Transfusion burden in non-dialysis chronic kidney disease patients with persistent anemia treated in routine clinical practice: a retrospective observational study.

abstract：BACKGROUND:Patients with diabetes and chronic kidney disease (CKD) are a complex subset of the growing number of patients with diabetes, due to multi-morbidity. Gaps between recommended and received care for diabetes and chronic kidney disease (CKD) are evident despite promulgation of guidelines. Here, we document gaps...

journal_title：BMC nephrology

authors： Lo C,Teede H,Fulcher G,Gallagher M,Kerr PG,Ranasinha S,Russell G,Walker R,Zoungas S

更新日期：2017-02-28 00:00:00

abstract：BACKGROUND:Rehabilitation effects of exercise training on adults with chronic kidney disease (CKD) have been generally recognised; however, the effects of exercise training on proteinuria have been underexplored. Our aim was to explore the effects of exercise training on proteinuria in adult CKD patients without renal ...

journal_title：BMC nephrology

authors： Yang L,Wu X,Wang Y,Wang C,Hu R,Wu Y

更新日期：2020-05-11 00:00:00

abstract：BACKGROUND:Corticosteroids are widely used to reduce the urine protein levels of patients with immunoglobulin A nephropathy (IgAN). However, their potential preventive effects on end-stage kidney disease (ESKD) are unclear. METHODS:We previously performed a large-scale, long-term multicenter cohort study of patients w...

journal_title：BMC nephrology

authors： Tsunoda R,Usui J,Hoshino J,Fujii T,Suzuki S,Takaichi K,Ubara Y,Yamagata K

更新日期：2018-09-06 00:00:00

abstract：BACKGROUND:A marked reduction in serum levels of bioactive insulin-like growth factor-I (IGF-I) has been observed in fasting hemodialysis (HD) patients during a 4-h HD session. The aim of the present study was to investigate the beneficial effect of hyperinsulinemia during HD on bioactive IGF-I and inflammatory biomark...

journal_title：BMC nephrology

authors： Reinhard M,Frystyk J,Jespersen B,Bjerre M,Christiansen JS,Flyvbjerg A,Ivarsen P

更新日期：2013-04-04 00:00:00

abstract：BACKGROUND:Patients with pre-existing impaired renal function are prone to develop acute contrast media induced nephropathy (CIN). Neutrophil gelatinase-associated lipocalin (NGAL), a new biomarker predictive for acute kidney injury (AKI), has been shown to be useful for earlier diagnosis of CIN; however, urinary NGAL ...

journal_title：BMC nephrology

authors： Schilcher G,Ribitsch W,Otto R,Portugaller RH,Quehenberger F,Truschnig-Wilders M,Zweiker R,Stiegler P,Brodmann M,Weinhandl K,Horina JH

更新日期：2011-08-17 00:00:00

abstract：BACKGROUND:Chronic active antibody-mediated rejection is a major etiology of graft loss in renal transplant recipients. However, there is no consensus on the optimal treatment strategies. METHODS:Computerized records from Taichung Veterans General Hospital were collected to identify renal transplant biopsies performed...

journal_title：BMC nephrology

authors： Chiu HF,Wen MC,Wu MJ,Chen CH,Yu TM,Chuang YW,Huang ST,Tsai SF,Lo YC,Ho HC,Shu KH

更新日期：2020-01-06 00:00:00

abstract：BACKGROUND:The effect of chronic hepatitis B virus (HBV) infection on the risk of chronic kidney disease (CKD) is controversial. We examined the prospective association between hepatitis B surface antigen (HBsAg) serology status and incident CKD in a large cohort of men and women. METHODS:Cohort study of 299,913 adult...

journal_title：BMC nephrology

authors： Hong YS,Ryu S,Chang Y,Caínzos-Achirica M,Kwon MJ,Zhao D,Shafi T,Lazo M,Pastor-Barriuso R,Shin H,Cho J,Guallar E

