Abstract：
BACKGROUND:Early recognition and management of chronic kidney disease (CKD) are associated with better outcomes. Internal medicine residency should prepare physicians to diagnose and manage CKD. METHODS:To examine whether residency training and program characteristics were associated with CKD knowledge and investigate the effectiveness of an internet-based training module in improving CKD knowledge, we analyzed data from CKD training modules administered annually to U.S. internal medicine residents from July 1, 2005 to June 30, 2009. Baseline CKD knowledge was assessed using pre-tests. The modules' effectiveness was evaluated by post-tests. Comparisons were performed using X² tests and paired t-tests. RESULTS:Of 4,702 residents, 38%, 33%, and 29% were program year (PGY)-1, PGY-2, and PGY-3, respectively. Baseline CKD knowledge was poor, with mean pre-test scores of 45.1-57.0% across the four years. The lowest pre-test performance was on CKD recognition. Pre-test scores were better with higher training levels (P-trend < 0.001 except 2005-2006 [P-trend = 0.35]). Affiliation with a renal fellowship program or program location within a region of high end-stage kidney disease prevalence was not associated with better baseline CKD knowledge. Completion of the CKD module led to significant improvements from pre- to post-test scores (mean improvement 27.8% [SD: 21.3%] which were consistent from 2005 to 2009. CONCLUSIONS:Knowledge of diagnosis and management of CKD improves during residency training but remains poor among graduating residents. Web-based training can be effective in educating physicians on CKD-related issues. Studies are needed to determine whether knowledge gained from such an intervention translates to improved care of CKD patients.
journal_name
BMC Nephroljournal_title
BMC nephrologyauthors
Estrella MM,Sisson SD,Roth J,Choi MJdoi
10.1186/1471-2369-13-126subject
Has Abstractpub_date
2012-09-27 00:00:00pages
126issn
1471-2369pii
1471-2369-13-126journal_volume
13pub_type
杂志文章相关文献
BMC Nephrology文献大全abstract：BACKGROUND:Chronic active antibody-mediated rejection is a major etiology of graft loss in renal transplant recipients. However, there is no consensus on the optimal treatment strategies. METHODS:Computerized records from Taichung Veterans General Hospital were collected to identify renal transplant biopsies performed...
journal_title：BMC nephrology
pub_type： 杂志文章
doi：10.1186/s12882-019-1672-8
更新日期：2020-01-06 00:00:00
abstract：BACKGROUND:To identify patient and health system characteristics associated with late referral of patients with chronic kidney disease to nephrologists. METHODS:MEDLINE, CENTRAL, and CINAHL were searched using the appropriate MESH terms in March 2007. Two reviewers individually and in duplicate reviewed the abstracts ...
journal_title：BMC nephrology
pub_type： 杂志文章,评审
doi：10.1186/1471-2369-9-3
更新日期：2008-02-25 00:00:00
abstract：BACKGROUND:Interleukin 17 is a proinflammatory cytokine involved in immune response after allograft transplantation. IL-17 family of proinflammatory cytokines includes IL-17A and IL-17F. Previous studies have demonstrated that the rs2275913 IL17A and the rs11465553 IL17F gene polymorphism are associated with kidney all...
journal_title：BMC nephrology
pub_type： 杂志文章
doi：10.1186/s12882-019-1308-z
更新日期：2019-04-08 00:00:00
abstract：BACKGROUND:Autosomal dominant polycystic kidney disease (ADPKD) is a hereditary disease characterized by the presence of renal cysts. Over time the expanding cysts lead to progressive renal failure. The use of tolvaptan, a V2-receptor antagonist, was recently approved in ADPKD patients. It was demonstrated that tolvapt...
journal_title：BMC nephrology
pub_type： 杂志文章
doi：10.1186/s12882-019-1612-7
更新日期：2019-11-21 00:00:00
abstract：BACKGROUND:Dietary and lifestyle factors may play an important role in the increasing prevalence of nephrolithiasis. We aimed to review and quantify the associations between lifestyle factors and incident nephrolithiasis and suggest lifestyle changes for the primary prevention of nephrolithiasis. METHODS:PubMed, EMBAS...
