The effect of Transcranial Direct Current Stimulation in addition to Tinnitus Retraining Therapy for treatment of chronic tinnitus patients: a study protocol for a double-blind controlled randomised trial.

abstract：BACKGROUND:Although conventional laparoscopic and hand-assisted laparoscopic surgery for colorectal cancer is widely used today, there remain many technical challenges especially for right colon cancer in obese patients. Herein, we develop a novel hand-assisted laparoscopic surgery (HALS) with complete mesocolic excisi...

journal_title：Trials

authors： Yang X,Wu Q,Jin C,He W,Wang M,Yang T,Wei M,Deng X,Meng W,Wang Z

更新日期：2017-07-26 00:00:00

abstract：BACKGROUND:Research shows that more than half of the people taking medication for a chronic condition are non-adherent. Nonadherence hinders disease control with a burden on patient quality of life and healthcare systems. We developed a tool that provides insight into nonadherence risks and barriers for medication-adhe...

journal_title：Trials

authors： Hilbink M,Lacroix J,Bremer-van der Heiden L,van Halteren A,Teichert M,van Lieshout J

更新日期：2016-06-03 00:00:00

abstract：BACKGROUND:Automatic tendencies to approach drug-related cues have been linked to the development and maintainance of harmful drug-taking behavior. Recent studies have demonstrated that these automatic approach tendencies can be targeted directly by means of cognitive bias modification (CBM). Moreover, changing those a...

journal_title：Trials

authors： Machulska A,Kleinke K,Eiler TJ,Grünewald A,Brück R,Jahn K,Niehaves B,Gethmann CF,Klucken T

更新日期：2019-12-12 00:00:00

abstract：BACKGROUND:Pancreatic ductal adenocarcinoma (PDA) is one of the most aggressive malignancies with marked resistance to chemo- and radiotherapy. PDA-cancer stem cells (CSCs) are not targeted by current therapies and may be a reason for poor prognosis. Studies indicate that diets rich in cabbage, broccoli, and cauliflowe...

journal_title：Trials

authors： Lozanovski VJ,Houben P,Hinz U,Hackert T,Herr I,Schemmer P

更新日期：2014-06-03 00:00:00

abstract：:After publication of our article [1] we became aware that several sections of text in our Methods section were copied from a previously published article [2]. We would like to formally apologize and give credit to the authors of that article [2]: Chris Smith, Uk Vannak, Ly Sokhey, Thoai D Ngo, Judy Gold, Khemrin Khut,...

journal_title：Trials

authors： Brody C,Tuot S,Chhoun P,Swendeman D,Kaplan KC,Yi S

更新日期：2019-12-09 00:00:00

abstract：BACKGROUND:Venous thromboembolism (VTE) remains a common problem in critically ill patients. Pharmacologic prophylaxis is currently the standard of care based on high-level evidence from randomized controlled trials. However, limited evidence exists regarding the effectiveness of intermittent pneumatic compression (IPC...

journal_title：Trials

authors： Arabi YM,Alsolamy S,Al-Dawood A,Al-Omari A,Al-Hameed F,Burns KE,Almaani M,Lababidi H,Al Bshabshe A,Mehta S,Al-Aithan AM,Mandourah Y,Almekhlafi G,Finfer S,Abdukahil SA,Afesh LY,Dbsawy M,Sadat M

更新日期：2016-08-03 00:00:00

abstract：BACKGROUND:Idiopathic sudden sensorineural hearing loss (ISSNHL) is a major cause of deafness. Despite the advances in systemic therapy, some cases of ISSNHL are untreated, because the exact ISSNHL aetiology is unclear. Traditional Chinese medicine (TCM) has been used to treat diseases for thousands of years and is pop...

journal_title：Trials

authors： Fei YP,Zheng Y,Lai D,Zhong P,Lu JZ,Li G,Liu P

更新日期：2019-12-02 00:00:00

abstract：BACKGROUND:Qualitative methods are increasingly used to study the process of clinical trials and patients understanding of the rationale for trials, randomisation and reasons for taking part or refusing. Patients' understandings are inevitably influenced by the recruiting clinician's understanding of the trial, yet rel...