更新日期：2018-12-11 00:00:00

abstract：BACKGROUND:The aim of the study was to assess the association between chronic kidney disease (CKD) and obesity in predicting CKD among Chinese adults, distinguishing between 5 different adiposity indices: visceral fat index (VFI), percentage body fat (PBF), body mass index (BMI), waist circumference (WC) and waist-to-h...

journal_title：BMC nephrology

authors： Dong Y,Wang Z,Chen Z,Wang X,Zhang L,Nie J,Zheng C,Wang J,Shao L,Tian Y,Gao R

更新日期：2018-02-17 00:00:00

abstract：BACKGROUND:Whether persistent hematuria in patients with antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) during clinical remission reflects active disease or chronic glomerular injury is uncertain. This study aimed to investigate the significance of persistent hematuria during clinical remission ...

journal_title：BMC nephrology

authors： Lv L,Chang DY,Li ZY,Chen M,Hu Z,Zhao MH

更新日期：2017-12-06 00:00:00

abstract：BACKGROUND:There is limited evidence on the relationship between social support and renal outcomes in African Americans. We sought to determine the association of social support with prevalent chronic kidney disease (CKD) and kidney function decline in an African American cohort. We also examined whether age modifies t...

journal_title：BMC nephrology

authors： Hall RK,Davenport CA,Sims M,Colón-Emeric C,Washington T,St Clair Russell J,Pendergast J,Bhavsar N,Scialla J,Tyson CC,Wang W,Min YI,Young B,Boulware LE,Diamantidis CJ

更新日期：2019-07-15 00:00:00

abstract：BACKGROUND:Aluminium (Al) toxicity was frequent in the 1980s in patients ingesting Al containing phosphate binders (Alucaps) whilst having HD using water potentially contaminated with Al. The aim of this study was to determine the risk of Al toxicity in HD patients receiving Alucaps but never exposed to contaminated di...

journal_title：BMC nephrology

authors： Pepper R,Campbell N,Yaqoob MM,Roberts NB,Fan SL

更新日期：2011-10-12 00:00:00

abstract：BACKGROUND:Use of serum creatinine to estimate GFR may lead to underestimation of the association between self-reported frailty and kidney function. Our objectives were to evaluate the association of measured GFR (mGFR) with self-reported frailty among patients with CKD and to determine whether self-reported frailty wa...

journal_title：BMC nephrology

authors： Delgado C,Grimes BA,Glidden DV,Shlipak M,Sarnak MJ,Johansen KL

更新日期：2015-12-09 00:00:00

abstract：BACKGROUND:The magnitude of renal function recovery after kidney donation differs in donors with a heterogeneous background. Preoperative assessment of candidates with potentially unfavorable renal functional compensation is critical when baseline kidney function is marginal. We explored the significance of preserved k...

journal_title：BMC nephrology

authors： Shinoda K,Morita S,Akita H,Tamaki S,Takahashi R,Kono H,Asanuma H,Kikuchi E,Jinzaki M,Nakagawa K,Oya M

更新日期：2019-02-08 00:00:00

abstract：BACKGROUND:Patients with chronic kidney diseases (CKD) on haemodialysis (HD) have high morbidity and mortality rates, which are also due to the inherent risks associated with nephropathy. Non-adherence (NA) to the different demands of the treatment can have consequences for the outcome of patients undergoing HD; nevert...

journal_title：BMC nephrology

authors： Dantas LGG,de Seixas Rocha M,Junior JAM,Paschoalin EL,Paschoalin SRKP,Sampaio Cruz CM

更新日期：2019-11-06 00:00:00

abstract：BACKGROUND:This study was aimed at determining the outcome and examining the association between comorbidities and mortality after intracerebral hemorrhage in chronic dialysis patients. METHODS:We used the Taiwan National Health Insurance Research Database and enrolled patients who underwent maintenance dialysis betwe...

