Abstract：
:High sugar intake in childhood has been linked to obesity. However, the role of macronutrient substitutions and associations with metabolic health remain unclear. We examined associations of carbohydrate intake and its subtypes with body composition and metabolic health among 3573 children participating in a population-based cohort in the Netherlands. Intake of total carbohydrate, monosaccharides and disaccharides, and polysaccharides at age 1 year was assessed with a food-frequency questionnaire. We repeatedly measured children's height and weight to calculate BMI between their ages of 1 and 10 years. At ages 6 and 10 years, fat and fat-free mass were measured with dual-energy X-ray-absorptiometry and blood concentrations of triglycerides, cholesterol, and insulin were obtained. For all outcomes, we calculated age and sexspecific SD-scores. In multivariable-adjusted linear mixed models, we found no associations of intake of carbohydrates or its subtypes with children's BMI or body composition. A higher intake of monosaccharides and disaccharides was associated with higher triglyceride concentrations (0.02 SDS per 10 g/d, 95% CI: 0.01, 0.04). Higher monosaccharide and disaccharide intake was also associated with lower HDL-cholesterol (-0.03 SDS, 95% CI: -0.04; -0.01), especially when it replaced polysaccharides. Overall, our findings suggest associations of higher monosaccharide and disaccharide intake in early childhood with higher triglyceride and lower HDL-cholesterol concentrations, but do not support associations with body composition.
journal_name
Nutrientsjournal_title
Nutrientsauthors
Nguyen AN,Santos S,Braun KVE,Voortman Tdoi
10.3390/nu12071940subject
Has Abstractpub_date
2020-06-30 00:00:00issue
7issn
2072-6643pii
nu12071940journal_volume
12pub_type
杂志文章相关文献
Nutrients文献大全abstract：:Obese premenopausal women with breast cancer have poorer prognosis for long term survival, in part because their tumors are larger at the time of diagnosis than are found in normal weight women. Whether larger tumor mass is due to obesity-related barriers to detection or to effects on tumor biology is not known. This ...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu8040214
更新日期：2016-04-11 00:00:00
abstract：:The aim of this study was a large-scale ecological analysis of nutritional and other environmental factors potentially associated with the incidence of cardiovascular diseases (CVDs) in the global context. Indicators of CVDs from 158 countries were compared with the statistics of mean intake (supply) of 60 food items ...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu10040411
更新日期：2018-03-26 00:00:00
abstract：:The population of older adults is growing globally. This increase has led to an accumulation of chronic illnesses, so-called age-related diseases. Diet and nutrition are considered the main drivers of the global burden of diseases, and this situation applies especially to this population segment. It relates directly t...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu11061275
更新日期：2019-06-05 00:00:00
abstract：:One-anastomosis gastric bypass is a promising type of bariatric surgery, but it may lead to a deficiency in important nutrients, such as fatty acids. The short-term effects of one-anastomosis gastric bypass on serum fatty acids have not been studied thus far. Therefore, the aim of this study was to determine the effec...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12010187
更新日期：2020-01-09 00:00:00
abstract：:γ-Oryzanol (OZ), abundant in rice bran oil, has gained attention due to its physiological activities (e.g., lipid-lowering effects). However, the absorption and metabolism of orally ingested OZ have not yet been fully elucidated. In this study, diets containing normal or high contents of OZ were fed to obesity model m...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu11010104
更新日期：2019-01-06 00:00:00
abstract：:Vascular disease poses a major public health problem worldwide. Trigonelline isolated from Raphanus sativus cv. Sakurajima Daikon (Sakurajima radish) induces nitric oxide production from vascular endothelial cells and enhances vascular function. Here, we investigated the characteristics of trigonelline and its effects...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12061872
更新日期：2020-06-23 00:00:00
abstract：:The rising prevalence of overweight and obesity is a global concern, increasing the risk of numerous non-communicable diseases and reducing quality of life. A healthy diet and exercise remain the cornerstone treatments for obesity. However, adherence rates can be low and the effectiveness of these interventions is oft...
