Impaired renal function impacts negatively on vascular stiffness in patients with coronary artery disease.

abstract：BACKGROUND:Use of serum creatinine to estimate GFR may lead to underestimation of the association between self-reported frailty and kidney function. Our objectives were to evaluate the association of measured GFR (mGFR) with self-reported frailty among patients with CKD and to determine whether self-reported frailty wa...

journal_title：BMC nephrology

authors： Delgado C,Grimes BA,Glidden DV,Shlipak M,Sarnak MJ,Johansen KL

更新日期：2015-12-09 00:00:00

abstract：BACKGROUND:Lower serum bicarbonate, mainly due to the modern Western-style diet, and renal hyperfiltration (RHF) are both independently associated with higher mortality in the general population with preserved renal function. The objective of this study was to evaluate the association between serum bicarbonate and RHF....

journal_title：BMC nephrology

authors： Park M,So R,Joo KW,Yoon HJ

更新日期：2016-01-06 00:00:00

abstract：BACKGROUND:Renal injury is a serious complication after cardiac surgery and therefore, early detection and much more prediction of postoperative kidney injury is desirable. Neutrophil gelatinase-associated lipocalin (NGAL) is a predictive biomarker of acute kidney injury and may increase after cardiopulmonary bypass (C...

journal_title：BMC nephrology

authors： Friedrich MG,Bougioukas I,Kolle J,Bireta C,Jebran FA,Placzek M,Tirilomis T

更新日期：2017-02-21 00:00:00

abstract：BACKGROUND:Despite improvement in short-term outcome of kidney transplants, the long-term survival of kidney transplants has not changed over past decades. Kidney biopsy is the gold standard of transplant pathology but it's invasive. Quantification of transplant blood flow could provide a novel non-invasive method to e...

journal_title：BMC nephrology

authors： Päivärinta J,Oikonen V,Räisänen-Sokolowski A,Tolvanen T,Löyttyniemi E,Iida H,Nuutila P,Metsärinne K,Koivuviita N

更新日期：2019-11-27 00:00:00

abstract：BACKGROUND:Complement activation plays a substantial role in the pathogenesis of primary membranous nephropathy (pMN). C5b-9, C3c, MBL, and factor B have been documented in the subepithelial immune deposits. However, the changing of complement activation products in circulation and urine is not clear. METHODS:We measu...

journal_title：BMC nephrology

authors： Zhang MF,Huang J,Zhang YM,Qu Z,Wang X,Wang F,Meng LQ,Cheng XY,Cui Z,Liu G,Zhao MH

更新日期：2019-08-09 00:00:00

abstract：BACKGROUND:Thermometers that measure core (internal) body temperature are the gold standard for monitoring temperature. Despite that most modern hemodialysis machines are equipped with an internal blood monitor that measures core body temperature, current practice is to use peripheral thermometers. A better understandi...

journal_title：BMC nephrology

authors： Lunney M,Tonelli B,Lewis R,Wiebe N,Thomas C,MacRae J,Tonelli M

更新日期：2018-06-14 00:00:00

abstract：BACKGROUND:Hemodiafiltration (HDF), as a convective blood purification technique, has been associated with favorable outcomes improved phosphate control, removal of middle-molecules such as Beta2-microglobulin and the occurrence of intradialytic hypotension (IDH) as compared to diffusive techniques. The aim of this ret...

journal_title：BMC nephrology

authors： Mora-Bravo FG,De-La-Cruz G,Rivera S,Ramírez AM,Raimann JG,Pérez-Grovas H

更新日期：2012-09-10 00:00:00

abstract：BACKGROUND:There is a lack of online, evidence-based information and resources to support home-based care of childhood CKD stages 3-5. METHODS:Qualitative interviews were undertaken with parents, patients and professionals to explore their views on content of the proposed online parent information and support (OPIS) w...

journal_title：BMC nephrology

authors： Swallow VM,Hall AG,Carolan I,Santacroce S,Webb NJ,Smith T,Hanif N

更新日期：2014-02-18 00:00:00

abstract：BACKGROUND:Epithelioid angiomyolipoma is defined as potentially malignant mesenchymal neoplasm, characterized by proliferating epithelioid cells, whereas classic angiomyolipoma, composed of fat, smooth muscle cells and dysmorphic vessels, is defined as a potentially benign. The usual or classic angiomyolipoma is often ...

journal_title：BMC nephrology

authors： Tuma J,Moch H,Stuckmann G,Gysel W,Serra AL

更新日期：2018-05-30 00:00:00

abstract：BACKGROUND:Chloride is speculated to have nephrotoxic properties. In healthy subjects we tested the hypothesis that acute chloride loading with 3% saline would induce kidney injury, which could be prevented with the loop-diuretic furosemide. METHODS:The study was designed as a randomized, placebo-controlled, crossover...

journal_title：BMC nephrology

authors： Mose FH,Jörgensen AN,Vrist MH,Ekelöf NP,Pedersen EB,Bech JN

更新日期：2019-06-03 00:00:00

abstract：BACKGROUND:The pathogenesis of falling is complex, and identification of risk factors may be essential for prevention. The relationship between renal disease and falls is unclear, and the goal of this study was to collect the available evidence and investigate the relationship between accidental falls and renal dysfunc...

