Protective effect of quinacrine against glycerol-induced acute kidney injury in rats.

abstract：BACKGROUND:Aluminium (Al) toxicity was frequent in the 1980s in patients ingesting Al containing phosphate binders (Alucaps) whilst having HD using water potentially contaminated with Al. The aim of this study was to determine the risk of Al toxicity in HD patients receiving Alucaps but never exposed to contaminated di...

journal_title：BMC nephrology

authors： Pepper R,Campbell N,Yaqoob MM,Roberts NB,Fan SL

更新日期：2011-10-12 00:00:00

abstract：BACKGROUND:Obstetric-related acute kidney injury (AKI) is thought to be a key contributor to the overall burden of AKI in low resource settings, causing significant and preventable morbidity and mortality. However, epidemiological data to corroborate these hypotheses is sparse. This prospective observational study aims...

journal_title：BMC nephrology

authors： Cooke WR,Hemmilä UK,Craik AL,Mandula CJ,Mvula P,Msusa A,Dreyer G,Evans R

更新日期：2018-02-02 00:00:00

abstract：BACKGROUND:Sclerostin is a paracrine acting factor, which is expressed in the osteocytes and articular chondrocytes. Sclerostin decreases the osteoblast-related bone formation through the inhibition of the Wnt/β-catenin pathway. Osteocytes also express the Calcium sensing receptor which is a target for cinacalcet. The ...

journal_title：BMC nephrology

authors： Kuczera P,Adamczak M,Więcek A

更新日期：2016-11-15 00:00:00

abstract：BACKGROUND:Glomerular filtration rate (GFR) is the best index of renal function, but age, gender and ethnicity can putatively affect its values. The aim of this study was to establish reference values for GFR in healthy Brazilian subjects while taking these factors into account. METHODS:In this cross-sectional study, ...

journal_title：BMC nephrology

authors： Soares AA,Prates AB,Weinert LS,Veronese FV,de Azevedo MJ,Silveiro SP

更新日期：2013-02-28 00:00:00

abstract：BACKGROUND:Knowing how chronic kidney disease (CKD) patients talk about their encounters with providers (i.e., their discourse) can inform the important clinical goal of engaging patients in their chronic disease self-management. The aim of this study was to analyze patient discourse on ongoing CKD monitoring encounter...

journal_title：BMC nephrology

authors： Vandenberg AE,Echt KV,Johnson TM 2nd,Bowling CB

更新日期：2018-07-19 00:00:00

abstract：BACKGROUND:Residing remotely from health care resources appears to impact quality of care delivery. It remains unclear if there are differences in vascular access based on distance of one's residence to dialysis centre at time of dialysis initiation, and whether region or duration of pre-dialysis care are important eff...

journal_title：BMC nephrology

authors： Miller LM,Vercaigne LM,Moist L,Lok CE,Tangri N,Komenda P,Rigatto C,Mojica J,Sood MM

更新日期：2014-02-27 00:00:00

abstract：BACKGROUND:There is a high prevalence of cognitive impairment in dialysis patients. The prevalence of cognitive impairment after kidney transplantation is unknown. METHODS:Study Design: Cross-sectional study. SETTING AND PARTICIPANTS:Single center study of prevalent kidney transplant recipients from a transplant clin...

journal_title：BMC nephrology

authors： Gupta A,Mahnken JD,Johnson DK,Thomas TS,Subramaniam D,Polshak T,Gani I,John Chen G,Burns JM,Sarnak MJ

更新日期：2017-05-12 00:00:00

abstract：BACKGROUND:Asians have among the highest prevalence of chronic kidney disease (CKD) or end-stage renal disease in the world. A risk score capable of identifying high risk individuals at the primary care level could allow targeted therapy to prevent future development of CKD. Risk scores for new CKD have been developed ...

journal_title：BMC nephrology

authors： Saranburut K,Vathesatogkit P,Thongmung N,Chittamma A,Vanavanan S,Tangstheanphan T,Sritara P,Kitiyakara C

更新日期：2017-07-17 00:00:00

abstract：BACKGROUND:Group A streptococcus (GAS) is an etiological agent for the immune mediated sequela post streptococcal glomerulonephritis (PSGN). In some populations PSGN is recognized as a risk factor for chronic kidney disease (CKD) and end-stage renal disease (ESRD). It was found that a significantly greater proportion o...

journal_title：BMC nephrology

authors： Karmarkar MG,Hule GP,Hase NK,Mehta PR,Walter SR,Sriprakash KS

更新日期：2013-05-06 00:00:00

abstract：BACKGROUND:Autosomal dominant polycystic kidney disease (ADPKD) is the leading inheritable cause of end-stage renal disease (ESRD); however, the natural course of disease progression is heterogeneous between patients. This study aimed to develop a natural history model of ADPKD that predicted progression rates and long...

journal_title：BMC nephrology

authors： McEwan P,Bennett Wilton H,Ong ACM,Ørskov B,Sandford R,Scolari F,Cabrera MV,Walz G,O'Reilly K,Robinson P

