Editorial Promoting Help-seeking using E-Technology for ADolescents: The ProHEAD consortium.

abstract：BACKGROUND:Ascites is one of the most common complications of cirrhosis. Umbilical therapy with traditional Chinese medicines has been increasingly prescribed to treat cirrhotic ascites. However, high-quality evidence from clinical trials supporting such application of traditional Chinese medicines remains limited. The...

journal_title：Trials

authors： Yang X,Ru S,Luo L,Lv X,Bai W,Zhang F,Jiang F

更新日期：2019-02-13 00:00:00

abstract：BACKGROUND:Whiplash-associated disorders (WAD) are an enormous and costly burden to Australian society. Up to 50% of people who experience a whiplash injury will never fully recover. Whiplash is resistant to treatment and no early management approach has yet been shown to prevent chronic pain. The early presence of cen...

journal_title：Trials

authors： Nikles J,Keijzers G,Mitchell G,Schug S,Ware R,McLean SA,Connelly L,Gibson S,Farrell SF,Sterling M

更新日期：2018-01-17 00:00:00

abstract：BACKGROUND:Suicide risk among individuals with schizophrenia (SZ) is intractably high, with over 40% of individuals attempting to take their own lives during their lifetime and an estimated 5-10% completing suicide. At present, available pharmacological and psychotherapeutic treatments offer limited risk reduction bene...

journal_title：Trials

authors： Beck-Felts K,Goodman M,Ospina LH,Wall M,McEvoy J,Jarskog LF,Ballon JS,Bartels MN,Buchsbaum R,Sloan RP,Stroup TS,Kimhy D

更新日期：2020-10-21 00:00:00

abstract：BACKGROUND:Staphylococcus aureus bacteremia (SAB) is frequently encountered in the hospital setting, and current guidelines recommend at least 14 days of antibiotic treatment for SAB in order to minimize risks of secondary deep infections and relapse. However, evidence to support these treatment recommendations remains...

journal_title：Trials

authors： Thorlacius-Ussing L,Andersen CØ,Frimodt-Møller N,Knudsen IJD,Lundgren J,Benfield TL

更新日期：2019-05-02 00:00:00

abstract：BACKGROUND:Endoscopic ultrasonography (EUS)-guided drainage has become the first-line therapy for late peri-pancreatic fluid collection (PFC). Double pigtail plastic stents (DPPS) and lumen-apposing metal stents (LAMS) are commonly used for PFC drainage. Recently, a multi-institutional consensus on PFC drainage has rec...

journal_title：Trials

authors： Zhu HY,Xie P,Song YX,Li ZS,Jin ZD,Du YQ

更新日期：2018-10-11 00:00:00

abstract：:AbstractFollowing publication of the original article [1], the authors notified us of a typing error in spelling Dr. Asario's name. The original publication has been corrected. ...

journal_title：Trials

authors： Curley MAQ,Gedeit RG,Dodson BL,Amling JK,Soetenga DJ,Corriveau CO,Asaro LA,Wypij D,RESTORE Investigative Team.

更新日期：2019-01-07 00:00:00

abstract：BACKGROUND:Radiation therapy (RT) of bone metastases provides an important treatment approach in palliative care treatment concepts. As a consequence of treatment, the extent of radiation-induced toxicity is a crucial feature with consequences to a patient's quality of life. In this context this study aims at reducing ...

journal_title：Trials

authors： Meyerhof E,Sprave T,Welte SE,Nicolay NH,Förster R,Bostel T,Bruckner T,Schlampp I,Debus J,Rief H

更新日期：2017-03-03 00:00:00

abstract：RATIONALE:Aspiration, infections, and fever are common in the first days after stroke, especially in older patients. The occurrence of these complications has been associated with an increased risk of death or dependency. AIMS AND DESIGN:PREvention of Complications to Improve OUtcome in elderly patients with acute Str...

journal_title：Trials

authors： de Jonge JC,Woodhouse LJ,Reinink H,van der Worp HB,Bath PM,PRECIOUS investigators.

更新日期：2020-10-26 00:00:00

abstract：BACKGROUND:The construction of a colostomy is a common procedure, but the evidence for the different parts of the construction of the colostomy is lacking. Parastomal hernia is a common complication of colostomy formation. The aim of this study is to standardise the colostomy formation and to compare three types of col...

journal_title：Trials

authors： Correa Marinez A,Erestam S,Haglind E,Ekelund J,Angerås U,Rosenberg J,Helgstrand F,Angenete E

更新日期：2014-06-27 00:00:00

abstract：BACKGROUND:Emergency department attendances with chest pain requiring assessment for acute coronary syndrome (ACS) are a major global health issue. Standard assessment includes history, examination, electrocardiogram (ECG) and serial troponin testing. Computerised tomography coronary angiography (CTCA) enables addition...

journal_title：Trials

authors： Gray AJ,Roobottom C,Smith JE,Goodacre S,Oatey K,O'Brien R,Storey RF,Na L,Lewis SC,Thokala P,Newby DE

