Predicting cardiovascular disease morbidity and mortality in chronic kidney disease in Spain. The rationale and design of NEFRONA: a prospective, multicenter, observational cohort study.

abstract：BACKGROUND:Several equations have been developed to estimate glomerular filtration rate (eGFR). The common equations used were derived from populations predominantly comprised of Caucasians with chronic kidney disease (CKD). Some of the equations provide a correction factor for African-Americans due to their relatively...

journal_title：BMC nephrology

authors： Omuse G,Maina D,Mwangi J,Wambua C,Kanyua A,Kagotho E,Amayo A,Ojwang P,Erasmus R

更新日期：2017-12-20 00:00:00

abstract：BACKGROUND:Seasonal mortality differences have been reported in US hemodialysis (HD) patients. Here we examine the effect of seasons on mortality, clinical and laboratory parameters on a global scale. METHODS:Databases from the international Monitoring Dialysis Outcomes (MONDO) consortium were queried to identify pati...

journal_title：BMC nephrology

authors： Guinsburg AM,Usvyat LA,Etter M,Xu X,Thijssen S,Marcelli D,Canaud B,Marelli C,Barth C,Wang Y,Carioni P,van der Sande FM,Kotanko P,Kooman JP,Monitoring Dialysis Outcomes (MONDO) consortium.

更新日期：2015-08-14 00:00:00

abstract：BACKGROUND:MicroRNAs have been demonstrated to play an important role in the pathogenesis of diabetic nephropathy (DN). In this study, we investigated both the repertoire of miRNAs in the kidneys of patients with DN and their potential regulatory role in inflammation-mediated glomerular endothelial injury. METHODS:The...

journal_title：BMC nephrology

authors： Huang Y,Liu Y,Li L,Su B,Yang L,Fan W,Yin Q,Chen L,Cui T,Zhang J,Lu Y,Cheng J,Fu P,Liu F

更新日期：2014-09-02 00:00:00

abstract：BACKGROUND:Hypertension is a public health problem with mostly unknown causes, and where strong hereditary genetic alterations have not been fully elucidated. However, the use of experimental models has provided valuable information. Recent evidences suggest that alterations in key nephrogenic factors, such as Wilms' t...

journal_title：BMC nephrology

authors： Mazzei L,García M,Calvo JP,Casarotto M,Fornés M,Abud MA,Cuello-Carrión D,Ferder L,Manucha W

更新日期：2016-03-24 00:00:00

abstract：BACKGROUND:Local renal ischemia is regarded as an important factor in the development of contrast-induced nephropathy (CIN). Mannose-binding lectin (MBL) is involved in the tissue damage during experimental ischemia/reperfusion injury of the kidneys. The aim of the present study was to investigate the association of MB...

journal_title：BMC nephrology

authors： Osthoff M,Piezzi V,Klima T,Christ A,Marana I,Hartwiger S,Breidthardt T,Marenzi G,Trendelenburg M,Mueller C

更新日期：2012-09-03 00:00:00

abstract：BACKGROUND:Immunoglobulin light chains are classified as middle molecule uremic toxins able to interact with B lymphocyte membranes leading to the activation of transmembrane signaling. The ensuing impairment of neutrophil function can contribute to the chronic inflammation state of uremic patients, and the increased r...

journal_title：BMC nephrology

authors： Donati G,Moretti MI,Baraldi O,Spazzoli A,Capelli I,Comai G,Marchetti A,Sarma M,Mancini R,La Manna G

更新日期：2016-11-25 00:00:00

abstract：BACKGROUND:Chronic kidney disease (CKD) is characterized by dysbiosis, elevated levels of uremic toxins, systemic inflammation, and increased markers of oxidative stress. These factors lead to an increased risk of cardiovascular disease (CVD) which is common among CKD patients. Supplementation with high amylose maize r...

