Treatment of chronic active antibody-mediated rejection in renal transplant recipients - a single center retrospective study.

abstract：BACKGROUND:Occurrence of cardiovascular disease (CVD) in the setting of chronic kidney disease (CKD) can be described as a "cruel alliance", with CVD responsible for about half of all deaths among CKD patients. Chronic kidney disease patients are more likely to die from CVD than progress to end stage kidney disease (ES...

journal_title：BMC nephrology

authors： Oguntola SO,Hassan MO,Duarte R,Vachiat A,Manga P,Naicker S

更新日期：2019-10-30 00:00:00

abstract：BACKGROUND:Glomerular filtration rate (GFR) is the best index of renal function, but age, gender and ethnicity can putatively affect its values. The aim of this study was to establish reference values for GFR in healthy Brazilian subjects while taking these factors into account. METHODS:In this cross-sectional study, ...

journal_title：BMC nephrology

authors： Soares AA,Prates AB,Weinert LS,Veronese FV,de Azevedo MJ,Silveiro SP

更新日期：2013-02-28 00:00:00

abstract：BACKGROUND:Klotho is a transmembrane protein acting as a co-receptor for FGF-23 and thus exerts clinical actions on mineral metabolism. The association of secreted Klotho with outcomes in CKD patients is unclear. This study examined the relation between plasma Klotho and cardiovascular events in dialysis patients, acco...

journal_title：BMC nephrology

authors： Memmos E,Sarafidis P,Pateinakis P,Tsiantoulas A,Faitatzidou D,Giamalis P,Vasilikos V,Papagianni A

更新日期：2019-06-11 00:00:00

abstract：BACKGROUND:Both dialysis facilities and hospitals are accountable for 30-day hospital readmissions among U.S. hemodialysis patients. We examined the association of post-hospitalization processes of care at hemodialysis facilities with pulmonary edema-related and other readmissions. METHODS:In a retrospective cohort co...

journal_title：BMC nephrology

authors： Plantinga LC,Masud T,Lea JP,Burkart JM,O'Donnell CM,Jaar BG

更新日期：2018-07-31 00:00:00

abstract：BACKGROUND:Although chronic kidney disease (CKD) affects a growing number of people, epidemiologic data on incident CKD in the general population are scarce. Screening strategies to increase early CKD detection have been developed. METHODS:From a community-based sample of 4,409 individuals residing in a well-defined g...

journal_title：BMC nephrology

authors： Ayav C,Beuscart JB,Briançon S,Duhamel A,Frimat L,Kessler M

更新日期：2016-11-15 00:00:00

abstract：BACKGROUND:End-Stage Renal disease (ESRD) is associated with increased morbidity and mortality. We assessed the occurrence, time-trend and determinants of fatal outcomes of haemodialysis-treated ESRD patients over a 10-year period in a major referral hospital in Cameroon. METHODS:Medical records of ESRD patients who s...

journal_title：BMC nephrology

authors： Halle MP,Ashuntantang G,Kaze FF,Takongue C,Kengne AP

更新日期：2016-11-03 00:00:00

abstract：BACKGROUND:Glucocorticoids (GCs) are frequently used to treat glomerular diseases but are associated with multiple adverse effects including hypothalamic-pituitary-adrenal axis inhibition that can lead to adrenal insufficiency (AI) on withdrawal. There is no agreed GC tapering strategy to minimise this risk. METHODS:T...

journal_title：BMC nephrology

authors： Karangizi AHK,Al-Shaghana M,Logan S,Criseno S,Webster R,Boelaert K,Hewins P,Harper L

更新日期：2019-05-06 00:00:00

abstract：BACKGROUND:Cool dialysate is often recommended for prevention of intra-dialytic hypotensive episodes in maintenance hemodialysis (HD) patients. However, its effect on toxin removal is not studied. It is known that inter-compartmental resistance is the main barrier for toxin removal. Cool dialysate can potentially incre...

