The relationship of docosahexaenoic acid (DHA) with learning and behavior in healthy children: a review.

Abstract:

:Childhood is a period of brain growth and maturation. The long chain omega-3 fatty acid, docosahexaenoic acid (DHA), is a major lipid in the brain recognized as essential for normal brain function. In animals, low brain DHA results in impaired learning and behavior. In infants, DHA is important for optimal visual and cognitive development. The usual intake of DHA among toddlers and children is low and some studies show improvements in cognition and behavior as the result of supplementation with polyunsaturated fatty acids including DHA. The purpose of this review was to identify and evaluate current knowledge regarding the relationship of DHA with measures of learning and behavior in healthy school-age children. A systematic search of the literature identified 15 relevant publications for review. The search found studies which were diverse in purpose and design and without consistent conclusions regarding the treatment effect of DHA intake or biomarker status on specific cognitive tests. However, studies of brain activity reported benefits of DHA supplementation and over half of the studies reported a favorable role for DHA or long chain omega-3 fatty acids in at least one area of cognition or behavior. Studies also suggested an important role for DHA in school performance.

journal_name

Nutrients

journal_title

Nutrients

authors

Kuratko CN,Barrett EC,Nelson EB,Salem N Jr

doi

10.3390/nu5072777

subject

Has Abstract

pub_date

2013-07-19 00:00:00

pages

2777-810

issue

7

issn

2072-6643

pii

nu5072777

journal_volume

5

pub_type

杂志文章,评审
  • An Extract of Olive Mill Wastewater Downregulates Growth, Adhesion and Invasion Pathways in Lung Cancer Cells: Involvement of CXCR4.

    abstract::Several diet-derived compounds have been reported to exert antioxidant, anti-proliferative and anti-angiogenic effects in numerous cancers and could be beneficial in cancer prevention. Olive oil production involves the generation of an aqueous phase defined as olive mill wastewater (OMWW), a polluting effluent rich in...

    journal_title:Nutrients

    pub_type: 杂志文章

    doi:10.3390/nu12040903

    authors: Gallazzi M,Festa M,Corradino P,Sansone C,Albini A,Noonan DM

    更新日期:2020-03-26 00:00:00

  • Anthropometry, Body Composition and Resting Energy Expenditure in Human.

    abstract::Anthropometry (from the Greek anthropos: human, and metron: measure) refers to the systematic collection and correlation of measurements of human individuals, including the systematic measurement of the physical characteristics of the human body, primarily body weight, body size, and shape [...]. ...

    journal_title:Nutrients

    pub_type: 社论

    doi:10.3390/nu11081891

    authors: Tur JA,Bibiloni MDM

    更新日期:2019-08-14 00:00:00

  • Polyphenols and IUGR Pregnancies: Effects of Maternal Hydroxytyrosol Supplementation on Hepatic Fat Accretion and Energy and Fatty Acids Profile of Fetal Tissues.

    abstract::Maternal supplementation with hydroxytyrosol, a polyphenol present in olive leaves and fruits, is a highly promising strategy to improve the oxidative and metabolic status of fetuses at risk of intrauterine growth restriction, which may diminish the appearance of low-birth-weight neonates. The present study aimed to d...

    journal_title:Nutrients

    pub_type: 杂志文章

    doi:10.3390/nu11071534

    authors: Garcia-Contreras C,Vazquez-Gomez M,Pardo Z,Heras-Molina A,Encinas T,Torres-Rovira L,Astiz S,Nieto R,Ovilo C,Gonzalez-Bulnes A,Isabel B

    更新日期:2019-07-05 00:00:00

  • Metabolic Syndrome: Past, Present and Future.

    abstract::Most clinicians and health professionals have heard or read about metabolic syndrome [...]. ...

    journal_title:Nutrients

    pub_type: 社论

    doi:10.3390/nu12113501

    authors: Lemieux I,Després JP

    更新日期:2020-11-14 00:00:00

  • Fermented Brown Rice and Rice Bran with Aspergillus oryzae (FBRA) Prevents Inflammation-Related Carcinogenesis in Mice, through Inhibition of Inflammatory Cell Infiltration.

    abstract::We have established an inflammation-related carcinogenesis model in mouse, in which regressive QR-32 cells subcutaneously co-implanted with a foreign body-gelatin sponge-convert themselves into lethal tumors due to massive infiltration of inflammatory cells into the sponge. Animals were fed with a diet containing 5% o...