journal_title：BMC nephrology
pub_type： 杂志文章
doi：10.1186/s12882-020-01925-3
更新日期：2020-07-11 00:00:00
abstract：BACKGROUND:The current practice concerning timing, mode, and dose of renal replacement therapy (RRT) in patients with metformin-associated lactic acidosis (MALA) with renal failure remains unknown. To investigate whether serum lactate level and prescription pattern of RRT are associated with mortality in patients with ...
journal_title：BMC nephrology
pub_type： 杂志文章,评审
doi：10.1186/s12882-017-0640-4
更新日期：2017-07-10 00:00:00
abstract：BACKGROUND:Chronic kidney disease (CKD) with edema is a common clinical problem resulting from defects in water and solute excretion. Furosemide is the drug of choice for treatment. In theory, good perfusion and albumin are required for the furosemide to be secreted at the tubular lumen. Thus, in the situation of low g...
journal_title：BMC nephrology
pub_type： 杂志文章,随机对照试验
doi：10.1186/1471-2369-13-92
更新日期：2012-08-29 00:00:00
abstract：BACKGROUND:There is a high prevalence of cognitive impairment in dialysis patients. The prevalence of cognitive impairment after kidney transplantation is unknown. METHODS:Study Design: Cross-sectional study. SETTING AND PARTICIPANTS:Single center study of prevalent kidney transplant recipients from a transplant clin...
journal_title：BMC nephrology
pub_type： 杂志文章
doi：10.1186/s12882-017-0570-1
更新日期：2017-05-12 00:00:00
abstract：BACKGROUND:Accurate estimation of glomerular filtration rate (GFR) is important for diagnosis and risk stratification in chronic kidney disease and for selection of living donors. Ethnic differences have required correction factors in the originally developed creatinine-based GFR estimation equations for populations ar...
journal_title：BMC nephrology
pub_type： 杂志文章
doi：10.1186/s12882-018-0813-9
更新日期：2018-02-01 00:00:00
abstract：BACKGROUND:Patients who start renal replacement therapy (RRT) for End-Stage Kidney Disease (ESKD) without having had timely access to specialist renal services have poor outcomes. At one NHS Trust in England, a community-wide CKD management system has led to a decline in the incident rate of RRT and the lowest percenta...
journal_title：BMC nephrology
pub_type： 杂志文章,随机对照试验
doi：10.1186/s12882-017-0522-9
更新日期：2017-04-11 00:00:00
abstract：BACKGROUND:S100A12 protein is an endogenous receptor ligand for advanced glycation end products. In this study, the plasma S100A12 level was assessed as an independent predictor of mortality, and its utility in clinical settings was examined. METHODS:In a previous cross-sectional study, plasma S100A12 levels were meas...
journal_title：BMC nephrology
pub_type： 临床试验,杂志文章,多中心研究
doi：10.1186/1471-2369-14-16
更新日期：2013-01-16 00:00:00
abstract：BACKGROUND:Neutrophil gelatinase associated lipocalin (NGAL) is a highly predictive biomarker of acute kidney injury. To understand the role of NGAL in renal injury during sepsis, we investigated the temporal changes and biological sources of NGAL in a rat model of acute kidney injury, and explored the relationship bet...
journal_title：BMC nephrology
pub_type： 杂志文章
doi：10.1186/1471-2369-13-25
更新日期：2012-06-27 00:00:00
abstract：BACKGROUND:Rehabilitation effects of exercise training on adults with chronic kidney disease (CKD) have been generally recognised; however, the effects of exercise training on proteinuria have been underexplored. Our aim was to explore the effects of exercise training on proteinuria in adult CKD patients without renal ...
