The relation between dialysis-requiring acute kidney injury and recovery from end-stage renal disease: a national study.

abstract：BACKGROUND:Kidney injury molecule-1 (KIM-1) is a biomarker useful for detecting early tubular damage and has been recently reported as a useful marker for evaluating kidney injury in IgA nephropathy (IgAN). We therefore investigated whether treatment decreases urinary KIM-1 excretion in IgAN. METHODS:We prospectively ...

journal_title：BMC nephrology

authors： Seo MS,Park MY,Choi SJ,Jeon JS,Noh H,Kim JK,Han DC,Hwang SD,Jin SY,Kwon SH

更新日期：2013-07-09 00:00:00

abstract：BACKGROUND:Family members of patients with end stage renal disease were reported to have an increased prevalence of chronic kidney disease (CKD). However, studies differentiated genetic and non-genetic family members are limited. We sought to investigate the prevalence of CKD among fist-degree relatives and spouses of ...

journal_title：BMC nephrology

authors： Kong X,Liu L,Zuo L,Yuan P,Li Z,Li W,Cai M,Chen X,Jiang A,Long G,Xu J,Lin H,Wang S,Huang W,Wang Y,Guo Y,Cao P,Wu H,Jia Q,Zhang L,Wang M,Wang H

更新日期：2013-01-18 00:00:00

abstract：BACKGROUND:Chronic kidney disease (CKD) with edema is a common clinical problem resulting from defects in water and solute excretion. Furosemide is the drug of choice for treatment. In theory, good perfusion and albumin are required for the furosemide to be secreted at the tubular lumen. Thus, in the situation of low g...

journal_title：BMC nephrology

authors： Phakdeekitcharoen B,Boonyawat K

更新日期：2012-08-29 00:00:00

abstract：BACKGROUND:Frailty is independently associated with worse health-related quality of life (HRQOL) in chronic kidney disease (CKD). However, the relationship between frailty and symptom experience is not well described in people living with CKD. This study's aim was to evaluate the relationship between frailty and sympto...

journal_title：BMC nephrology

authors： Nixon AC,Wilkinson TJ,Young HML,Taal MW,Pendleton N,Mitra S,Brady ME,Dhaygude AP,Smith AC

更新日期：2020-09-23 00:00:00

abstract：BACKGROUND:Glucocorticoids (GCs) are frequently used to treat glomerular diseases but are associated with multiple adverse effects including hypothalamic-pituitary-adrenal axis inhibition that can lead to adrenal insufficiency (AI) on withdrawal. There is no agreed GC tapering strategy to minimise this risk. METHODS:T...

journal_title：BMC nephrology

authors： Karangizi AHK,Al-Shaghana M,Logan S,Criseno S,Webster R,Boelaert K,Hewins P,Harper L

更新日期：2019-05-06 00:00:00

abstract：BACKGROUND:Liddle's syndrome is a rare monogenic form of hypertension caused by truncating or missense mutations in the C termini of the epithelial sodium channel (ENaC) β or γ subunits. Patients with this syndrome present with early onset of hypertension, hypokalemia, metabolic alkalosis, hyporeninemia and hypoaldoste...

journal_title：BMC nephrology

authors： Yamaguchi E,Yoshikawa K,Nakaya I,Kato K,Miyasato Y,Nakagawa T,Kakizoe Y,Mukoyama M,Soma J

更新日期：2018-05-23 00:00:00

abstract：BACKGROUND:Single nucleotide polymorphisms (SNPs) are the most common forms of sequence variations in the human genome. They contribute to the human phenotypic spectrum and are associated with variations in response to pathogens, drugs and vaccines. Recently, SNPs in three human genes involved in kidney development (RE...