更新日期：2016-12-07 00:00:00

abstract：BACKGROUND:The success of a clinical trial is often dependant on whether recruitment targets can be met in the required time frame. Despite an increase in research into the benefits of exercise in people with multiple sclerosis (PwMS), no trial has reported detailed data on effective recruitment strategies for large-sc...

journal_title：Trials

authors： Carter A,Humphreys L,Snowdon N,Sharrack B,Daley A,Petty J,Woodroofe N,Saxton J

更新日期：2015-10-15 00:00:00

abstract：BACKGROUND:Youth depression is highly prevalent and is related to impairments in academic, social and behavioural functioning. Evidence-based treatments are available, but many young people do not respond or sufficiently recover with first-line options, and a significant proportion experience relapse. Consequently, the...

journal_title：Trials

authors： Hallford DJ,Carmichael AM,Austin DW,Takano K,Raes F,Fuller-Tyszkiewicz M

更新日期：2020-01-14 00:00:00

abstract：BACKGROUND:Disinvestment from inefficient or ineffective health services is a growing priority for health care systems. Provision of allied health services over the weekend is now commonplace despite a relative paucity of evidence supporting their provision. The relatively high cost of providing this service combined w...

journal_title：Trials

authors： Haines TP,O'Brien L,Mitchell D,Bowles KA,Haas R,Markham D,Plumb S,Chiu T,May K,Philip K,Lescai D,McDermott F,Sarkies M,Ghaly M,Shaw L,Juj G,Skinner EH

更新日期：2015-04-02 00:00:00

abstract：BACKGROUND:Patients with testicular germ cell cancer (GCC) have a high cure rate; however, cancer-related fatigue is the most common complication among patients with GCC undergoing treatment with chemotherapy. Although exercise is widely recommended, information about the physio-pathological effects of cancer therapy o...

journal_title：Trials

authors： Cuesta-Vargas AI,Carabantes F,Caracuel Z,Conejo I,Alba E

更新日期：2016-01-05 00:00:00

abstract：BACKGROUND:Individual patient data (IPD) meta-analysis is considered the "gold standard" for exploring the effectiveness of interventions in different subgroups of patients. However, obtaining IPD is time-consuming and contact with the researchers responsible for the original trials is usually required. To date, there ...

journal_title：Trials

authors： Veroniki AA,Straus SE,Ashoor H,Stewart LA,Clarke M,Tricco AC

更新日期：2016-03-15 00:00:00

abstract：BACKGROUND:Surgical site infections (SSI) remain one of the most common complications in conventional abdominal surgery with an incidence between 4% and 19% (Sandini et al., Medicine (Baltimore) 95:e4057, 2016) in the literature. It is unclear whether the use of coated suture material for skin closure reduces the risk ...

journal_title：Trials

authors： Matz D,Teuteberg S,Wiencierz A,Soysal SD,Heizmann O

更新日期：2019-07-02 00:00:00

abstract：BACKGROUND:Atopic dermatitis (AD) is associated with reduced skin microbial diversity and overgrowth of Staphylococcus (S.) aureus. However, the importance of S. aureus colonisation in the complex pathogenesis remains unclear and studies on the effect of anti-staphylococcal therapy in non-infected AD show contradictory...

journal_title：Trials

authors： Totté J,de Wit J,Pardo L,Schuren F,van Doorn M,Pasmans S

更新日期：2017-08-31 00:00:00

abstract：BACKGROUND:Currently, there still is no treatment that eliminates tinnitus in all patients. Recent studies have shown that Tinnitus Retraining Therapy (TRT) significantly improves quality of life for tinnitus patients. Also, several studies have reported that transcranial Direct Current Stimulation (tDCS) has a positiv...

journal_title：Trials

authors： Rabau S,Van Rompaey V,Van de Heyning P

更新日期：2015-11-10 00:00:00

abstract：BACKGROUND:Heart valve diseases are common with an estimated prevalence of 2.5% in the Western world. The number is rising due to an ageing population. Once symptomatic, heart valve diseases are potentially lethal, and heavily influence daily living and quality of life. Surgical treatment, either valve replacement or r...

journal_title：Trials

authors： Sibilitz KL,Berg SK,Hansen TB,Risom SS,Rasmussen TB,Hassager C,Køber L,Steinbrüchel D,Gluud C,Winkel P,Thygesen LC,Hansen JL,Schmid JP,Conraads V,Brocki BC,Zwisler AD

更新日期：2013-04-22 00:00:00

abstract：BACKGROUND:Bipolar disorder (BD) is commonly associated with cognitive and functional impairments even during remission periods, and although a growing number of studies have demonstrated the benefits of psychotherapy as an add-on to pharmacological treatment, its effectiveness appears to be less compelling in severe p...