    journal_title:Nutrients

    pub_type: 杂志文章

    doi:10.3390/nu7125531

    authors: Onuma K,Kanda Y,Suzuki Ikeda S,Sakaki R,Nonomura T,Kobayashi M,Osaki M,Shikanai M,Kobayashi H,Okada F

    更新日期:2015-12-08 00:00:00

  • Horticultural Activity Type, Psychological Well-Being, and Fruit and Vegetable Intake.

    abstract::The purpose of this study was to explore the effect of the frequency of participation in horticultural activity types on psychological well-being and fruit and vegetable intake. The study sought to understand the mediating effect of psychological well-being between the frequency of types of horticultural activities an...

    journal_title:Nutrients

    pub_type: 杂志文章

    doi:10.3390/nu12113296

    authors: Zhong YQ,Tu HM

    更新日期:2020-10-28 00:00:00

  • High-Protein Diet Containing Dairy Products is Associated with Low Body Mass Index and Glucose Concentrations: A Cross-Sectional Study.

    abstract::The aim was to evaluate whether the ingestion of a high protein diet containing dairy protein is associated with anthropometric indicators of adiposity and blood glucose. METHODS:A cross-sectional study was conducted with volunteers of 20-89 years of age who performed leisure physical activity. We assessed dietary in...

    journal_title:Nutrients

    pub_type: 杂志文章

    doi:10.3390/nu11061384

    authors: Giglio BM,Duarte VIR,Galvão AF,Marini ACB,Schincaglia RM,Mota JF,Souza LB,Pimentel GD

    更新日期:2019-06-20 00:00:00

  • An Evaluation of the Pea Pod System for Assessing Body Composition of Moderately Premature Infants.

    abstract::(1) BACKGROUND: Assessing the quality of growth in premature infants is important in order to be able to provide them with optimal nutrition. The Pea Pod device, based on air displacement plethysmography, is able to assess body composition of infants. However, this method has not been sufficiently evaluated in prematu...

    journal_title:Nutrients

    pub_type: 杂志文章

    doi:10.3390/nu8040238

    authors: Forsum E,Olhager E,Törnqvist C

    更新日期:2016-04-22 00:00:00

  • Effects of Matcha Green Tea Powder on Cognitive Functions of Community-Dwelling Elderly Individuals.

    abstract::Matcha Green Tea Powder contains a variety of active ingredients beneficial to health, such as tea catechins, lutein and vitamin K. It is also known that these ingredients confer benefits upon cognitive functions of elderly people. Therefore, we aimed to investigate the relationship between a daily supplementation of ...

    journal_title:Nutrients

    pub_type: 杂志文章

    doi:10.3390/nu12123639

    authors: Sakurai K,Shen C,Ezaki Y,Inamura N,Fukushima Y,Masuoka N,Hisatsune T

    更新日期:2020-11-26 00:00:00

  • Impact of Food Additives on Gut Homeostasis.

    abstract::In physiological conditions, the gut is heavily infiltrated with various subsets of inflammatory cells, whose activity is tightly controlled by counter-regulatory mechanisms. Defects in such mechanisms can favour the development of chronic intestinal disorders, such as Crohn's disease (CD) and ulcerative colitis (UC),...

    journal_title:Nutrients

    pub_type: 杂志文章

    doi:10.3390/nu11102334

    authors: Laudisi F,Stolfi C,Monteleone G

    更新日期:2019-10-01 00:00:00

  • Sedentary Behavior and Alcohol Consumption Increase Breast Cancer Risk Regardless of Menopausal Status: A Case-Control Study.

    abstract::Identification of modifiable risk factors for breast cancer is critical for primary prevention of the disease. The aim of this study was to evaluate how certain lifestyle variables modify the chances of developing breast cancer based on menopausal status. A case-control study was performed in a group of 542 women, 197...

    journal_title:Nutrients

    pub_type: 杂志文章

    doi:10.3390/nu11081871

    authors: Godinho-Mota JCM,Gonçalves LV,Mota JF,Soares LR,Schincaglia RM,Martins KA,Freitas-Junior R

    更新日期:2019-08-12 00:00:00

  • Vitamin K Status in Adherent and Non-Adherent Patients with Phenylketonuria: A Cross-Sectional Study.

    abstract::This is the first study to evaluate vitamin K status in relation to dietary intake and phenylalanine dietary compliance in patients with phenylketonuria (PKU). The dietary and PKU formula intake of vitamin K was calculated in 34 PKU patients, with vitamin K status determined by the measurement of prothrombin induced b...

