Abstract：
:Calendula officinalis, Ribes nigrum, and Vaccinium myrtillus (CRV) possess a high phenolic compound content with excellent antioxidant activity. Dietary antioxidants can reduce exercise-induced oxidative stress. Consumption of large amounts of phenolic compounds is positively correlated with reduction in exercise-induced muscle damage. Research for natural products to improve exercise capacity, relieve fatigue, and accelerate fatigue alleviation is ongoing. Here, CRV containing a large total phenolic content (13.4 mg/g of CRV) demonstrated antioxidant activity. Ultra-performance liquid chromatography quantification revealed 1.95 ± 0.02 mg of salidroside in 1 g of CRV. In the current study, CRV were administered to mice for five weeks, and the antifatigue effect of CRV was evaluated using the forelimb grip strength test; weight-loaded swimming test; and measurement of fatigue-related biochemical indicators, such as blood lactate, ammonia, glucose, blood urea nitrogen (BUN), and creatine kinase (CK) activity; and muscle and liver glycogen content. The results indicated that in CRV-treated mice, the forelimb grip strength significantly increased; weight-loaded swimming time prolonged; their lactate, ammonia, BUN, and CK activity decreased, and muscle and liver glucose and glycogen content increased compared with the vehicle group. Thus, CRV have antifatigue activity and can increase exercise tolerance.
journal_name
Nutrientsjournal_title
Nutrientsauthors
Tung YT,Wu MF,Lee MC,Wu JH,Huang CC,Huang WCdoi
10.3390/nu11081715subject
Has Abstractpub_date
2019-07-25 00:00:00issue
8issn
2072-6643pii
nu11081715journal_volume
11pub_type
杂志文章相关文献
Nutrients文献大全abstract：:Flavonols and flavanones are polyphenols exerting many healthy biological activities. They are often glycosylated by rutinose, which hampers absorption in the small intestine. Therefore they require the gut microbiota to release the aglycone and enable colonic absorption. The role of the gut microbiota and bifidobacte...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu7042788
更新日期：2015-04-14 00:00:00
abstract：:A dynamic human gastrointestinal (GI) model was used to digest cooked tubers from purple-fleshed Amachi and Leona potato cultivars to study anthocyanin biotransformation in the stomach, small intestine and colonic vessels. Colonic Caco-2 cancer cells and non-tumorigenic colonic CCD-112CoN cells were tested for cytotox...
journal_title：Nutrients
pub_type： 临床试验,杂志文章
doi：10.3390/nu9090953
更新日期：2017-08-29 00:00:00
abstract：:Polyphenols are found ubiquitously in plants and their regular consumption has been associated with a reduced risk of a number of chronic diseases, including cancer, cardiovascular disease (CVD) and neurodegenerative disorders. Rather than exerting direct antioxidant effects, the mechanisms by which polyphenols expres...
journal_title：Nutrients
pub_type： 杂志文章,评审
doi：10.3390/nu2111106
更新日期：2010-11-01 00:00:00
abstract：:Current dietary patterns are negatively affecting both the environment and people's health. Healthy diets are generally more environmentally friendly. However, few studies have focused on the health consequences of diets with low environmental impact. We analyzed differences in the dietary composition (types of food, ...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12082385
更新日期：2020-08-09 00:00:00
abstract：:Dietary n-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are associated with reduction of inflammation, although the mechanisms are poorly understood, especially how the spleen, as a secondary lymphoid organ, is involved. To investigate the effects of EPA and DHA on spleen gene expression, ma...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu9010050
更新日期：2017-01-10 00:00:00
abstract：:Few evaluations of interventions to delay or prevent type 2 diabetes mellitus (T2DM) in Saudi Arabia (SA) have been undertaken. The present study evaluates the impact of a 6-month intensive lifestyle modification intervention delivered in primary care. Females from SA with prediabetes, aged 18-55 years, were recruited...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu11051113