journal_title：BMC nephrology

authors： Maheshwari V,Lau T,Samavedham L,Rangaiah GP

更新日期：2015-02-27 00:00:00

abstract：BACKGROUND:Anaemia is common in haemodialysis (HD) patients and associated with significant morbidity and mortality. Intravenous (IV) iron combined with erythropoiesis-stimulating agents (ESA) is the mainstay treatment of anaemia in these patients. The comparative efficacy and risk of adverse events with IV iron prepar...

journal_title：BMC nephrology

authors： Jesus-Silva JA,Lamplugh A,Dhada S,Burton JO,Bhandari S

更新日期：2020-06-03 00:00:00

abstract：BACKGROUND:Lupus nephritis (LN) is a severe consequence of systemic lupus erythematosus (SLE) that affects approximately 40% of patients. Pathogenic immune complexes that are characteristic of LN deposit in the kidney and activate immune mediated pathways including the complement system. Complete remission rates in LN ...

journal_title：BMC nephrology

authors： Wright RD,Bannerman F,Beresford MW,Oni L

更新日期：2020-06-30 00:00:00

abstract：BACKGROUND:Dose selection is an important step in pharmacokinetic (PK) studies of hemodialysis patients. We propose a simulation-based dose-selection method for PK studies of hemodialysis patients using a subpharmacological dose of oseltamivir as a model drug. METHODS:The concentrations of oseltamivir and its active m...

journal_title：BMC nephrology

authors： Kim DK,Lee JW,Shin KH,Kim S,Oh KH,Kim M,Yu KS,Lee JP,Lim CS,Kim YS,Joo KW

更新日期：2014-03-17 00:00:00

abstract：BACKGROUND:Self-management education needs have not been assessed in patients with complex co-morbid conditions such as diabetes and chronic kidney disease (CKD). The objectives of this study were to 1) determine the self-management education needs for patients with co-morbid diabetes and CKD and 2) co-develop an educa...

journal_title：BMC nephrology

authors： Zimbudzi E,Lo C,Kerr PG,Zoungas S

更新日期：2019-04-02 00:00:00

abstract：BACKGROUND:Proteinuria after kidney transplantation portends a worse graft survival. However the magnitude of proteinuria related to patient and graft survival and its correlation with donor and recipient characteristics are poorly explored. METHODS:This study investigated the impact of post transplant proteinuria in ...

journal_title：BMC nephrology

authors： Diena D,Messina M,De Biase C,Fop F,Scardino E,Rossetti MM,Barreca A,Verri A,Biancone L

更新日期：2019-12-02 00:00:00

abstract：INTRODUCTION:Urinary biomarkers of kidney injury are presumed to reflect renal tubular damage. However, their concentrations may be influenced by other factors, such as hematuria or pyuria. We sought to examine what non-injury related urinalysis factors are associated with urinary biomarker levels. METHODS:We examined...

journal_title：BMC nephrology

authors： Nadkarni GN,Coca SG,Meisner A,Patel S,Kerr KF,Patel UD,Koyner JL,Garg AX,Philbrook HT,Edelstein CL,Shlipak M,El-Khoury J,Parikh CR,TRIBE-AKI Consortium Investigators.

更新日期：2017-07-06 00:00:00

abstract：BACKGROUND:Non-tunneled (temporary) hemodialysis catheters (NTHCs) are the least-optimal initial vascular access for incident maintenance hemodialysis patients yet little is known about factors associated with NTHC use in this context. We sought to determine factors associated with NTHC use and examine regional and fac...

journal_title：BMC nephrology

authors： Clark EG,Akbari A,Hiebert B,Hiremath S,Komenda P,Lok CE,Moist LM,Schachter ME,Tangri N,Sood MM

更新日期：2016-02-27 00:00:00

abstract：BACKGROUND:There is a marked paucity of data concerning AKI in Sub-Saharan Africa, where there is a substantial burden of trauma and HIV. METHODS:Prospective data was collected on all patients admitted to a multi-disciplinary ICU in South Africa during 2017. Development of AKI (before or during ICU admission) was reco...

