Abstract:
:Globally, colorectal cancer (CRC) is the third most common form of cancer. The development of effective chemopreventive strategies to reduce CRC incidence is therefore of paramount importance. Over the past decade, research has indicated the potential of rice bran, a byproduct of rice milling, in CRC chemoprevention. This was recently suggested to be partly attributable to modification in the composition of intestinal microbiota when rice bran was ingested. Indeed, previous studies have reported changes in the population size of certain bacterial species, or microbial dysbiosis, in the intestines of CRC patients and animal models. Rice bran intake was shown to reverse such changes through the manipulation of the population of health-promoting bacteria in the intestine. The present review first provides an overview of evidence on the link between microbial dysbiosis and CRC carcinogenesis and describes the molecular events associated with that link. Thereafter, there is a summary of current data on the effect of rice bran intake on the composition of intestinal microbiota in human and animal models. The article also highlights the need for further studies on the inter-relationship between rice bran intake, the composition of intestinal microbiota and CRC prevention.
journal_name
Nutrientsjournal_title
Nutrientsauthors
So WK,Law BM,Law PT,Chan CW,Chair SYdoi
10.3390/nu8090569subject
Has Abstractpub_date
2016-09-15 00:00:00issue
9issn
2072-6643pii
nu8090569journal_volume
8pub_type
杂志文章,评审相关文献
Nutrients文献大全abstract::Both vitamin D deficiency and cognitive impairment are common in patients with chronic kidney disease (CKD). Vitamin D exerts neuroprotective and regulatory roles in the central nervous system. Hypovitaminosis D has been associated with muscle weakness and bone loss, cardiovascular diseases (hypertension, diabetes and...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu8050291
更新日期:2016-05-13 00:00:00
abstract:OBJECTIVE:To investigate dietary habits, sleep and psychological well-being of adolescents and medical students during COVID-19 lockdown in Split, Croatia. METHODS:We surveyed 1326 students during 2018 and 2019, and compared their responses with 531 students enrolled in May 2020. Perceived stress, quality of life (QoL...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu13010097
更新日期:2020-12-30 00:00:00
abstract::The first manifestations that appear under zinc deficiency are skin defects such as dermatitis, alopecia, acne, eczema, dry, and scaling skin. Several genetic disorders including acrodermatitis enteropathica (also known as Danbolt-Closs syndrome) and Brandt's syndrome are highly related to zinc deficiency. However, th...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu10020219
更新日期:2018-02-16 00:00:00
abstract::Peptides from fish may beneficially affect several metabolic outcomes, including gut health and inflammation. The effect of fish peptides in subjects with irritable bowel syndrome (IBS) has not previously been investigated, hence this study aimed to evaluate the effect of a cod protein hydrolysate (CPH) supplement on ...
journal_title:Nutrients
pub_type: 杂志文章,随机对照试验
doi:10.3390/nu11071635
更新日期:2019-07-17 00:00:00
abstract::The major part of iron present in plant foods such as cereals is largely unavailable for direct absorption in humans due to complexation with the negatively charged phosphate groups of phytate (myo-inositol (1,2,3,4,5,6)-hexakisphosphate). Human biology has not evolved an efficient mechanism to naturally release iron ...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu5083074
更新日期:2013-08-02 00:00:00
abstract::Recent studies have emphasized the role of the maternal diet in the development of mental disorders in offspring. Substance use disorder is a major global health and economic burden. Therefore, the search for predisposing factors for the development of this disease can contribute to reducing the health and social dama...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12051462
更新日期:2020-05-19 00:00:00
abstract::A low Omega-3 Index (eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in erythrocytes) is associated with cardiac, cerebral, and other health issues. Intake of EPA and DHA, but not of alpha-linolenic acid (ALA), increases the Omega-3 Index. We investigated bioavailability, safety, palatability and tolerabili...
