Abstract：
:Vitamin K is a composite term referring to a group of fat-soluble vitamins that function as a cofactor for the enzyme γ-glutamyl carboxylase (GGCX), which activates a number of vitamin K-dependent proteins (VKDPs) involved in haemostasis and vascular and bone health. Accumulating evidence demonstrates that chronic kidney disease (CKD) patients suffer from subclinical vitamin K deficiency, suggesting that this represents a population at risk for the biological consequences of poor vitamin K status. This deficiency might be caused by exhaustion of vitamin K due to its high requirements by vitamin K-dependent proteins to inhibit calcification.
journal_name
Nutrientsjournal_title
Nutrientsauthors
Cozzolino M,Mangano M,Galassi A,Ciceri P,Messa P,Nigwekar Sdoi
10.3390/nu11010168subject
Has Abstractpub_date
2019-01-14 00:00:00issue
1issn
2072-6643pii
nu11010168journal_volume
11pub_type
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