High serum bicarbonate level within the normal range prevents the progression of chronic kidney disease in elderly chronic kidney disease patients.

abstract：BACKGROUND:Abdominal aortic calcification assessed by X-ray is recommended to evaluate vascular calcification in dialysis patients. It has been shown that abdominal aortic calcification score (AACS) is a predictor of adverse outcomes in hemodialysis patients, but evidence regarding its prognostic value in peritoneal di...

journal_title：BMC nephrology

authors： Ma D,Yan H,Yang X,Yu Z,Ni Z,Fang W

更新日期：2020-04-30 00:00:00

abstract：BACKGROUND:Physical activity (PA) is exceptionally low amongst the haemodialysis (HD) population, and physical inactivity is a powerful predictor of mortality, making it a prime focus for intervention. Objective measurement of PA using accelerometers is increasing, but standard reporting guidelines essential to effecti...

journal_title：BMC nephrology

authors： Young HML,Orme MW,Song Y,Dungey M,Burton JO,Smith AC,Singh SJ

更新日期：2019-12-04 00:00:00

abstract：BACKGROUND:To assess whether serum osteoprotegerin (OPG) and/or fetuin-A predict mortality and cardiovascular (CV) morbidity and mortality in hemodialysis patients. METHODS:Multicenter, observational, prospective study that included 220 hemodialysis patients followed up for up to 6 years. Serum OPG and fetuin-A levels...

journal_title：BMC nephrology

authors： Collado S,Coll E,Nicolau C,Azqueta M,Pons M,Cruzado JM,de la Torre B,Deulofeu R,Mojal S,Pascual J,Cases A

更新日期：2017-09-07 00:00:00

abstract：BACKGROUND:Early preparation for renal replacement therapy (RRT) is recommended for patients with advanced chronic kidney disease (CKD), yet many patients initiate RRT urgently and/or are inadequately prepared. METHODS:We conducted audio-recorded, qualitative, directed telephone interviews of nephrology health care pr...

journal_title：BMC nephrology

authors： Greer RC,Ameling JM,Cavanaugh KL,Jaar BG,Grubbs V,Andrews CE,Ephraim P,Powe NR,Lewis J,Umeukeje E,Gimenez L,James S,Boulware LE

更新日期：2015-03-28 00:00:00

abstract：BACKGROUND:The magnitude of renal function recovery after kidney donation differs in donors with a heterogeneous background. Preoperative assessment of candidates with potentially unfavorable renal functional compensation is critical when baseline kidney function is marginal. We explored the significance of preserved k...

journal_title：BMC nephrology

authors： Shinoda K,Morita S,Akita H,Tamaki S,Takahashi R,Kono H,Asanuma H,Kikuchi E,Jinzaki M,Nakagawa K,Oya M

更新日期：2019-02-08 00:00:00

abstract：BACKGROUND:Almost all cases of renal hydatid cysts need surgical intervention for treatment. We report a case of isolated renal hydatid cyst treated successfully only with medical therapy. CASE PRESENTATION:This case is a 79-year-old veterinarian presented with right flank pain, hydatiduria and positive echinococcus g...

journal_title：BMC nephrology

authors： Moghtadaie A,Yazdi SAM,Mohraz M,Asefi H,Razeghi E

更新日期：2020-10-08 00:00:00

abstract：BACKGROUND:Sclerostin is a paracrine acting factor, which is expressed in the osteocytes and articular chondrocytes. Sclerostin decreases the osteoblast-related bone formation through the inhibition of the Wnt/β-catenin pathway. Osteocytes also express the Calcium sensing receptor which is a target for cinacalcet. The ...

journal_title：BMC nephrology

authors： Kuczera P,Adamczak M,Więcek A

更新日期：2016-11-15 00:00:00

abstract：BACKGROUND:Accurate estimation of glomerular filtration rate (GFR) is important for diagnosis and risk stratification in chronic kidney disease and for selection of living donors. Ethnic differences have required correction factors in the originally developed creatinine-based GFR estimation equations for populations ar...

