Abstract:
:Due to the functional properties and physiological effects often associated with chemically modified starches, significant interest lies in their development for incorporation in processed foods. This study investigated the effect of transglycosylated cornstarch (TGS) on blood glucose, insulin, and serum metabolome in the pre- and postprandial phase in growing pigs. Eight jugular vein-catheterized barrows were fed two diets containing 72% purified starch (waxy cornstarch (CON) or TGS). A meal tolerance test (MTT) was performed with serial blood sampling for glucose, insulin, lipids, and metabolome profiling. TGS-fed pigs had reduced postprandial insulin (p < 0.05) and glucose (p < 0.10) peaks compared to CON-fed pigs. The MTT showed increased (p < 0.05) serum urea with TGS-fed pigs compared to CON, indicative of increased protein catabolism. Metabolome profiling showed reduced (p < 0.05) amino acids such as alanine and glutamine with TGS, suggesting increased gluconeogenesis compared to CON, probably due to a reduction in available glucose. Of all metabolites affected by dietary treatment, alkyl-acyl-phosphatidylcholines and sphingomyelins were generally increased (p < 0.05) preprandially, whereas diacyl-phosphatidylcholines and lysophosphatidylcholines were decreased (p < 0.05) postprandially in TGS-fed pigs compared to CON. In conclusion, TGS led to changes in postprandial insulin and glucose metabolism, which may have caused the alterations in serum amino acid and phospholipid metabolome profiles.
journal_name
Nutrientsjournal_title
Nutrientsauthors
Newman MA,Zebeli Q,Eberspächer E,Grüll D,Molnar T,Metzler-Zebeli BUdoi
10.3390/nu9030291subject
Has Abstractpub_date
2017-03-16 00:00:00issue
3issn
2072-6643pii
nu9030291journal_volume
9pub_type
杂志文章相关文献
Nutrients文献大全abstract::The COVID-19 pandemic has disrupted many aspects of daily life. The purpose of this study was to identify how health behaviors, level of stress, financial and food security have been impacted by the pandemic among Canadian families with young children. Parents (mothers, n = 235 and fathers, n = 126) from 254 families ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12082352
更新日期:2020-08-07 00:00:00
abstract::This review discusses the personalised dietary approach with respect to inflammatory bowel disease (IBD). It identifies gene-nutrient interactions associated with the nutritional deficiencies that people with IBD commonly experience, and the role of the Western diet in influencing these. It also discusses food intoler...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu11071532
更新日期:2019-07-05 00:00:00
abstract::Previous psychological studies have shown that images of food elicit hedonic responses, either consciously or unconsciously, and that participants' cultural experiences moderate conscious hedonic ratings of food. However, whether cultural factors moderate unconscious hedonic responses to food remains unknown. We inves...
journal_title:Nutrients
pub_type: 杂志文章,多中心研究
doi:10.3390/nu11112832
更新日期:2019-11-19 00:00:00
abstract::This cross-sectional study investigates whether calcium intakes from dairy and non-dairy sources, and absolute intakes of various dairy products, are associated with periodontitis. The calcium intake (mg/day) of 135 older Danish adults was estimated by a diet history interview and divided into dairy and non-dairy calc...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu4091219
更新日期:2012-09-01 00:00:00
abstract::Chicken extract, which is rich in anserine and carnosine, has been widely taken in Asian countries as a traditional remedy with various aims, including attenuation of psychological fatigue. The effects of consuming BRAND'S Essence of Chicken (EOC) or a placebo on 46 young adults' responses to a standard psychological ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu7020887
更新日期:2015-01-29 00:00:00
abstract::The gluten-free diet is effective in the majority of celiac disease (CD) patients, but it is burdensome and may influence quality of life (QoL). The aim of the study was to analyze the social and emotional fears and worries influencing the QoL of female CD patients following a gluten-free (GF) diet, as well as to indi...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu10101414
更新日期:2018-10-03 00:00:00
abstract::Chronic kidney disease and reduced glomerular filtration rate are risk factors for the development of chronic metabolic acidosis. The prevention or correction of chronic metabolic acidosis has been found to slow progression of chronic kidney disease. Dietary composition can strongly affect acid⁻base balance. Major det...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu10040512
更新日期:2018-04-20 00:00:00
abstract::Resting metabolic rate (RMR) declines with aging and is related to changes in health status, but how specific health impairments impact basal metabolism over time has been largely unexplored. We analyzed the association of RMR with 15 common age-related chronic diseases for up to 13 years of follow-up in a population ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12103061