journal_title:Nutrients
pub_type: 杂志文章,随机对照试验
doi:10.3390/nu9060629
更新日期:2017-06-19 00:00:00
abstract::Oligosaccharides (OS) are commonly added to infant formulas, however, their physiological impact, particularly on adult health programming, is poorly described. In adult animals, OS modify microbiota and stimulate colonic fermentation and enteroendocrine cell (EEC) activity. Since neonatal changes in microbiota and/or...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11091967
更新日期:2019-08-21 00:00:00
abstract::Understanding the regulation of gene activities depending on DNA methylation has been the subject of much recent study. However, although polymorphisms of the HTR2A gene have been associated with both obesity and psychiatric disorders, the role of HTR2A gene methylation in these illnesses remains uncertain. The aim of...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu6062387
更新日期:2014-06-23 00:00:00
abstract::The role of vitamin D in obesity appears to be linked to vitamin D insufficient/deficient status. However, mechanistic understanding of the role of vitamin D in obesity is lacking. We have shown earlier that the vitamin D hormonal form, 1,25-dihydroxyvitamin D3 (1,25(OH)2D3), induces cell death by apoptosis in mature ...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu12051392
更新日期:2020-05-13 00:00:00
abstract:BACKGROUND:Zinc is an essential nutrient for all forms of life and its deficiency affects the normal growth and development of human beings. OBJECTIVE:The main aim was to investigate zinc nutritional status by serum zinc concentration (SZC) and dietary zinc intake and their association in cystic fibrosis (CF) patients...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11010150
更新日期:2019-01-11 00:00:00
abstract::Historically, Mangifera indica L. cultivations have been widely planted in tropical areas of India, Africa, Asia, and Central America. However, at least 20 years ago its spreading allowed the development of some cultivars in Sicily, an island to the south of Italy, where the favourable subtropical climate and adapted ...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu9050525
更新日期:2017-05-20 00:00:00
abstract::Animal experimentation has a long history in the study of metabolic syndrome-related disorders. However, no consensus exists on the best models to study these syndromes. Knowing that different diets can precipitate different metabolic disease phenotypes, herein we characterized several hypercaloric rat models of obesi...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11061197
更新日期:2019-05-28 00:00:00
abstract:BACKGROUND:Vitamin D and calcium are important dietary compounds that affect bone mass, even if other minerals (potassium, zinc, etc.) and vitamins (A, C and K) are also involved. Vitamin D and certain minerals, in fact, play an important role in calcium homeostasis and calcium absorption. Hip fracture incidence is hig...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu12061743
更新日期:2020-06-10 00:00:00
abstract::In this study, we aimed to examine the effect of vitamin D deficiency on all-cause mortality in ankylosing spondylitis (AS) patients and in the general population. This is a retrospective-cohort study based on the electronic database of the largest health-maintenance organization in Israel. AS patients who were first ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12051400
更新日期:2020-05-13 00:00:00
abstract::The ketogenic diet (KD), a high-lipid and low-carbohydrate diet, has been used in the treatment of epilepsy, neurodegenerative disorders, inborn errors of metabolism and cancer; however, the exact mechanism/s of its therapeutic effect is not completely known. We hypothesized that sirtuins (SIRT)-a group of seven NAD-d...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12082379
更新日期:2020-08-08 00:00:00
abstract:BACKGROUND:The microbiota composition is now considered as one of the main modifiable risk factors for health. No controlled study has been performed on the association between microbiota composition and renal function. We applied Mendelian randomization (MR) to estimate the casual impact of eight microbiota genera on ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12082216
更新日期:2020-07-25 00:00:00
abstract::This paper examines fruit and vegetable intake (FVI) in low-income households that participated in a cost-offset (CO), or 50% subsidized, community-supported agriculture (CSA) program. CSA customers paid farms upfront for a share of the harvest, and received produce weekly throughout the growing season. A cohort of ad...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu9070726
更新日期:2017-07-08 00:00:00