journal_title：Nutrients
pub_type： 杂志文章,评审
doi：10.3390/nu12051398
更新日期：2020-05-13 00:00:00
abstract：:Obesity and weight gain in bipolar disorder (BD) have multifactorial underlying causes such as medication side effects, atypical depressive symptomatology, genetic variants, and disturbances in the neuro-endocrinal system. Therefore, we aim to explore the associations between food craving (FC), clinical parameters, ps...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu13010076
更新日期：2020-12-29 00:00:00
abstract：:Several studies have linked increased intake of dietary fibre to improvement in the management of body weight. Dietary fibre from resistant starch (RS) has been shown to have an impact on food intake in normal weight individuals, but its role in obesity is unknown. The present study aimed to investigate the short-term...
journal_title：Nutrients
pub_type： 杂志文章,随机对照试验
doi：10.3390/nu10121993
更新日期：2018-12-15 00:00:00
abstract：:Type 2 diabetes mellitus (T2DM) is associated with increased total plasma free fatty acid (FFA) concentrations and an elevated risk of cardiovascular disease. The exact mechanisms by which the plasma FFA profile of subjects with T2DM changes is unclear, but it is thought that dietary fats and changes to lipid metaboli...
journal_title：Nutrients
pub_type： 杂志文章,评审
doi：10.3390/nu11092022
更新日期：2019-08-28 00:00:00
abstract：:The joint symposium of The Omega-3 Centre and the Australasian Section American Oil Chemists Society; Recent Advances in Omega-3: Health Benefits, Sources, Products and Bioavailability, was held November 7, 2013 in Newcastle, NSW, Australia. Over 115 attendees received new information on a range of health benefits, aq...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu6093727
更新日期：2014-09-16 00:00:00
abstract：:Age-related macular degeneration and retinitis pigmentosa are leading causes of blindness and share a pathological feature, which is photoreceptor degeneration. To date, the lack of a potential treatment to prevent such diseases has raised great concern. Photoreceptor degeneration can be accelerated by excessive light...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu10121991
更新日期：2018-12-15 00:00:00
abstract：:Efforts to shape the food environment are aimed at reducing diet-related co-morbidities. Front-of-package labeling (FOPL) may support the consumers to make an informed decision at the point of purchase and encourage industry to reformulate food products. The Israeli Ministry of Health (MOH) implemented a unique FOPL s...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12061875
更新日期：2020-06-23 00:00:00
abstract：:Due to the functional properties and physiological effects often associated with chemically modified starches, significant interest lies in their development for incorporation in processed foods. This study investigated the effect of transglycosylated cornstarch (TGS) on blood glucose, insulin, and serum metabolome in...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu9030291
更新日期：2017-03-16 00:00:00
abstract：:Children born from mothers with gestational diabetes mellitus (GDM) are at high-risk of obesity and type 2 diabetes. To date, there is a lack of effective strategies to prevent these complications. The aim of this study was to evaluate the association between diet quality and anthropometric and glycemic profiles of ch...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu11030570
更新日期：2019-03-07 00:00:00
abstract：:Athletes competing in ultra-endurance sports should manage nutritional issues, especially with regards to energy and fluid balance. An ultra-endurance race, considered a duration of at least 6 h, might induce the energy balance (i.e., energy deficit) in levels that could reach up to ~7000 kcal per day. Such a negative...
journal_title：Nutrients
pub_type： 杂志文章,评审
doi：10.3390/nu10121995
更新日期：2018-12-16 00:00:00
abstract：:The role of vitamin D in obesity appears to be linked to vitamin D insufficient/deficient status. However, mechanistic understanding of the role of vitamin D in obesity is lacking. We have shown earlier that the vitamin D hormonal form, 1,25-dihydroxyvitamin D3 (1,25(OH)2D3), induces cell death by apoptosis in mature ...
journal_title：Nutrients
pub_type： 杂志文章,评审
doi：10.3390/nu12051392
更新日期：2020-05-13 00:00:00
abstract：:The brain is an important modulator of glucose metabolism, and is known to respond Gastrodia elata Blume water extract (GEB). Therefore, we examined whether long-term administration of GEB has hypoglycemic activity, and its action mechanism was explored in partially-pancreatectomized rats that exhibit similar characte...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu8030161
更新日期：2016-03-11 00:00:00
abstract：:Impulsivity, particularly towards food, is a potential risk factor for increased energy intake and the development and maintenance of obesity in children. However, neuropsychological and neurophysiological indicators of general and food-specific impulsivity and their association with children's weight status are poorl...