journal_title：BMC nephrology

authors： Lin CY,Chien CC,Chen HA,Su FM,Wang JJ,Wang CC,Chu CC,Lin YJ

更新日期：2014-11-27 00:00:00

abstract：BACKGROUND:Diabetic nephropathy (DN) is a primary complication of diabetes mellitus (DM). The pathology of DN is still vague, and diagnostic accuracy is not enough. This study was performed to identify miRNAs and genes that have possibilities of being used as therapeutic targets for DN in type 2 DM. METHODS:Human miRN...

journal_title：BMC nephrology

authors： Yu Y,Jia YY,Wang M,Mu L,Li HJ

更新日期：2021-01-12 00:00:00

abstract：BACKGROUND:In a recent study we demonstrated that low birth weight (LBW) was associated with increased risk of progressive IgA nephropathy (IgAN). In the present study we investigate whether this could be explained by differences in glomerular morphological parameters. METHODS:The Medical Birth Registry of Norway has ...

journal_title：BMC nephrology

authors： Ruggajo P,Leh S,Svarstad E,Marti HP,Vikse BE

更新日期：2018-10-22 00:00:00

abstract：BACKGROUND:Physical inactivity and sedentary behaviour (too much sitting) can contribute to renal dysfunction. However, the potential benefits of behavioural change (e.g. replacing sedentary behaviour with physical activity) on renal function are not well understood. We used isotemporal substitution to model potential ...

journal_title：BMC nephrology

authors： Kosaki K,Tanahashi K,Matsui M,Akazawa N,Osuka Y,Tanaka K,Dunstan DW,Owen N,Shibata A,Oka K,Maeda S

更新日期：2020-06-03 00:00:00

abstract：BACKGROUND:Autosomal dominant polycystic kidney disease (ADPKD) is mainly characterised by the development and enlargement of renal cysts that lead to end-stage renal disease (ESRD) in adult patients. Other clinical manifestations of this pathology include hypertension, haematuria, abdominal pain, cardiovascular system...

journal_title：BMC nephrology

authors： Magistroni R,Mangolini A,Guzzo S,Testa F,Rapanà MR,Mignani R,Russo G,di Virgilio F,Aguiari G

更新日期：2019-09-13 00:00:00

abstract：BACKGROUND:The clinical outcomes of ST-segment elevation myocardial infarction (STEMI) are poor in patients with renal insufficiency. This study investigated changes in the likelihood that patients received optimal medical care throughout the entire process of myocardial infarction management, on the basis of their glo...

journal_title：BMC nephrology

authors： Choi JS,Kim CS,Bae EH,Ma SK,Jeong MH,Kim YJ,Cho MC,Kim CJ,Kim SW

更新日期：2012-09-11 00:00:00

abstract：BACKGROUND:Complementary and Alternative Medicines (CAMs) are increasingly practiced in the general population; it is estimated that over 30% of patients with chronic diseases use CAMs on a regular basis. CAMs are also used in hospital settings, suggesting a growing interest in individualized therapies. One potential f...

journal_title：BMC nephrology

authors： Ferraresi M,Clari R,Moro I,Banino E,Boero E,Crosio A,Dayne R,Rosset L,Scarpa A,Serra E,Surace A,Testore A,Colombi N,Piccoli BG

更新日期：2013-06-21 00:00:00

abstract：BACKGROUND:Emerging evidence of psychosocial problems in CKD patients has led to an acceptance that a focus on the emotional wellbeing of the patient should be included in the provision of comprehensive CKD care. It is unclear if an increased attention for psychosocial needs in guidelines and policy documents has led t...

journal_title：BMC nephrology

authors： Seekles ML,Ormandy P,Coyne E

更新日期：2019-03-21 00:00:00

abstract：BACKGROUND:Metabolic acidosis leads to chronic kidney disease (CKD) progression. The guidelines recommend a lower limit of serum bicarbonate level, but no upper limit. For serum bicarbonate level to be clinically useful as a therapeutic target marker, it is necessary to investigate the target serum bicarbonate level wi...