更新日期：2019-05-18 00:00:00
abstract：:Allium genus plants, such as leek (Allium porrum), are rich sources of anti-inflammatory and anti-oxidant secondary metabolites; this is of interest because it demonstrates their suitability as pharmacological alternatives for inflammatory processes, including allergy treatment. The composition of methanolic leek extr...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu11061303
更新日期：2019-06-08 00:00:00
abstract：:A growing body of evidence supports a role for tissue-to-diet 15N and 13C discrimination factors (Δ15N and Δ13C), as biomarkers of metabolic adaptations to nutritional stress, but the underlying mechanisms remain poorly understood. In obese rats fed ad libitum or subjected to gradual caloric restriction (CR), under a ...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu11051087
更新日期：2019-05-16 00:00:00
abstract：:Statins and omega-3 supplementation have shown potential benefits in preventing cardiovascular disease (CVD), but their comparative effects on mortality outcomes, in addition to primary and secondary prevention and mixed population, have not been investigated. This study aimed to examine the effect of statins and omeg...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12103203
更新日期：2020-10-20 00:00:00
abstract：BACKGROUND:Numerous scientific studies on patients with autism spectrum disorder (ASD) suggest a significant role of inflammation processes or lipid disorders in this spectrum of neurodevelopmental disorders. Unfortunately, there is a lack of assessments of changes over time regarding level of lipids and inflammatory m...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12092594
更新日期：2020-08-26 00:00:00
abstract：:Obesity is not the same in all individuals and two different phenotypes have been described: metabolically healthy obesity (MHO) and metabolically unhealthy obesity (MUO). The aim of this study was to identify factors that explain metabolic health status in a rigorously matched Spanish population. Subcutaneous and vis...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu13010119
更新日期：2020-12-31 00:00:00
abstract：:Skin is a major safeguard tissue in humans. Because biological barrier function is deteriorated by several kinds of stresses including exposure to ultra-violet (UV) rays, the protection and treatment of skin conditions by dietary supplements are important. We therefore evaluated the effects of dietary supplementation ...
journal_title：Nutrients
pub_type： 杂志文章,随机对照试验
doi：10.3390/nu10070817
更新日期：2018-06-25 00:00:00
abstract：:The imbalance of gut microbiota is known to be associated with inflammatory bowel disease, but it remains unknown whether dysbiosis is a cause or consequence of chronic gut inflammation. In order to investigate the effects of gut inflammation on microbiota and metabolome, the sequential changes in gut microbiota and m...
journal_title：Nutrients
pub_type： 杂志文章,meta分析
doi：10.3390/nu9121329
更新日期：2017-12-06 00:00:00
abstract：:The relationship between the Dietary Approaches to Stop Hypertension (DASH) diet and metabolic syndrome (MetS) in people with schizophrenia is unknown and remains to be investigated. Therefore, we have conducted a three-month parallel-group randomized controlled trial. Sixty-seven hospitalized schizophrenic patients w...
journal_title：Nutrients
pub_type： 杂志文章,随机对照试验
doi：10.3390/nu11122950
更新日期：2019-12-04 00:00:00
abstract：:The physical and biochemical changes resulting from moderately low magnesium (Mg) intake are not fully understood. Obesity and associated co-morbidities affect Mg metabolism and may exacerbate Mg deficiency and physiological effects. Male rats selectively bred for diet-induced obesity (OP, obese-prone) or resistance (...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu8050253
更新日期：2016-04-28 00:00:00
abstract：:Gut appetite hormone responses may be influenced by meal macronutrients and obesity. The primary aim of this study was to examine in adolescents with obesity and of healthy weight the effect of a high-protein and a high-carbohydrate meal on postprandial gut appetite hormones. A postprandial cross-over study with adole...