journal_title：BMC nephrology

authors： Headley SA,Chapman DJ,Germain MJ,Evans EE,Hutchinson J,Madsen KL,Ikizler TA,Miele EM,Kirton K,O'Neill E,Cornelius A,Martin B,Nindl B,Vaziri ND

更新日期：2020-11-26 00:00:00

abstract：BACKGROUND:Providing patient-centered care needs in patients with chronic renal failure undergoing hemodialysis is important in inspiring their confidence to continue their treatment and promote their mental and social health. Therefore, recognizing the concept of care from the viewpoint of these patients can be helpfu...

journal_title：BMC nephrology

authors： Shahgholian N,Yousefi H

更新日期：2018-11-26 00:00:00

abstract：BACKGROUND:Early recognition and management of chronic kidney disease (CKD) are associated with better outcomes. Internal medicine residency should prepare physicians to diagnose and manage CKD. METHODS:To examine whether residency training and program characteristics were associated with CKD knowledge and investigate...

journal_title：BMC nephrology

authors： Estrella MM,Sisson SD,Roth J,Choi MJ

更新日期：2012-09-27 00:00:00

abstract：BACKGROUND:Dietary and lifestyle factors may play an important role in the increasing prevalence of nephrolithiasis. We aimed to review and quantify the associations between lifestyle factors and incident nephrolithiasis and suggest lifestyle changes for the primary prevention of nephrolithiasis. METHODS:PubMed, EMBAS...

journal_title：BMC nephrology

authors： Lin BB,Lin ME,Huang RH,Hong YK,Lin BL,He XJ

更新日期：2020-07-11 00:00:00

abstract：BACKGROUND:Pyrrolidine dithiocarbamate (PDTC) reduces renal cyst growth in a rodent model of polycystic kidney disease (PKD) but the mechanism of action is not clear. Here, we investigated the hypothesis that PDTC reduces the proliferation of cystic epithelial cells in vitro in a nuclear factor (NF)-κB-dependent manner...

journal_title：BMC nephrology

authors： Ta MH,Liuwantara D,Rangan GK

更新日期：2015-12-15 00:00:00

abstract：BACKGROUND:Renal involvement in patients with chronic hepatitis C virus infection has been suggested to be due to a variety of immunological processes. However, the precise mechanism by which the kidneys are damaged in these patients is still unclear. CASE PRESENTATION:A 66 year old man presented with the sudden onset...

journal_title：BMC nephrology

authors： Ohsawa I,Uehara Y,Hashimoto S,Endo M,Fujita T,Ohi H

更新日期：2003-08-29 00:00:00

abstract：BACKGROUND:Adult patients with minimal change nephrotic syndrome (MCNS) are often associated with acute kidney injury (AKI). To assess the mechanisms of AKI, we examined whether tubular cell injuries unique to MCNS patients exist. METHODS:We performed a retrospective analysis of clinical data and tubular cell changes ...

journal_title：BMC nephrology

authors： Fujigaki Y,Tamura Y,Nagura M,Arai S,Ota T,Shibata S,Kondo F,Yamaguchi Y,Uchida S

更新日期：2017-11-28 00:00:00

abstract：BACKGROUND:The aims of this study are to find the prevalence of potential drug-drug interactions (DDIs) in patients with Hemodialysis and identify factors associated with these interactions if present. METHODS:The study was an observational- retrospective cohort study that was conducted in ten hemodialysis units in th...

journal_title：BMC nephrology

authors： Al-Ramahi R,Raddad AR,Rashed AO,Bsharat A,Abu-Ghazaleh D,Yasin E,Shehab O

更新日期：2016-07-26 00:00:00

abstract：:Attention has recently been focused on addressing the problem of acute kidney injury in both the developed and developing world. Little information is actually available on the incidence and management of AKI in low resource settings. Thus, the paper by Bagasha in the current issue of BMC Nephrology makes an important...