journal_title：BMC nephrology

authors： Kumar V,Yadav AK,Yasuda Y,Horio M,Kumar V,Sahni N,Gupta KL,Matsuo S,Kohli HS,Jha V

更新日期：2018-02-01 00:00:00

abstract：BACKGROUND:Use of serum creatinine to estimate GFR may lead to underestimation of the association between self-reported frailty and kidney function. Our objectives were to evaluate the association of measured GFR (mGFR) with self-reported frailty among patients with CKD and to determine whether self-reported frailty wa...

journal_title：BMC nephrology

authors： Delgado C,Grimes BA,Glidden DV,Shlipak M,Sarnak MJ,Johansen KL

更新日期：2015-12-09 00:00:00

abstract：BACKGROUND:Transfusion patterns are not well characterized in non-dialysis (ND) chronic kidney disease (CKD) patients. This study describes the proportion of patients transfused, units of blood transfused and trigger-hemoglobin (Hb) levels for transfusions in severe anemic, ND-CKD patients in routine practice. METHODS...

journal_title：BMC nephrology

authors： Fox KM,Yee J,Cong Z,Brooks JM,Petersen J,Lamerato L,Gandra SR

更新日期：2012-01-24 00:00:00

abstract：BACKGROUND:Variants in CUBN, the gene encoding cubilin, a proximal tubular transport protein, have been associated with albuminuria and vitamin B12 (B12) deficiency. We hypothesized that low levels of B12 would be associated with albuminuria in a population-based cohort. METHODS:We analyzed participants from the Frami...

journal_title：BMC nephrology

authors： McMahon GM,Hwang SJ,Tanner RM,Jacques PF,Selhub J,Muntner P,Fox CS

更新日期：2015-02-02 00:00:00

abstract：BACKGROUND:Corticosteroids are widely used to reduce the urine protein levels of patients with immunoglobulin A nephropathy (IgAN). However, their potential preventive effects on end-stage kidney disease (ESKD) are unclear. METHODS:We previously performed a large-scale, long-term multicenter cohort study of patients w...

journal_title：BMC nephrology

authors： Tsunoda R,Usui J,Hoshino J,Fujii T,Suzuki S,Takaichi K,Ubara Y,Yamagata K

更新日期：2018-09-06 00:00:00

abstract：INTRODUCTION:Urinary biomarkers of kidney injury are presumed to reflect renal tubular damage. However, their concentrations may be influenced by other factors, such as hematuria or pyuria. We sought to examine what non-injury related urinalysis factors are associated with urinary biomarker levels. METHODS:We examined...

journal_title：BMC nephrology

authors： Nadkarni GN,Coca SG,Meisner A,Patel S,Kerr KF,Patel UD,Koyner JL,Garg AX,Philbrook HT,Edelstein CL,Shlipak M,El-Khoury J,Parikh CR,TRIBE-AKI Consortium Investigators.

更新日期：2017-07-06 00:00:00

abstract：BACKGROUND:A classification tree model (CT-PIRP) was developed in 2013 to predict the annual renal function decline of patients with chronic kidney disease (CKD) participating in the PIRP (Progetto Insufficienza Renale Progressiva) project, which involves thirteen Nephrology Hospital Units in Emilia-Romagna (Italy). Th...

journal_title：BMC nephrology

authors： Gibertoni D,Rucci P,Mandreoli M,Corradini M,Martelli D,Russo G,Mancini E,Santoro A

更新日期：2019-05-17 00:00:00

abstract：BACKGROUND:Major Depressive Disorder (MDD) can lead to adverse cardiovascular outcomes in patients with chronic kidney disease (CKD). Although one of the proposed mechanisms is heightened platelet activation, effects of MDD and its treatment with a selective serotonin reuptake inhibitor (SSRI) on platelet function in p...