journal_title：BMC nephrology

authors： Raghavendra A,Siji A,Sridhar TS,Phadke K,Vasudevan A

更新日期：2011-10-28 00:00:00

abstract：BACKGROUND:The currently available data with respect to the association between vitamin D receptor (VDR) gene polymorphism and risk to urolithiasis are inconclusive and inconsistent. Hence, an exhaustive meta-analysis can solve the discrepancies and provide a hint for upcoming investigations. Herein, a meta-analysis wa...

journal_title：BMC nephrology

authors： Imani D,Razi B,Khosrojerdi A,Lorian K,Motallebnezhad M,Rezaei R,Aslani S

更新日期：2020-07-10 00:00:00

abstract：BACKGROUND:ANCA-associated vasculitis is a life-threatening, systemic autoimmune disease. There is an increased risk of organ infarction but in many cases this is asymptomatic. We described here the first reported case of PR3 vasculitis presenting with symptomatic bilateral renal wedge infarction. CASE PRESENTATION:A ...

journal_title：BMC nephrology

authors： Bottomley MJ,Gibson M,Alchi B

更新日期：2019-03-06 00:00:00

abstract：BACKGROUND:In a recent study we demonstrated that low birth weight (LBW) was associated with increased risk of progressive IgA nephropathy (IgAN). In the present study we investigate whether this could be explained by differences in glomerular morphological parameters. METHODS:The Medical Birth Registry of Norway has ...

journal_title：BMC nephrology

authors： Ruggajo P,Leh S,Svarstad E,Marti HP,Vikse BE

更新日期：2018-10-22 00:00:00

abstract：BACKGROUND:High water hardness associated with high water fluoride and the geographical distribution of Chronic Kidney Disease of unknown etiology (CKDu) in Sri Lanka are well correlated. We undertook this study to observe the effects of high water hardness with high fluoride on kidney and liver in rats and efficacy of...

journal_title：BMC nephrology

authors： Perera T,Ranasinghe S,Alles N,Waduge R

更新日期：2020-03-24 00:00:00

abstract：BACKGROUND:Ongoing efforts are focused on shortening ischemia intervals as much as possible during partial nephrectomy to preserve renal function. Off-clamp partial nephrectomy (off-PN) has been a common strategy for to avoid ischemia in small renal tumors. Although studies comparing the advantages between off-PN with ...

journal_title：BMC nephrology

authors： Deng W,Liu X,Hu J,Chen L,Fu B

更新日期：2018-07-31 00:00:00

abstract：BACKGROUND:Experimental studies showed that 25-hydroxy-vitamin D [25(OH)D] deficiency (defined as 25-hydroxy-vitamin D < 15 ng/ml) has been associated with CKD progression. Patients with IgA nephropathy have an exceptionally high rate of severe 25(OH)D deficiency; however, it is not known whether this deficiency is a r...

journal_title：BMC nephrology

authors： Li XH,Huang XP,Pan L,Wang CY,Qin J,Nong FW,Luo YZ,Wu Y,Huang YM,Peng X,Yang ZH,Liao YH

更新日期：2016-11-02 00:00:00

abstract：BACKGROUND:Multiple factors influence timing of dialysis initiation. The impact of supply of nephrology workforce on timing and incidence of dialysis initiation is not well known. METHODS:We determined the number of pediatric and adult nephrologists in each state using data from the American Medical Association and Am...

journal_title：BMC nephrology

authors： Ku E,Johansen KL,Portale AA,Grimes B,Hsu CY

更新日期：2015-01-15 00:00:00

abstract：BACKGROUND:Efficient and safe delivery of care to dialysis patients is essential. Concerns have been raised regarding the ability of accountable care organizations to adequately serve this high-risk population. Little is known about primary care involvement in the care of dialysis patients. This study sought to describ...

journal_title：BMC nephrology

authors： Thorsteinsdottir B,Ramar P,Hickson LJ,Reinalda MS,Albright RC,Tilburt JC,Williams AW,Takahashi PY,Jeffery MM,Shah ND

