Seasonal variations in mortality and clinical indicators in international hemodialysis populations from the MONDO registry.

Abstract:

BACKGROUND:Seasonal mortality differences have been reported in US hemodialysis (HD) patients. Here we examine the effect of seasons on mortality, clinical and laboratory parameters on a global scale. METHODS:Databases from the international Monitoring Dialysis Outcomes (MONDO) consortium were queried to identify patients who received in-center HD for at least 1 year. Clinics were stratified by hemisphere and climate zone (tropical or temperate). We recorded mortality and computed averages of pre-dialysis systolic blood pressure (pre-SBP), interdialytic weight gain (IDWG), serum albumin, and log C-reactive protein (CRP). We explored seasonal effects using cosinor analysis and adjusted linear mixed models globally, and after stratification. RESULTS:Data from 87,399 patients were included (northern temperate: 63,671; northern tropical: 7,159; southern temperate: 13,917; southern tropical: 2,652 patients). Globally, mortality was highest in winter. Following stratification, mortality was significantly lower in spring and summer compared to winter in temperate, but not in tropical zones. Globally, pre-SBP and IDWG were lower in summer and spring as compared to winter, although less pronounced in tropical zones. Except for southern temperate zone, serum albumin levels were higher in winter. CRP levels were highest in winter. CONCLUSION:Significant global seasonal variations in mortality, pre-SBP, IDWG, albumin and CRP were observed. Seasonal variations in mortality were most pronounced in temperate climate zones.

journal_name

BMC Nephrol

journal_title

BMC nephrology

authors

Guinsburg AM,Usvyat LA,Etter M,Xu X,Thijssen S,Marcelli D,Canaud B,Marelli C,Barth C,Wang Y,Carioni P,van der Sande FM,Kotanko P,Kooman JP,Monitoring Dialysis Outcomes (MONDO) consortium.

doi

10.1186/s12882-015-0129-y

subject

Has Abstract

pub_date

2015-08-14 00:00:00

pages

139

issn

1471-2369

pii

10.1186/s12882-015-0129-y

journal_volume

16

pub_type

杂志文章
  • Liddle's-like syndrome associated with nephrotic syndrome secondary to membranous nephropathy: the first case report.

    abstract:BACKGROUND:Liddle's syndrome is a rare monogenic form of hypertension caused by truncating or missense mutations in the C termini of the epithelial sodium channel (ENaC) β or γ subunits. Patients with this syndrome present with early onset of hypertension, hypokalemia, metabolic alkalosis, hyporeninemia and hypoaldoste...

    journal_title:BMC nephrology

    pub_type: 杂志文章

    doi:10.1186/s12882-018-0916-3

    authors: Yamaguchi E,Yoshikawa K,Nakaya I,Kato K,Miyasato Y,Nakagawa T,Kakizoe Y,Mukoyama M,Soma J

    更新日期:2018-05-23 00:00:00

  • Association of functional and structural social support with chronic kidney disease among African Americans: the Jackson Heart Study.

    abstract:BACKGROUND:There is limited evidence on the relationship between social support and renal outcomes in African Americans. We sought to determine the association of social support with prevalent chronic kidney disease (CKD) and kidney function decline in an African American cohort. We also examined whether age modifies t...

    journal_title:BMC nephrology

    pub_type: 杂志文章

    doi:10.1186/s12882-019-1432-9

    authors: Hall RK,Davenport CA,Sims M,Colón-Emeric C,Washington T,St Clair Russell J,Pendergast J,Bhavsar N,Scialla J,Tyson CC,Wang W,Min YI,Young B,Boulware LE,Diamantidis CJ

    更新日期:2019-07-15 00:00:00

  • Clinical features and CKD-related quality of life in patients with CKD G3a and CKD G3b in China: results from the Chinese Cohort Study of Chronic Kidney Disease (C-STRIDE).

    abstract:BACKGROUND:This study aimed to compare clinical features and health-related quality of life (HRQoL) in the Chinese chronic kidney disease (CKD) 3 population and determined the necessity of the subdivision of CKD3 in Chinese patients with CKD. METHODS:Participants with stage 3 CKD (18-74 years of age) were recruited at...

    journal_title:BMC nephrology

    pub_type: 杂志文章

    doi:10.1186/s12882-017-0725-0

    authors: Peng Z,Wang J,Yuan Q,Xiao X,Xu H,Xie Y,Wang W,Huang L,Zhong Y,Ao X,Zhang L,Zhao M,Tao L,Zhou Q,C-STRIDE study group.