journal_title：BMC nephrology

authors： Jain N,Wan F,Kothari M,Adelodun A,Ware J,Sarode R,Hedayati SS

更新日期：2019-10-29 00:00:00

abstract：BACKGROUND:Interleukin 17 is a proinflammatory cytokine involved in immune response after allograft transplantation. IL-17 family of proinflammatory cytokines includes IL-17A and IL-17F. Previous studies have demonstrated that the rs2275913 IL17A and the rs11465553 IL17F gene polymorphism are associated with kidney all...

journal_title：BMC nephrology

authors： Domanski L,Kłoda K,Patrzyk M,Wisniewska M,Safranow K,Sienko J,Sulikowski T,Staniszewska M,Pawlik A

更新日期：2019-04-08 00:00:00

abstract：BACKGROUND:Estimates of the incidence of glomerulonephritis (GN) and end-stage renal disease (ESRD) in an Iraqi population are compared with the United States (US) and Jordan. METHODS:The study set consist of renal biopsies performed in 2012 and 2013 in the Kurdish provinces of Northern Iraq. The age specific and age ...

journal_title：BMC nephrology

authors： Ali AA,Sharif DA,Almukhtar SE,Abd KH,Saleem ZSM,Hughson MD

更新日期：2018-10-11 00:00:00

abstract：BACKGROUND:Stage 5 chronic kidney disease (CKD-5) patients on haemodialysis (HD) are at high risk of accidental falls. Previous research has shown that frailty is one of the primary contributors to the increased risk of falling in this clinical population. However, HD patients often present with abnormalities of cardio...

journal_title：BMC nephrology

authors： Zanotto T,Mercer TH,van der Linden ML,Rush R,Traynor JP,Petrie CJ,Doyle A,Chalmers K,Allan N,Shilliday I,Koufaki P

更新日期：2020-03-14 00:00:00

abstract：BACKGROUND:Chronic kidney disease (CKD) is increasing worldwide and early education to improve adherence to self-management is a key strategy to slow CKD progression. The use of the internet and mobile phone technologies (mHealth) to support patients is considered an effective tool in many other chronic disease populat...

journal_title：BMC nephrology

authors： Bonner A,Gillespie K,Campbell KL,Corones-Watkins K,Hayes B,Harvie B,Kelly JT,Havas K

更新日期：2018-02-02 00:00:00

abstract：BACKGROUND:Local renal ischemia is regarded as an important factor in the development of contrast-induced nephropathy (CIN). Mannose-binding lectin (MBL) is involved in the tissue damage during experimental ischemia/reperfusion injury of the kidneys. The aim of the present study was to investigate the association of MB...

journal_title：BMC nephrology

authors： Osthoff M,Piezzi V,Klima T,Christ A,Marana I,Hartwiger S,Breidthardt T,Marenzi G,Trendelenburg M,Mueller C

更新日期：2012-09-03 00:00:00

abstract：BACKGROUND:Occurrence of cardiovascular disease (CVD) in the setting of chronic kidney disease (CKD) can be described as a "cruel alliance", with CVD responsible for about half of all deaths among CKD patients. Chronic kidney disease patients are more likely to die from CVD than progress to end stage kidney disease (ES...

journal_title：BMC nephrology

authors： Oguntola SO,Hassan MO,Duarte R,Vachiat A,Manga P,Naicker S

更新日期：2019-10-30 00:00:00

abstract：BACKGROUND:Experimental studies showed that 25-hydroxy-vitamin D [25(OH)D] deficiency (defined as 25-hydroxy-vitamin D < 15 ng/ml) has been associated with CKD progression. Patients with IgA nephropathy have an exceptionally high rate of severe 25(OH)D deficiency; however, it is not known whether this deficiency is a r...

journal_title：BMC nephrology

authors： Li XH,Huang XP,Pan L,Wang CY,Qin J,Nong FW,Luo YZ,Wu Y,Huang YM,Peng X,Yang ZH,Liao YH