更新日期：2018-02-13 00:00:00

abstract：BACKGROUND:There is a perception that kidney transplant recipients transferred from pediatric centers to adult care have an increased risk of graft loss. It is not clear whether young adults transplanted in adult centers also suffer from high graft loss rates. METHODS:We examined death censored graft survival in 3 coh...

journal_title：BMC nephrology

authors： Kiberd JA,Acott P,Kiberd BA

更新日期：2011-10-07 00:00:00

abstract：BACKGROUND:Acute kidney injury (AKI) remains a frequent complication in children undergoing hematopoietic stem cell transplantation (HSCT) and an independent risk factor of the patient's survival and a prognostic factor of progression to chronic kidney disease (CKD). However, the causes of these complications are diver...

journal_title：BMC nephrology

authors： Hirano D,Kakegawa D,Miwa S,Umeda C,Takemasa Y,Tokunaga A,Kawakami Y,Ito A

更新日期：2020-08-27 00:00:00

abstract：BACKGROUND:Dementia is common in end-stage renal disease (ESRD) patients on hemodialysis (HD) and is associated with worse outcomes. This study aimed to investigate the risk of major adverse cardiac and cerebrovascular event (MACCE) in elderly patients with dementia initiating HD. METHODS:Using the database from the H...

journal_title：BMC nephrology

authors： Jung SM,Kim CT,Kang EW,Kim KH,Lee S,Oh HJ,Kim SJ,Kang DH,Choi KB,Ryu DR,Kim H

更新日期：2017-04-06 00:00:00

abstract：BACKGROUND:Frailty is independently associated with worse health-related quality of life (HRQOL) in chronic kidney disease (CKD). However, the relationship between frailty and symptom experience is not well described in people living with CKD. This study's aim was to evaluate the relationship between frailty and sympto...

journal_title：BMC nephrology

authors： Nixon AC,Wilkinson TJ,Young HML,Taal MW,Pendleton N,Mitra S,Brady ME,Dhaygude AP,Smith AC

更新日期：2020-09-23 00:00:00

abstract：BACKGROUND:Tolvaptan is a selective vasopressin receptor antagonist. Nitric Oxide (NO) promotes renal water and sodium excretion, but the effect is unknown in the nephron's principal cells. In a dose-response study, we measured the effect of tolvaptan on renal handling of water and sodium and systemic hemodynamics, dur...

journal_title：BMC nephrology

authors： Al Therwani S,Rosenbæk JB,Mose FH,Bech JN,Pedersen EB

更新日期：2017-03-13 00:00:00

abstract：BACKGROUND:Physical activity (PA) is exceptionally low amongst the haemodialysis (HD) population, and physical inactivity is a powerful predictor of mortality, making it a prime focus for intervention. Objective measurement of PA using accelerometers is increasing, but standard reporting guidelines essential to effecti...

journal_title：BMC nephrology

authors： Young HML,Orme MW,Song Y,Dungey M,Burton JO,Smith AC,Singh SJ

更新日期：2019-12-04 00:00:00

abstract：BACKGROUND:Chronic hepatitis B virus (HBV) infection and chronic kidney disease (CKD) have high prevalences in Taiwan and worldwide. However, the association of untreated chronic hepatitis B virus (HBV) infection with chronic kidney disease (CKD) remains unclear. METHODS:This cohort study used claims data in the Taiwa...

journal_title：BMC nephrology

authors： Chen YC,Su YC,Li CY,Hung SK

更新日期：2015-07-22 00:00:00

abstract：BACKGROUND:Vancomycin is the first-line antibiotic for methicillin-resistant Staphylococcus aureus and coagulase-negative strains. The risk of vancomycin-induced acute kidney injury increases with plasma vancomycin levels. Vancomycin-induced acute kidney injury is histologically characterized by acute interstitial neph...

journal_title：BMC nephrology

authors： Sawada A,Kawanishi K,Morikawa S,Nakano T,Kodama M,Mitobe M,Taneda S,Koike J,Ohara M,Nagashima Y,Nitta K,Mochizuki T

更新日期：2018-03-27 00:00:00

abstract：BACKGROUND:Anaemia is common in haemodialysis (HD) patients and associated with significant morbidity and mortality. Intravenous (IV) iron combined with erythropoiesis-stimulating agents (ESA) is the mainstay treatment of anaemia in these patients. The comparative efficacy and risk of adverse events with IV iron prepar...

journal_title：BMC nephrology

authors： Jesus-Silva JA,Lamplugh A,Dhada S,Burton JO,Bhandari S

更新日期：2020-06-03 00:00:00

abstract：INTRODUCTION:Urinary biomarkers of kidney injury are presumed to reflect renal tubular damage. However, their concentrations may be influenced by other factors, such as hematuria or pyuria. We sought to examine what non-injury related urinalysis factors are associated with urinary biomarker levels. METHODS:We examined...

journal_title：BMC nephrology

authors： Nadkarni GN,Coca SG,Meisner A,Patel S,Kerr KF,Patel UD,Koyner JL,Garg AX,Philbrook HT,Edelstein CL,Shlipak M,El-Khoury J,Parikh CR,TRIBE-AKI Consortium Investigators.

