Efficacy of acupuncture and electroacupuncture in patients with nonspecific low back pain: study protocol for a randomized controlled trial.

abstract：OBJECTIVES:Primary Objective • To assess the efficacy of herbal extracts in boosting innate immunity of patients with COVID-19 infection. Secondary Objectives • To assess the efficacy of herbal extracts in restoring respiratory health • To assess the efficacy of Cap. IP in early recovery of patients and decline in vira...

journal_title：Trials

authors： Rangnekar H,Patankar S,Suryawanshi K,Soni P

更新日期：2020-11-23 00:00:00

abstract：BACKGROUND:The serious mental illness Health Improvement Profile [HIP] is a brief pragmatic tool, which enables mental health nurses to work together with patients to screen physical health and take evidence-based action when variables are identified to be at risk. Piloting has demonstrated clinical utility and accepta...

journal_title：Trials

authors： White J,Gray RJ,Swift L,Barton GR,Jones M

更新日期：2011-07-04 00:00:00

abstract：BACKGROUND:Basal cell carcinoma is the most common skin cancer worldwide. Treatment options include both surgical and topical modalities. Although risk of metastasis is low, basal cell carcinoma can be invasive and infiltrate important underlying structures such as bone or cartilage. While many clinical trials examinin...

journal_title：Trials

authors： Schlessinger DI,Iyengar S,Yanes AF,Lazaroff JM,Godinez-Puig V,Chen BR,Kurta AO,Henley JK,Chiren SG,Furlan KC,Schmitt J,Deckert S,Poon E,Sobanko JF,Cartee TV,Alam M,Maher IA

更新日期：2017-10-23 00:00:00

abstract：:Mental health problems are highly prevalent in children and adolescents, but professional help-seeking behavior in this age group is extremely low. Therefore, the ProHEAD ("Promoting Help-seeking using E-technology for Adolescents") consortium focuses on three main objectives, i.e.: (1) improving young people's help-s...

journal_title：Trials

authors： Kaess M,Bauer S

更新日期：2019-01-22 00:00:00

abstract：BACKGROUND:Increasing numbers of patients are surviving critical illness, but survival may be associated with a constellation of physical and psychological sequelae that can cause ongoing disability and reduced health-related quality of life. Limited evidence currently exists to guide the optimum structure, timing, and...

journal_title：Trials

authors： Ramsay P,Salisbury LG,Merriweather JL,Huby G,Rattray JE,Hull AM,Brett SJ,Mackenzie SJ,Murray GD,Forbes JF,Walsh TS,RECOVER trial collaboration.

更新日期：2014-01-29 00:00:00

abstract：BACKGROUND:Diabetes mellitus is associated with risk of sudden sensorineural hearing loss (SSNHL). Systemic and intratympanic corticosteroids are the two primary treatments for SSNHL in patients with diabetes mellitus. The benefit of intratympanic compared to systemic treatment is the reduced systemic steroid exposure ...

journal_title：Trials

authors： Yang W,Li X,Zhong J,Mei X,Liu H,Yang L,Lu L,Hu H

更新日期：2020-02-03 00:00:00

abstract：BACKGROUND:As intensive care mortality is high, end of life is a subject of major concern for intensivists. In this context, relatives are particularly vulnerable and prone to post-ICU syndrome, in the form of high levels of anxiety, depression, post-traumatic stress, and complicated grief. Grieving families suffer fro...

journal_title：Trials

authors： Kentish-Barnes N,Chevret S,Azoulay E

更新日期：2016-02-20 00:00:00

abstract：BACKGROUND:Chronic obstructive pulmonary disease (COPD) is a common disease, associated with cardiovascular disease. Many patients use (long-acting) bronchodilators, whilst they continue smoking alongside. We hypothesised an interaction between bronchodilators and smoking that enhances smoke exposure, and hence cardiov...

journal_title：Trials

authors： van Dijk WD,Scheepers PT,Cremers R,Lenders JW,Klerx W,van Weel C,Schermer TR,Heijdra Y

