Abstract:
:The major part of iron present in plant foods such as cereals is largely unavailable for direct absorption in humans due to complexation with the negatively charged phosphate groups of phytate (myo-inositol (1,2,3,4,5,6)-hexakisphosphate). Human biology has not evolved an efficient mechanism to naturally release iron from iron phytate complexes. This narrative review will evaluate the quantitative significance of phytase-catalysed iron release from cereal foods. In vivo studies have shown how addition of microbially derived phytases to cereal-based foods has produced increased iron absorption via enzyme-catalysed dephosphorylation of phytate, indicating the potential of this strategy for preventing and treating iron deficiency anaemia. Despite the immense promise of this strategy and the prevalence of iron deficiency worldwide, the number of human studies elucidating the significance of phytase-mediated improvements in iron absorption and ultimately in iron status in particularly vulnerable groups is still low. A more detailed understanding of (1) the uptake mechanism for iron released from partially dephosphorylated phytate chelates, (2) the affinity of microbially derived phytases towards insoluble iron phytate complexes, and (3) the extent of phytate dephosphorylation required for iron release from inositol phosphates is warranted. Phytase-mediated iron release can improve iron absorption from plant foods. There is a need for development of innovative strategies to obtain better effects.
journal_name
Nutrientsjournal_title
Nutrientsauthors
Nielsen AV,Tetens I,Meyer ASdoi
10.3390/nu5083074subject
Has Abstractpub_date
2013-08-02 00:00:00pages
3074-98issue
8issn
2072-6643pii
nu5083074journal_volume
5pub_type
杂志文章,评审相关文献
Nutrients文献大全abstract::Policies to promote healthy foods in early care and education (ECE) in the United States exist, but few have been prospectively evaluated. In South Carolina, a statewide program serving low-income children in ECE enacted new policies promoting healthy foods. We conducted an evaluation to measure changes in dietary int...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12061753
更新日期:2020-06-11 00:00:00
abstract::Childhood is a period of brain growth and maturation. The long chain omega-3 fatty acid, docosahexaenoic acid (DHA), is a major lipid in the brain recognized as essential for normal brain function. In animals, low brain DHA results in impaired learning and behavior. In infants, DHA is important for optimal visual and ...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu5072777
更新日期:2013-07-19 00:00:00
abstract:BACKGROUND:The presence of β-glucans and phenolic compounds in Lentinus edodes suggests this mushroom can be used as a nutritional supplement. Two gestational conditions (before and after fetus implantation) were evaluated, and Lentinus edodes exposure was performed in diabetes mellitus rat model induced by streptozoto...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11112720
更新日期:2019-11-09 00:00:00
abstract::Oxidative Balance Scores (OBSs) are tools that have emerged to evaluate the global balance of individuals' oxidation-reduction status. The aim was to compare OBSs available in the literature regarding their characteristics and associations with chronic diseases in epidemiological studies. Studies that developed OBSs w...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11040774
更新日期:2019-04-03 00:00:00
abstract::The loss of skeletal muscle mass with energy deficit is thought to be due to protein breakdown by the autophagy-lysosome and the ubiquitin-proteasome systems. We studied the main signaling pathways through which exercise can attenuate the loss of muscle mass during severe energy deficit (5500 kcal/day). Overweight men...
