Dose selection method for pharmacokinetic study in hemodialysis patients using a subpharmacological dose: oseltamivir as a model drug.

abstract：BACKGROUND:Observational studies have demonstrated an association between nephrolithiasis and hypertension. The aim of this meta-analysis was to summarize all available evidence. METHODS:PubMed, EMBASE, the Cochrane Central Register of Controlled Trials databases, and the reference lists of relevant articles were sear...

journal_title：BMC nephrology

authors： Shang W,Li Y,Ren Y,Yang Y,Li H,Dong J

更新日期：2017-11-29 00:00:00

abstract：BACKGROUND:Fibroblast growth factor 23 (FGF23) is a phosphaturic hormone that is secreted from bone and serum level increases as renal function declines. Higher levels of FGF23 are associated with increased mortality in hemodialysis-patients and in patients with chronic kidney disease (CKD) stage 2-4. The use of active...

journal_title：BMC nephrology

authors： Bleskestad IH,Bergrem H,Hartmann A,Godang K,Gøransson LG

更新日期：2012-06-28 00:00:00

abstract：BACKGROUND:The currently available data with respect to the association between vitamin D receptor (VDR) gene polymorphism and risk to urolithiasis are inconclusive and inconsistent. Hence, an exhaustive meta-analysis can solve the discrepancies and provide a hint for upcoming investigations. Herein, a meta-analysis wa...

journal_title：BMC nephrology

authors： Imani D,Razi B,Khosrojerdi A,Lorian K,Motallebnezhad M,Rezaei R,Aslani S

更新日期：2020-07-10 00:00:00

abstract：BACKGROUND:Severe renal manifestation of systemic lupus erythematosus (SLE) is not uncommon and is associated with an indeterminate prognosis. Complete remission can be obtained, however, at least in the young when chronic lesions are absent and adequate anti-inflammatory therapy is immediately initiated. CASE PRESENT...

journal_title：BMC nephrology

authors： Ross S,Benz K,Sauerstein K,Amann K,Dötsch J,Dittrich K

更新日期：2012-08-06 00:00:00

abstract：BACKGROUND:Neutrophil gelatinase associated lipocalin (NGAL) is a highly predictive biomarker of acute kidney injury. To understand the role of NGAL in renal injury during sepsis, we investigated the temporal changes and biological sources of NGAL in a rat model of acute kidney injury, and explored the relationship bet...

journal_title：BMC nephrology

authors： Han M,Li Y,Liu M,Li Y,Cong B

更新日期：2012-06-27 00:00:00

abstract：BACKGROUND:Proteinuria after kidney transplantation portends a worse graft survival. However the magnitude of proteinuria related to patient and graft survival and its correlation with donor and recipient characteristics are poorly explored. METHODS:This study investigated the impact of post transplant proteinuria in ...

journal_title：BMC nephrology

authors： Diena D,Messina M,De Biase C,Fop F,Scardino E,Rossetti MM,Barreca A,Verri A,Biancone L

更新日期：2019-12-02 00:00:00

abstract：BACKGROUND:This study will assess measures of vascular health and inflammation in Aboriginal Australian adults with chronic kidney disease (CKD), and determine if intensive periodontal intervention improves cardiovascular health, progression of renal disease and periodontal health over a 24-month follow-up. METHODS:Th...

journal_title：BMC nephrology

authors： Jamieson L,Skilton M,Maple-Brown L,Kapellas K,Askie L,Hughes J,Arrow P,Cherian S,Fernandes D,Pawar B,Brown A,Boffa J,Hoy W,Harris D,Mueller N,Cass A

更新日期：2015-10-31 00:00:00

abstract：BACKGROUND:The clinical outcomes of ST-segment elevation myocardial infarction (STEMI) are poor in patients with renal insufficiency. This study investigated changes in the likelihood that patients received optimal medical care throughout the entire process of myocardial infarction management, on the basis of their glo...

journal_title：BMC nephrology

authors： Choi JS,Kim CS,Bae EH,Ma SK,Jeong MH,Kim YJ,Cho MC,Kim CJ,Kim SW

更新日期：2012-09-11 00:00:00

abstract：BACKGROUND:Previous studies have linked smaller kidney dimensions to increased blood pressure. However, patients with Balkan Endemic Nephropathy (BEN), whose kidneys shrink during the course of the disease, do not manifest increased blood pressure. The authors evaluated the relationship between kidney cortex width, kid...

journal_title：BMC nephrology

authors： Dimitrov PS,Simeonov VA,Tsolova SD,Bonev AG,Georgieva RB,Karmaus WJ

更新日期：2006-08-23 00:00:00

abstract：BACKGROUND:Echocardiographic characteristics across the spectrum of chronic kidney disease (CKD) have not been well described. We assessed the echocardiographic characteristics of patients with preserved renal function and mild or moderate CKD referred for echocardiography and determined whether echocardiographic param...

journal_title：BMC nephrology

authors： Mavrakanas TA,Khattak A,Singh K,Charytan DM

更新日期：2018-07-11 00:00:00

abstract：BACKGROUND:Data on radial access (RA) as an independent risk factor for acute kidney injury (AKI) in myocardial infarction (MI) patients are conflicting. Our aim was to assess how RA influences the incidence of AKI in MI patients undergoing percutaneous coronary intervention (PCI). METHODS:Data from 3842 MI patients u...