更新日期：2017-10-25 00:00:00

abstract：BACKGROUND:The aim of this study was to describe the findings of renal biopsies from a large nephrology center in Iasi, Romania, performed between 2005 and 2010. We compared these findings with our previous ones, from 1995 to 2004, as well as with similar reports. METHODS:We studied retrospectively 239 renal biopsies....

journal_title：BMC nephrology

authors： Volovăt C,Cãruntu I,Costin C,Stefan A,Popa R,Volovăt S,Siriopol D,Voroneanu L,Nistor I,Segall L,Covic A

更新日期：2013-07-15 00:00:00

abstract：BACKGROUND:Physical inactivity and sedentary behaviour (too much sitting) can contribute to renal dysfunction. However, the potential benefits of behavioural change (e.g. replacing sedentary behaviour with physical activity) on renal function are not well understood. We used isotemporal substitution to model potential ...

journal_title：BMC nephrology

authors： Kosaki K,Tanahashi K,Matsui M,Akazawa N,Osuka Y,Tanaka K,Dunstan DW,Owen N,Shibata A,Oka K,Maeda S

更新日期：2020-06-03 00:00:00

abstract：BACKGROUND:Variants in CUBN, the gene encoding cubilin, a proximal tubular transport protein, have been associated with albuminuria and vitamin B12 (B12) deficiency. We hypothesized that low levels of B12 would be associated with albuminuria in a population-based cohort. METHODS:We analyzed participants from the Frami...

journal_title：BMC nephrology

authors： McMahon GM,Hwang SJ,Tanner RM,Jacques PF,Selhub J,Muntner P,Fox CS

更新日期：2015-02-02 00:00:00

abstract：BACKGROUND:Pyrrolidine dithiocarbamate (PDTC) reduces renal cyst growth in a rodent model of polycystic kidney disease (PKD) but the mechanism of action is not clear. Here, we investigated the hypothesis that PDTC reduces the proliferation of cystic epithelial cells in vitro in a nuclear factor (NF)-κB-dependent manner...

journal_title：BMC nephrology

authors： Ta MH,Liuwantara D,Rangan GK

更新日期：2015-12-15 00:00:00

abstract：:In a recent study published by the National Project Team on chronic kidney diseases of unknown origin in Sri Lanka, identified cadmium as a major risk factor but strong conclusions were not made as the identified environmental toxins were within the permissible levels.Sri Lankan food consumption pattern is different s...

journal_title：BMC nephrology

authors： Jayalal TB

更新日期：2015-12-23 00:00:00

abstract：BACKGROUND:Residing remotely from health care resources appears to impact quality of care delivery. It remains unclear if there are differences in vascular access based on distance of one's residence to dialysis centre at time of dialysis initiation, and whether region or duration of pre-dialysis care are important eff...

journal_title：BMC nephrology

authors： Miller LM,Vercaigne LM,Moist L,Lok CE,Tangri N,Komenda P,Rigatto C,Mojica J,Sood MM

更新日期：2014-02-27 00:00:00

abstract：BACKGROUND:Polycystic Kidney Disease (PKD) kidneys exhibit increased extracellular matrix (ECM) collagen expression and metalloproteinases (MMPs) activity. We investigated the role of these increases on cystic disease progression in PKD kidneys. METHODS:We examined the role of type I collagen (collagen I) and membrane...

journal_title：BMC nephrology

authors： Liu B,Li C,Liu Z,Dai Z,Tao Y

更新日期：2012-09-11 00:00:00

abstract：INTRODUCTION:Urinary biomarkers of kidney injury are presumed to reflect renal tubular damage. However, their concentrations may be influenced by other factors, such as hematuria or pyuria. We sought to examine what non-injury related urinalysis factors are associated with urinary biomarker levels. METHODS:We examined...

journal_title：BMC nephrology

authors： Nadkarni GN,Coca SG,Meisner A,Patel S,Kerr KF,Patel UD,Koyner JL,Garg AX,Philbrook HT,Edelstein CL,Shlipak M,El-Khoury J,Parikh CR,TRIBE-AKI Consortium Investigators.

