Abstract:
:A low Omega-3 Index (eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) in erythrocytes) is associated with cardiac, cerebral, and other health issues. Intake of EPA and DHA, but not of alpha-linolenic acid (ALA), increases the Omega-3 Index. We investigated bioavailability, safety, palatability and tolerability of EPA and DHA in a novel source: a variety of sausages. We screened 96 healthy volunteers, and recruited 44 with an Omega-3 Index <5%. Participants were randomly assigned to receive a variety of sausages enriched with approximately 250 mg EPA and DHA per 80 g (n = 22) daily for 8 weeks, or matching placebo sausages (n = 22). All sausages contained approximately 250 mg ALA/80 g. In the verum group, the mean Omega-3 Index increased from 4.18 ± 0.54 to 5.72 ± 0.66% (p < 0.001), while it remained unchanged in the placebo group. While ALA levels increased only in the placebo group, DPA levels increased in both groups. Inter-individual variability in the response was large. The mean increase of the Omega-3 Index per intake of EPA and DHA we observed was higher than for other sources previously studied, indicating superior bioavailability. As increasing production of EPA and DHA is difficult, improvements of bioavailability can facilitate reaching the target range for the Omega-3 Index (8-11%).
journal_name
Nutrientsjournal_title
Nutrientsauthors
Köhler A,Heinrich J,von Schacky Cdoi
10.3390/nu9060629subject
Has Abstractpub_date
2017-06-19 00:00:00issue
6issn
2072-6643pii
nu9060629journal_volume
9pub_type
杂志文章,随机对照试验相关文献
Nutrients文献大全abstract::Breast milk constitutes a dietary source of leptin, adiponectin and microRNAs (miRNAs) for newborns. Expression of miRNAs previously associated with maternal obesity, leptin or adiponectin function were assessed and their impact on infant weight analyzed. Milk samples were collected (at month 1, 2, and 3) from a cohor...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11112589
更新日期:2019-10-28 00:00:00
abstract::In New Zealand, there is a high prevalence of childhood poverty and food insecurity, which can impact a family's ability to provide high quality, nutrient dense foods for their children. In an attempt to increase the quality of the food consumed by children attending a decile two (low socio-economic) kindergarten and ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu9091031
更新日期:2017-09-18 00:00:00
abstract:BACKGROUND:Zinc is an indispensable element, being involved in many biological processes. Correspondingly, insufficient zinc intake in early youth can detrimentally affect the function of a growing body. The aim of this study was to determine zinc content in breast milk among lactating women in Latvia and factors (mate...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu10101438
更新日期:2018-10-05 00:00:00
abstract::Coffee is a blend of compounds related to gastrointestinal physiology. Given its popularity and the epidemiology of colorectal cancer, the impact of this beverage on public health could be considerable. Our aim was to provide an updated synthesis of the relationship between coffee consumption and the risk of colorecta...