    journal_title:Nutrients

    pub_type: 杂志文章

    doi:10.3390/nu12061772

    authors: Mozrzymas R,Walkowiak D,Drzymała-Czyż S,Krzyżanowska-Jankowska P,Duś-Żuchowska M,Kałużny Ł,Walkowiak J

    更新日期:2020-06-14 00:00:00

  • Actigraphic Sleep and Dietary Macronutrient Intake in Children Aged 6-9 Years Old: A Pilot Study.

    abstract::The objective of this study was to examine the relationship between different sleep parameters and energy and macronutrient intake in school-aged children. A total of 203 children 6 to 9 years of age participated in this cross-sectional study. Anthropometric measurements were taken first. Diet was assessed with 3-day ...

    journal_title:Nutrients

    pub_type: 杂志文章

    doi:10.3390/nu11112568

    authors: Coronado Ferrer S,Peraita-Costa I,Llopis-Morales A,Picó Y,Soriano JM,Nieto FJ,Llopis-González A,Morales-Suarez-Varela M

    更新日期:2019-10-24 00:00:00

  • Iron Metabolism Dysregulation and Cognitive Dysfunction in Pediatric Obesity: Is There a Connection?

    abstract::Obesity and iron deficiency (ID) are two of the most common nutritional disorders in the world. In children both conditions deserve particular attention. Several studies revealed an association between obesity and iron deficiency in children and, in some cases, a reduced response to oral supplementation. The connectin...

    journal_title:Nutrients

    pub_type: 杂志文章,评审

    doi:10.3390/nu7115458

    authors: Grandone A,Marzuillo P,Perrone L,Del Giudice EM

    更新日期:2015-11-06 00:00:00

  • The Impact of Integrated Infant and Young Child Feeding and Micronutrient Powder Intervention on Feeding Practices and Anemia in Children Aged 6-23 Months in Madagascar.

    abstract::This study assesses the impact of an integrated infant and young child feeding (IYCF) and micronutrient powder (MNP) intervention on children's risk of anemia and IYCF practices in Madagascar. Quantitative baseline and endline surveys were conducted in representative households with children 6-23 months from two distr...

    journal_title:Nutrients

    pub_type: 杂志文章

    doi:10.3390/nu9060581

    authors: Locks LM,Reerink I,Tucker Brown A,Gnegne S,Ramalanjaona N,Nanama S,Duggan CP,Garg A

    更新日期:2017-06-07 00:00:00

  • Maintaining the Outcomes of a Successful Weight Gain Prevention Intervention in Mid-Age Women: Two Year Results from the 40-Something Randomized Control Trial.

    abstract::Despite the life stage of menopause being identified as a high risk for weight gain, there are few obesity prevention interventions for this target group, and no evidence on maintenance of intervention effects after intervention support is withdrawn. In the 40-Something Randomized Controlled Trial (RCT) (ACTRN12611000...

    journal_title:Nutrients

    pub_type: 临床试验,杂志文章

    doi:10.3390/nu11051100

    authors: Williams LT,Collins CE,Morgan PJ,Hollis JL

    更新日期:2019-05-17 00:00:00

  • Characterization of Breakfast Cereals Available in the Mexican Market: Sodium and Sugar Content.

    abstract::Preschool Mexican children consume 7% of their total energy intake from processed breakfast cereals. This study characterized the nutritional quality and labelling (claims and Guideline Daily Amount (GDA)) of the packaged breakfast cereals available in the Mexican market. Photographs of all breakfast cereals available...

    journal_title:Nutrients

    pub_type: 杂志文章

    doi:10.3390/nu9080884

    authors: Nieto C,Rincon-Gallardo Patiño S,Tolentino-Mayo L,Carriedo A,Barquera S

    更新日期:2017-08-16 00:00:00

  • Performance of Waist-To-Height Ratio, Waist Circumference, and Body Mass Index in Discriminating Cardio-Metabolic Risk Factors in a Sample of School-Aged Mexican Children.

    abstract::The most common tools used to screen for abdominal obesity are waist circumference (WC) and waist-to-height ratio (WHtR); the latter may represent a more suitable tool for the general non-professional population. The objective of this study was to evaluate the association of WHtR, WC, and body mass index with lipidic ...

    journal_title:Nutrients

    pub_type: 杂志文章

    doi:10.3390/nu10121850

    authors: Aguilar-Morales I,Colin-Ramirez E,Rivera-Mancía S,Vallejo M,Vázquez-Antona C