更新日期：2017-07-06 00:00:00

abstract：BACKGROUND:Nephrotic syndrome (NS) is pathological condition characterized by heavy proteinuria. Our study investigates hypothesis that change in cell proliferation of proximal tubules influences primary cilia structure and function and promotes cystogenesis in congenital nephrotic syndrome of the Finnish type (CNF) an...

journal_title：BMC nephrology

authors： Saraga M,Vukojević K,Krželj V,Puretić Z,Bočina I,Durdov MG,Weber S,Dworniczak B,Ljubanović DG,Saraga-Babić M

更新日期：2014-01-08 00:00:00

abstract：BACKGROUND:Evidence suggests that alkaline phosphatase attenuates inflammatory response in sepsis by lipopolysaccharide detoxification and adenosine triphosphate dephosphorylation. We sought to determine changes in alkaline phosphatase (AP) activity during septic acute kidney injury (AKI) and clinical parameters associ...

journal_title：BMC nephrology

authors： Baek SD,Kang JY,Yu H,Shin S,Park HS,Kim MS,Lee EK,Kim SM,Chang JW

更新日期：2018-09-20 00:00:00

abstract：BACKGROUND:Patients with pre-existing impaired renal function are prone to develop acute contrast media induced nephropathy (CIN). Neutrophil gelatinase-associated lipocalin (NGAL), a new biomarker predictive for acute kidney injury (AKI), has been shown to be useful for earlier diagnosis of CIN; however, urinary NGAL ...

journal_title：BMC nephrology

authors： Schilcher G,Ribitsch W,Otto R,Portugaller RH,Quehenberger F,Truschnig-Wilders M,Zweiker R,Stiegler P,Brodmann M,Weinhandl K,Horina JH

更新日期：2011-08-17 00:00:00

abstract：BACKGROUND:The purpose of this study was to evaluate the feasibility of utilizing an in-vitro, closed loop hemodialysis system as a method to assess drug clearance. Secondarily, this study tested the influence of variables (blood flow rate, dialysate flow rate, and type of filter) in the hemodialysis procedure on the c...

journal_title：BMC nephrology

authors： Jang SM,Cardone KE,Nolin TD,Mason DL,Grabe DW

更新日期：2014-12-20 00:00:00

abstract：BACKGROUND:Gitelman syndrome (GS) is an autosomal recessive inherited salt-losing tubulopathy (SLT). Here, we describe, for the first time, a case of GS without Gitelman-like features and with concomitant kidney stones, cysts and diabetic nephropathy (DN). CASE PRESENTATION:We described a male patient had a 19-year hi...

journal_title：BMC nephrology

authors： Chen Q,Wang X,Min J,Wang L,Mou L

更新日期：2021-01-07 00:00:00

abstract：BACKGROUND:Rituximab is widely used in kidney transplantation. However, it is not clear whether the conventional doses of maintenance immunosuppressant in rituximab-treated kidney transplantation (KT) are appropriate. In our previous study, decreasing mycophenolate mofetil (MMF) dose due to infection did not increase t...

journal_title：BMC nephrology

authors： Baek CH,Kim H,Yu H,Shin E,Cho H,Yang WS,Han DJ,Park SK

更新日期：2015-12-04 00:00:00

abstract：BACKGROUND:Patients with chronic kidney diseases (CKD) on haemodialysis (HD) have high morbidity and mortality rates, which are also due to the inherent risks associated with nephropathy. Non-adherence (NA) to the different demands of the treatment can have consequences for the outcome of patients undergoing HD; nevert...

journal_title：BMC nephrology

authors： Dantas LGG,de Seixas Rocha M,Junior JAM,Paschoalin EL,Paschoalin SRKP,Sampaio Cruz CM

更新日期：2019-11-06 00:00:00