journal_title:Nutrients
pub_type: 杂志文章,meta分析
doi:10.3390/nu11030694
更新日期:2019-03-24 00:00:00
abstract::Micronutrient delivery formulations based on nanoemulsions can enhance the absorption of nutrients and bioactives, and thus, are of great potential for food fortification and supplementation strategies. The aim was to evaluate the bioefficacy of vitamin D (VitD) encapsulated in nanoemulsions developed by sonication an...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11010075
更新日期:2019-01-02 00:00:00
abstract::The use of food supplements for weight loss purposes has rapidly gained popularity as the prevalence of obesity increases. Navigating through the vast, often low quality, literature available is challenging, as is providing informed advice to those asking for it. Herein, we provide a comprehensive literature revision ...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu12092873
更新日期:2020-09-20 00:00:00
abstract::The etiology of inflammatory bowel disease (IBD) is complex but is thought to be linked to an intricate interaction between the host's immune system, resident gut microbiome and environment, i.e., diet. One dietary component that has a major impact on IBD risk and disease management is fiber. Fiber intakes in pediatri...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu12103204
更新日期:2020-10-20 00:00:00
abstract::The aim of this paper is to analyze the a priori dietary indexes used in the studies that have evaluated the role of the Mediterranean Diet in influencing the risk of developing cardiovascular disease. All the studies show that this dietary pattern protects against cardiovascular disease, but studies show quite differ...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu7095367
更新日期:2015-09-16 00:00:00
abstract::Several diet-derived compounds have been reported to exert antioxidant, anti-proliferative and anti-angiogenic effects in numerous cancers and could be beneficial in cancer prevention. Olive oil production involves the generation of an aqueous phase defined as olive mill wastewater (OMWW), a polluting effluent rich in...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12040903
更新日期:2020-03-26 00:00:00
abstract::Infants rely on their innate immune systems to protect them from infection. Human milk (HM) contains fatty acids (FAs) and monoacylglycerols that are known to exhibit antiviral and antibacterial properties in vitro. The specific fat content of HM may potentially affect the efficacy of this antimicrobial activity. This...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu9091034
更新日期:2017-09-19 00:00:00
abstract:BACKGROUND:Patients with esophageal cancer (EC) have high rates of malnutrition due to tumor location and treatment-related toxicity. Various strategies are used to improve nutritional status in patients with EC including oral and enteral support. METHODS:We conducted a retrospective analysis to determine the impact o...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12103177
更新日期:2020-10-17 00:00:00
abstract:BACKGROUND:Several studies demonstrate that the provision of personalized lifestyle advice, based on genetics, can help motivate individuals to engage in greater nutrition and physical activity changes compared to the provision of population-based advice. The theoretical mechanism behind this phenomenon is poorly under...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12123768
更新日期:2020-12-08 00:00:00
abstract::Oligosaccharides (OS) are commonly added to infant formulas, however, their physiological impact, particularly on adult health programming, is poorly described. In adult animals, OS modify microbiota and stimulate colonic fermentation and enteroendocrine cell (EEC) activity. Since neonatal changes in microbiota and/or...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11091967
更新日期:2019-08-21 00:00:00
abstract::The aim of the present study was to investigate the effects of Atlantic salmon consumption on underlying biological mechanisms associated with anxiety such as heart rate variability (HRV) and heart rate (HR) as well as a measure of self-reported anxiety. Moreover, these biological and self-reported outcome measures we...
journal_title:Nutrients
pub_type: 杂志文章,随机对照试验
doi:10.3390/nu6125405
更新日期:2014-11-26 00:00:00
abstract::Nonalcoholic fatty liver disease (NAFLD) is one of the most common causes of chronic liver disease, sometimes ranges from simple steatosis to nonalcoholic steatohepatitis (NASH). Various hits including excessive hepatic steatosis, oxidative stress, apoptosis, and inflammation, contribute to NASH development. Gallic ac...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12051479
更新日期:2020-05-20 00:00:00
abstract::Plant-based diets are associated with reduced risk of lifestyle-induced chronic diseases. The thousands of phytochemicals they contain are implicated in cellular-based mechanisms to promote antioxidant defense and reduce inflammation. While recommendations encourage the intake of fruits and vegetables, most people fal...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu12102929
更新日期:2020-09-24 00:00:00
abstract::In chronic obstructive pulmonary disease (COPD), the bronchial epithelium is the first immune barrier that is triggered by cigarette smoke. Although vitamin D (vitD) has proven anti-inflammatory and antimicrobial effects in alveolar macrophages, little is known about the direct role of vitD on cigarette smoke-exposed ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11092138