journal_title:Nutrients
pub_type: 杂志文章,随机对照试验
doi:10.3390/nu11112824
更新日期:2019-11-19 00:00:00
abstract:BACKGROUND:Bifidobacterium represents an important early life microbiota member. Specific bifidobacterial components, exopolysaccharides (EPS), positively modulate host responses, with purified EPS also suggested to impact microbe-microbe interactions by acting as a nutrient substrate. Thus, we determined the longitudi...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12040948
更新日期:2020-03-29 00:00:00
abstract::Heat stress conditions lead to neuroinflammation, neuronal death, and memory loss in animals. Coptidis Rhizoma (CR) exhibits potent fever-reducing effects and has been used as an important traditional medicinal herb for treating fever. However, to date, the effects of antipyretic CR on heat-induced brain damages have ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu9101057
更新日期:2017-09-23 00:00:00
abstract::Soy is a basic food ingredient of traditional Asian cuisine used for thousands of years. In Western countries, soybeans have been introduced about a hundred years ago and recently they are mainly used for surrogate foods production. Soy and soy foods are common nutritional solutions for vegetarians, due to their high ...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu10010043
更新日期:2018-01-05 00:00:00
abstract::Hand osteoarthritis (OA) is a degenerative joint disease which leads to pain and disability. Recent studies focus on the role of obesity and metabolic syndrome in inducing or worsening joint damage in hand OA patients, suggesting that chronic low-grade systemic inflammation may represent a possible linking factor. The...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu12113469
更新日期:2020-11-12 00:00:00
abstract::Understanding the regulation of gene activities depending on DNA methylation has been the subject of much recent study. However, although polymorphisms of the HTR2A gene have been associated with both obesity and psychiatric disorders, the role of HTR2A gene methylation in these illnesses remains uncertain. The aim of...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu6062387
更新日期:2014-06-23 00:00:00
abstract::Previous research investigating the relationship between parents' and children's diets has focused on single foods or nutrients, and not on global diet, which may be more important for good health. The aim of the study was to investigate the relationship between parental diet quality and child dietary patterns. A cros...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu9050483
更新日期:2017-05-11 00:00:00
abstract::Optimising the diet and weight of women prior to and during pregnancy is of paramount importance to both maternal and offspring health. In women who become pregnant after bariatric surgery, evidence suggests a better overall obstetric outcome in comparison to women with severe obesity managed conservatively. Historica...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11092116
更新日期:2019-09-05 00:00:00
abstract::The synergies and cumulative effects among different foods and nutrients are what produce the benefits of a healthy dietary pattern. Diets and dietary patterns are a major environmental factor that we are exposed to several times a day. People can learn how to control this behavior in order to promote healthy living a...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu8040218
更新日期:2016-04-13 00:00:00
abstract::Awareness and knowledge of nutrient-dense foods are important for older adults to help them make dietary choices that support a food-first approach to healthy aging. This is especially important since age is a major risk factor for chronic disease and the proportion of older adults in North America is increasing. Bean...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11112680
更新日期:2019-11-05 00:00:00
abstract::As malnutrition is common in patients with Alzheimer's disease (AD), we evaluated nutritional status and body composition of patients with AD, mild cognitive impairment (MCI) and controls, and studied associations of AD biomarkers and cognitive performance with nutritional status and body composition. We included 552 ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11051161
更新日期:2019-05-23 00:00:00
abstract::Adequate calorie restriction (CR) as a healthy lifestyle is recommended not only for people with metabolic disorders but also for healthy adults. Previous studies have mainly focused on the beneficial metabolic effects of CR on obese subjects, while its effects on non-obese subjects are still scarce. Here, we conducte...