    更新日期:2018-12-01 00:00:00

  • Comparisons of the Postprandial Inflammatory and Endotoxaemic Responses to Mixed Meals in Young and Older Individuals: A Randomised Trial.

    abstract::Postprandial inflammation and endotoxaemia are determinants of cardiovascular and metabolic disease risk which are amplified by high fat meals. We aimed to examine the determinants of postprandial inflammation and endotoxaemia in older and younger adults following a high fat mixed meal. In a randomised cross-over tria...

    journal_title:Nutrients

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.3390/nu9040354

    authors: Milan AM,Pundir S,Pileggi CA,Markworth JF,Lewandowski PA,Cameron-Smith D

    更新日期:2017-04-02 00:00:00

  • The Association of Serum Levels of Leptin and Ghrelin with the Dietary Fat Content in Non-Obese Women with Polycystic Ovary Syndrome.

    abstract::Women with polycystic ovary syndrome (PCOS) are at an increased risk of developing insulin resistance and abdominal obesity in the state of an improper diet balance. Leptin is a peptide considered to be a satiety hormone that plays an important role in the long-term energy balance, whereas ghrelin is a hormone that co...

    journal_title:Nutrients

    pub_type: 杂志文章

    doi:10.3390/nu12092753

    authors: Polak AM,Krentowska A,Łebkowska A,Buczyńska A,Adamski M,Adamska-Patruno E,Fiedorczuk J,Krętowski AJ,Kowalska I,Adamska A

    更新日期:2020-09-10 00:00:00

  • Evaluation of the Proximity of Singaporean Children's Dietary Habits to Food-Based Dietary Guidelines.

    abstract::Dietary habits in children may not only impact current health status but could also shape future, lifelong dietary choices. Dietary intake data in Singaporean children are limited. The current study aimed to define the overall diet quality of Singaporean children using an existing cross-sectional dataset and to consid...

    journal_title:Nutrients

    pub_type: 杂志文章

    doi:10.3390/nu11112615

    authors: Brownlee IA,Low J,Duriraju N,Chun M,Ong JXY,Tay ME,Hendrie GA,Santos-Merx L

    更新日期:2019-11-01 00:00:00

  • Intake of 25-Hydroxyvitamin D3 May Reduce the Severity of Upper Respiratory Tract Infection: Post hoc Analysis of a Randomized, Double-Blind, Placebo-Controlled, Parallel Group Comparison Study.

    abstract::To evaluate the effects of 25-hydroxyvitamin D3 (25OHD) on symptoms at the onset of the upper respiratory tract infection (URTI) in subjects with insufficient or deficient serum 25-hydroxyvitamin D levels, we conducted a post hoc analysis of data from a randomized, placebo-controlled study; the subjects received 10 μg...

    journal_title:Nutrients

    pub_type: 杂志文章

    doi:10.3390/nu12123769

    authors: Shimizu Y,Ito Y,Uotsu N,Yui K

    更新日期:2020-12-08 00:00:00

  • Adipokines and Endotoxemia Correlate with Hepatic Steatosis in Non-Alcoholic Fatty Liver Disease (NAFLD).

    abstract::(1) Background: The etiology of non-alcoholic fatty liver disease (NAFLD) is multifactorial. Dietary composition has been implicated as a factor modulating intestinal barrier and could affect disease severity. The aim of this study was to evaluate dietary intake and markers of intestinal permeability in patients with ...

    journal_title:Nutrients

    pub_type: 杂志文章

    doi:10.3390/nu12030699

    authors: Nier A,Huber Y,Labenz C,Michel M,Bergheim I,Schattenberg JM

    更新日期:2020-03-05 00:00:00

  • Does Incorporating Gender Differences into Quantifying a Food Frequency Questionnaire Influence the Association of Total Energy Intake with All-Cause and Cause-Specific Mortality?

    abstract::This study aims to evaluate whether incorporating gender differences in portion sizes as part of quantifying a food frequency questionnaire influences the association of total energy intake with mortality. The analysis included 156,434 participants (70,142 men and 86,292 women) in the Multiethnic Cohort Study, aged 45...

    journal_title:Nutrients

    pub_type: 杂志文章

    doi:10.3390/nu12102914

    authors: Kang M,Park SY,Boushey CJ,Wilkens LR,Le Marchand L,Hankin JH,Paik HY

    更新日期:2020-09-23 00:00:00

  • Crocin Ameliorates Atopic Dermatitis Symptoms by down Regulation of Th2 Response via Blocking of NF-κB/STAT6 Signaling Pathways in Mice.

