Abstract:
:Osteoporosis and associated low energy fractures are a significant clinical problem, especially in the elderly population. The occurrence of a hip fracture is associated with significant mortality and a high risk of disability. For this, apart from the treatment of osteoporosis, effective prevention of both the development of the disease and related fractures is extremely important. One aspect of osteoporosis prevention is proper dietary calcium intake and normal vitamin D3 levels. However, there is some evidence for a potential role of vitamin C in osteoporosis and fracture prevention, too. This review aims to summarize the current knowledge about the role of vitamin C in osteoporosis development, prevention and treatment. The PubMed/Medline search on the role of vitamin C in bone metabolism database was performed for articles between 2000 and May 2020. Reports from in vitro and animal studies seem promising. Epidemiological studies also indicate the positive effect of high vitamin C content in the daily diet on bone mineral density. Despite promising observations, there are still few observational and intervention studies and their results do not allow for unequivocal determination of the benefits of high daily intake of vitamin C or its long-term supplementation.
journal_name
Nutrientsjournal_title
Nutrientsauthors
Brzezińska O,Łukasik Z,Makowska J,Walczak Kdoi
10.3390/nu12082394subject
Has Abstractpub_date
2020-08-10 00:00:00issue
8issn
2072-6643pii
nu12082394journal_volume
12pub_type
杂志文章,评审相关文献
Nutrients文献大全abstract::Little evidence is available regarding the relationship between zinc and sleep in school children. The present study aimed to examine the cross-sectional and longitudinal associations between blood zinc concentrations and sleep quality throughout childhood. A total of 1295 children from the Jintan Child Cohort in Chin...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu7075247
更新日期:2015-07-13 00:00:00
abstract::Children's eating behavior does not necessarily align with dietary recommendations, and there is a need for better understanding the factors underlying their food choices. The aim of this study was to investigate children's self-reported reasons for accepting and rejecting foods. A questionnaire was developed with rea...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11102455
更新日期:2019-10-14 00:00:00
abstract::Apolipoprotein E (ApoE) is a protein playing a pivotal role in lipid homeostasis since it regulates cholesterol, triglyceride and phospholipid metabolism in the blood and the brain. APOE gene regulates the expression of this protein and has three different alleles: ε2, ε3 and ε4. Carrying an APOE4 allele is recognised...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu6104452
更新日期:2014-10-20 00:00:00
abstract::Vitamin D status was assessed in a large urban area to compare differences in deficiency and to geomap the results. In total, 36,466 participants from 28 geographical areas were identified in this cross-sectional, retrospective analysis of general practitioner (GP)-requested 25(OH)D tests at St James's Hospital, Dubli...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12092663
更新日期:2020-08-31 00:00:00
abstract::Taste is influenced by several factors. However, whether habitual exercise level is associated with differences in taste perception has received little investigation. The aim of this study was to determine if habitual exercise is associated with differences in taste perception in men. Active (n = 16) and inactive (n =...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11010155
更新日期:2019-01-12 00:00:00
abstract::Diet may influence the risk of ischemic stroke by several mechanisms. A potential and hitherto unknown mechanism may relate to an effect on the lipophilic index, which is a new and convenient indicator of membrane fluidity. This study investigated the association between the adipose tissue lipophilic index and ischemi...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu10111570
更新日期:2018-10-23 00:00:00
abstract::(1) Background: The etiology of non-alcoholic fatty liver disease (NAFLD) is multifactorial. Dietary composition has been implicated as a factor modulating intestinal barrier and could affect disease severity. The aim of this study was to evaluate dietary intake and markers of intestinal permeability in patients with ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12030699
更新日期:2020-03-05 00:00:00
abstract::Nowadays, scientific studies are emerging on the possible etiological role of intestinal parasites in functional digestive disorders. Our study was carried out with healthy individuals (control group; n = 82) and symptomatic patients with lactose or fructose malabsorption, including positive (malabsorbers; n = 213) an...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11122973
更新日期:2019-12-05 00:00:00
abstract:BACKGROUND:Pediatric eating disorders (PED) patients are prone to nutritional deficiencies. Thiamine deficiency is well described in other malnutrition states but is not routinely screened for in PED. In the current study we evaluated the prevalence of thiamine deficiency among PED patients on their first admission to ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12051396
更新日期:2020-05-13 00:00:00
abstract::Colorectal cancer affects the large intestine, leading to loss of white adipose tissue (WAT) and alterations in adipokine secretion. Lower incidence of colorectal cancer is associated with increased fibre intake. Fructooligosaccharides (FOS) are fibres that increase production of butyrate by the intestinal microbiota....
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11010110
更新日期:2019-01-08 00:00:00
abstract::The AUSNUT 2011-13 food composition database was expanded to include Australian choline values. The development began with a systematic literature review of published studies. Analytical data from the food studies were extracted and aligned with their equivalent AUSNUT food identification code. Global food composition...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11040913
更新日期:2019-04-23 00:00:00
abstract::Kynurenic acid, a metabolite of the kynurenine pathway of tryptophan catabolism, acts as an antagonist for both the α7 nicotinic acetylcholine receptor and glycine coagonist sites of the N-methyl-d-aspartic acid receptor at endogenous brain concentrations. Elevation of brain kynurenic acid levels reduces the release o...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu12051403
更新日期:2020-05-13 00:00:00
abstract::Advanced glycation endproducts (AGEs) can be found in protein- and sugar-rich food products processed at high temperatures, which make up a vast amount of the Western diet. The effect of AGE-rich food products on human health is not yet clear and controversy still exists due to possible contamination of samples with e...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu10121868
更新日期:2018-12-02 00:00:00
abstract::In this study, we investigated the beneficial effects of milk biofortified with antioxidants on the health of children. Two experiments were conducted: experiment one evaluated the milk of 24 Jersey dairy cows (450 ± 25 kg of body weight (BW); 60 ± 30 days in milk dry matter intake (DIM)) given different diet treatmen...