journal_title：BMC nephrology

authors： Kanda E,Ai M,Yoshida M,Kuriyama R,Shiigai T

更新日期：2013-01-09 00:00:00

abstract：BACKGROUND:The short-term efficacy of tolvaptan in patients with autosomal dominant polycystic kidney disease (ADPKD) has been demonstrated across several phase 3 trials, while the ADPKD Outcomes Model (ADPKD-OM) represents a validated approach to predict natural disease progression over a lifetime horizon. This study ...

journal_title：BMC nephrology

authors： Bennett H,McEwan P,Hamilton K,O'Reilly K

更新日期：2019-04-23 00:00:00

abstract：BACKGROUND:The aims of this study are to find the prevalence of potential drug-drug interactions (DDIs) in patients with Hemodialysis and identify factors associated with these interactions if present. METHODS:The study was an observational- retrospective cohort study that was conducted in ten hemodialysis units in th...

journal_title：BMC nephrology

authors： Al-Ramahi R,Raddad AR,Rashed AO,Bsharat A,Abu-Ghazaleh D,Yasin E,Shehab O

更新日期：2016-07-26 00:00:00

abstract：BACKGROUND:Although chronic kidney disease (CKD) affects a growing number of people, epidemiologic data on incident CKD in the general population are scarce. Screening strategies to increase early CKD detection have been developed. METHODS:From a community-based sample of 4,409 individuals residing in a well-defined g...

journal_title：BMC nephrology

authors： Ayav C,Beuscart JB,Briançon S,Duhamel A,Frimat L,Kessler M

更新日期：2016-11-15 00:00:00

abstract：BACKGROUND:Fibrillary glomerulonephritis (FGN) is distinguished from amyloidosis by thicker fibrils and the lack of staining with histochemical dyes typically reactive with amyloid. However, congophilic FGN has been proposed recently and adding laser microdissection followed by mass spectrometry (LMD/MS) to conventiona...

journal_title：BMC nephrology

authors： Adachi M,Kitamura M,Muta K,Maekawa A,Uramatsu T,Tadokoro M,Funakoshi S,Hisano S,Kuwahara N,Shimizu A,Mukae H,Nishino T

更新日期：2020-05-24 00:00:00

abstract：BACKGROUND:MicroRNAs have been demonstrated to play an important role in the pathogenesis of diabetic nephropathy (DN). In this study, we investigated both the repertoire of miRNAs in the kidneys of patients with DN and their potential regulatory role in inflammation-mediated glomerular endothelial injury. METHODS:The...

journal_title：BMC nephrology

authors： Huang Y,Liu Y,Li L,Su B,Yang L,Fan W,Yin Q,Chen L,Cui T,Zhang J,Lu Y,Cheng J,Fu P,Liu F

更新日期：2014-09-02 00:00:00

abstract：BACKGROUND:This study describes chronic kidney disease of uncertain aetiology (CKDu), which cannot be attributed to diabetes, hypertension or other known aetiologies, that has emerged in the North Central region of Sri Lanka. METHODS:A cross-sectional study was conducted, to determine the prevalence of and risk factor...

journal_title：BMC nephrology

authors： Jayatilake N,Mendis S,Maheepala P,Mehta FR,CKDu National Research Project Team.

更新日期：2013-08-27 00:00:00

abstract：BACKGROUND:Multiple factors influence timing of dialysis initiation. The impact of supply of nephrology workforce on timing and incidence of dialysis initiation is not well known. METHODS:We determined the number of pediatric and adult nephrologists in each state using data from the American Medical Association and Am...

journal_title：BMC nephrology

authors： Ku E,Johansen KL,Portale AA,Grimes B,Hsu CY

更新日期：2015-01-15 00:00:00