更新日期:2019-09-06 00:00:00
abstract::Over a third of older adults in the U.S. experience significant vision loss, which decreases independence and is a biomarker of decreased health span. As the global aging population is expanding, it is imperative to uncover strategies to increase health span and reduce the economic burden of this age-related disease. ...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu12092862
更新日期:2020-09-18 00:00:00
abstract::The aim of this study was to investigate the association between habitual dietary intake for patients with diabetes and the content of family support for medical nutritional therapy (MNT). Analyzed were 289 Japanese with type 2 diabetes (men, 58.5%; mean age, 62.0 years; mean HbA1c, 53.4 mmol/mol) who completed the Fo...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12092649
更新日期:2020-08-31 00:00:00
abstract:BACKGROUND:Malnutrition is a frequent condition in the elderly, and is associated with prolonged hospitalization and increased mortality. However, the impacts of malnutrition among elderly patients with acute myocardial infarction have not been clarified yet. METHODS AND RESULTS:We enrolled 174 patients aged 65 years ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11020224
更新日期:2019-01-22 00:00:00
abstract::Infant dietary patterns tend to be insufficient sources of fruits, vegetables, and fiber, as well as excessive in salt, added sugars, and overall energy. Despite the serious long-term health risks associated with suboptimal fruit and vegetable intake, a large percentage of infants and toddlers in the U.S. do not consu...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu8050316
更新日期:2016-05-21 00:00:00
abstract::Accumulating epidemiological evidence suggests that anthocyanin intake is associated with reduced risks of cardiometabolic disorders, highlighting the importance of incorporating the phytochemical in our diets. Numerous food-based intervention studies have examined, in controlled meal settings, the role of anthocyanin...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu12123781
更新日期:2020-12-09 00:00:00
abstract::Fruits and vegetables are pivotal for a healthy diet due partly to their content in bioactive compounds. It is for this reason that we conducted a parallel study to unravel the possible effect on cardiometabolic parameters of the ingestion of anthocyanins, xanthophylls, or both groups of bioactives together in postmen...
journal_title:Nutrients
pub_type: 杂志文章,随机对照试验
doi:10.3390/nu11071533
更新日期:2019-07-05 00:00:00
abstract::We evaluated the concordance between visceral fat area (VFA) estimated by bioelectrical impedance analysis (BIA) or computed tomography (CT) in Korean subjects with a wide range in age and body mass index (BMI). In 1006 individuals (mean age 55.2 ± 11.8 (19-87) years, mean BMI 26.0 ± 3.5 (17-46) kg/m², 48.9% men), VFA...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu7125548
更新日期:2015-12-16 00:00:00
abstract::Maternal nutrition and lifestyle in pregnancy are important modifiable factors for both maternal and offspring's health. Although the Mediterranean diet has beneficial effects on health, recent studies have shown low adherence in Europe. This study aimed to assess the Mediterranean diet adherence in 266 pregnant women...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12082179
更新日期:2020-07-22 00:00:00
abstract:BACKGROUND AND AIM:Nickel (Ni)-rich foods can induce allergic contact mucositis (ACM) with irritable bowel syndrome (IBS)-like symptoms in predisposed subjects. Ni ACM has a high prevalence (>30%) in the general population and can be diagnosed by a Ni oral mucosa patch test (omPT). Many celiac disease (CD) patients on ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12082277
更新日期:2020-07-29 00:00:00
abstract::The assessment of diets in multi-ethnic cosmopolitan settings is challenging. A semi-quantitative 163-item food frequency questionnaire (FFQ) was developed for the adult Singapore population, and this study aimed to assess its reproducibility and relative validity against 24-h dietary recalls (24 h DR) and biomarkers....
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu9101059
更新日期:2017-09-25 00:00:00
abstract::The Recommended Dietary Allowance (RDA) is the nutrient intake considered to be sufficient to meet the requirements of 97.5% of the population. Recent reports revealed a statistical error in the calculation of the RDA for vitamin D opening the question of what the recommendation should be. We took a dual approach to a...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu7125527
更新日期:2015-12-04 00:00:00
abstract::Green tea is a popular drink consumed daily by millions of people around the world. Previous studies have shown that some polyphenol compounds from green tea possess anticancer activities. However, systemic evaluation was limited. In this study, we determined the cancer chemopreventive potentials of 10 representative ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu4111679
更新日期:2012-11-08 00:00:00
abstract::The aim of this study was to predict urinary creatinine excretion (UCr), creatinine clearance (CCr) and the glomerular filtration rate (GFR) from body composition analysis. Body cell mass (BCM) is the compartment which contains muscle mass, which is where creatinine is generated. BCM was measured with body impedance a...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu9060553
更新日期:2017-05-28 00:00:00