journal_title：Nutrients
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.3390/nu11020340
更新日期：2019-02-05 00:00:00
abstract：:Melanoidins are the final Maillard reaction products (protein-carbohydrate complexes) produced in food by prolonged and intense heating. We assessed the impact of the consumption of melanoidins from barley malts on gut microbiota. Seventy-five mice were assigned into five groups, where the control group consumed a non...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12010241
更新日期：2020-01-17 00:00:00
abstract：:β-hydroxybutyrate (β-OHB) has been shown to exert an anti-inflammatory activity. Apolipoprotein-E (ApoE) is strongly associated with atherosclerosis and Alzheimer's disease (AD). This study aimed to explore the therapeutic effect of β-OHB in the brain and the aorta of high-fat diet (HFD)-fed ApoE-deficient mice. We fo...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12020471
更新日期：2020-02-13 00:00:00
abstract：:Chile has implemented several strategies to decrease the burden of obesity and chronic diseases. The Food Labeling and Advertising Law (Law 20.606) requires a front-of-package "high in" warning label when energy and nutrients of concern (ENC) (total sugar, saturated fats, sodium) exceed established limits. This study ...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12082371
更新日期：2020-08-08 00:00:00
abstract：:The bile acid receptor, TGR5, is a key regulator of glucose homeostasis, but the mechanisms by which TGR5 signaling improves glucose regulation are incompletely defined. In particular, TGR5 has an increasingly appreciated role in liver physiology and pathobiology; however, whether TGR5 signaling within the liver contr...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12072124
更新日期：2020-07-17 00:00:00
abstract：BACKGROUND:The success of Helicobacter pylori (H. pylori) eradication depends on several host and treatment factors. Serum vitamin D levels may be associated with H. pylori infection and eradication rates. We investigated the association between vitamin D and H. pylori infection and eradication, using a large electroni...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu13010278
更新日期：2021-01-19 00:00:00
abstract：:Polycystic ovarian syndrome (PCOS) is an endocrine, metabolic, and systemic disease. It is mainly characterized by hyperandrogenism, oligomenorrhea, and high levels of luteinizing hormone (LH). There is no obvious therapy for PCOS, so patients have received symptomatic therapy. Welsh onion (Allium fistulosum) is well-...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu10101430
更新日期：2018-10-04 00:00:00
abstract：:Egg-yolk based supplements have demonstrated biological effects. We have developed a novel processed egg-yolk (PEY) complement, and we have tested whether it has inflammation modulatory properties. These were evaluated in a lipopolysaccharide (LPS)-challenge in 1-month male rats by in vivo circulating cytokine profile...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12092699
更新日期：2020-09-04 00:00:00
abstract：:The polyphenol resveratrol (RVT) may drive protective mechanisms of cerebral homeostasis during the hypoperfusion/reperfusion triggered by the transient bilateral common carotid artery occlusion followed by reperfusion (BCCAO/R). This immunochemical study investigates if a single dose of RVT modulates the plasticity-r...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu11051000
更新日期：2019-05-01 00:00:00
abstract：BACKGROUND:prediabetes prevention and management are the main methods used to combat the prevalence of diabetes. Exploratory factor analysis is an upcoming method that is successful in identifying dietary patterns that correlate with healthy or unhealthy outcomes. AIM:this study aims to identify dietary patterns in Ta...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12113322
更新日期：2020-10-29 00:00:00
abstract：:To reduce the sugar content of processed foods through reformulation, the first step is to determine the content of the largest sources of sugars in each country's diet. The aim of this work was to describe the sugar content in the most commonly consumed processed foods in Spain and to compare that sugar's labelling a...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu12041078
更新日期：2020-04-13 00:00:00
abstract：:We studied trends in fish intake among pregnant women living in the Madeira River Basin in Rondônia State, Brazil, to investigate the influence of maternal fish intake on anthropometric indices of children followed up to 5 years. Maternal fish intake was assessed using hair mercury concentrations of mothers and childr...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu10091146
更新日期：2018-08-23 00:00:00
abstract：:Hedychium coronarium has a long history of use worldwide as a food and in folk medicine. In this study, we aimed to investigate the effect of an aqueous extract of H. coronarium leaves (HC) on type 2 diabetes mellitus (T2DM). Two types of animal models were used in this study: Streptozotocin (STZ)-induced T2DM (Wistar...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu11030629
更新日期：2019-03-14 00:00:00
abstract：:Since 1998, the U.S. has mandated folic acid (FA) fortification of certain grain products to reduce the risk of neural tube defects. Folate intake and red blood cell (RBC) folate concentrations increased substantially post-intervention, although recent studies raise concerns about the level of ongoing benefit. This st...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu9090994
更新日期：2017-09-08 00:00:00
abstract：:Essential amino acids (EAA) consist of a group of nine amino acids that animals are unable to synthesize via de novo pathways. Recently, it has been found that most metazoans lack the same set of enzymes responsible for the de novo EAA biosynthesis. Here we investigate the sequence conservation and evolution of all th...
journal_title：Nutrients
pub_type： 杂志文章
doi：10.3390/nu7010001
更新日期：2014-12-24 00:00:00