journal_title：BMC nephrology

authors： Aylward RE,van der Merwe E,Pazi S,van Niekerk M,Ensor J,Baker D,Freercks RJ

更新日期：2019-12-10 00:00:00

abstract：BACKGROUND:Data on radial access (RA) as an independent risk factor for acute kidney injury (AKI) in myocardial infarction (MI) patients are conflicting. Our aim was to assess how RA influences the incidence of AKI in MI patients undergoing percutaneous coronary intervention (PCI). METHODS:Data from 3842 MI patients u...

journal_title：BMC nephrology

authors： Kanic V,Kompara G,Šuran D,Tapajner A,Naji FH,Sinkovic A

更新日期：2019-01-30 00:00:00

abstract：BACKGROUND:This study aimed to compare clinical features and health-related quality of life (HRQoL) in the Chinese chronic kidney disease (CKD) 3 population and determined the necessity of the subdivision of CKD3 in Chinese patients with CKD. METHODS:Participants with stage 3 CKD (18-74 years of age) were recruited at...

journal_title：BMC nephrology

authors： Peng Z,Wang J,Yuan Q,Xiao X,Xu H,Xie Y,Wang W,Huang L,Zhong Y,Ao X,Zhang L,Zhao M,Tao L,Zhou Q,C-STRIDE study group.

更新日期：2017-10-13 00:00:00

abstract：BACKGROUND:Estimates of the incidence of glomerulonephritis (GN) and end-stage renal disease (ESRD) in an Iraqi population are compared with the United States (US) and Jordan. METHODS:The study set consist of renal biopsies performed in 2012 and 2013 in the Kurdish provinces of Northern Iraq. The age specific and age ...

journal_title：BMC nephrology

authors： Ali AA,Sharif DA,Almukhtar SE,Abd KH,Saleem ZSM,Hughson MD

更新日期：2018-10-11 00:00:00

abstract：BACKGROUND:The Reducing Disparities in Access to kidNey Transplantation Community Study (RaDIANT) was an End-Stage Renal Disease (ESRD) Network 6-developed, dialysis facility-level randomized trial testing the effectiveness of a 1-year multicomponent education and quality improvement intervention in increasing referral...

journal_title：BMC nephrology

authors： Hamoda RE,Gander JC,McPherson LJ,Arriola KJ,Cobb L,Pastan SO,Plantinga L,Browne T,Hartmann E,Mulloy L,Zayas C,Krisher J,Patzer RE

更新日期：2018-01-15 00:00:00

abstract：BACKGROUND:To date, limited research has been dedicated to exploring the experience of decision-making for chronic kidney disease (CKD) patients who have initiated dialysis and have to make decisions in the context of managing multiple illnesses. Evidence about the experience of decision-making for minority or disadvan...

journal_title：BMC nephrology

authors： Muscat DM,Kanagaratnam R,Shepherd HL,Sud K,McCaffery K,Webster A

更新日期：2018-11-27 00:00:00

abstract：BACKGROUND:Treatment of idiopathic membranous nephropathy with nephrotic syndrome is still controversial. There is currently little known about the clinical use of renal biomarkers which may explain contradictory results obtained from clinical trials. In order to assess whether IgG-uria can predict the outcome in membr...

journal_title：BMC nephrology

authors： Bazzi C,Rizza V,Casellato D,Tofik R,Berg AL,Gallieni M,D'Amico G,Bakoush O

更新日期：2014-05-08 00:00:00

abstract：BACKGROUND:Immunoglobulin light chains are classified as middle molecule uremic toxins able to interact with B lymphocyte membranes leading to the activation of transmembrane signaling. The ensuing impairment of neutrophil function can contribute to the chronic inflammation state of uremic patients, and the increased r...

journal_title：BMC nephrology

authors： Donati G,Moretti MI,Baraldi O,Spazzoli A,Capelli I,Comai G,Marchetti A,Sarma M,Mancini R,La Manna G

