Safely reducing haemodialysis frequency during the COVID-19 pandemic.

abstract：BACKGROUND:Major Depressive Disorder (MDD) can lead to adverse cardiovascular outcomes in patients with chronic kidney disease (CKD). Although one of the proposed mechanisms is heightened platelet activation, effects of MDD and its treatment with a selective serotonin reuptake inhibitor (SSRI) on platelet function in p...

journal_title：BMC nephrology

authors： Jain N,Wan F,Kothari M,Adelodun A,Ware J,Sarode R,Hedayati SS

更新日期：2019-10-29 00:00:00

abstract：BACKGROUND:Approximately 4-6% of incident end stage renal disease (ESRD) patients in the U.S. recover enough kidney function to discontinue dialysis but there is considerable geographic variation. We undertook this study to investigate whether state-level variations in renal recovery among incident ESRD patients correl...

journal_title：BMC nephrology

authors： Chen Z,Lee BJ,McCulloch CE,Burrows NR,Heung M,Hsu RK,Pavkov ME,Powe NR,Saran R,Shahinian V,Hsu CY,Centers for Disease Control and Prevention Chronic Kidney Disease Surveillance Team.

更新日期：2019-09-02 00:00:00

abstract：BACKGROUND:The patterns, performance characteristics, and yield of diagnostic tests ordered for the evaluation of acute kidney injury (AKI) have not been rigorously evaluated. METHODS:We characterized the frequency of AKI diagnostic testing for urine, blood, radiology, and pathology tests in all adult inpatients who w...

journal_title：BMC nephrology

authors： Leaf DE,Srivastava A,Zeng X,McMahon GM,Croy HE,Mendu ML,Kachalia A,Waikar SS

更新日期：2016-01-15 00:00:00

abstract：BACKGROUND:Complement activation plays a substantial role in the pathogenesis of primary membranous nephropathy (pMN). C5b-9, C3c, MBL, and factor B have been documented in the subepithelial immune deposits. However, the changing of complement activation products in circulation and urine is not clear. METHODS:We measu...

journal_title：BMC nephrology

authors： Zhang MF,Huang J,Zhang YM,Qu Z,Wang X,Wang F,Meng LQ,Cheng XY,Cui Z,Liu G,Zhao MH

更新日期：2019-08-09 00:00:00

abstract：BACKGROUND:HS219 (40 mg chitosan-loaded chewing gum) is designed to bind salivary phosphorus as an add-on to available phosphorus binders. We performed a randomized, placebo-controlled, double-blind study to evaluate the efficacy and safety of HS219 in hemodialysis (HD) patients with hyperphosphatemia as an add-on to p...

journal_title：BMC nephrology

authors： Akizawa T,Tsuruta Y,Okada Y,Miyauchi Y,Suda A,Kasahara H,Sasaki N,Maeda Y,Suzuki T,Matsui N,Niwayama J,Suzuki T,Hara H,Asano Y,Komemushi S,Fukagawa M

更新日期：2014-06-25 00:00:00

abstract：BACKGROUND:Single nucleotide polymorphisms (SNPs) are the most common forms of sequence variations in the human genome. They contribute to the human phenotypic spectrum and are associated with variations in response to pathogens, drugs and vaccines. Recently, SNPs in three human genes involved in kidney development (RE...

journal_title：BMC nephrology

authors： Raghavendra A,Siji A,Sridhar TS,Phadke K,Vasudevan A

更新日期：2011-10-28 00:00:00

abstract：BACKGROUND:The use of metformin in patients with type 2 diabetes mellitus has been associated with lactic acidosis. However, the information available in patients with moderate-severe chronic kidney disease is scarce. METHODS:The ALIMAR-C2 study is a case-control study to assess the association between metformin and l...

journal_title：BMC nephrology

authors： Pedrós C,Ávila M,Gómez-Lumbreras A,Manríquez M,Morros R,ALIMAR-C2 Study Group.