journal_title：Nutrients
pub_type： 临床试验,杂志文章
doi：10.3390/nu10121983
更新日期：2018-12-15 00:00:00
abstract：:Chile has implemented several strategies to decrease the burden of obesity and chronic diseases. The Food Labeling and Advertising Law (Law 20.606) requires a front-of-package "high in" warning label when energy and nutrients of concern (ENC) (total sugar, saturated fats, sodium) exceed established limits. This study ...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12082371
更新日期：2020-08-08 00:00:00
abstract：:4-Hydroxy-3-methoxycinnamic acid (HMCA), a hydroxycinnamic acid derivative, is abundant in fruits and vegetables, including oranges, carrots, rice bran, and coffee beans. Several beneficial effects of HMCA have been reported, including improvement of metabolic abnormalities in animal models and human studies. However,...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu11051036
更新日期：2019-05-09 00:00:00
abstract：BACKGROUND:The CX3CL1-CX3CR1 axis has been related to numerous diseases. The aim of our study was to investigate its involvement in coeliac disease (CD) pathogenesis, particularly in the early phase of the disease. METHODS:We collected peripheral blood from CD patients and controls, enrolled in a 3-day gluten challeng...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu11112551
更新日期：2019-10-23 00:00:00
abstract：:Calendula officinalis, Ribes nigrum, and Vaccinium myrtillus (CRV) possess a high phenolic compound content with excellent antioxidant activity. Dietary antioxidants can reduce exercise-induced oxidative stress. Consumption of large amounts of phenolic compounds is positively correlated with reduction in exercise-indu...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu11081715
更新日期：2019-07-25 00:00:00
abstract：:Early meal timing and chronotype are associated with lower BMI, but their impact on appetite is poorly understood. We examined the impact of meal timing and chronotype on appetite and food reward. Forty-four adults were divided into early (EC; Morningness-Eveningness Questionnaire (MEQ) score = 55 ± 5) or late chronot...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12051506
更新日期：2020-05-22 00:00:00
abstract：:Vegetarian diets have gained popularity in sports. However, few data exist on the status of micronutrients and related biomarkers for vegetarian and vegan athletes. The aim of this cross-sectional study was to compare the micronutrient status of omnivorous (OMN, n = 27), lacto-ovo-vegetarian (LOV, n = 26), and vegan (...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu11051146
更新日期：2019-05-22 00:00:00
abstract：:(1) Introduction: Current evidence on managing infants under six months with growth failure or other nutrition-related risk is sparse and low quality. This review aims to inform research priorities to fill this evidence gap, focusing on breastfeeding practices. (2) Methods: We searched PubMed, CINAHL Plus, and Cochran...
journal_title：Nutrients
pub_type： 杂志文章,评审
doi：10.3390/nu12072044
更新日期：2020-07-09 00:00:00
abstract：:Reducing salt intake is a cost-effective public health intervention to reduce the global burden of non-communicable disease (NCDs). Ultra-processed foods contribute ~80% of dietary salt in high income countries, and are becoming prominent in low-middle income countries. Instant noodle consumption is particularly high ...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu9060612
更新日期：2017-06-16 00:00:00
abstract：:Many infant formulas are fortified with iron at 8-14 mg/L whereas breast milk contains about 0.3 mg/L. Another major difference between breast milk and infant formula is its high concentration of lactoferrin, a bioactive iron-binding protein. The aim of the present study was to investigate how reducing the iron conten...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu13010003
更新日期：2020-12-22 00:00:00
abstract：:Severe acute respiratory syndrome coronavirus type (SARS-CoV2, also known as COVID-19), which is the latest pandemic infectious disease, constitutes a serious risk to human health. SARS-CoV2 infection causes immune activation and systemic hyperinflammation which can lead to respiratory distress syndrome (ARDS). ARDS v...
journal_title：Nutrients
pub_type： 杂志文章,评审
doi：10.3390/nu12113512
更新日期：2020-11-14 00:00:00
abstract：:Isoflavones, phytoestrogens in soy beans with estrogen-like properties, have been examined for their cancer protective effects. Mammographic density is a strong predictor of breast cancer. This review summarizes studies that have examined the association between isoflavones and breast density. Observational investigat...
journal_title：Nutrients
pub_type： 杂志文章,评审
doi：10.3390/nu2010035
更新日期：2010-01-01 00:00:00