journal_title：BMC nephrology

authors： López-Soto PJ,De Giorgi A,Senno E,Tiseo R,Ferraresi A,Canella C,Rodríguez-Borrego MA,Manfredini R,Fabbian F

更新日期：2015-10-29 00:00:00

abstract：BACKGROUND:Hepatocyte growth factor (HGF) counteracts peritoneal fibrosis in animal models and in-vitro studies, but no study explored effluent HGF in peritoneal dialysis (PD) patients with ultrafiltration failure (UFF). Our aim was to assess the relationship between effluent HGF with UF profile, free water transport (...

journal_title：BMC nephrology

authors： Bernardo AP,Oliveira JC,Santos O,Carvalho MJ,Cabrita A,Rodrigues A

更新日期：2014-12-17 00:00:00

abstract：BACKGROUND:This study aimed to compare clinical features and health-related quality of life (HRQoL) in the Chinese chronic kidney disease (CKD) 3 population and determined the necessity of the subdivision of CKD3 in Chinese patients with CKD. METHODS:Participants with stage 3 CKD (18-74 years of age) were recruited at...

journal_title：BMC nephrology

authors： Peng Z,Wang J,Yuan Q,Xiao X,Xu H,Xie Y,Wang W,Huang L,Zhong Y,Ao X,Zhang L,Zhao M,Tao L,Zhou Q,C-STRIDE study group.

更新日期：2017-10-13 00:00:00

abstract：BACKGROUND:Podocyte apoptosis is a major mechanism that leads to proteinuria in many kidney diseases. However, the concert mechanisms that cause podocyte apoptosis in these kidney diseases are not fully understood. RhoA is one of Rho GTPases that has been well studied and plays a key role in regulating cytoskeletal arc...

journal_title：BMC nephrology

authors： Huang Z,Zhang L,Chen Y,Zhang H,Yu C,Zhou F,Zhang Z,Jiang L,Li R,Ma J,Li Z,Lai Y,Lin T,Zhao X,Zhang Q,Zhang B,Ye Z,Liu S,Wang W,Liang X,Liao R,Shi W

更新日期：2016-07-07 00:00:00

abstract：BACKGROUND:There is a high prevalence of cognitive impairment in dialysis patients. The prevalence of cognitive impairment after kidney transplantation is unknown. METHODS:Study Design: Cross-sectional study. SETTING AND PARTICIPANTS:Single center study of prevalent kidney transplant recipients from a transplant clin...

journal_title：BMC nephrology

authors： Gupta A,Mahnken JD,Johnson DK,Thomas TS,Subramaniam D,Polshak T,Gani I,John Chen G,Burns JM,Sarnak MJ

更新日期：2017-05-12 00:00:00

abstract：BACKGROUND:Patients with end-stage renal disease (ESRD) exhibit a premature aging phenotype of immune system, which is recently concerned as a significant factor for increased risk of various morbidities. Nevertheless, there are few dates explicating the relevancy of T cell senescence to mortality. In this study, we pr...

journal_title：BMC nephrology

authors： Xiang F,Chen R,Cao X,Shen B,Chen X,Ding X,Zou J

更新日期：2020-07-13 00:00:00

abstract：BACKGROUND:Endothelial dysfunction occurs in patients with end-stage renal disease (ESRD) and is associated with increased cardiovascular morbidity and mortality. Asymmetric dimethylarginine (ADMA) contributes to endothelial dysfunction in ESRD. In the general population, angiotensin-converting enzyme (ACE) inhibitors ...

journal_title：BMC nephrology

authors： Gamboa JL,Pretorius M,Sprinkel KC,Brown NJ,Ikizler TA

更新日期：2015-10-22 00:00:00

abstract：BACKGROUND:Tolvaptan is a selective vasopressin receptor antagonist. Nitric Oxide (NO) promotes renal water and sodium excretion, but the effect is unknown in the nephron's principal cells. In a dose-response study, we measured the effect of tolvaptan on renal handling of water and sodium and systemic hemodynamics, dur...

journal_title：BMC nephrology

authors： Al Therwani S,Rosenbæk JB,Mose FH,Bech JN,Pedersen EB

更新日期：2017-03-13 00:00:00

abstract：:Chronic kidney disease (CKD) is an inherently systemic disease that refers to a long-term loss of kidney function. The progression of CKD has repercussions for other organs, leading to many kinds of extrarenal complications. Intensive studies are now being undertaken to reveal the risk factors and pathophysiological m...

journal_title：BMC nephrology

authors： Zou D,Wu W,He Y,Ma S,Gao J

更新日期：2018-10-22 00:00:00

abstract：BACKGROUND:Physical inactivity and sedentary behaviour (too much sitting) can contribute to renal dysfunction. However, the potential benefits of behavioural change (e.g. replacing sedentary behaviour with physical activity) on renal function are not well understood. We used isotemporal substitution to model potential ...

journal_title：BMC nephrology

authors： Kosaki K,Tanahashi K,Matsui M,Akazawa N,Osuka Y,Tanaka K,Dunstan DW,Owen N,Shibata A,Oka K,Maeda S