更新日期：2019-05-30 00:00:00

abstract：BACKGROUND:Patients with end-stage renal disease (ESRD) exhibit a premature aging phenotype of immune system, which is recently concerned as a significant factor for increased risk of various morbidities. Nevertheless, there are few dates explicating the relevancy of T cell senescence to mortality. In this study, we pr...

journal_title：BMC nephrology

authors： Xiang F,Chen R,Cao X,Shen B,Chen X,Ding X,Zou J

更新日期：2020-07-13 00:00:00

abstract：BACKGROUND:Urinary Ca2+ excretion increases with dietary NaCl. NaCl-induced calciuria may be associated with hypertension, urinary stone formation and osteoporosis, but its mechanism and long-term effects are not fully understood. This study examined alterations in the expressions of renal Ca2+ transporters, channels a...

journal_title：BMC nephrology

authors： Yatabe MS,Yatabe J,Takano K,Murakami Y,Sakuta R,Abe S,Sanada H,Kimura J,Watanabe T

更新日期：2012-12-02 00:00:00

abstract：BACKGROUND:Knowing how chronic kidney disease (CKD) patients talk about their encounters with providers (i.e., their discourse) can inform the important clinical goal of engaging patients in their chronic disease self-management. The aim of this study was to analyze patient discourse on ongoing CKD monitoring encounter...

journal_title：BMC nephrology

authors： Vandenberg AE,Echt KV,Johnson TM 2nd,Bowling CB

更新日期：2018-07-19 00:00:00

abstract：BACKGROUND:Family members of patients with end stage renal disease were reported to have an increased prevalence of chronic kidney disease (CKD). However, studies differentiated genetic and non-genetic family members are limited. We sought to investigate the prevalence of CKD among fist-degree relatives and spouses of ...

journal_title：BMC nephrology

authors： Kong X,Liu L,Zuo L,Yuan P,Li Z,Li W,Cai M,Chen X,Jiang A,Long G,Xu J,Lin H,Wang S,Huang W,Wang Y,Guo Y,Cao P,Wu H,Jia Q,Zhang L,Wang M,Wang H

更新日期：2013-01-18 00:00:00

abstract：BACKGROUND:Reproductive function in women with end stage renal disease generally improves after kidney transplant. However, pregnancy remains challenging due to the risk of adverse clinical outcomes. METHODS:We searched PubMed/MEDLINE, Elsevier EMBASE, Scopus, BIOSIS Previews, ISI Science Citation Index Expanded, and ...

journal_title：BMC nephrology

authors： Shah S,Venkatesan RL,Gupta A,Sanghavi MK,Welge J,Johansen R,Kean EB,Kaur T,Gupta A,Grant TJ,Verma P

更新日期：2019-01-23 00:00:00

abstract：BACKGROUND:In a recent study we demonstrated that low birth weight (LBW) was associated with increased risk of progressive IgA nephropathy (IgAN). In the present study we investigate whether this could be explained by differences in glomerular morphological parameters. METHODS:The Medical Birth Registry of Norway has ...

journal_title：BMC nephrology

authors： Ruggajo P,Leh S,Svarstad E,Marti HP,Vikse BE

更新日期：2018-10-22 00:00:00

abstract：BACKGROUND:Adult patients with minimal change nephrotic syndrome (MCNS) are often associated with acute kidney injury (AKI). To assess the mechanisms of AKI, we examined whether tubular cell injuries unique to MCNS patients exist. METHODS:We performed a retrospective analysis of clinical data and tubular cell changes ...

journal_title：BMC nephrology

authors： Fujigaki Y,Tamura Y,Nagura M,Arai S,Ota T,Shibata S,Kondo F,Yamaguchi Y,Uchida S

更新日期：2017-11-28 00:00:00

abstract：BACKGROUND:Glucocorticoids (GCs) are frequently used to treat glomerular diseases but are associated with multiple adverse effects including hypothalamic-pituitary-adrenal axis inhibition that can lead to adrenal insufficiency (AI) on withdrawal. There is no agreed GC tapering strategy to minimise this risk. METHODS:T...

journal_title：BMC nephrology

authors： Karangizi AHK,Al-Shaghana M,Logan S,Criseno S,Webster R,Boelaert K,Hewins P,Harper L