journal_title：BMC nephrology
pub_type： 杂志文章
doi：10.1186/s12882-020-01816-7
更新日期：2020-05-11 00:00:00
abstract：BACKGROUND:Evidence suggests that exercise training for hemodialysis patients positively improves morbidity and mortality outcomes, yet exercise programs remain rare and are not systematically incorporated into care. We developed a research-based film, Fit for Dialysis, designed to introduce, motivate, and sustain exer...
journal_title：BMC nephrology
pub_type： 杂志文章
doi：10.1186/s12882-017-0454-4
更新日期：2017-01-26 00:00:00
abstract：BACKGROUND:Seasonal mortality differences have been reported in US hemodialysis (HD) patients. Here we examine the effect of seasons on mortality, clinical and laboratory parameters on a global scale. METHODS:Databases from the international Monitoring Dialysis Outcomes (MONDO) consortium were queried to identify pati...
journal_title：BMC nephrology
pub_type： 杂志文章
doi：10.1186/s12882-015-0129-y
更新日期：2015-08-14 00:00:00
abstract：BACKGROUND:Pyrrolidine dithiocarbamate (PDTC) reduces renal cyst growth in a rodent model of polycystic kidney disease (PKD) but the mechanism of action is not clear. Here, we investigated the hypothesis that PDTC reduces the proliferation of cystic epithelial cells in vitro in a nuclear factor (NF)-κB-dependent manner...
journal_title：BMC nephrology
pub_type： 杂志文章
doi：10.1186/s12882-015-0193-3
更新日期：2015-12-15 00:00:00
abstract：BACKGROUND:Cystinuria is an inherited metabolic disease that is caused by defects in two genes, SLC3A1 and SLC7A9, which result in a renal reabsorptive defect of cystine and other dibasic amino acids, including ornithine, arginine, and lysine. Patients usually present with recurrent renal calculi and may develop renal ...
journal_title：BMC nephrology
pub_type： 杂志文章
doi：10.1186/s12882-017-0469-x
更新日期：2017-02-06 00:00:00
abstract：BACKGROUND:The poorly differentiated renal cell carcinoma (RCC) with rhabdomyosarcomatous sarcomatoid differentiation shows a severely aggressive biological behavior characterized by rapid disease progression. Preoperative identification of the subtype with the prognostic factors and imaging features of sarcomatoid ren...
journal_title：BMC nephrology
pub_type： 杂志文章,评审
doi：10.1186/s12882-018-0884-7
更新日期：2018-04-10 00:00:00
abstract：BACKGROUND:This study aimed to compare clinical features and health-related quality of life (HRQoL) in the Chinese chronic kidney disease (CKD) 3 population and determined the necessity of the subdivision of CKD3 in Chinese patients with CKD. METHODS:Participants with stage 3 CKD (18-74 years of age) were recruited at...
journal_title：BMC nephrology
pub_type： 杂志文章
doi：10.1186/s12882-017-0725-0
更新日期：2017-10-13 00:00:00
abstract：BACKGROUND:Dyspepsia is a common disorder in kidney transplant recipients, and the risk of post-transplant complications is increased in candidates with upper gastrointestinal disease. We evaluated gastrointestinal lesions of kidney transplant candidates on dialysis. METHODS:In this study, endoscopic and pathological ...
journal_title：BMC nephrology
pub_type： 杂志文章
doi：10.1186/s12882-020-02108-w
更新日期：2020-10-22 00:00:00
abstract：BACKGROUND:Evidence suggests that alkaline phosphatase attenuates inflammatory response in sepsis by lipopolysaccharide detoxification and adenosine triphosphate dephosphorylation. We sought to determine changes in alkaline phosphatase (AP) activity during septic acute kidney injury (AKI) and clinical parameters associ...
journal_title：BMC nephrology
pub_type： 杂志文章
doi：10.1186/s12882-018-1028-9
更新日期：2018-09-20 00:00:00
abstract：BACKGROUND:Both dialysis facilities and hospitals are accountable for 30-day hospital readmissions among U.S. hemodialysis patients. We examined the association of post-hospitalization processes of care at hemodialysis facilities with pulmonary edema-related and other readmissions. METHODS:In a retrospective cohort co...