    更新日期:2017-10-13 00:00:00

  • Early detection and intervention using neutrophil gelatinase-associated lipocalin (NGAL) may improve renal outcome of acute contrast media induced nephropathy: a randomized controlled trial in patients undergoing intra-arterial angiography (ANTI-CIN Study

    abstract:BACKGROUND:Patients with pre-existing impaired renal function are prone to develop acute contrast media induced nephropathy (CIN). Neutrophil gelatinase-associated lipocalin (NGAL), a new biomarker predictive for acute kidney injury (AKI), has been shown to be useful for earlier diagnosis of CIN; however, urinary NGAL ...

    journal_title:BMC nephrology

    pub_type: 杂志文章,随机对照试验

    doi:10.1186/1471-2369-12-39

    authors: Schilcher G,Ribitsch W,Otto R,Portugaller RH,Quehenberger F,Truschnig-Wilders M,Zweiker R,Stiegler P,Brodmann M,Weinhandl K,Horina JH

    更新日期:2011-08-17 00:00:00

  • Blood oxygen level dependent magnetic resonance imaging for detecting pathological patterns in lupus nephritis patients: a preliminary study using a decision tree model.

    abstract:BACKGROUND:Precise renal histopathological diagnosis will guide therapy strategy in patients with lupus nephritis. Blood oxygen level dependent (BOLD) magnetic resonance imaging (MRI) has been applicable noninvasive technique in renal disease. This current study was performed to explore whether BOLD MRI could contribut...

    journal_title:BMC nephrology

    pub_type: 杂志文章

    doi:10.1186/s12882-017-0787-z

    authors: Shi H,Jia J,Li D,Wei L,Shang W,Zheng Z

    更新日期:2018-02-09 00:00:00

  • Complement activation products in the circulation and urine of primary membranous nephropathy.

    abstract:BACKGROUND:Complement activation plays a substantial role in the pathogenesis of primary membranous nephropathy (pMN). C5b-9, C3c, MBL, and factor B have been documented in the subepithelial immune deposits. However, the changing of complement activation products in circulation and urine is not clear. METHODS:We measu...

    journal_title:BMC nephrology

    pub_type: 杂志文章

    doi:10.1186/s12882-019-1509-5

    authors: Zhang MF,Huang J,Zhang YM,Qu Z,Wang X,Wang F,Meng LQ,Cheng XY,Cui Z,Liu G,Zhao MH

    更新日期:2019-08-09 00:00:00

  • Fractional excretion of IgG in idiopathic membranous nephropathy with nephrotic syndrome: a predictive marker of risk and drug responsiveness.

    abstract:BACKGROUND:Treatment of idiopathic membranous nephropathy with nephrotic syndrome is still controversial. There is currently little known about the clinical use of renal biomarkers which may explain contradictory results obtained from clinical trials. In order to assess whether IgG-uria can predict the outcome in membr...

    journal_title:BMC nephrology

    pub_type: 临床试验,杂志文章

    doi:10.1186/1471-2369-15-74

    authors: Bazzi C,Rizza V,Casellato D,Tofik R,Berg AL,Gallieni M,D'Amico G,Bakoush O

    更新日期:2014-05-08 00:00:00

  • A programme to spread eGFR graph surveillance for the early identification, support and treatment of people with progressive chronic kidney disease (ASSIST-CKD): protocol for the stepped wedge implementation and evaluation of an intervention to reduce lat

    abstract:BACKGROUND:Patients who start renal replacement therapy (RRT) for End-Stage Kidney Disease (ESKD) without having had timely access to specialist renal services have poor outcomes. At one NHS Trust in England, a community-wide CKD management system has led to a decline in the incident rate of RRT and the lowest percenta...