更新日期：2019-05-06 00:00:00

abstract：BACKGROUND:Dose selection is an important step in pharmacokinetic (PK) studies of hemodialysis patients. We propose a simulation-based dose-selection method for PK studies of hemodialysis patients using a subpharmacological dose of oseltamivir as a model drug. METHODS:The concentrations of oseltamivir and its active m...

journal_title：BMC nephrology

authors： Kim DK,Lee JW,Shin KH,Kim S,Oh KH,Kim M,Yu KS,Lee JP,Lim CS,Kim YS,Joo KW

更新日期：2014-03-17 00:00:00

abstract：BACKGROUND:Until now, no long-term studies relating serum albumin level to mortality rate in prevalent haemodialysis (HD) patients have been conducted. We aimed to examine the association between serum albumin level and mortality over a 5-year period. METHODS:This study included 781 patients who received maintenance H...

journal_title：BMC nephrology

authors： Chen JB,Cheng BC,Yang CH,Hua MS

更新日期：2016-08-20 00:00:00

abstract：BACKGROUND:Patients with advanced chronic kidney disease (CKD) exhibit higher prevalence of coronary artery calcification (CaC) than general population. CaC has been proposed as a risk factor for mortality in end-stage CKD, but most studies in the field are based on short-term follow-up. METHODS:We conducted a cohort,...

journal_title：BMC nephrology

authors： Cano-Megías M,Guisado-Vasco P,Bouarich H,de Arriba-de la Fuente G,de Sequera-Ortiz P,Álvarez-Sanz C,Rodríguez-Puyol D

更新日期：2019-05-28 00:00:00

abstract：BACKGROUND:S100A12 protein is an endogenous receptor ligand for advanced glycation end products. In this study, the plasma S100A12 level was assessed as an independent predictor of mortality, and its utility in clinical settings was examined. METHODS:In a previous cross-sectional study, plasma S100A12 levels were meas...

journal_title：BMC nephrology

authors： Shiotsu Y,Mori Y,Nishimura M,Hatta T,Imada N,Maki N,Iida K,Iwamoto N,Matsuoka E,Tamagaki K,Kosaki A

更新日期：2013-01-16 00:00:00

abstract：BACKGROUND:Nephrotic syndrome (NS) is pathological condition characterized by heavy proteinuria. Our study investigates hypothesis that change in cell proliferation of proximal tubules influences primary cilia structure and function and promotes cystogenesis in congenital nephrotic syndrome of the Finnish type (CNF) an...

journal_title：BMC nephrology

authors： Saraga M,Vukojević K,Krželj V,Puretić Z,Bočina I,Durdov MG,Weber S,Dworniczak B,Ljubanović DG,Saraga-Babić M

更新日期：2014-01-08 00:00:00

abstract：BACKGROUND:The product of the concentrations of urinary tissue inhibitor of metalloproteinases-2 and insulin-like growth factor binding protein-7 (urinary [TIMP-2] × [IGFBP-7]) has been suggested as biomarker for early detection of acute kidney injury (AKI) in various clinical settings. However, the performance of urin...

journal_title：BMC nephrology

authors： Schiefer J,Lichtenegger P,Berlakovich GA,Plöchl W,Krenn CG,Baron DM,Baron-Stefaniak J,Faybik P

更新日期：2019-07-17 00:00:00

abstract：BACKGROUND:In patients with autosomal dominant polycystic kidney disease (ADPKD), malnutrition may develop as renal function declines and the abdominal organs become enlarged. We investigated the relationship of intra-abdominal mass with nutritional status. METHODS:This cross-sectional study was performed at a tertiar...

journal_title：BMC nephrology

authors： Ryu H,Kim H,Park HC,Kim H,Cho EJ,Lee KB,Chung W,Oh KH,Cho JY,Hwang YH,Ahn C

更新日期：2017-01-14 00:00:00

abstract：:In a recent study published by the National Project Team on chronic kidney diseases of unknown origin in Sri Lanka, identified cadmium as a major risk factor but strong conclusions were not made as the identified environmental toxins were within the permissible levels.Sri Lankan food consumption pattern is different s...