journal_title：BMC nephrology

authors： Kanic V,Kompara G,Šuran D,Tapajner A,Naji FH,Sinkovic A

更新日期：2019-01-30 00:00:00

abstract：BACKGROUND:Chronic kidney disease (CKD) is a common comorbid condition in coronary heart disease (CHD). CKD predisposes the patient to acute kidney injury (AKI) during hospitalization. Data on awareness of kidney dysfunction among CHD patients and their treating physicians are lacking. In the current cross-sectional an...

journal_title：BMC nephrology

authors： Wagner M,Wanner C,Schich M,Kotseva K,Wood D,Hartmann K,Fette G,Rücker V,Oezkur M,Störk S,Heuschmann PU

更新日期：2017-10-25 00:00:00

abstract：BACKGROUND:Metabolic acidosis leads to chronic kidney disease (CKD) progression. The guidelines recommend a lower limit of serum bicarbonate level, but no upper limit. For serum bicarbonate level to be clinically useful as a therapeutic target marker, it is necessary to investigate the target serum bicarbonate level wi...

journal_title：BMC nephrology

authors： Kanda E,Ai M,Yoshida M,Kuriyama R,Shiigai T

更新日期：2013-01-09 00:00:00

abstract：BACKGROUND:The use of metformin in patients with type 2 diabetes mellitus has been associated with lactic acidosis. However, the information available in patients with moderate-severe chronic kidney disease is scarce. METHODS:The ALIMAR-C2 study is a case-control study to assess the association between metformin and l...

journal_title：BMC nephrology

authors： Pedrós C,Ávila M,Gómez-Lumbreras A,Manríquez M,Morros R,ALIMAR-C2 Study Group.

更新日期：2019-05-30 00:00:00

abstract：BACKGROUND:Patients with end-stage renal disease (ESRD) under hemodialysis (HD) are at greater risks of infectious spondylitis (IS), but there is no reliable predictor that facilitate early detection of this relatively rare and insidious disease. METHODS:A retrospective review of the medical records from patients with...

journal_title：BMC nephrology

authors： Lu KL,Huang WH,Lu YA,Lin CY,Wu HH,Hsu CW,Weng CH,Wu CY,Wu IW,Wu MY,Yen TH,Yang HY

更新日期：2019-08-16 00:00:00

abstract：BACKGROUND:Interleukin 17 is a proinflammatory cytokine involved in immune response after allograft transplantation. IL-17 family of proinflammatory cytokines includes IL-17A and IL-17F. Previous studies have demonstrated that the rs2275913 IL17A and the rs11465553 IL17F gene polymorphism are associated with kidney all...

journal_title：BMC nephrology

authors： Domanski L,Kłoda K,Patrzyk M,Wisniewska M,Safranow K,Sienko J,Sulikowski T,Staniszewska M,Pawlik A

更新日期：2019-04-08 00:00:00

abstract：BACKGROUND:Dialysis has long been a critical issue in the field of nephrology, though the burden this lifesaving technology places on society can be immense. Effectively increasing the health literacy of hemodialysis patients can be beneficial for their health outcomes and self-care abilities. Thus, the aims of this st...

journal_title：BMC nephrology

authors： Shih CL,Chang TH,Jensen DA,Chiu CH

更新日期：2016-05-31 00:00:00

abstract：BACKGROUND:Reproductive function in women with end stage renal disease generally improves after kidney transplant. However, pregnancy remains challenging due to the risk of adverse clinical outcomes. METHODS:We searched PubMed/MEDLINE, Elsevier EMBASE, Scopus, BIOSIS Previews, ISI Science Citation Index Expanded, and ...

journal_title：BMC nephrology

authors： Shah S,Venkatesan RL,Gupta A,Sanghavi MK,Welge J,Johansen R,Kean EB,Kaur T,Gupta A,Grant TJ,Verma P

更新日期：2019-01-23 00:00:00

abstract：BACKGROUND:There is a marked paucity of data concerning AKI in Sub-Saharan Africa, where there is a substantial burden of trauma and HIV. METHODS:Prospective data was collected on all patients admitted to a multi-disciplinary ICU in South Africa during 2017. Development of AKI (before or during ICU admission) was reco...

journal_title：BMC nephrology

authors： Aylward RE,van der Merwe E,Pazi S,van Niekerk M,Ensor J,Baker D,Freercks RJ

更新日期：2019-12-10 00:00:00

abstract：BACKGROUND:Diabetic nephropathy is a global common cause of chronic kidney disease and end-stage renal disease. A lot of research has been conducted in biomedical sciences, which has enhanced understanding of the pathophysiology of diabetic nephropathy and has expanded the potential available therapies. An increasing n...

journal_title：BMC nephrology

authors： De la Cruz-Cano E,Jiménez-González CDC,Morales-García V,Pineda-Pérez C,Tejas-Juárez JG,Rendón-Gandarilla FJ,Jiménez-Morales S,Díaz-Gandarilla JA