journal_title：Trials

authors： Gomes BC,Rocca CC,Belizario GO,Lafer B

更新日期：2017-03-28 00:00:00

abstract：BACKGROUND:This descriptive study aimed to investigate adolescents' motivations for participating in a randomised controlled trial (RCT), to explore the understanding that the young people had regarding a number of aspects of the trial design, to examine whether or not they found participation in the trial to be accept...

journal_title：Trials

authors： Midgley N,Isaacs D,Weitkamp K,Target M

更新日期：2016-07-28 00:00:00

abstract：BACKGROUND:Low back pain is highly prevalent and a major source of disability worldwide. Spa therapy is frequently used to treat low back pain, but the associated level of evidence for efficacy is insufficient. To fill this knowledge gap, this protocol proposes an appropriately powered, prospective, evaluator-blinded, ...

journal_title：Trials

authors： Forestier R,Suehs C,Françon A,Marty M,Genevay S,Sellam J,Chauveton C,Erol Forestier FB,Molinari N

更新日期：2020-05-11 00:00:00

abstract：BACKGROUND:The gap between the level of care recommended by evidence-based clinical practice guidelines and the actual care delivered to patients in practice has been well established. The Canadian Diabetes Association (CDA) created an implementation strategy to improve the implementation of its 2008 guidelines. This s...

journal_title：Trials

authors： Shah BR,Bhattacharyya O,Yu C,Mamdani M,Parsons JA,Straus SE,Zwarenstein M

更新日期：2010-04-23 00:00:00

abstract：BACKGROUND:Low back pain (LBP) is a common cause of disability among U.S. military personnel. Approximately 20% of all diagnoses resulting in disability discharges are linked to back-related conditions. Because LBP can negatively influence trunk muscle strength, balance, and endurance, the military readiness of active-...

journal_title：Trials

authors： Vining R,Minkalis A,Long CR,Corber L,Franklin C,Gudavalli MR,Xia T,Goertz CM

更新日期：2018-12-05 00:00:00

abstract：BACKGROUND:In studies comparing different prosthetic treatment concepts the repeated loss of teeth was chosen as the primary outcome. The resulting data appear to represent a data structure of recurrent events. However, the application of an existing method for recurrent events is far from straightforward. Often only t...

journal_title：Trials

authors： Diebner HH,Marré B,Roeder I,Walter MH

更新日期：2016-05-17 00:00:00

abstract：BACKGROUND:Endovascular iliac artery interventions rely on the use of two-dimensional digital subtraction angiographies with an iodinated contrast agent and ionizing radiation. The amount of iodinated contrast agent should be limited because of its potentially nephrotoxic effects. Three-dimensional (3D) image fusion re...

journal_title：Trials

authors： Goudeketting SR,Heinen SGH,de Haan MW,Sailer AM,van den Heuvel DAF,van Strijen MJ,de Vries JPM

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Spleen qi deficiency (SQD), a syndrome based on traditional Chinese medicine (TCM) theory, is common in patients after radical gastrectomy. SQD manifests with chronic gastrointestinal disorders and systemic symptoms and is challenging to manage. Hou Gu Mi Xi (HGMX) is a dietary TCM formula for SQD. This stud...

journal_title：Trials

authors： Zhou X,Yan DM,Zhu WF,Liu WJ,Nie HY,Xu S,Jiang YP,Zhang KH,Fu Y,Wan YY,Yu XY,Li H,Sun X,Chen XF

更新日期：2019-06-10 00:00:00

abstract：BACKGROUND:To prevent clinical relapse in teenagers with inflammatory bowel disease (IBD) there is a need to monitor disease activity continuously. Timely optimisation of medical treatment may nip a preclinical relapse in the bud and change the natural course of IBD. Traditionally, disease monitoring is done during sch...

journal_title：Trials

authors： Heida A,Dijkstra A,Groen H,Muller Kobold A,Verkade H,van Rheenen P

更新日期：2015-06-16 00:00:00

abstract：BACKGROUND:Intellectual disability (ID) is characterized by limitations in intellectual functioning and adaptive behavior. Adults with ID exhibit higher rates of obesity and poorer health status compared to the general population. Continuity of care and barriers to health-related activities may contribute to the poorer...

journal_title：Trials

authors： Neumeier WH,Guerra N,Thirumalai M,Geer B,Ervin D,Rimmer JH

更新日期：2017-10-23 00:00:00

abstract：BACKGROUND:Impulsivity and compulsivity are related to emotional and social maladjustment and often underlie psychiatric disorders. Recently, alterations in microbiota composition have been shown to have implications for brain development and social behavior via the microbiota-gut-brain axis. However, the exact mechani...

journal_title：Trials

authors： Arteaga-Henríquez G,Rosales-Ortiz SK,Arias-Vásquez A,Bitter I,Ginsberg Y,Ibañez-Jimenez P,Kilencz T,Lavebratt C,Matura S,Reif A,Rethelyi J,Richarte V,Rommelse N,Siegl A,Ramos-Quiroga JA

更新日期：2020-02-11 00:00:00