    journal_title:BMC nephrology

    pub_type: 杂志文章,随机对照试验

    doi:10.1186/s12882-017-0522-9

    authors: Gallagher H,Methven S,Casula A,Thomas N,Tomson CR,Caskey FJ,Rose T,Walters SJ,Kennedy D,Dawnay A,Cassidy M,Fluck R,Rayner HC,Nation M

    更新日期:2017-04-11 00:00:00

  • Age differences in the relationships between risk factors and loss of kidney function: a general population cohort study.

    abstract:BACKGROUND:Annual decline in kidney function is a widely applied surrogate outcome of renal failure. It is important to understand the relationships between known risk factors and the annual decline in estimated glomerular filtration rate (eGFR) according to baseline age; however, these remain unclear. METHODS:A commu...

    journal_title:BMC nephrology

    pub_type: 杂志文章

    doi:10.1186/s12882-020-02121-z

    authors: Toyama T,Kitagawa K,Oshima M,Kitajima S,Hara A,Iwata Y,Sakai N,Shimizu M,Hashiba A,Furuichi K,Wada T

    更新日期:2020-11-13 00:00:00

  • Analysis of kidney dysfunction in orthopaedic patients.

    abstract:BACKGROUND:This retrospective study was undertaken to determine the incidence of kidney dysfunction (KD) and to identify potential risk factors contributing to development of KD in orthopaedic population following an elective or emergency surgery. METHODS:A total of 1025 patients were admitted in our institution over ...

    journal_title:BMC nephrology

    pub_type: 杂志文章

    doi:10.1186/1471-2369-13-101

    authors: Kateros K,Doulgerakis C,Galanakos SP,Sakellariou VI,Papadakis SA,Macheras GA

    更新日期:2012-09-03 00:00:00

  • Hyperphosphatemia and risks of acute kidney injury, end-stage renal disease, and mortality in hospitalized patients.

    abstract:BACKGROUND:Hyperphosphatemia is associated with vascular calcification and bone mineral disorders and is a major concern among patients with chronic kidney disease (CKD). However, the relationship between hyperphosphatemia and renal outcome in non-CKD patients has not been studied. Furthermore, the clinical implication...

    journal_title:BMC nephrology

    pub_type: 杂志文章

    doi:10.1186/s12882-019-1556-y

    authors: Moon H,Chin HJ,Na KY,Joo KW,Kim YS,Kim S,Han SS

    更新日期:2019-09-18 00:00:00

  • Designing a web-application to support home-based care of childhood CKD stages 3-5: qualitative study of family and professional preferences.

    abstract:BACKGROUND:There is a lack of online, evidence-based information and resources to support home-based care of childhood CKD stages 3-5. METHODS:Qualitative interviews were undertaken with parents, patients and professionals to explore their views on content of the proposed online parent information and support (OPIS) w...

    journal_title:BMC nephrology

    pub_type: 杂志文章

    doi:10.1186/1471-2369-15-34

    authors: Swallow VM,Hall AG,Carolan I,Santacroce S,Webb NJ,Smith T,Hanif N

    更新日期:2014-02-18 00:00:00

  • Gitelman-like syndrome after cisplatin therapy: a case report and literature review.

    abstract:BACKGROUND:Cisplatin is a well-known nephrotoxic antineoplastic drug. Chronic hypokalemic metabolic alkalosis with hypomagnesemia and hypocalciuria is one of the rare complications associated with its use. CASE PRESENTATION:A 42-year-old woman presented with a 20 year-history of hypokalemic metabolic alkalosis with hy...

    journal_title:BMC nephrology

    pub_type: 杂志文章,评审

    doi:10.1186/1471-2369-7-10

    authors: Panichpisal K,Angulo-Pernett F,Selhi S,Nugent KM

    更新日期:2006-05-24 00:00:00

  • Acute kidney injury among critically ill patients with pandemic H1N1 influenza A in Canada: cohort study.