更新日期：2016-11-25 00:00:00

abstract：BACKGROUND:Rehabilitation effects of exercise training on adults with chronic kidney disease (CKD) have been generally recognised; however, the effects of exercise training on proteinuria have been underexplored. Our aim was to explore the effects of exercise training on proteinuria in adult CKD patients without renal ...

journal_title：BMC nephrology

authors： Yang L,Wu X,Wang Y,Wang C,Hu R,Wu Y

更新日期：2020-05-11 00:00:00

abstract：BACKGROUND:There is a high prevalence of cognitive impairment in dialysis patients. The prevalence of cognitive impairment after kidney transplantation is unknown. METHODS:Study Design: Cross-sectional study. SETTING AND PARTICIPANTS:Single center study of prevalent kidney transplant recipients from a transplant clin...

journal_title：BMC nephrology

authors： Gupta A,Mahnken JD,Johnson DK,Thomas TS,Subramaniam D,Polshak T,Gani I,John Chen G,Burns JM,Sarnak MJ

更新日期：2017-05-12 00:00:00

abstract：BACKGROUND:Patients undergoing haemodialysis (HD) are at higher risk of developing worse outcomes if they contract COVID-19. In our renal service we reduced HD frequency from thrice to twice-weekly in selected patients with the primary aim of reducing COVID 19 exposure and transmission between HD patients. METHODS:Dia...

journal_title：BMC nephrology

authors： Lodge MDS,Abeygunaratne T,Alderson H,Ali I,Brown N,Chrysochou C,Donne R,Erekosima I,Evans P,Flanagan E,Gray S,Green D,Hegarty J,Hyde A,Kalra PA,Lamerton E,Lewis D,Middleton R,New D,Nipah R,O'Donoghue D,O'Riordan

更新日期：2020-12-07 00:00:00

abstract：BACKGROUND:This study describes chronic kidney disease of uncertain aetiology (CKDu), which cannot be attributed to diabetes, hypertension or other known aetiologies, that has emerged in the North Central region of Sri Lanka. METHODS:A cross-sectional study was conducted, to determine the prevalence of and risk factor...

journal_title：BMC nephrology

authors： Jayatilake N,Mendis S,Maheepala P,Mehta FR,CKDu National Research Project Team.

更新日期：2013-08-27 00:00:00

abstract：BACKGROUND:Acute kidney injury (AKI) is common in hospitalized human immunodeficiency virus (HIV)-infected patients and is associated with hospital mortality. We aimed to evaluate the impact of AKI on long-term mortality of hospitalized HIV-infected patients. METHODS:Retrospective analysis of a cohort of 433 hospitali...

journal_title：BMC nephrology

authors： Lopes JA,Melo MJ,Raimundo M,Fragoso A,Antunes F

更新日期：2013-02-11 00:00:00

abstract：BACKGROUND:The KDIGO Clinical Practice Guidelines for Glomerulonephritis recommended tacrolimus as an alternative regimen for the initial therapy for Idiopathic membranous nephropathy (IMN), however, large observational studies evaluating tacrolimus treatment in IMN remains rare. METHODS:A total of 408 consecutive IMN...

journal_title：BMC nephrology

authors： Qin HZ,Liu L,Liang SS,Shi JS,Zheng CX,Hou Q,Lu YH,Le WB

更新日期：2017-01-05 00:00:00

abstract：BACKGROUND:A positive pregnancy test in acute or chronically ill patients has implications for the use of potentially mutagenic or teratogenic products in urgent medical therapies such as the use of chemotherapies or therapies with immunosuppressants, for anesthesia, and for time-sensitive indications like urgent surge...

journal_title：BMC nephrology

authors： Haninger-Vacariu N,Herkner H,Lorenz M,Säemann M,Vychytil A,Jansen M,Marculescu R,Kramar R,Sunder-Plassmann G,Schmidt A

更新日期：2020-02-28 00:00:00