Abstract:
:Hand osteoarthritis (OA) is a degenerative joint disease which leads to pain and disability. Recent studies focus on the role of obesity and metabolic syndrome in inducing or worsening joint damage in hand OA patients, suggesting that chronic low-grade systemic inflammation may represent a possible linking factor. The gut microbiome has a crucial metabolic role which is fundamental for immune system development, among other important functions. Intestinal microbiota dysbiosis may favour metabolic syndrome and low-grade inflammation-two important components of hand OA onset and evolution. The aim of this narrative is to review the recent literature concerning the possible contribution of dysbiosis to hand OA onset and progression, and to discuss the importance of gut dysbiosis on general health and disease.
journal_name
Nutrientsjournal_title
Nutrientsauthors
Silvestre MP,Rodrigues AM,Canhão H,Marques C,Teixeira D,Calhau C,Branco Jdoi
10.3390/nu12113469subject
Has Abstractpub_date
2020-11-12 00:00:00issue
11issn
2072-6643pii
nu12113469journal_volume
12pub_type
杂志文章,评审相关文献
Nutrients文献大全abstract::Flavonoids have been implicated in the prevention of cardiovascular diseases (CVD). In a prospective approach, we investigated whether habitual flavonoid intake from fruit, vegetables and juices (FlavFVJ) during adolescence is associated with adult levels of serum lipids, one of the main CVD risk factors. This analysi...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu10040488
更新日期:2018-04-14 00:00:00
abstract::Preterm birth is an increasing worldwide problem. Prematurity is the second most common cause of death in children under 5 years of age. It is associated with a higher risk of several pathologies in the perinatal period and adulthood. Maternal milk, a complex fluid with several bioactive factors, is the best option fo...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu11061307
更新日期:2019-06-10 00:00:00
abstract::The aim of this 12-month retrospective study was to evaluate differences in the outcomes of denosumab alone or denosumab combined with vitamin D and calcium supplementation in patients having osteoporosis (OP) with rheumatoid arthritis (RA). Patients were divided into the denosumab monotherapy group (denosumab group, ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu9050428
更新日期:2017-04-26 00:00:00
abstract::Observational studies have suggested inconsistent findings on the relationship between dairy products intake and endometrial cancer risk. This study aimed to conduct a meta-analysis to evaluate this correlation; moreover, databases including PubMed, ISI Web of Science, and Embase were screened for relevant studies up ...
journal_title:Nutrients
pub_type: 杂志文章,meta分析,评审
doi:10.3390/nu10010025
更新日期:2017-12-28 00:00:00
abstract::In China, the rates of chronic diseases characteristic of countries in nutritional transition have been increasing. However, few studies have examined diet changes in recent decades. We analyzed dietary changes in Tianjin, China. The data in this descriptive, population-based study in ≥18-year-old adults were collecte...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu8020062
更新日期:2016-01-22 00:00:00
abstract::Information on the etiology of anemia is necessary to design effective anemia control programs. Our objective was to measure the prevalence of inherited hemoglobin disorders (IHD) in a representative sample of children in urban Cameroon, and examine the relationships between IHD and anemia. In a cluster survey of chil...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu9070693
更新日期:2017-07-03 00:00:00
abstract:BACKGROUND:Although Lactobacillus casei Shirota (LcS) can benefit the immune status, the effects of LcS in the immune/inflammatory responses of marathon runners has never been evaluated. Therefore, here we evaluated the effect of daily ingestion of fermented milk containing or not LcS in the systemic and upper airway i...
journal_title:Nutrients
pub_type: 临床试验,杂志文章
doi:10.3390/nu11071678
更新日期:2019-07-22 00:00:00
abstract::Diet may influence the risk of ischemic stroke by several mechanisms. A potential and hitherto unknown mechanism may relate to an effect on the lipophilic index, which is a new and convenient indicator of membrane fluidity. This study investigated the association between the adipose tissue lipophilic index and ischemi...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu10111570
更新日期:2018-10-23 00:00:00
abstract::The Eastern Mediterranean region is characterized by one of the highest burdens of paediatric obesity worldwide. This study aims at examining dietary, lifestyle, and socio-economic correlates of overweight, obesity, and abdominal adiposity amongst children and adolescents in Lebanon, a country of the Eastern Mediterra...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu6031038
更新日期:2014-03-10 00:00:00
abstract::Previous research indicated that preschoolers of lower socioeconomic status (SES) consume less healthy beverages than high SES preschoolers. The purpose of this study is to investigate the mediating role of parenting practices in the relationship between SES and plain water, soft drink and prepacked fruit juice (FJ) c...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu8100591
更新日期:2016-09-23 00:00:00
abstract::Obesity has recently risen and become a serious health concern in Korea according to the westernized diet and altered lifestyle. Hence, there is a growing interest in the supplementation of phytochemicals to find a safe and effective functional ingredient to treat obesity. Spergularia marina Griseb (SM) has traditiona...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12020336
更新日期:2020-01-27 00:00:00
abstract::How moderate white wine consumption modulates inflammatory cells infiltration of the ischemic myocardium following permanent coronary ligation was the key question addressed in this study. Male Sprague-Dawley rats were given either a combination of different white wines or water only for 28 days. Three peri-infarct/bo...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11081890
更新日期:2019-08-14 00:00:00
abstract::The novel coronavirus disease (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has engulfed the world, affecting more than 180 countries. As a result, there has been considerable economic distress globally and a significant loss of life. Sadly, the vulnerable and immunocomprom...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu12051466
更新日期:2020-05-19 00:00:00
abstract::Previous studies demonstrated that hyperglycemic glucose concentrations are observed in children that are overweight or have obesity. The aim of this study was to evaluate the effect of a 12 month lifestyle intervention on free-living glycemic profiles in children that were overweight or had obesity, and the associati...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12051228