abstract::Cherries are known for their nutraceutical properties, in particular for their antioxidant ability due to their polyphenol content, which causes a reduction of cardiovascular disease (CVD) risk factors. However, once ingested these molecules are degraded in the Gastrointestinal (GI) tract before reaching the blood, wh...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu10111598
更新日期:2018-11-01 00:00:00
abstract::Milk fat is encased in a polar lipid-containing tri-layer milk fat globule membrane (MFGM), composed of phospholipids (PLs) and sphingolipids (SLs). Milk PLs and SLs comprise about 1% of total milk lipids. The surfactant properties of PLs are important for dairy products; however, dairy products vary considerably in t...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu12041001
更新日期:2020-04-04 00:00:00
abstract::Osteoporosis and associated low energy fractures are a significant clinical problem, especially in the elderly population. The occurrence of a hip fracture is associated with significant mortality and a high risk of disability. For this, apart from the treatment of osteoporosis, effective prevention of both the develo...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu12082394
更新日期:2020-08-10 00:00:00
abstract::This is the first study to evaluate vitamin K status in relation to dietary intake and phenylalanine dietary compliance in patients with phenylketonuria (PKU). The dietary and PKU formula intake of vitamin K was calculated in 34 PKU patients, with vitamin K status determined by the measurement of prothrombin induced b...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12061772
更新日期:2020-06-14 00:00:00
abstract::Succinate is a metabolic intermediate of the tricarboxylic acid (TCA) cycle within host cells. Succinate is also produced in large amounts during bacterial fermentation of dietary fiber. Elevated succinate levels within the gut lumen have been reported in association with microbiome disturbances (dysbiosis), as well a...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu11010025
更新日期:2018-12-22 00:00:00
abstract::Although a number of studies explain the association between dietary patterns, which take into account that foods are eaten in combination, and breast cancer risk, the findings are inconsistent. We examined the association between dietary patterns and multi-grain rice intake, and the risk of breast cancer in a large-s...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12082273
更新日期:2020-07-29 00:00:00
abstract::The intestinal microbiome plays an important role in maintaining health throughout life. The microbiota develops progressively after birth and is influenced by many factors, including the mode of delivery, antibiotics, and diet. Maternal milk is critically important to the development of the neonatal intestinal microb...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu12030823
更新日期:2020-03-20 00:00:00
abstract::Several studies have demonstrated an important association between altered lipid metabolism and the development of kidney injury because of a high-fat diet. Fructose is also closely associated with renal injury. We opted for a combination of fructose and saturated fats in a diet (DH) that is a model known to induce re...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12061624
更新日期:2020-06-01 00:00:00
abstract::Dietary habits in adolescence persist into adulthood; thus, it is important to identify the factors that influence adolescent diet and establish a healthy diet. This study aimed to examine the association between mothers' nutrition knowledge and their children's nutrient intake inadequacy among Japanese junior high sc...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12092801
更新日期:2020-09-13 00:00:00
abstract::Nonalcoholic fatty liver disease (NAFLD) is on the rise worldwide representing a public health issue. Its coexistence with obesity and other metabolic alterations is highly frequent. Therefore, current therapy interventions for NAFLD are mainly focused on progressive weight loss through modulation of overall calorie i...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu12123860
更新日期:2020-12-17 00:00:00
abstract::The World Health Organization promotes salt reduction as a best-buy strategy to reduce chronic diseases, and Member States have agreed to a 30% reduction target in mean population salt intake by 2025. Whilst the UK has made the most progress on salt reduction, South Africa was the first country to pass legislation for...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu6093672
更新日期:2014-09-16 00:00:00
abstract:BACKGROUND:The aim of this study was to investigate total water intake (TWI) from water, beverages and foods among Italian adults and the elderly. METHODS:Data of 2607 adults and the elderly, aged 18-75 years from the last national food consumption survey, INRAN-SCAI 2005-06, were used to evaluate the TWI. The INRAN-S...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu8110674
更新日期:2016-10-26 00:00:00