journal_title：BMC nephrology
pub_type： 杂志文章
doi：10.1186/s12882-018-0983-5
更新日期：2018-07-31 00:00:00
abstract：BACKGROUND:Age and number of recipients in need of kidney re-transplantation are increasing. Re-transplantation practices and outcomes in elderly recipients are not previously explored. We aimed to retrospectively evaluate the outcomes of recipients 65 years and older receiving their second deceased donor allograft. M...
journal_title：BMC nephrology
pub_type： 杂志文章
doi：10.1186/s12882-016-0426-0
更新日期：2017-01-11 00:00:00
abstract：BACKGROUND:Transplant renal artery dissection is a rare and serious event that can cause allograft dysfunction and activation of the renin-mediated renovascular hypertension. Most cases are induced by percutaneous transluminal angioplasty, arteriosclerotic disease, or fibromuscular dysplasia. We observed a case of tran...
journal_title：BMC nephrology
pub_type： 杂志文章
doi：10.1186/s12882-020-1699-x
更新日期：2020-01-29 00:00:00
abstract：BACKGROUND:Major Depressive Disorder (MDD) can lead to adverse cardiovascular outcomes in patients with chronic kidney disease (CKD). Although one of the proposed mechanisms is heightened platelet activation, effects of MDD and its treatment with a selective serotonin reuptake inhibitor (SSRI) on platelet function in p...
journal_title：BMC nephrology
pub_type： 杂志文章,随机对照试验
doi：10.1186/s12882-019-1576-7
更新日期：2019-10-29 00:00:00
abstract：BACKGROUND:Urinary Ca2+ excretion increases with dietary NaCl. NaCl-induced calciuria may be associated with hypertension, urinary stone formation and osteoporosis, but its mechanism and long-term effects are not fully understood. This study examined alterations in the expressions of renal Ca2+ transporters, channels a...
journal_title：BMC nephrology
pub_type： 杂志文章
doi：10.1186/1471-2369-13-160
更新日期：2012-12-02 00:00:00
abstract：BACKGROUND:Chronic hepatitis B virus (HBV) infection and chronic kidney disease (CKD) have high prevalences in Taiwan and worldwide. However, the association of untreated chronic hepatitis B virus (HBV) infection with chronic kidney disease (CKD) remains unclear. METHODS:This cohort study used claims data in the Taiwa...
journal_title：BMC nephrology
pub_type： 杂志文章
doi：10.1186/s12882-015-0106-5
更新日期：2015-07-22 00:00:00
abstract：BACKGROUND:Association between metabolic syndrome (MS) and mildly reduced estimated glomerular filtration rates (eGFRs) remains unclear. Therefore, we aimed to evaluate the association between MS and a mildly reduced eGFR in Chinese adults. METHODS:Anthropometric and biochemical examinations were performed in 2992 ind...
journal_title：BMC nephrology
pub_type： 杂志文章
doi：10.1186/s12882-017-0597-3
更新日期：2017-06-13 00:00:00
abstract：BACKGROUND:Hyperchloremia is common in critically ill septic patients. The impact of hyperchloremia on the incidence of acute kidney injury (AKI) is not well studied. We investigated the association between hyperchloremia and AKI within the first 72 h of intensive care unit (ICU) admission. METHODS:6490 ICU adult pati...
journal_title：BMC nephrology
pub_type： 杂志文章
doi：10.1186/s12882-017-0750-z
更新日期：2017-12-02 00:00:00
abstract：BACKGROUND:Decreased heat shock protein 27 (HSP27) participates in many processes that are involved in cardiovascular (CV) disease. The objective of the study was to evaluate if HSP27 level was predictive of mortality as well as to evaluate factors associated with HSP27 level in a group of patients treated with HD. ME...
journal_title：BMC nephrology
pub_type： 杂志文章
doi：10.1186/s12882-018-1157-1
更新日期：2018-12-17 00:00:00