journal_title：BMC nephrology

authors： Anand S,Cruz DN,Finkelstein FO

更新日期：2015-01-16 00:00:00

abstract：BACKGROUND:A positive pregnancy test in acute or chronically ill patients has implications for the use of potentially mutagenic or teratogenic products in urgent medical therapies such as the use of chemotherapies or therapies with immunosuppressants, for anesthesia, and for time-sensitive indications like urgent surge...

journal_title：BMC nephrology

authors： Haninger-Vacariu N,Herkner H,Lorenz M,Säemann M,Vychytil A,Jansen M,Marculescu R,Kramar R,Sunder-Plassmann G,Schmidt A

更新日期：2020-02-28 00:00:00

abstract：BACKGROUND:Data on radial access (RA) as an independent risk factor for acute kidney injury (AKI) in myocardial infarction (MI) patients are conflicting. Our aim was to assess how RA influences the incidence of AKI in MI patients undergoing percutaneous coronary intervention (PCI). METHODS:Data from 3842 MI patients u...

journal_title：BMC nephrology

authors： Kanic V,Kompara G,Šuran D,Tapajner A,Naji FH,Sinkovic A

更新日期：2019-01-30 00:00:00

abstract：BACKGROUND:Acute kidney injury (AKI) is a serious clinical problem with high rate of mortality and morbidity. Currently used prophylactic and therapeutic strategies to address AKI are limited and warrant further studies. In the present study an attempt was made to investigate the effect of quinacrine, a phospholipase A...

journal_title：BMC nephrology

authors： Al Asmari AK,Al Sadoon KT,Obaid AA,Yesunayagam D,Tariq M

更新日期：2017-01-28 00:00:00

abstract：BACKGROUND:Galectin-9 (Gal-9) induces apoptosis in activated T helper 1 (TH1) cells as a ligand for T cell immunoglobulin mucin-3 (Tim-3). Gal-9 also inhibits the G1 phase cell cycle arrest and hypertrophy in db/db mice, the hallmark of early diabetic nephropathy, by reversing the high glucose-induced up-regulation of ...

journal_title：BMC nephrology

authors： Kurose Y,Wada J,Kanzaki M,Teshigawara S,Nakatsuka A,Murakami K,Inoue K,Terami T,Katayama A,Watanabe M,Higuchi C,Eguchi J,Miyatake N,Makino H

更新日期：2013-01-22 00:00:00

abstract：BACKGROUND:The optimal revascularization strategy for patients with impaired glomerular filtration rate (IGFR) has not been established in acute coronary syndrome (ACS). We investigated the prognosis and impact of IGFR and invasive strategy on the cardiovascular outcomes in the ACS population. METHODS:In a Taiwan nati...

journal_title：BMC nephrology

authors： Lin TH,Hsin HT,Wang CL,Lai WT,Li AH,Kuo CT,Hwang JJ,Chiang FT,Chang SC,Chang CJ,Taiwan ACS Full Spectrum Registry Investigators.

更新日期：2014-04-23 00:00:00

abstract：BACKGROUND:Transfusion patterns are not well characterized in non-dialysis (ND) chronic kidney disease (CKD) patients. This study describes the proportion of patients transfused, units of blood transfused and trigger-hemoglobin (Hb) levels for transfusions in severe anemic, ND-CKD patients in routine practice. METHODS...

journal_title：BMC nephrology

authors： Fox KM,Yee J,Cong Z,Brooks JM,Petersen J,Lamerato L,Gandra SR

更新日期：2012-01-24 00:00:00

abstract：BACKGROUND:Awareness of the spectrum of clinical manifestations of systemic lupus erythematosus (SLE), especially uncommon changes, is essential for diagnosis and effective management of patients. CASE PRESENTATION:A 26-year-old Chinese man with SLE initially manifested cutaneous papulonodular mucinosis and developed ...

