inflammation has been related to renal disease in non-Hispanic whites, but there are limited data on...

journal_title：BMC nephrology

authors： Fox ER,Benjamin EJ,Sarpong DF,Nagarajarao H,Taylor JK,Steffes MW,Salahudeen AK,Flessner MF,Akylbekova EL,Fox CS,Garrison RJ,Taylor HA Jr

更新日期：2010-01-15 00:00:00

abstract：BACKGROUND:This is the first study that has examined non-cardiac incidental findings in research cardiac computed tomography (CT) of hemodialysis patients and their relationship with patient characteristics. METHODS:We performed a cross-sectional analysis in the Predictors of Arrhythmic and Cardiovascular Events in En...

journal_title：BMC nephrology

authors： Jaar BG,Zhang L,Chembrovich SV,Sozio SM,Shafi T,Scialla JJ,Tomaselli GF,Lima JA,Kao WH,Parekh RS,Meoni LA

更新日期：2014-05-01 00:00:00

abstract：BACKGROUND:Poor physical performance and protein-energy wasting (PEW) are health issues of major concern in haemodialysis patients. The conventional haemodialysis (CHD) regime, three times per week 3-5 h, is subject of discussion because of high morbidity and mortality rates. When patients switch from CHD to longer dia...

journal_title：BMC nephrology

authors： Dam M,Neelemaat F,Struijk-Wielinga T,Weijs PJ,van Jaarsveld BC

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Protein-bound uremic toxins are associated with poor outcomes in patients with chronic kidney disease. The aim of this study is to investigate the relationship between indoxyl sulfate (IS), a protein-bound solute, and 90-day mortality in patients with acute kidney injury. METHODS:Adults with hospital-acquir...

journal_title：BMC nephrology

authors： Wang W,Hao G,Pan Y,Ma S,Yang T,Shi P,Zhu Q,Xie Y,Ma S,Zhang Q,Ruan H,Ding F

更新日期：2019-02-14 00:00:00

abstract：BACKGROUND:Until now, no long-term studies relating serum albumin level to mortality rate in prevalent haemodialysis (HD) patients have been conducted. We aimed to examine the association between serum albumin level and mortality over a 5-year period. METHODS:This study included 781 patients who received maintenance H...

journal_title：BMC nephrology

authors： Chen JB,Cheng BC,Yang CH,Hua MS

更新日期：2016-08-20 00:00:00

abstract：BACKGROUND:End-Stage Renal disease (ESRD) is associated with increased morbidity and mortality. We assessed the occurrence, time-trend and determinants of fatal outcomes of haemodialysis-treated ESRD patients over a 10-year period in a major referral hospital in Cameroon. METHODS:Medical records of ESRD patients who s...

journal_title：BMC nephrology

authors： Halle MP,Ashuntantang G,Kaze FF,Takongue C,Kengne AP

更新日期：2016-11-03 00:00:00

abstract：BACKGROUND:Group A streptococcus (GAS) is an etiological agent for the immune mediated sequela post streptococcal glomerulonephritis (PSGN). In some populations PSGN is recognized as a risk factor for chronic kidney disease (CKD) and end-stage renal disease (ESRD). It was found that a significantly greater proportion o...

journal_title：BMC nephrology

authors： Karmarkar MG,Hule GP,Hase NK,Mehta PR,Walter SR,Sriprakash KS

更新日期：2013-05-06 00:00:00

abstract：BACKGROUND:Bleeding severity, anatomic location, tissue characteristics, and visibility are common challenges encountered while managing intraoperative bleeding, and conventional hemostatic measures (suture, ligature, and cautery) may sometimes be ineffective or impractical. While topical absorbable hemostats (TAH) are...

journal_title：BMC nephrology

authors： Nativ O,Patel B,Shen J,Batiller J,Horn S,Hart JC

更新日期：2012-11-08 00:00:00

abstract：BACKGROUND:Some nephrologists have advocated an individualized approach to the prescription of bicarbonate hemodialysis. However, the utility of monthly serum bicarbonate levels for guiding and evaluating such treatment decisions has not been evaluated. We sought to define the variability of these measurements and to d...

journal_title：BMC nephrology

authors： Patel R,Paredes W,Hall CB,Nader MA,Sapkota D,Folkert VW,Abramowitz MK

更新日期：2015-12-21 00:00:00

abstract：BACKGROUND:Ghrelin, a gastric orexigenic peptide, and body mass index (BMI) are known as inversely associated to each other and are both linked to cardiovascular (CV) risk and mortality in maintenance hemodialysis (MHD) patients. However, it is unclear whether the interaction between ghrelin and BMI is associated with ...

journal_title：BMC nephrology

authors： Beberashvili I,Sinuani I,Azar A,Shapiro G,Feldman L,Doenyas-Barak K,Stav K,Efrati S

更新日期：2017-01-18 00:00:00