更新日期:2020-10-07 00:00:00
abstract::Ocoxin Oral Solution (OOS) is a nutritional supplement whose formulation includes several plant extracts and natural products with demonstrated antitumoral properties. This review summarizes the antitumoral action of the different constituents of OOS. The action of this formulation on different preclinical models as w...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu12092661
更新日期:2020-08-31 00:00:00
abstract::Obesity has recently risen and become a serious health concern in Korea according to the westernized diet and altered lifestyle. Hence, there is a growing interest in the supplementation of phytochemicals to find a safe and effective functional ingredient to treat obesity. Spergularia marina Griseb (SM) has traditiona...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12020336
更新日期:2020-01-27 00:00:00
abstract::The rapidly increasing prevalence of overweight and obesity demands new strategies focusing on prevention and treatment of this significant health care problem. In the search for new and effective therapeutic modalities for overweight subjects, the gastrointestinal (GI) tract is increasingly considered as an attractiv...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu8030117
更新日期:2016-02-26 00:00:00
abstract::The rating of perceived exertion (RPE) indicates the feeling of fatigue. However, hypoxia worsens the condition and can worsen RPE. We evaluated whether carbohydrate and glutamine supplementation alters RPE and physiological markers in running at 70% peak oxygen uptake until exhaustion in a simulated altitude of 4500 ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12123797
更新日期:2020-12-11 00:00:00
abstract::Curcumin, a nontoxic, naturally occurring polyphenol, has been recently proposed for the management of neurodegenerative and neurological diseases. However, a discrepancy exists between the well-documented pharmacological activities that curcumin seems to possess in vivo and its poor aqueous solubility, bioavailabilit...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu11102426
更新日期:2019-10-11 00:00:00
abstract::Chronic joint inflammatory disorders such as osteoarthritis and rheumatoid arthritis have in common an upsurge of inflammation, and oxidative stress, resulting in progressive histological alterations and disabling symptoms. Currently used conventional medication (ranging from pain-killers to biological agents) is pote...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu9010070
更新日期:2017-01-16 00:00:00
abstract::Metabolomics provide an unbiased tool for exploring the modulation of the human metabolome in response to food intake. This study applied metabolomics to capture the postprandial metabolic response to breakfast meals corresponding to vegan (VE), lacto ovo-vegetarian (LOV), and omnivore (OM) diets. In a cross over desi...
journal_title:Nutrients
pub_type: 杂志文章,随机对照试验
doi:10.3390/nu10081063
更新日期:2018-08-10 00:00:00
abstract::Animal studies using tests and models have demonstrated that magnesium exerts an antidepressant effect. The literature contains few studies in humans involving attempts to augment antidepressant therapy with magnesium ions. The purpose of our study was to assess the efficacy and safety of antidepressant treatment, in ...
journal_title:Nutrients
pub_type: 杂志文章,随机对照试验
doi:10.3390/nu10081014
更新日期:2018-08-03 00:00:00
abstract::High sugar intake in childhood has been linked to obesity. However, the role of macronutrient substitutions and associations with metabolic health remain unclear. We examined associations of carbohydrate intake and its subtypes with body composition and metabolic health among 3573 children participating in a populatio...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12071940
更新日期:2020-06-30 00:00:00
abstract:BACKGROUND:Numerous scientific studies on patients with autism spectrum disorder (ASD) suggest a significant role of inflammation processes or lipid disorders in this spectrum of neurodevelopmental disorders. Unfortunately, there is a lack of assessments of changes over time regarding level of lipids and inflammatory m...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12092594
更新日期:2020-08-26 00:00:00
abstract::Children born from mothers with gestational diabetes mellitus (GDM) are at high-risk of obesity and type 2 diabetes. To date, there is a lack of effective strategies to prevent these complications. The aim of this study was to evaluate the association between diet quality and anthropometric and glycemic profiles of ch...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11030570
更新日期:2019-03-07 00:00:00
abstract::This study aimed to evaluate dietary nutrient intake among Chinese pregnant women by comparison with Chinese Dietary Reference Intakes (DRIs) and to explore the association between dietary nutrients and preterm birth. A case-control design was conducted in Beijing with 130 preterm delivery mothers in case group and 38...