更新日期：2011-02-10 00:00:00

abstract：BACKGROUND/AIMS:Prediabetes and diabetes disproportionately impact Latino youth, yet few diabetes prevention programs have prioritized inclusion of this underrepresented population. This report describes the recruitment process, yields, associated costs, and phenotypic characteristics of Latino youth with obesity and p...

journal_title：Trials

authors： Vander Wyst KB,Olson ML,Hooker E,Soltero EG,Konopken YP,Keller CS,Castro FG,Williams AN,Fernández ADR,Patrick DL,Ayers SL,Hu HH,Peña A,Pimentel J,Knowler WC,Shaibi GQ

更新日期：2020-08-14 00:00:00

abstract：BACKGROUND:Practicing activities improves recovery after stroke, but many people in hospital do little activity. Feedback on activity using an accelerometer is a potential method to increase activity in hospital inpatients. This study's goal is to investigate the effect of feedback, enabled by a Smart watch, on daily p...

journal_title：Trials

authors： Dong Y,Steins D,Sun S,Li F,Amor JD,James CJ,Xia Z,Dawes H,Izadi H,Cao Y,Wade DT,Smart watch activity feedback trial committee (SWAFT).

更新日期：2018-03-09 00:00:00

abstract：BACKGROUND:The ACTION study (Attention deficit hyperactivity disorder Controlled Trial Investigation Of a Non-stimulant) is a multi-center, double-blind, randomized cross-over trial of the non-stimulant medication, Atomoxetine, in children and adolescents with attention deficit hyperactivity disorder (ADHD). The primar...

journal_title：Trials

authors： Tsang TW,Kohn MR,Hermens DF,Clarke SD,Clark CR,Efron D,Cranswick N,Lamb C,Williams LM

更新日期：2011-03-13 00:00:00

abstract：BACKGROUND:In Germany, clinical trials and comparative effectiveness studies in primary care are still very rare, while their usefulness has been recognised in many other countries. A network of researchers from German academic general practice has explored the reasons for this discrepancy. METHODS:Based on a comprehe...

journal_title：Trials

authors： Hummers-Pradier E,Bleidorn J,Schmiemann G,Joos S,Becker A,Altiner A,Chenot JF,Scherer M,German ‘Clinical Trials in German General Practice Network’.

更新日期：2012-11-08 00:00:00

abstract：BACKGROUND:Cleft palate (CP) has an incidence of approximately 1 in 700. Children with CP are also susceptible to otitis media with effusion (OME), with approximately 90% experiencing nontrivial OME. There are several approaches to the management of OME in children with CP. The Management of Otitis Media with Effusion ...

journal_title：Trials

authors： Harman NL,Bruce IA,Callery P,Tierney S,Sharif MO,O'Brien K,Williamson PR

更新日期：2013-03-12 00:00:00

abstract：BACKGROUND:Failure to collect outcome data in randomised trials can result in bias and loss of statistical power. Further evaluations of strategies to increase retention are required. We assessed the effectiveness of two strategies for retention in a randomised prevention trial using a two-by-two factorial randomised s...

journal_title：Trials

authors： Bradshaw LE,Montgomery AA,Williams HC,Chalmers JR,Haines RH

更新日期：2020-06-08 00:00:00

abstract：BACKGROUND:The preliminary results of a randomised controlled trial are presented. The aim of the trial is to determine the efficacy, feasibility and acceptability of email-delivered psychological interventions with telephone support, for adults injured in a motor vehicle crash engaged in seeking compensation. The prim...

journal_title：Trials

authors： Guest R,Tran Y,Gopinath B,Cameron ID,Craig A

更新日期：2018-06-27 00:00:00

abstract：BACKGROUND:Surgery induces insulin resistance that might be alleviated by a nutritional drink given preoperatively. The authors hypothesized that some of the beneficial effects of the drink could be attributed to the volume component (approximately 1 L) rather than to the nutrients. METHODS:Sixty patients scheduled fo...