journal_title:Nutrients
pub_type: 临床试验,杂志文章
doi:10.3390/nu12030631
更新日期:2020-02-27 00:00:00
abstract::An activity-guided search for compounds influencing glucose metabolism in extracts from aronia (Aronia melanocarpa, A.), pomegranate (Punica granatum L., P.), and red grape (Vitis vinifera, RG) was carried out. The three extracts were fractionated by means of membrane chromatography to separate the anthocyanins from o...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11051166
更新日期:2019-05-24 00:00:00
abstract::As the population is aging rapidly, there is a strong increase in the number of individuals with chronic disease and physical limitations. The decrease in skeletal muscle mass and function (sarcopenia) and the increase in fat mass (obesity) are important contributors to the development of physical limitations, which a...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu10050605
更新日期:2018-05-12 00:00:00
abstract::Crocin, a major constituent of Gardenia jasminoides, is a natural colorant carotenoid compound that has been reported to have anti-inflammatory effects. This study investigated the therapeutic effects of crocin on mice with atopic dermatitis induced by Dermatophagoides farinae crude extract, which is a common environm...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu10111625
更新日期:2018-11-02 00:00:00
abstract::Studies suggest that haem, non-haem iron and total iron intake may be related to non-communicable diseases, especially metabolic syndrome. This study was undertaken to investigate the association of haem, non-haem iron and total iron intake with metabolic syndrome and its components. A cross-sectional population-based...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu10030314
更新日期:2018-03-07 00:00:00
abstract::Various aspects of protein intake are thought to be crucial for the prevention of sarcopenia in older adults. Information about the day-to-day variation in these aspects is lacking. Our objective was to examine whether daily protein intake, protein distribution across meals, number of meals providing adequate protein,...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu10091217
更新日期:2018-09-03 00:00:00
abstract::Both vitamin D deficiency and cognitive impairment are common in patients with chronic kidney disease (CKD). Vitamin D exerts neuroprotective and regulatory roles in the central nervous system. Hypovitaminosis D has been associated with muscle weakness and bone loss, cardiovascular diseases (hypertension, diabetes and...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu8050291
更新日期:2016-05-13 00:00:00
abstract::The effect of the betaine: homocysteine methyltransferase BHMT c.716G>A (G: guanosine; A: adenosine) single nucleotide polymorphism (SNP) on the BHMT pathway is unknown during pregnancy. We hypothesised that it impairs betaine to dimethylglycine conversion and that folate status modifies its effect. We studied 612 wom...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu8100621
更新日期:2016-10-09 00:00:00
abstract::Vitamin K is a composite term referring to a group of fat-soluble vitamins that function as a cofactor for the enzyme γ-glutamyl carboxylase (GGCX), which activates a number of vitamin K-dependent proteins (VKDPs) involved in haemostasis and vascular and bone health. Accumulating evidence demonstrates that chronic kid...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu11010168
更新日期:2019-01-14 00:00:00
abstract::It has been suggested that maternal nutrition during gestation is involved in an offspring's intestinal development. The aim of this study was therefore to evaluate the effects of maternal energy on the growth and small intestine development of offspring. After mating, twenty gilts (Large White (LW) breeding, body wei...
journal_title:Nutrients
pub_type: 杂志文章,随机对照试验
doi:10.3390/nu8050258
更新日期:2016-05-05 00:00:00
abstract::Diet may influence the risk of ischemic stroke by several mechanisms. A potential and hitherto unknown mechanism may relate to an effect on the lipophilic index, which is a new and convenient indicator of membrane fluidity. This study investigated the association between the adipose tissue lipophilic index and ischemi...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu10111570
更新日期:2018-10-23 00:00:00
abstract::Taste is influenced by several factors. However, whether habitual exercise level is associated with differences in taste perception has received little investigation. The aim of this study was to determine if habitual exercise is associated with differences in taste perception in men. Active (n = 16) and inactive (n =...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11010155
更新日期:2019-01-12 00:00:00
abstract::This cross-sectional, exploratory study aimed to (1) develop an obesity risk score using a comprehensive set of variables assessing mothers’ intrapersonal weight-related characteristics and those of their homes’ interpersonal and physical environments, and (2) determine how weight-related characteristics d...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu10060781
更新日期:2018-06-17 00:00:00
abstract::The present study aimed to assess the feasibility and reliability of an a3utomatic food intake measurement device in estimating energy intake from energy-dense foods. Eighteen volunteers aged 20-36 years were recruited from the University of Padova. The device used in the present study was the Bite Counter (Bite Techn...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11051170
更新日期:2019-05-24 00:00:00
abstract::This systematic review aims to evaluate the association of adiponectin (ADIPOQ) and leptin (LEP) gene variants with energy intake. Cross-sectional, cohort, and case⁻control studies that reported an association of leptin and/or adiponectin gene variants with energy intake were included in this review. Human studies wit...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11040750
更新日期:2019-03-30 00:00:00