更新日期：2020-06-03 00:00:00

abstract：BACKGROUND:To measure health-related and care-related quality of life among informal caregivers of older people with end-stage kidney disease (ESKD), and to determine the association between caregiver quality of life and care recipient's treatment type. METHODS:A prospective cross-sectional study was conducted. Three ...

journal_title：BMC nephrology

authors： Shah KK,Murtagh FEM,McGeechan K,Crail SM,Burns A,Morton RL

更新日期：2020-05-04 00:00:00

abstract：BACKGROUND:Acute kidney injury (AKI) places a heavy burden on the healthcare system in China and is usually misdiagnosed. However, there are limited studies that have described the epidemiology and diagnosis of AKI in China. The aim of this study was to describe the incidence and diagnosis of AKI in hospitalized adult ...

journal_title：BMC nephrology

authors： Cheng X,Wu B,Liu Y,Mao H,Xing C

更新日期：2017-06-24 00:00:00

abstract：BACKGROUND:Accurately determining renal function is essential for clinical management of HIV patients. Classically, it has been evaluated by estimating glomerular filtration rate (eGFR) with the MDRD-equation, but today there is evidence that the new Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation ...

journal_title：BMC nephrology

authors： Cristelli MP,Cofán F,Rico N,Trullàs JC,Manzardo C,Agüero F,Bedini JL,Moreno A,Oppenheimer F,Miro JM,CKD-H. Clinic Investigators.

更新日期：2017-02-10 00:00:00

abstract：BACKGROUND:Bordetella pertussis infection is a known trigger of atypical hemolytic uremic syndrome (HUS). For patients suspected of having atypical HUS, prompt plasma exchange/infusion (PE/PI) or eculizumab (ECZ) treatment is recommended. CASE PRESENTATION:We report a 1-month-old female infant who was admitted with a ...

journal_title：BMC nephrology

authors： Saida K,Ogura M,Kano Y,Ishimori S,Yoshikawa T,Nagata H,Sato M,Kamei K,Ishikura K

更新日期：2018-12-17 00:00:00

abstract：BACKGROUND:Indoleamine 2, 3-dioxygenase (IDO) is an immunomodulatory molecule that has been implicated in several biological processes. Although IDO has been linked with some renal diseases, its role in renal fibrosis is still unclear. Because IDO may be modulated by TGF-β1, a potent fibrogenic molecule, we hypothesize...

journal_title：BMC nephrology

authors： Matheus LHG,Simão GM,Amaral TA,Brito RBO,Malta CS,Matos YST,Santana AC,Rodrigues GGC,Albejante MC,Bach EE,Dalboni MA,Camacho CP,Dellê H

更新日期：2017-09-06 00:00:00

abstract：BACKGROUND:Cancer-related thrombotic microangiopathy (CR-TMA) is a rare entity associated with a dismal prognosis. Usually, CR-TMA is associated with mucin-producing carcinomas among which stomach, breast, prostate, lung and pancreas tumours are the most frequent. CASES PRESENTATION:We describe for the first time thre...

journal_title：BMC nephrology

authors： de Nattes T,Moreau-Grangé L,Vezzosi D,Hadoux J,Hie M,Guerrot D,Grangé S

更新日期：2020-01-30 00:00:00

abstract：BACKGROUND:Bilateral emphysematous pyelonephritis is a life threatening condition usually occurring in diabetics. Management of this condition has traditionally been aggressive and surgery is considered mandatory. However, this is itself a hazardous intervention in a septic, unstable patient with circulatory or liver f...

journal_title：BMC nephrology

authors： Flores G,Nellen H,Magaña F,Calleja J

更新日期：2002-06-03 00:00:00

abstract：BACKGROUND:Levetiracetam is a frequently used drug in the therapy of partial onset, myoclonic and generalized tonic-clonic seizures. The main route of elimination is via the kidneys, which eliminate 66% of the unchanged drug as well as 24% as inactive metabolite that stems from enzymatic hydrolysis. Therefore dose adju...

journal_title：BMC nephrology

authors： Bahte SK,Hiss M,Lichtinghagen R,Kielstein JT

更新日期：2014-04-16 00:00:00

abstract：BACKGROUND:Chronic kidney disease (CKD) with edema is a common clinical problem resulting from defects in water and solute excretion. Furosemide is the drug of choice for treatment. In theory, good perfusion and albumin are required for the furosemide to be secreted at the tubular lumen. Thus, in the situation of low g...

journal_title：BMC nephrology

authors： Phakdeekitcharoen B,Boonyawat K

更新日期：2012-08-29 00:00:00

abstract：BACKGROUND:Sclerostin is a paracrine acting factor, which is expressed in the osteocytes and articular chondrocytes. Sclerostin decreases the osteoblast-related bone formation through the inhibition of the Wnt/β-catenin pathway. Osteocytes also express the Calcium sensing receptor which is a target for cinacalcet. The ...

journal_title：BMC nephrology

authors： Kuczera P,Adamczak M,Więcek A

更新日期：2016-11-15 00:00:00