    abstract:BACKGROUND:Canada's pandemic H1N1 influenza A (pH1N1) outbreak led to a high burden of critical illness. Our objective was to describe the incidence of AKI (acute kidney injury) in these patients and risk factors for AKI, renal replacement therapy (RRT), and mortality. METHODS:From a prospective cohort of critically i...

    journal_title:BMC nephrology

    pub_type: 杂志文章,多中心研究

    doi:10.1186/1471-2369-14-123

    authors: Bagshaw SM,Sood MM,Long J,Fowler RA,Adhikari NK,Canadian Critical Care Trials Group H1N1 Collaborative.

    更新日期:2013-06-13 00:00:00

  • Differential impact of smoking on mortality and kidney transplantation among adult Men and Women undergoing dialysis.

    abstract:BACKGROUND:The extent to which smoking contributes to adverse outcomes among men and women of all ages undergoing dialysis is uncertain. The objective of this study was to determine the differential impact of smoking on risks of mortality and kidney transplantation by age and by sex at dialysis initiation. METHODS:We ...

    journal_title:BMC nephrology

    pub_type: 杂志文章

    doi:10.1186/s12882-016-0311-x

    authors: Stack AG,Yermak D,Roche DG,Ferguson JP,Elsayed M,Mohammed W,Casserly LF,Walsh SR,Cronin CJ

    更新日期:2016-07-26 00:00:00

  • Prognostic utility of plasma S100A12 levels to establish a novel scoring system for predicting mortality in maintenance hemodialysis patients: a two-year prospective observational study in Japan.

    abstract:BACKGROUND:S100A12 protein is an endogenous receptor ligand for advanced glycation end products. In this study, the plasma S100A12 level was assessed as an independent predictor of mortality, and its utility in clinical settings was examined. METHODS:In a previous cross-sectional study, plasma S100A12 levels were meas...

    journal_title:BMC nephrology

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1186/1471-2369-14-16

    authors: Shiotsu Y,Mori Y,Nishimura M,Hatta T,Imada N,Maki N,Iida K,Iwamoto N,Matsuoka E,Tamagaki K,Kosaki A

    更新日期:2013-01-16 00:00:00

  • Effect of hyperchloremia on acute kidney injury in critically ill septic patients: a retrospective cohort study.

    abstract:BACKGROUND:Hyperchloremia is common in critically ill septic patients. The impact of hyperchloremia on the incidence of acute kidney injury (AKI) is not well studied. We investigated the association between hyperchloremia and AKI within the first 72 h of intensive care unit (ICU) admission. METHODS:6490 ICU adult pati...

    journal_title:BMC nephrology

    pub_type: 杂志文章

    doi:10.1186/s12882-017-0750-z

    authors: Yessayan L,Neyra JA,Canepa-Escaro F,Vasquez-Rios G,Heung M,Yee J,Acute Kidney Injury in Critical Illness Study Group.

    更新日期:2017-12-02 00:00:00

  • Removal of free light chains in hemodialysis patients without multiple myeloma: a crossover comparison of three different dialyzers.

    abstract:BACKGROUND:Immunoglobulin light chains are classified as middle molecule uremic toxins able to interact with B lymphocyte membranes leading to the activation of transmembrane signaling. The ensuing impairment of neutrophil function can contribute to the chronic inflammation state of uremic patients, and the increased r...

    journal_title:BMC nephrology

    pub_type: 杂志文章,随机对照试验

    doi:10.1186/s12882-016-0405-5

    authors: Donati G,Moretti MI,Baraldi O,Spazzoli A,Capelli I,Comai G,Marchetti A,Sarma M,Mancini R,La Manna G

    更新日期:2016-11-25 00:00:00

  • Arg913Gln variation of SLC12A3 gene is associated with diabetic nephropathy in type 2 diabetes and Gitelman syndrome: a systematic review.