journal_title：BMC nephrology

authors： Su X,Qiao X,Li J,Gao L,Wang C,Wang L

更新日期：2017-02-01 00:00:00

abstract：BACKGROUND:Both dialysis facilities and hospitals are accountable for 30-day hospital readmissions among U.S. hemodialysis patients. We examined the association of post-hospitalization processes of care at hemodialysis facilities with pulmonary edema-related and other readmissions. METHODS:In a retrospective cohort co...

journal_title：BMC nephrology

authors： Plantinga LC,Masud T,Lea JP,Burkart JM,O'Donnell CM,Jaar BG

更新日期：2018-07-31 00:00:00

abstract：BACKGROUND:Neutrophil gelatinase associated lipocalin (NGAL) is a highly predictive biomarker of acute kidney injury. To understand the role of NGAL in renal injury during sepsis, we investigated the temporal changes and biological sources of NGAL in a rat model of acute kidney injury, and explored the relationship bet...

journal_title：BMC nephrology

authors： Han M,Li Y,Liu M,Li Y,Cong B

更新日期：2012-06-27 00:00:00

abstract：BACKGROUND:Complementary and Alternative Medicines (CAMs) are increasingly practiced in the general population; it is estimated that over 30% of patients with chronic diseases use CAMs on a regular basis. CAMs are also used in hospital settings, suggesting a growing interest in individualized therapies. One potential f...

journal_title：BMC nephrology

authors： Ferraresi M,Clari R,Moro I,Banino E,Boero E,Crosio A,Dayne R,Rosset L,Scarpa A,Serra E,Surace A,Testore A,Colombi N,Piccoli BG

更新日期：2013-06-21 00:00:00

abstract：BACKGROUND:Sickle cell trait is not completely benign, and some renal complications can occur. The baseline rate of admission for gross hematuria in normal males carrying the sickle cell trait is 2%. CASE PRESENTATION:A 35-year-old non-smoking African man experienced a 2-week history of painless, profuse and persisten...

journal_title：BMC nephrology

authors： Le Joncour A,Mesnard L,Hertig A,Robert T

更新日期：2018-06-08 00:00:00

abstract：BACKGROUND:Nasal colonization with methicillin-resistant Staphylococcus aureus (MRSA) is a well defined risk factor for subsequent bacteremia and death in various groups of patients, but its impact on outcome in patients receiving long-term hemodialysis (HD) is under debate. METHODS:This prospective interventional coh...

journal_title：BMC nephrology

authors： Schmid H,Romanos A,Schiffl H,Lederer SR

更新日期：2013-04-23 00:00:00

abstract：BACKGROUND:Polycystic Kidney Disease (PKD) kidneys exhibit increased extracellular matrix (ECM) collagen expression and metalloproteinases (MMPs) activity. We investigated the role of these increases on cystic disease progression in PKD kidneys. METHODS:We examined the role of type I collagen (collagen I) and membrane...

journal_title：BMC nephrology

authors： Liu B,Li C,Liu Z,Dai Z,Tao Y

更新日期：2012-09-11 00:00:00

abstract：BACKGROUND:TAFRO syndrome is a clinical subtype of idiopathic multicentric Castleman disease (iMCD) that is characterized by thrombocytopenia, anasarca, fever, reticulin myelofibrosis (or renal dysfunction), and organomegaly. TAFRO syndrome has only recently been described, and many clinicians are unaware of this disea...

journal_title：BMC nephrology

authors： Zhou Q,Zhang Y,Zhou G,Zhu J

更新日期：2020-11-23 00:00:00

abstract：BACKGROUND:Chronic kidney disease (CKD) is an independent risk factor for cardiovascular disease (CVD) events, and a number of reports have shown a relationship between CKD and CVD in pre-dialysis or maintenance dialysis patients. However, few studies have reported serial observations during dialysis initiation and mai...

journal_title：BMC nephrology

authors： Inaguma D,Koide S,Takahashi K,Hayashi H,Hasegawa M,Yuzawa Y

更新日期：2017-02-28 00:00:00