Abstract:
:Animal studies using tests and models have demonstrated that magnesium exerts an antidepressant effect. The literature contains few studies in humans involving attempts to augment antidepressant therapy with magnesium ions. The purpose of our study was to assess the efficacy and safety of antidepressant treatment, in combination with magnesium ions. A total of 37 participants with recurrent depressive disorder who developed a depressive episode were included in this study. As part of this double-blind study, treatment with the antidepressant fluoxetine was accompanied with either magnesium ions (120 mg/day as magnesium aspartate) or placebo. During an 8-week treatment period, each patient was monitored for any clinical abnormalities. Moreover, serum fluoxetine and magnesium levels were measured, and pharmaco-electroencephalography was performed. The fluoxetine + magnesium and fluoxetine + placebo groups showed no significant differences in either Hamilton Depression Rating Scale (HDRS) scores or serum magnesium levels at any stage of treatment. Multivariate statistical analysis of the whole investigated group showed that the following parameters increased the odds of effective treatment: lower baseline HDRS scores, female gender, smoking, and treatment augmentation with magnesium. The parameters that increased the odds of remission were lower baseline HDRS scores, shorter history of disease, the presence of antidepressant-induced changes in the pharmaco-EEG profile at 6 h after treatment, and the fact of receiving treatment augmented with magnesium ions. The limitation of this study is a small sample size.
journal_name
Nutrientsjournal_title
Nutrientsauthors
Ryszewska-Pokraśniewicz B,Mach A,Skalski M,Januszko P,Wawrzyniak ZM,Poleszak E,Nowak G,Pilc A,Radziwoń-Zaleska Mdoi
10.3390/nu10081014subject
Has Abstractpub_date
2018-08-03 00:00:00issue
8issn
2072-6643pii
nu10081014journal_volume
10pub_type
杂志文章,随机对照试验相关文献
Nutrients文献大全abstract::Even though irritable bowel syndrome (IBS) has been known for more than 150 years, it still remains one of the research challenges of the 21st century. According to the current diagnostic Rome IV criteria, IBS is characterized by abdominal pain associated with defecation and/or a change in bowel habit, in the absence ...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu11092162
更新日期:2019-09-09 00:00:00
abstract::In their study, Adams et al. [1] attempted to determine whether thirst perception could serve as a reliable marker of hydration status during 3 h of exercise where participants either dehydrated by 3% of their body mass or maintained euhydration through water intake, and following exercise where they either could not ...
journal_title:Nutrients
pub_type: 评论,杂志文章
doi:10.3390/nu12010215
更新日期:2020-01-14 00:00:00
abstract::Restricting animal-based products from diet may exert beneficial effects on weight status; however, less is known about such a diet and emotional health. Moreover, personality traits, for example high neuroticism, may contribute to restrictive eating habits and potentially confound diet-health associations. We aim to ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12051492
更新日期:2020-05-20 00:00:00
abstract::Although vitamin B6 is contained in various foods, its deficiency is one of the most common micronutrient deficiencies worldwide. Furthermore, patients with obesity and cardiovascular disease are more likely to have suboptimal vitamin B6 status than healthy people. Therefore, we investigated the effects of dietary vit...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12123821
更新日期:2020-12-14 00:00:00
abstract::Human milk is the optimal food for human infants, including infants born prematurely. In the event that a mother of a hospitalized infant cannot provide breast milk, donor milk is considered an acceptable alternative. It is known that the macronutrient composition of donor milk is different than human milk, with varia...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu8110681
更新日期:2016-10-28 00:00:00
abstract::Obesity and weight gain in bipolar disorder (BD) have multifactorial underlying causes such as medication side effects, atypical depressive symptomatology, genetic variants, and disturbances in the neuro-endocrinal system. Therefore, we aim to explore the associations between food craving (FC), clinical parameters, ps...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu13010076