    abstract:BACKGROUND:Diabetic nephropathy is a global common cause of chronic kidney disease and end-stage renal disease. A lot of research has been conducted in biomedical sciences, which has enhanced understanding of the pathophysiology of diabetic nephropathy and has expanded the potential available therapies. An increasing n...

    journal_title:BMC nephrology

    pub_type: 杂志文章

    doi:10.1186/s12882-019-1590-9

    authors: De la Cruz-Cano E,Jiménez-González CDC,Morales-García V,Pineda-Pérez C,Tejas-Juárez JG,Rendón-Gandarilla FJ,Jiménez-Morales S,Díaz-Gandarilla JA

    更新日期:2019-10-28 00:00:00

  • Transplantation and diabetes (Transdiab): a pilot randomised controlled trial of metformin in impaired glucose tolerance after kidney transplantation.

    abstract:BACKGROUND:Post transplantation diabetes mellitus (PTDM) is a common and serious complication after renal transplantation with significant morbidity and mortality. Metformin has proven benefits in the general population and might be advantageous in the prevention and management of PTDM. METHODS:Transplantation and Dia...

    journal_title:BMC nephrology

    pub_type: 杂志文章,随机对照试验

    doi:10.1186/s12882-019-1321-2

    authors: Alnasrallah B,Goh TL,Chan LW,Manley P,Pilmore H

    更新日期:2019-04-29 00:00:00

  • Association of Frailty based on self-reported physical function with directly measured kidney function and mortality.

    abstract:BACKGROUND:Use of serum creatinine to estimate GFR may lead to underestimation of the association between self-reported frailty and kidney function. Our objectives were to evaluate the association of measured GFR (mGFR) with self-reported frailty among patients with CKD and to determine whether self-reported frailty wa...

    journal_title:BMC nephrology

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1186/s12882-015-0202-6

    authors: Delgado C,Grimes BA,Glidden DV,Shlipak M,Sarnak MJ,Johansen KL

    更新日期:2015-12-09 00:00:00

  • Prevalence of chronic kidney disease and associated factors among the Chinese population in Taian, China.

    abstract:BACKGROUND:This study was designed to assess the prevalence of chronic kidney disease (CKD) and associated risk factors among the Chinese population in Taian, China. METHODS:A primary care-based cross-sectional study was conducted in Taian, China, from September to December 2012. Participants selected by a multi-stage...

    journal_title:BMC nephrology

    pub_type: 杂志文章

    doi:10.1186/1471-2369-15-205

    authors: Xue L,Lou Y,Feng X,Wang C,Ran Z,Zhang X

    更新日期:2014-12-21 00:00:00

  • A model to predict disease progression in patients with autosomal dominant polycystic kidney disease (ADPKD): the ADPKD Outcomes Model.

    abstract:BACKGROUND:Autosomal dominant polycystic kidney disease (ADPKD) is the leading inheritable cause of end-stage renal disease (ESRD); however, the natural course of disease progression is heterogeneous between patients. This study aimed to develop a natural history model of ADPKD that predicted progression rates and long...

    journal_title:BMC nephrology

    pub_type: 杂志文章

    doi:10.1186/s12882-017-0804-2

    authors: McEwan P,Bennett Wilton H,Ong ACM,Ørskov B,Sandford R,Scolari F,Cabrera MV,Walz G,O'Reilly K,Robinson P

    更新日期:2018-02-13 00:00:00

  • Understanding acute kidney injury in low resource settings: a step forward.

    abstract::Attention has recently been focused on addressing the problem of acute kidney injury in both the developed and developing world. Little information is actually available on the incidence and management of AKI in low resource settings. Thus, the paper by Bagasha in the current issue of BMC Nephrology makes an important...

    journal_title:BMC nephrology

    pub_type: 杂志文章

    doi:10.1186/1471-2369-16-5

    authors: Anand S,Cruz DN,Finkelstein FO

    更新日期:2015-01-16 00:00:00

  • Induction therapy with thymoglobulin or interleukin-2 receptor antagonist for Chinese recipients of living donor renal transplantation: a retrospective study.