    abstract::Crocin, a major constituent of Gardenia jasminoides, is a natural colorant carotenoid compound that has been reported to have anti-inflammatory effects. This study investigated the therapeutic effects of crocin on mice with atopic dermatitis induced by Dermatophagoides farinae crude extract, which is a common environm...

    journal_title:Nutrients

    pub_type: 杂志文章

    doi:10.3390/nu10111625

    authors: Sung YY,Kim HK

    更新日期:2018-11-02 00:00:00

  • Safety and Efficacy of Probiotic Supplementation in Reducing the Incidence of Infections and Modulating Inflammation in the Elderly with Feeding Tubes: A Pilot, Double-Blind, Placebo-Controlled Study, "IntegPRO".

    abstract::A double-blind, placebo-controlled study was performed in a sample of geriatric patients treated with home enteral nutrition (HEN) to analyze the efficacy of a probiotic supplement Proxian®, which contains Lactiplantibacillus plantarum LP01 (LMG P-21021), Lentilactobacillus buchneri Lb26 (DSM 16341), Bifidobacterium a...

    journal_title:Nutrients

    pub_type: 杂志文章

    doi:10.3390/nu13020391

    authors: Orlandoni P,Jukic Peladic N,Amoruso A,Pane M,Di Rosa M,Vedruccio J,Santini F

    更新日期:2021-01-27 00:00:00

  • Development of Criteria for a Positive Front-of-Package Food Labeling: The Israeli Case.

    abstract::Efforts to shape the food environment are aimed at reducing diet-related co-morbidities. Front-of-package labeling (FOPL) may support the consumers to make an informed decision at the point of purchase and encourage industry to reformulate food products. The Israeli Ministry of Health (MOH) implemented a unique FOPL s...

    journal_title:Nutrients

    pub_type: 杂志文章

    doi:10.3390/nu12061875

    authors: Gillon-Keren M,Kaufman-Shriqui V,Goldsmith R,Safra C,Shai I,Fayman G,Berry E,Tirosh A,Dicker D,Froy O,Gordon E,Chavia Ben-Yosef AC,Nitsan L,Altman H,Blaychfeld-Magnazi M,Endevelt R

    更新日期:2020-06-23 00:00:00

  • Maternal Folate Status and the BHMT c.716G>A Polymorphism Affect the Betaine Dimethylglycine Pathway during Pregnancy.

    abstract::The effect of the betaine: homocysteine methyltransferase BHMT c.716G>A (G: guanosine; A: adenosine) single nucleotide polymorphism (SNP) on the BHMT pathway is unknown during pregnancy. We hypothesised that it impairs betaine to dimethylglycine conversion and that folate status modifies its effect. We studied 612 wom...

    journal_title:Nutrients

    pub_type: 杂志文章

    doi:10.3390/nu8100621

    authors: Colomina JM,Cavallé-Busquets P,Fernàndez-Roig S,Solé-Navais P,Fernandez-Ballart JD,Ballesteros M,Ueland PM,Meyer K,Murphy MM

    更新日期:2016-10-09 00:00:00

  • Is Trabecular Bone Score Valuable in Bone Microstructure Assessment after Gastric Bypass in Women with Morbid Obesity?

    abstract:INTRODUCTION:The effects of bariatric surgery on skeletal health raise many concerns. Trabecular bone score (TBS) is obtained through the analysis of lumbar spine dual X-ray absorptiometry (DXA) images and allows an indirect assessment of skeletal microarchitecture (MA). The aim of our study was to evaluate the changes...

    journal_title:Nutrients

    pub_type: 杂志文章

    doi:10.3390/nu9121314

    authors: Marengo AP,Guerrero Pérez F,San Martín L,Monseny R,Casajoana A,Valera R,Virgili N,Simó Servat A,Prats A,Gómez-Vaquero C,Vilarrasa N

    更新日期:2017-12-02 00:00:00

  • Perioperative immunonutrition in well-nourished patients undergoing surgery for head and neck cancer: evaluation of inflammatory and immunologic outcomes.

    abstract::Limited work is available on the benefits of nutritional support enriched with arginine and n-3 fatty acids in surgical patients with head and neck cancer, particularly if well-nourished. We conducted a pilot study in these patients to examine effects on inflammatory markers and clinical outcome. Patients scheduled fo...

    journal_title:Nutrients

    pub_type: 杂志文章,随机对照试验

    doi:10.3390/nu5041186

    authors: Turnock A,Calder PC,West AL,Izzard M,Morton RP,Plank LD

    更新日期:2013-04-09 00:00:00