journal_title：Trials

authors： Ljunggren S,Hahn RG

更新日期：2012-07-02 00:00:00

abstract：BACKGROUND:The Pneumatic CompREssion for Preventing VENous Thromboembolism (PREVENT) trial evaluates the effect of adjunctive intermittent pneumatic compression (IPC) with pharmacologic thromboprophylaxis compared to pharmacologic thromboprophylaxis alone on venous thromboembolism (VTE) in critically ill adults. METHO...

journal_title：Trials

authors： Arabi Y,Al-Hameed F,Burns KEA,Mehta S,Alsolamy S,Almaani M,Mandourah Y,Almekhlafi GA,Al Bshabshe A,Finfer S,Alshahrani M,Khalid I,Mehta Y,Gaur A,Hawa H,Buscher H,Arshad Z,Lababidi H,Al Aithan A,Jose J,Abdukahil SA

更新日期：2018-03-15 00:00:00

abstract：BACKGROUND:Physical exercise interventions have been extensively advocated for the treatment of obesity; however, clinical trials evaluating the effectiveness of exercise interventions on weight control show controversial results. Compensatory mechanisms through a decrease in energy expenditure and/or an increase in ca...

journal_title：Trials

authors： Paravidino VB,Mediano MFF,Silva ICM,Wendt A,Del Vecchio FB,Neves FA,Terra BS,Gomes EAC,Moura AS,Sichieri R

更新日期：2018-03-07 00:00:00

abstract：BACKGROUND:Lower urinary tract symptoms (LUTS) can relate to urinary storage or voiding. In men, the prevalence and severity of LUTS increases with age, with a significant impact on quality of life. The majority of men presenting with LUTS are managed by their general practitioner (GP) in the first instance, with conse...

journal_title：Trials

authors： Frost J,Lane JA,Cotterill N,Fader M,Hackshaw-McGeagh L,Hashim H,Macaulay M,MacNeill SJ,Noble S,Rees J,Ridd MJ,Robles L,Taylor G,Taylor J,Drake MJ,Worthington J

更新日期：2019-09-02 00:00:00

abstract：BACKGROUND:It was reported that prolonging the injection time or diluting administration can reduce the incidence of opioid-induced cough. However, the incidence of sufentanil-induced cough (SIC) via a standardized infusion rate is unclear. A mechanical dropper is an infusion filtering device commonly used for intraven...

journal_title：Trials

authors： Liu M,Li Z,Wang S,Liu Y,Zhong X,He R,Li F

更新日期：2019-03-15 00:00:00

abstract：BACKGROUND:Despite efforts to improve the accuracy and transparency of the design, conduct, and reporting of randomised controlled trials (RCTs), deficiencies remain. Such deficiencies contribute to significant, avoidable waste of health research investment and impede reproducibility. This study aimed to synthesise and...

journal_title：Trials

authors： Clyne B,Boland F,Murphy N,Murphy E,Moriarty F,Barry A,Wallace E,Devine T,Smith SM,Devane D,Murphy A,Fahey T

更新日期：2020-06-08 00:00:00

abstract：BACKGROUND:Heart valve diseases are common with an estimated prevalence of 2.5% in the Western world. The number is rising due to an ageing population. Once symptomatic, heart valve diseases are potentially lethal, and heavily influence daily living and quality of life. Surgical treatment, either valve replacement or r...

journal_title：Trials

authors： Sibilitz KL,Berg SK,Hansen TB,Risom SS,Rasmussen TB,Hassager C,Køber L,Steinbrüchel D,Gluud C,Winkel P,Thygesen LC,Hansen JL,Schmid JP,Conraads V,Brocki BC,Zwisler AD

更新日期：2013-04-22 00:00:00

abstract：BACKGROUND:Patients with type 2 diabetes (T2DM) are at increased risk for macrovascular events as well as for microvascular complications. There is evidence that in patients with coronary artery disease (CAD), about 35 % suffer from manifest T2DM. Early glucose-lowering intervention in subjects with T2DM has been demon...