更新日期:2020-12-29 00:00:00
abstract::Parents' stress is independently associated with increased child adiposity, but parents' stress may also interfere with childhood obesity prevention programs. The disruptions to the family dynamic caused by participating in a behaviour change intervention may exacerbate parent stress and undermine overall intervention...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12061835
更新日期:2020-06-19 00:00:00
abstract::The objective of this cross-sectional study was to evaluate the relationship between micronutrient status and obesity, lipids, insulin resistance and chronic inflammation in children. Weight, height, waist circumference and body composition (dual-energy X-ray absorptiometry (DEXA)) were determined in 197 school-aged c...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu5125012
更新日期:2013-12-10 00:00:00
abstract::The etiopathogenesis of Inflammatory bowel disease (IBD) is a result of a complex interaction between host immune response, the gut microbiome and environmental factors, such as diet. Although scientific advances, with the use of biological medications, have revolutionized IBD treatment, the challenge for maintaining ...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu12072018
更新日期:2020-07-07 00:00:00
abstract::New Zealand has one of the highest rates of Crohn's Disease (CD) in the world, and there is much speculation as to why this might be. A high risk of CD has been associated with deficient or insufficient levels of Vitamin D (Vit D), lifestyle as well as various genetic polymorphisms. In this study we sought to analyse ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu5103898
更新日期:2013-09-27 00:00:00
abstract::High sugar intake in childhood has been linked to obesity. However, the role of macronutrient substitutions and associations with metabolic health remain unclear. We examined associations of carbohydrate intake and its subtypes with body composition and metabolic health among 3573 children participating in a populatio...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12071940
更新日期:2020-06-30 00:00:00
abstract::Bacterial vaginosis and vulvovaginal candidiasis are common causes of impaired health and quality of life for women. Although antimicrobial agents remain the main strategy for the treatment of vaginal infections, their repeated use involves high rates of resistance and recurrence. Alternative approaches such as probio...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12082211
更新日期:2020-07-24 00:00:00
abstract::The circadian rhythm of urinary sodium excretion is related to the diurnal blood pressure regulation (BP) and the nocturnal dipping pattern. The renal sodium excretion expressed as daytime/nighttime ratio impacts BP, but a limited number of studies have investigated this topic to date. In this cross-sectional study, w...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12072013
更新日期:2020-07-07 00:00:00
abstract::This study sought to describe and compare adherence to the Mediterranean diet and consumption of local foods from the Huelva region among Spanish university women in relation to menstrual pain and other menstrual characteristics. This cross-sectional study included 311 health science students. The study variables were...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12061759
更新日期:2020-06-12 00:00:00
abstract:BACKGROUND:Hereditary fructose intolerance (HFI) is a rare genetic disorder of fructose metabolism due to aldolase B enzyme deficiency. Treatment consists of fructose, sorbitol, and sucrose (FSS)-free diet. We explore possible correlations between daily fructose traces intake and liver injury biomarkers on a long-term ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11102397
更新日期:2019-10-07 00:00:00
abstract::The motivation to seek and consume water is an essential component of human fluid-electrolyte homeostasis, optimal function, and health. This review describes the evolution of concepts regarding thirst and drinking behavior, made possible by magnetic resonance imaging, animal models, and novel laboratory techniques. T...