更新日期：2019-10-28 00:00:00

abstract：BACKGROUND:Although hemodialysis (HD) adequacy, single-pool Kt/Vurea (spKt/V), is inversely correlated with body size, each is known to affect patient survival in the same direction. Therefore, we sought to examine the relationship between HD adequacy and mortality according to body mass index (BMI) in HD patients and ...

journal_title：BMC nephrology

authors： Hong WP,Lee YJ

更新日期：2019-10-22 00:00:00

abstract：BACKGROUND:Neutrophil extracellular traps (NETs) are web-like DNA decorated with antimicrobial proteins, such as myeloperoxidase (MPO), which are extruded from activated neutrophils. Although NETs are essential in innate immunity, an excessive formation of NETs has adverse effects, e.g., induction of anti-neutrophil cy...

journal_title：BMC nephrology

authors： Shida H,Hashimoto N,Kusunoki Y,Hattanda F,Ogawa Y,Hayashi T,Nakazawa D,Masuda S,Tomaru U,Ishizu A

更新日期：2018-06-22 00:00:00

abstract：BACKGROUND:Indoleamine 2, 3-dioxygenase (IDO) is an immunomodulatory molecule that has been implicated in several biological processes. Although IDO has been linked with some renal diseases, its role in renal fibrosis is still unclear. Because IDO may be modulated by TGF-β1, a potent fibrogenic molecule, we hypothesize...

journal_title：BMC nephrology

authors： Matheus LHG,Simão GM,Amaral TA,Brito RBO,Malta CS,Matos YST,Santana AC,Rodrigues GGC,Albejante MC,Bach EE,Dalboni MA,Camacho CP,Dellê H

更新日期：2017-09-06 00:00:00

abstract：BACKGROUND:The extent to which smoking contributes to adverse outcomes among men and women of all ages undergoing dialysis is uncertain. The objective of this study was to determine the differential impact of smoking on risks of mortality and kidney transplantation by age and by sex at dialysis initiation. METHODS:We ...

journal_title：BMC nephrology

authors： Stack AG,Yermak D,Roche DG,Ferguson JP,Elsayed M,Mohammed W,Casserly LF,Walsh SR,Cronin CJ

更新日期：2016-07-26 00:00:00

abstract：BACKGROUND:Major Depressive Disorder (MDD) can lead to adverse cardiovascular outcomes in patients with chronic kidney disease (CKD). Although one of the proposed mechanisms is heightened platelet activation, effects of MDD and its treatment with a selective serotonin reuptake inhibitor (SSRI) on platelet function in p...

journal_title：BMC nephrology

authors： Jain N,Wan F,Kothari M,Adelodun A,Ware J,Sarode R,Hedayati SS

更新日期：2019-10-29 00:00:00

abstract：BACKGROUND:The objective of the study was to examine overall anemia management trends in non-dialysis patients with chronic kidney disease (CKD) from 2006 to 2015, and to evaluate the impact of Trial to Reduced Cardiovascular Events with Ananesp Therapy (TREAT)'s study results (October 2009) and the US Food and Drug Ad...

journal_title：BMC nephrology

authors： Park H,Liu X,Henry L,Harman J,Ross EA

更新日期：2018-11-09 00:00:00

abstract：BACKGROUND:The diagnosis of myeloma, a plasma dyscrasia, often results from the workup of unexplained renal disease. Persistent renal failure in myeloma is commonly caused by tubular nephropathy due to circulating immunoglobulins and free light chains. Myeloma cast nephropathy is characterized by crystalline precipitat...

journal_title：BMC nephrology

authors： Wu CK,Yang AH,Lai HC,Lin BS

更新日期：2017-05-25 00:00:00

abstract：BACKGROUND:In a previous study we showed that troponin I (TnI) > 0.42 ng/mL predicted the need of dialysis in a group of 29 septic patients admitted to the intensive care unit (ICU). We aimed to confirm such finding in a larger independent sample. METHODS:All septic patients admitted to an ICU from March 2016 to Febru...

journal_title：BMC nephrology

authors： de Almeida Thiengo D,Strogoff-de-Matos JP,Lugon JR,Graciano ML

更新日期：2018-11-20 00:00:00

abstract：BACKGROUND:Multiple factors influence timing of dialysis initiation. The impact of supply of nephrology workforce on timing and incidence of dialysis initiation is not well known. METHODS:We determined the number of pediatric and adult nephrologists in each state using data from the American Medical Association and Am...

journal_title：BMC nephrology

authors： Ku E,Johansen KL,Portale AA,Grimes B,Hsu CY

更新日期：2015-01-15 00:00:00

abstract：BACKGROUND:ANCA-associated vasculitis is a life-threatening, systemic autoimmune disease. There is an increased risk of organ infarction but in many cases this is asymptomatic. We described here the first reported case of PR3 vasculitis presenting with symptomatic bilateral renal wedge infarction. CASE PRESENTATION:A ...

journal_title：BMC nephrology

authors： Bottomley MJ,Gibson M,Alchi B

更新日期：2019-03-06 00:00:00