journal_title:Nutrients
pub_type: 杂志文章,随机对照试验
doi:10.3390/nu11061218
更新日期:2019-05-29 00:00:00
abstract::The response to resistance training and protein supplementation in the latissimus dorsi muscle (LDM) has never been investigated. We investigated the effects of resistance training (RT) and protein supplementation on muscle mass, strength, and fiber characteristics of the LDM. Eighteen healthy young subjects were rand...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu8060331
更新日期:2016-06-01 00:00:00
abstract::Oligosaccharides (OS) are commonly added to infant formulas, however, their physiological impact, particularly on adult health programming, is poorly described. In adult animals, OS modify microbiota and stimulate colonic fermentation and enteroendocrine cell (EEC) activity. Since neonatal changes in microbiota and/or...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11091967
更新日期:2019-08-21 00:00:00
abstract::Socio-economic status (SES) has an impact on food consumption in developing countries. However, the impact of SES on dietary patterns in Filipino school-aged children is currently unknown. The aim of this study was to fill this knowledge gap, using data from the 2013 National Nutrition Survey. Dietary intake of 11,691...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11122910
更新日期:2019-12-02 00:00:00
abstract::Cancer is the main cause of mortality and morbidity worldwide. Although a large variety of therapeutic approaches have been developed and translated into clinical protocols, the toxic side effects of cancer treatments negatively impact patients, allowing cancer to grow. Brassica metabolites are emerging as new weapons...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu12030868
更新日期:2020-03-24 00:00:00
abstract::Anthracycline anticancer drugs, such as doxorubicin (DOX), can induce cardiotoxicity supposed to be related to mitochondrial damage. We have recently demonstrated that a branched-chain amino acid (BCAA)-enriched mixture (BCAAem), supplemented with drinking water to middle-aged mice, was able to promote mitochondrial b...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12020282
更新日期:2020-01-21 00:00:00
abstract::Dietary protein sources have profound effects on children and young animals, and are important for the gut barrier function and immune resilience. Milk and soy are the main sources of protein for children and young animals after weaning. The objective of this study was to compare the effects of dairy and soy proteins ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12092739
更新日期:2020-09-08 00:00:00
abstract::There are a significant number of studies on cognitive restraint among individuals with varying dietary patterns. Although most research has found that vegetarians report higher levels of cognitive restraint compared to non-vegetarians, many studies have contributed inconsistent results. The aim of the current study, ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12072133
更新日期:2020-07-17 00:00:00
abstract::Quercetin, a medicinally important member of the flavonoid family, is one of the most prominent dietary antioxidants. It is present in a variety of foods-including fruits, vegetables, tea, wine, as well as other dietary supplements-and is responsible for various health benefits. Numerous pharmacological effects of que...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu8090529
更新日期:2016-08-29 00:00:00
abstract::The intestinal microbiome plays an important role in maintaining health throughout life. The microbiota develops progressively after birth and is influenced by many factors, including the mode of delivery, antibiotics, and diet. Maternal milk is critically important to the development of the neonatal intestinal microb...
journal_title:Nutrients
pub_type: 杂志文章,评审
doi:10.3390/nu12030823
更新日期:2020-03-20 00:00:00
abstract:OBJECTIVE:To investigate dietary habits, sleep and psychological well-being of adolescents and medical students during COVID-19 lockdown in Split, Croatia. METHODS:We surveyed 1326 students during 2018 and 2019, and compared their responses with 531 students enrolled in May 2020. Perceived stress, quality of life (QoL...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu13010097
更新日期:2020-12-30 00:00:00
abstract::Adequate calorie restriction (CR) as a healthy lifestyle is recommended not only for people with metabolic disorders but also for healthy adults. Previous studies have mainly focused on the beneficial metabolic effects of CR on obese subjects, while its effects on non-obese subjects are still scarce. Here, we conducte...
journal_title:Nutrients
pub_type: 临床试验,杂志文章
doi:10.3390/nu12030631
更新日期:2020-02-27 00:00:00
abstract::We appreciate the interest of Dr [...]. ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu12072093
更新日期:2020-07-15 00:00:00
abstract::A high intake of refined carbohydrates, particularly the monosaccharide fructose, has been attributed to the growing epidemics of obesity and type-2 diabetes. Animal studies have helped elucidate the metabolic effects of dietary fructose, however, variations in study design make it difficult to draw conclusions. The a...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu8090577
更新日期:2016-09-20 00:00:00
abstract::The aim of this systematic review is to assess whether metformin could change the concentration of serum homocysteine (Hcy) with and without simultaneous supplementation of B-group vitamins or folic acid. A literature search was conducted in PubMed, EmBase, and Cochrane Central Register of Controlled Trials (CENTRAL) ...
journal_title:Nutrients
pub_type: 杂志文章,meta分析,评审
doi:10.3390/nu8120798
更新日期:2016-12-09 00:00:00
abstract::Selenium is an essential trace element which is incorporated in the form of a rare amino acid, the selenocysteine, into an important group of proteins, the selenoproteins. Among the twenty-five selenoprotein genes identified to date, several have important cellular functions in antioxidant defense, cell signaling and ...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11071524
更新日期:2019-07-04 00:00:00
abstract::The number of patients with mental illnesses is rapidly increasing, and daily lifestyle is closely associated with the development of symptoms. It is suggested that inflammatory molecules derived from microglia play crucial roles for the pathophysiology of depression. In the present study, we discovered that leucine-h...
journal_title:Nutrients
pub_type: 杂志文章
doi:10.3390/nu11092161
更新日期:2019-09-09 00:00:00