更新日期：2017-07-06 00:00:00

abstract：BACKGROUND:Haemodialysis is the most common form of renal replacement therapy in Nigeria. The high cost of haemodialysis has made optimal therapy of end-stage renal disease difficult in Nigeria. This paper is a review of data collected over two years of provision of dialysis services in a new tertiary hospital in South...

journal_title：BMC nephrology

authors： Ekrikpo UE,Udo AI,Ikpeme EE,Effa EE

更新日期：2011-10-02 00:00:00

abstract：BACKGROUND:Efficient and safe delivery of care to dialysis patients is essential. Concerns have been raised regarding the ability of accountable care organizations to adequately serve this high-risk population. Little is known about primary care involvement in the care of dialysis patients. This study sought to describ...

journal_title：BMC nephrology

authors： Thorsteinsdottir B,Ramar P,Hickson LJ,Reinalda MS,Albright RC,Tilburt JC,Williams AW,Takahashi PY,Jeffery MM,Shah ND

更新日期：2017-10-25 00:00:00

abstract：BACKGROUND:Canada's pandemic H1N1 influenza A (pH1N1) outbreak led to a high burden of critical illness. Our objective was to describe the incidence of AKI (acute kidney injury) in these patients and risk factors for AKI, renal replacement therapy (RRT), and mortality. METHODS:From a prospective cohort of critically i...

journal_title：BMC nephrology

authors： Bagshaw SM,Sood MM,Long J,Fowler RA,Adhikari NK,Canadian Critical Care Trials Group H1N1 Collaborative.

更新日期：2013-06-13 00:00:00

abstract：BACKGROUND:In patients with autosomal dominant polycystic kidney disease (ADPKD), malnutrition may develop as renal function declines and the abdominal organs become enlarged. We investigated the relationship of intra-abdominal mass with nutritional status. METHODS:This cross-sectional study was performed at a tertiar...

journal_title：BMC nephrology

authors： Ryu H,Kim H,Park HC,Kim H,Cho EJ,Lee KB,Chung W,Oh KH,Cho JY,Hwang YH,Ahn C

更新日期：2017-01-14 00:00:00

abstract：BACKGROUND:End-Stage Renal disease (ESRD) is associated with increased morbidity and mortality. We assessed the occurrence, time-trend and determinants of fatal outcomes of haemodialysis-treated ESRD patients over a 10-year period in a major referral hospital in Cameroon. METHODS:Medical records of ESRD patients who s...

journal_title：BMC nephrology

authors： Halle MP,Ashuntantang G,Kaze FF,Takongue C,Kengne AP

更新日期：2016-11-03 00:00:00

abstract：BACKGROUND:Until now, no long-term studies relating serum albumin level to mortality rate in prevalent haemodialysis (HD) patients have been conducted. We aimed to examine the association between serum albumin level and mortality over a 5-year period. METHODS:This study included 781 patients who received maintenance H...

journal_title：BMC nephrology

authors： Chen JB,Cheng BC,Yang CH,Hua MS

更新日期：2016-08-20 00:00:00

abstract：BACKGROUND:There is limited knowledge of Chronic Kidney Disease (CKD) among high risk populations, especially in the developing countries. We report our study of testing for CKD in at-risk subjects. METHODS:In a cross-sectional study, 527 people from primary and secondary health care areas in the city of Kinshasa were...

journal_title：BMC nephrology

authors： Sumaili EK,Cohen EP,Zinga CV,Krzesinski JM,Pakasa NM,Nseka NM

更新日期：2009-07-21 00:00:00

abstract：BACKGROUND:High water hardness associated with high water fluoride and the geographical distribution of Chronic Kidney Disease of unknown etiology (CKDu) in Sri Lanka are well correlated. We undertook this study to observe the effects of high water hardness with high fluoride on kidney and liver in rats and efficacy of...

journal_title：BMC nephrology

authors： Perera T,Ranasinghe S,Alles N,Waduge R

更新日期：2020-03-24 00:00:00

abstract：BACKGROUND:This study was aimed at determining the outcome and examining the association between comorbidities and mortality after intracerebral hemorrhage in chronic dialysis patients. METHODS:We used the Taiwan National Health Insurance Research Database and enrolled patients who underwent maintenance dialysis betwe...

journal_title：BMC nephrology

authors： Lin CY,Chien CC,Chen HA,Su FM,Wang JJ,Wang CC,Chu CC,Lin YJ

更新日期：2014-11-27 00:00:00

abstract：BACKGROUND:Recipients of living donor renal transplantation are typically considered to have a relatively lower immunological risk. This retrospective study aimed to compare the therapeutic efficacy and safety between rabbit antithymocyte globulin (rATG) or interleukin-2 receptor antagonist (IL2-RA) induction therapies...

journal_title：BMC nephrology

authors： Qiu J,Li J,Chen G,Huang G,Fu Q,Wang C,Chen L

更新日期：2019-03-22 00:00:00