更新日期：2016-11-02 00:00:00

abstract：BACKGROUND:Group A streptococcus (GAS) is an etiological agent for the immune mediated sequela post streptococcal glomerulonephritis (PSGN). In some populations PSGN is recognized as a risk factor for chronic kidney disease (CKD) and end-stage renal disease (ESRD). It was found that a significantly greater proportion o...

journal_title：BMC nephrology

authors： Karmarkar MG,Hule GP,Hase NK,Mehta PR,Walter SR,Sriprakash KS

更新日期：2013-05-06 00:00:00

abstract：BACKGROUND:Renal involvement in patients with chronic hepatitis C virus infection has been suggested to be due to a variety of immunological processes. However, the precise mechanism by which the kidneys are damaged in these patients is still unclear. CASE PRESENTATION:A 66 year old man presented with the sudden onset...

journal_title：BMC nephrology

authors： Ohsawa I,Uehara Y,Hashimoto S,Endo M,Fujita T,Ohi H

更新日期：2003-08-29 00:00:00

abstract：BACKGROUND:Anaemia of chronic kidney disease increases the risk of death and adverse events, but can be managed using erythropoiesis stimulating agents (ESAs). However, recent evidence suggests that targeting a higher haemoglobin concentration ([Hb]) increases mortality risk, and both higher [Hb] targets and ESA doses ...

journal_title：BMC nephrology

authors： McMahon LP,Cai MX,Baweja S,Holt SG,Kent AB,Perkovic V,Leikis MJ,Becker GJ

更新日期：2012-06-15 00:00:00

abstract：BACKGROUND:This study was designed to assess the prevalence of chronic kidney disease (CKD) and associated risk factors among the Chinese population in Taian, China. METHODS:A primary care-based cross-sectional study was conducted in Taian, China, from September to December 2012. Participants selected by a multi-stage...

journal_title：BMC nephrology

authors： Xue L,Lou Y,Feng X,Wang C,Ran Z,Zhang X

更新日期：2014-12-21 00:00:00

abstract：BACKGROUND:Several equations have been developed to estimate glomerular filtration rate (eGFR). The common equations used were derived from populations predominantly comprised of Caucasians with chronic kidney disease (CKD). Some of the equations provide a correction factor for African-Americans due to their relatively...

journal_title：BMC nephrology

authors： Omuse G,Maina D,Mwangi J,Wambua C,Kanyua A,Kagotho E,Amayo A,Ojwang P,Erasmus R

更新日期：2017-12-20 00:00:00

abstract：BACKGROUND:Little is known about the changes in disease makers and risk factors in patients with chronic kidney disease (CKD) under nephrological care in Africa. This study aimed to evaluate the baseline level of markers of CKD and their 12-month time-trend in newly referred patients in a tertiary hospital in Cameroon....

journal_title：BMC nephrology

authors： Patrice HM,Pascal KA,François KF,Hilaire D,Solange DM,Gloria AE,Pierre CS

更新日期：2020-03-18 00:00:00

abstract：BACKGROUND:A previous cohort study indicated a significant association of lower baseline level of physical activity in hemodialysis patients with elevated risks of mortality. However, there have been no reports regarding the association between changes in physical activity over time and mortality in hemodialysis patien...

journal_title：BMC nephrology

authors： Shimoda T,Matsuzawa R,Yoneki K,Harada M,Watanabe T,Matsumoto M,Yoshida A,Takeuchi Y,Matsunaga A

更新日期：2017-05-08 00:00:00

abstract：BACKGROUND:Awareness of the spectrum of clinical manifestations of systemic lupus erythematosus (SLE), especially uncommon changes, is essential for diagnosis and effective management of patients. CASE PRESENTATION:A 26-year-old Chinese man with SLE initially manifested cutaneous papulonodular mucinosis and developed ...

journal_title：BMC nephrology

authors： Su X,Qiao X,Li J,Gao L,Wang C,Wang L

更新日期：2017-02-01 00:00:00