    abstract:BACKGROUND:Recipients of living donor renal transplantation are typically considered to have a relatively lower immunological risk. This retrospective study aimed to compare the therapeutic efficacy and safety between rabbit antithymocyte globulin (rATG) or interleukin-2 receptor antagonist (IL2-RA) induction therapies...

    journal_title:BMC nephrology

    pub_type: 杂志文章

    doi:10.1186/s12882-019-1293-2

    authors: Qiu J,Li J,Chen G,Huang G,Fu Q,Wang C,Chen L

    更新日期:2019-03-22 00:00:00

  • Effects of exercise training on proteinuria in adult patients with chronic kidney disease: a systematic review and meta-analysis.

    abstract:BACKGROUND:Rehabilitation effects of exercise training on adults with chronic kidney disease (CKD) have been generally recognised; however, the effects of exercise training on proteinuria have been underexplored. Our aim was to explore the effects of exercise training on proteinuria in adult CKD patients without renal ...

    journal_title:BMC nephrology

    pub_type: 杂志文章

    doi:10.1186/s12882-020-01816-7

    authors: Yang L,Wu X,Wang Y,Wang C,Hu R,Wu Y

    更新日期:2020-05-11 00:00:00

  • PTGER3 and MMP-2 play potential roles in diabetic nephropathy via competing endogenous RNA mechanisms.

    abstract:BACKGROUND:Diabetic nephropathy (DN) is a primary complication of diabetes mellitus (DM). The pathology of DN is still vague, and diagnostic accuracy is not enough. This study was performed to identify miRNAs and genes that have possibilities of being used as therapeutic targets for DN in type 2 DM. METHODS:Human miRN...

    journal_title:BMC nephrology

    pub_type: 杂志文章

    doi:10.1186/s12882-020-02194-w

    authors: Yu Y,Jia YY,Wang M,Mu L,Li HJ

    更新日期:2021-01-12 00:00:00

  • Body weight definitions for evaluating a urinary diagnosis of acute kidney injury in patients with sepsis.

    abstract:BACKGROUND:We hypothesized that the use of actual body weight might lead to more frequent misdiagnosis of acute kidney injury (AKI) than when ideal body weight is used in underweight and/or obese patients. We examined which definition of body weight is most effective in establishing a urinary diagnosis of AKI in septic...

    journal_title:BMC nephrology

    pub_type: 杂志文章

    doi:10.1186/s12882-018-0895-4

    authors: Katayama S,Koyama K,Goto Y,Koinuma T,Tonai K,Shima J,Wada M,Nunomiya S

    更新日期:2018-05-02 00:00:00

  • Fibroblast growth factor 23 and parathyroid hormone after treatment with active vitamin D and sevelamer carbonate in patients with chronic kidney disease stage 3b, a randomized crossover trial.

    abstract:BACKGROUND:Fibroblast growth factor 23 (FGF23) is a phosphaturic hormone that is secreted from bone and serum level increases as renal function declines. Higher levels of FGF23 are associated with increased mortality in hemodialysis-patients and in patients with chronic kidney disease (CKD) stage 2-4. The use of active...

    journal_title:BMC nephrology

    pub_type: 杂志文章,随机对照试验

    doi:10.1186/1471-2369-13-49

    authors: Bleskestad IH,Bergrem H,Hartmann A,Godang K,Gøransson LG

    更新日期:2012-06-28 00:00:00

  • Serum cystatin C is a determinant of central pressure augmentation index measured by oscillometric method in renal transplant recipients.

    abstract:BACKGROUND:Serum cystatin C (ScysC) may help predicting cardiovascular outcome not only through its ability to detect renal dysfunction but also through its potential connection to others factors that are directly related to cardiovascular diseases. We explored the potential association of ScysC with arterial stiffness...

    journal_title:BMC nephrology

    pub_type: 杂志文章

    doi:10.1186/1471-2369-15-196

    authors: Dinic M,Maillard N,Thibaudin D,Jannot M,Masson I,Alamartine E,Mariat C

    更新日期:2014-12-11 00:00:00