journal_title：BMC nephrology

authors： Jayalal TB

更新日期：2015-12-23 00:00:00

abstract：BACKGROUND:There is limited evidence on the relationship between social support and renal outcomes in African Americans. We sought to determine the association of social support with prevalent chronic kidney disease (CKD) and kidney function decline in an African American cohort. We also examined whether age modifies t...

journal_title：BMC nephrology

authors： Hall RK,Davenport CA,Sims M,Colón-Emeric C,Washington T,St Clair Russell J,Pendergast J,Bhavsar N,Scialla J,Tyson CC,Wang W,Min YI,Young B,Boulware LE,Diamantidis CJ

更新日期：2019-07-15 00:00:00

abstract：BACKGROUND:A previous cohort study indicated a significant association of lower baseline level of physical activity in hemodialysis patients with elevated risks of mortality. However, there have been no reports regarding the association between changes in physical activity over time and mortality in hemodialysis patien...

journal_title：BMC nephrology

authors： Shimoda T,Matsuzawa R,Yoneki K,Harada M,Watanabe T,Matsumoto M,Yoshida A,Takeuchi Y,Matsunaga A

更新日期：2017-05-08 00:00:00

abstract：BACKGROUND:About 1% of patients admitted to the Emergency Department (ED) have hypernatremia, a condition associated with a mortality rate of 20 to 60%. Management recommendations originate from intensive care unit studies, in which patients and medical diseases differ from those in ED. METHODS:We retrospectively stud...

journal_title：BMC nephrology

authors： Bataille S,Baralla C,Torro D,Buffat C,Berland Y,Alazia M,Loundou A,Michelet P,Vacher-Coponat H

更新日期：2014-02-21 00:00:00

abstract：BACKGROUND:Chronic active antibody-mediated rejection is a major etiology of graft loss in renal transplant recipients. However, there is no consensus on the optimal treatment strategies. METHODS:Computerized records from Taichung Veterans General Hospital were collected to identify renal transplant biopsies performed...

journal_title：BMC nephrology

authors： Chiu HF,Wen MC,Wu MJ,Chen CH,Yu TM,Chuang YW,Huang ST,Tsai SF,Lo YC,Ho HC,Shu KH

更新日期：2020-01-06 00:00:00

abstract：BACKGROUND:Tissue derived biomarkers may offer utility as indicators of accumulated damage. Reduced thickness of retinal neuronal tissue and the vascular choroid have previously been associated with vascular damage and diabetes. We evaluated associations between retinal thickness, retinal microvascular and choroidal me...

journal_title：BMC nephrology

authors： Paterson EN,Ravindran ML,Griffiths K,Le Velly CA,Cardwell CC,McCarter RV,Nicol P,Chhablani JK,Rasheed MA,Vupparaboina KK,MacGillivray TJ,Harbinson M,Maxwell AP,Hogg RE,McKay GJ

更新日期：2020-01-31 00:00:00

abstract：BACKGROUND:Acute kidney injury (AKI) is common in hospitalized human immunodeficiency virus (HIV)-infected patients and is associated with hospital mortality. We aimed to evaluate the impact of AKI on long-term mortality of hospitalized HIV-infected patients. METHODS:Retrospective analysis of a cohort of 433 hospitali...

journal_title：BMC nephrology

authors： Lopes JA,Melo MJ,Raimundo M,Fragoso A,Antunes F

更新日期：2013-02-11 00:00:00

abstract：BACKGROUND:Cardiovascular morbidity and mortality are highly prevalent in patients with end-stage renal disease, and osteoprotegerin (OPG) may be an important link between bone loss and vascular calcification. This study was conducted to evaluate the relationship between central arterial stiffness and serum OPG levels ...

journal_title：BMC nephrology

authors： Hou JS,Lin YL,Wang CH,Lai YH,Kuo CH,Subeq YM,Hsu BG

更新日期：2019-05-23 00:00:00