journal_title:Nutrients
pub_type: 历史文章,杂志文章,评审
doi:10.3390/nu11122864
更新日期:2019-11-22 00:00:00
abstract::The accumulation of free radicals and advanced glycation end products (AGEs) in the skin plays a very important role in skin aging. Both are known to interact with each other. Therefore, natural compounds or extracts that possess both antioxidant and antiglycation activities might have great antiageing potential. Akeb...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu7115478
更新日期:2015-11-12 00:00:00
abstract::Decreased renal function, elevated circulating levels of urea, intestinal levels of urea-degrading bacteria, and gut-derived uremic metabolites are present in end-stage renal disease (ESRD), a cohort that has reduced muscle mass and physical function, and poor muscle composition. This phenotype, defined as the kidney-...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12010106
更新日期:2019-12-30 00:00:00
abstract::Women experience physical, mental, and social changes during menopause. It is important to maintain a healthy diet for effective menopause management. The effect of germinated Superjami, a deep violet colored rice cultivar, on the body weight, glucose level, antioxidant defense system, and bone metabolism in a menopau...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11092184
更新日期:2019-09-11 00:00:00
abstract::NutritionDay (nDay) is a project established by the Medical University of Vienna and the European Society for Clinical Nutrition and Metabolism (ESPEN) to audit the nutritional status of hospitalized patients and nursing home residents. This study aimed to evaluate nDay data describing the prevalence of hospital malnu...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu13010263
更新日期:2021-01-18 00:00:00
abstract::The present study investigated the effects of breast tumors on the blood and tissue distribution of essential trace mineral selenium (Se), and oxidative stress status of mice. Female 10-week-old BALB/cByJNarl mice were randomly assigned into control (CNL) and breast tumor-bearing (TB) groups. TB mice were injected sub...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu5020594
更新日期:2013-02-20 00:00:00
abstract::In adults, fermentation of high amylose maize starch (HAMS), a resistant starch (RS), has a prebiotic effect. Were such a capacity to exist in infants, intake of RS might programme the gut microbiota during a critical developmental period. This study aimed to determine if infant faecal inocula possess the capacity to ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11061345
更新日期:2019-06-14 00:00:00
abstract::Carotenoids can be metabolized to various apo-carotenoids and retinoids. Apo-15´-carotenoic acid (retinoic acid, RA) is a potent activator of the retinoic acid receptor (RAR) in its all-trans- (ATRA) and 9-cis- (9CRA) forms. In this study we show firstly, that apo-14´-carotenoic acid (A14CA), besides retinoic acids, i...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11092084
更新日期:2019-09-04 00:00:00
abstract::Many of the health benefits associated with dietary fiber are attributed to their fermentation by microbiota and production of short chain fatty acids (SCFA). The aim of this study was to investigate the fermentability of the functional fiber PolyGlyopleX® (PGX®) in vitro. A validated dynamic, computer-controlled in v...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu6031115
更新日期:2014-03-14 00:00:00
abstract::Today's industrial food production contributes significantly to environmental degradation. Meat production accounts for the largest impact, including greenhouse gas emissions, land and water use. While food production and consumption are important aspects when addressing climate change, this article focuses predominan...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu9040412
更新日期:2017-04-21 00:00:00
abstract::Globally, colorectal cancer (CRC) is the third most common form of cancer. The development of effective chemopreventive strategies to reduce CRC incidence is therefore of paramount importance. Over the past decade, research has indicated the potential of rice bran, a byproduct of rice milling, in CRC chemoprevention. ...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu8090569
更新日期:2016-09-15 00:00:00
abstract::Iron deficiency is the most common micronutrient deficiency in the world. Women of reproductive age and young children are particularly vulnerable. Iron deficiency in late prenatal and early postnatal periods can lead to long-term neurobehavioral deficits, despite iron treatment. This may occur because screening and t...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu10020227
更新日期:2018-02-17 00:00:00
abstract::Tocotrienols have been reported to improve lipid profiles, reduce atherosclerotic lesions, decrease blood glucose and glycated haemoglobin concentrations, normalise blood pressure in vivo and inhibit adipogenesis in vitro, yet their role in the metabolic syndrome has not been investigated. In this study, we investigat...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu4101527
更新日期:2012-10-22 00:00:00
abstract::Increases in the number of food outlets have been proposed as a key factor driving obesity. This study aimed to investigate the association between the densities of food establishments serving meals (excluding supermarkets and grocery stores), with body mass index (BMI), waist to hip ratio (WHR) and percentage of body...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12040890
更新日期:2020-03-25 00:00:00
abstract::Hydroxycinnamic acids (HCAs) are important natural phenolic compounds present in high concentrations in fruits, vegetables, cereals, coffee, tea and wine. Many health beneficial effects have been acknowledged in food products rich in HCAs; however, food processing, dietary intake, bioaccessibility and pharmacokinetics...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu12082190
更新日期:2020-07-23 00:00:00