journal_title：Trials

authors： Tripolt NJ,Aberer F,Riedl R,Hutz B,Url J,Dimsity G,Meinitzer A,Stojakovic T,Hödl R,Brodmann M,Hafner F,Sourij H

更新日期：2016-10-13 00:00:00

abstract：BACKGROUND:Approximately 40% of the newly diagnosed patients with advanced ovarian cancer are aged 70 years or older. Standard treatment for advanced disease consists of cytoreductive surgery and combination chemotherapy. In older patients, standard treatment is often withheld or prematurely stopped due to suspected fr...

journal_title：Trials

authors： van Soolingen NJ,Smorenburg CH,Hamaker ME,Groen WG,Retèl VP,Lok CAR,van de Poll-Franse LV,Trum JW

更新日期：2020-02-22 00:00:00

abstract：BACKGROUND:Cognitive behaviour therapy (CBT) is an effective treatment for depression. However, CBT is a complex therapy that requires highly trained and qualified practitioners, and its scalability is therefore limited by the costs of training and employing sufficient therapists to meet demand. Behavioural activation ...

journal_title：Trials

authors： Rhodes S,Richards DA,Ekers D,McMillan D,Byford S,Farrand PA,Gilbody S,Hollon SD,Kuyken W,Martell C,O'Mahen HA,O'Neill E,Reed N,Taylor RS,Watkins ER,Wright KA

更新日期：2014-01-21 00:00:00

abstract：BACKGROUND:Meta-analyses of randomized controlled trials (RCTs) have shown that exercise has beneficial effects on quality of life (QoL) in patients with breast cancer. However, these effects were often small. Blinding in an exercise trial is not possible, which has the possible disadvantage of difficult accrual, drop-...

journal_title：Trials

authors： Gal R,Monninkhof EM,Groenwold RHH,van Gils CH,van den Bongard DHJG,Peeters PHM,Verkooijen HM,May AM

更新日期：2017-10-27 00:00:00

abstract：BACKGROUND:The clinical benefits of bioimpedance spectroscopy (BIS)-guided fluid management in patients on hemodialysis have been widely demonstrated. However, no previous reports have evaluated the effect of regular and serial BIS-guided fluid management on the residual renal function (RRF) in patients on peritoneal d...

journal_title：Trials

authors： Baek SH,Oh KH,Kim S,Kim DK,Joo KW,Oh YK,Han BG,Chang JH,Chung W,Kim YS,Na KY

更新日期：2014-11-06 00:00:00

abstract：BACKGROUND:There is a large treatment gap with few community services for people with schizophrenia in low income countries largely due to the shortage of specialist mental healthcare human resources. Community based rehabilitation (CBR), involving lay health workers, has been shown to be feasible, acceptable and more ...

journal_title：Trials

authors： Chatterjee S,Leese M,Koschorke M,McCrone P,Naik S,John S,Dabholkar H,Goldsmith K,Balaji M,Varghese M,Thara R,Patel V,Thornicroft G,COmmunity care for People with Schizophrenia in India (COPSI) group.

更新日期：2011-01-13 00:00:00

abstract：BACKGROUND:The reported incidence of peripheral intravenous catheter (PIV) failure has been as high as 69%. This is in part due to inadequate stabilisation or securement to the skin, which allows micro-motion of the catheter within the vein. METHODS:A pilot open randomised controlled trial of 300 patients was conducte...

journal_title：Trials

authors： Marsh N,Larsen E,Genzel J,Mihala G,Ullman AJ,Kleidon T,Cadigan S,Rickard CM

更新日期：2018-10-30 00:00:00

abstract：BACKGROUND:It is widely agreed that triglyceride (TG)-lowering therapy is imperative in early hypertriglyceridemia-induced acute pancreatitis (HTG-AP). Intravenous insulin with or without heparin, and plasmapheresis are available regimens. However, there is no consensus on first-line therapy. METHODS/DESIGN:The Bi-TPA...

journal_title：Trials

authors： Song X,Shi D,Cui Q,Yu S,Yang J,Song P,Walline J,Xu J,Zhu H,Yu X

更新日期：2019-06-18 00:00:00