更新日期:2020-04-26 00:00:00
abstract::Taste is influenced by several factors. However, whether habitual exercise level is associated with differences in taste perception has received little investigation. The aim of this study was to determine if habitual exercise is associated with differences in taste perception in men. Active (n = 16) and inactive (n =...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11010155
更新日期:2019-01-12 00:00:00
abstract:BACKGROUND:The CX3CL1-CX3CR1 axis has been related to numerous diseases. The aim of our study was to investigate its involvement in coeliac disease (CD) pathogenesis, particularly in the early phase of the disease. METHODS:We collected peripheral blood from CD patients and controls, enrolled in a 3-day gluten challeng...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11112551
更新日期:2019-10-23 00:00:00
abstract::Apolipoprotein E (APOE) and oxidative damage were correlated with the risk of Alzheimer's disease (AD). Glutathione S-transferase (GST) polymorphism was proved to be associated with body antioxidant capacity and involved in the oxidative damage related chronic diseases. To explore the combined effects of APOE rs429358...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu7105391
更新日期:2015-09-24 00:00:00
abstract::Poor vitamin D status has been associated with increased risk and severity of respiratory tract infections. Whether or not inflammation and infection affects 25-hydroxy vitamin D (25(OH)D) concentration is controversial and is important in the interpretation of observational studies using plasma-25(OH)D as a biomarker...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu9010052
更新日期:2017-01-17 00:00:00
abstract::The Mediterranean diet has demonstrated efficacy for improving cardiovascular and cognitive health. However, a traditional Mediterranean diet delivers fewer serves of dairy and less dietary calcium than is currently recommended in Australia, which may limit long-term sustainability. The present study aims to evaluate ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu9020145
更新日期:2017-02-16 00:00:00
abstract::Cherries are known for their nutraceutical properties, in particular for their antioxidant ability due to their polyphenol content, which causes a reduction of cardiovascular disease (CVD) risk factors. However, once ingested these molecules are degraded in the Gastrointestinal (GI) tract before reaching the blood, wh...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu10111598
更新日期:2018-11-01 00:00:00
abstract::We aimed to optimize calcium intake among the 2,000+ older women taking part in the Vital D study. Calcium supplementation was not included in the study protocol. Our hypothesis was that annual feedback of calcium intake and informing women of strategies to improve calcium intake can lead to a sustained increase in th...
journal_title:Nutrients
pub_type: 杂志文章,随机对照试验
doi:10.3390/nu20901018
更新日期:2010-09-01 00:00:00
abstract::As not much is known about the prevalence and predictors of nutritional deficiencies among vegans in the Czech Republic, we evaluated whether supplement use and duration of adherence to the vegan diet are associated with the risk of cobalamin and iron deficiencies. Associations between self-reported supplementation an...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11123019
更新日期:2019-12-10 00:00:00
abstract::Inula japonica Thunb. (Asteraceae) is a flowering plant that grows mainly in Korea, Japan, and China and its flower extract has diverse biological effects such as anti-inflammatory and antioxidative activities. However, the effects on obesity and enhancement of endurance capacity have not been explored yet. This study...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11010017
更新日期:2018-12-20 00:00:00
abstract::The aim of this review is to highlight current insights into the roles of choline and docosahexaenoic acid (DHA) in maternal and infant nutrition, with special emphasis on dietary recommendations, gaps in dietary intake, and synergistic implications of both nutrients in infant brain and eye development. Adequate choli...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu11051125
更新日期:2019-05-21 00:00:00
abstract::Hyperhomocysteinemia (HHcy) is a risk factor for atherosclerosis through mechanisms which are still incompletely defined. One possible mechanism involves the hypomethylation of the nuclear histone proteins to favor the progression of atherosclerosis. In previous cell studies, hypomethylating stress decreased a specifi...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12082182
更新日期:2020-07-23 00:00:00
abstract:BACKGROUND:There is still room for further studies aimed at investigating the most widespread diets in the Mediterranean area. The objective of the study is to analyze the relation of food group intake to clinical chemical indicators of health, and also to compare the food group intake with healthy well-known diet indi...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12103097
更新日期:2020-10-12 00:00:00
abstract::Plant proteins have become increasingly important for ecological reasons. Rapeseed is a novel source of plant proteins with high biological value, but its metabolic impact in humans is largely unknown. A randomized, controlled intervention study including 20 healthy subjects was conducted in a crossover design. All pa...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12082270
更新日期:2020-07-29 00:00:00
abstract::Colorectal cancer (CRC) is one of the most commonly occurring neoplasias in humans. The prevalence of CRC rates is still rising. Although the exact background of the disease still remains unknown, it is believed that CRC may not only be a result of environmental factors, but also genetic ones. One of the mechanisms un...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu13010200
更新日期:2021-01-11 00:00:00
abstract::The obesity epidemic has caused a widespread interest in strategies to achieve a healthy "high quality" weight loss, where excess fat is lost, while fat free mass (FFM) is preserved. In this study, we aimed to examine the effect of whey protein supplementation given before night sleep on FFM preservation during a 4-we...
journal_title:Nutrients
pub_type: 杂志文章,随机对照试验
doi:10.3390/nu10121918
更新日期:2018-12-04 00:00:00
abstract::In adults, fermentation of high amylose maize starch (HAMS), a resistant starch (RS), has a prebiotic effect. Were such a capacity to exist in infants, intake of RS might programme the gut microbiota during a critical developmental period. This study aimed to determine if infant faecal inocula possess the capacity to ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11061345
更新日期:2019-06-14 00:00:00