journal_title:Nutrients
pub_type: 杂志文章,多中心研究
doi:10.3390/nu9030221
更新日期:2017-03-01 00:00:00
abstract::Reducing salt intake is a cost-effective public health intervention to reduce the global burden of non-communicable disease (NCDs). Ultra-processed foods contribute ~80% of dietary salt in high income countries, and are becoming prominent in low-middle income countries. Instant noodle consumption is particularly high ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu9060612
更新日期:2017-06-16 00:00:00
abstract::Human milk oligosaccharides (HMOs) are multifunctional carbohydrates naturally present in human milk that act as prebiotics, prevent pathogen binding and infections, modulate the immune system and may support brain development in infants. HMOs composition is very individualized and differences in HMOs concentrations m...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11061358
更新日期:2019-06-17 00:00:00
abstract::Spinal muscular atrophy (SMA), the main genetic cause of infant death, is a neurodegenerative disease characterized by the selective loss of motor neurons in the anterior horn of the spinal cord, accompanied by muscle wasting. Pathomechanically, SMA is caused by low levels of the survival motor neuron protein (SMN) re...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu12123842
更新日期:2020-12-16 00:00:00
abstract::Berries are considered "promising functional fruits" due to their distinct and ubiquitous therapeutic contents of anthocyanins, proanthocyanidins, phenolic acids, flavonoids, flavanols, alkaloids, polysaccharides, hydroxycinnamic, ellagic acid derivatives, and organic acids. These polyphenols are part of berries and t...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu12092538
更新日期:2020-08-21 00:00:00
abstract::Confusion has persisted for decades in the United States (U.S.) over how much plain water to drink, despite national water intake recommendations which are based on high quality scientific evidence. This editorial summarizes the definition, alignment and coordination of evidence that informs the current U.S. adequate ...
journal_title:Nutrients
pub_type: 社论
doi:10.3390/nu12113359
更新日期:2020-10-31 00:00:00
abstract::Flavonoids are a class of polyphenolic compounds that naturally occur in plants. Sub-groups of flavonoids include flavone, flavonol, flavanone, flavanonol, anthocyanidin, flavanol and isoflavone. The various modifications on flavonoid molecules further increase the diversity of flavonoids. Certain crops are famous for...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu12061717
更新日期:2020-06-08 00:00:00
abstract::Aging is a complex phenomenon characterized by the progressive loss of tissue and organ function. The oxidative-stress theory of aging postulates that age-associated functional losses are due to the accumulation of ROS-induced damage. Liver function impairment and non-alcoholic fatty liver disease (NAFLD) are common a...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11040872
更新日期:2019-04-18 00:00:00
abstract::The association of high vitamin A intake and low bone mineral density (BMD) is still controversial. To determine the association of dietary vitamin A intake and serum 25-hydroxyvitamin D (25(OH)D) concentration with BMD, a total of 6481 subjects (2907 men and 3574 women) aged ≥50 years from the Korean National Health ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu7031716
更新日期:2015-03-10 00:00:00
abstract::Vegetarian diets provide an abundance of nutrients when carefully planned. However, vegetarian diets may have lower protein quality compared to omnivorous diets, a reflection of less favorable amino acid profiles and bioavailability. Hence, the current recommended dietary allowance for protein may not be adequate for ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11123016
更新日期:2019-12-10 00:00:00
abstract::Kynurenic acid, a metabolite of the kynurenine pathway of tryptophan catabolism, acts as an antagonist for both the α7 nicotinic acetylcholine receptor and glycine coagonist sites of the N-methyl-d-aspartic acid receptor at endogenous brain concentrations. Elevation of brain kynurenic acid levels reduces the release o...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu12051403
更新日期:2020-05-13 00:00:00