journal_title：Trials

authors： Ziebland S,Featherstone K,Snowdon C,Barker K,Frost H,Fairbank J

更新日期：2007-01-27 00:00:00

abstract：BACKGROUND:Recent clinical observations have reported the potential benefit of vagus nerve stimulation (VNS) as an adjunctive therapy for pediatric epilepsy. Preliminary evidence suggests that VNS treatment is effective for seizure reduction and mental development in young participants between 3 and 6 years of age who ...

journal_title：Trials

authors： Ji T,Yang Z,Liu Q,Liao J,Yin F,Chen Y,Zou L,Li B,Gao Y,Shu X,Huang S,Gao F,Liang J,Lin SF,Peng J,Song S,Wang J,Che C,Sun W,Tian M,Yang L,Hua Y,Hao Y,Cai L,Li L,Jiang Y

更新日期：2019-01-14 00:00:00

abstract：BACKGROUND:Intensive rehabilitation of patients with severe traumatic brain injury is generally applied in the subacute stages of the hospital stay. Few studies have assessed the association between early and intensive physical rehabilitation and functional outcomes. The aim of this trial is to assess the feasibility o...

journal_title：Trials

authors： Riberholt CG,Lindschou J,Gluud C,Mehlsen J,Møller K

更新日期：2018-11-08 00:00:00

abstract：BACKGROUND:In Germany, clinical trials and comparative effectiveness studies in primary care are still very rare, while their usefulness has been recognised in many other countries. A network of researchers from German academic general practice has explored the reasons for this discrepancy. METHODS:Based on a comprehe...

journal_title：Trials

authors： Hummers-Pradier E,Bleidorn J,Schmiemann G,Joos S,Becker A,Altiner A,Chenot JF,Scherer M,German ‘Clinical Trials in German General Practice Network’.

更新日期：2012-11-08 00:00:00

abstract：BACKGROUND:This study was carried out as a prospective clinical field study with the aim of evaluating the clinical performance of Equia Fil® with a nanofilled resin coating and the conventional Fuji IX GP® fast with an LC coating according to the World Dental Federation (FDI) restoration material evaluation criteria. ...

journal_title：Trials

authors： Klinke T,Daboul A,Turek A,Frankenberger R,Hickel R,Biffar R

更新日期：2016-05-08 00:00:00

abstract：OBJECTIVES:To investigate the potential efficacy of Acacia Senegal extract Gum Arabic (GA) supplementation as immunomodulatory and anti-inflammatory dietary intervention among newly diagnosed COVID 19 Sudanese patients. To study the effect of GA on the level of cytokines, TNFα, IL8, IL6 IL10, CRP and the viral load. Se...

journal_title：Trials

authors： Kaddam L,Babiker R,Ali S,Satti S,Ali N,Elamin M,Mukhtar M,Elnimeiri M,Saeed A

更新日期：2020-09-05 00:00:00

abstract：BACKGROUND:The preliminary results of a randomised controlled trial are presented. The aim of the trial is to determine the efficacy, feasibility and acceptability of email-delivered psychological interventions with telephone support, for adults injured in a motor vehicle crash engaged in seeking compensation. The prim...

journal_title：Trials

authors： Guest R,Tran Y,Gopinath B,Cameron ID,Craig A

更新日期：2018-06-27 00:00:00

abstract：BACKGROUND:Cardiac surgery has been shown to result in a significant decrease of the antioxidant selenium, which is associated with the development of multiorgan dysfunction and increased mortality. Thus, a large-scale study is needed to investigate the effect of perioperative selenium supplementation on the occurrence...

journal_title：Trials

authors： Stoppe C,McDonald B,Rex S,Manzanares W,Whitlock R,Fremes S,Fowler R,Lamarche Y,Meybohm P,Haberthür C,Rossaint R,Goetzenich A,Elke G,Day A,Heyland DK

更新日期：2014-08-28 00:00:00

abstract：BACKGROUND:Allergic rhinitis is one of the most common health complaints worldwide. Complementary and alternative medical approaches have been employed to relieve allergic rhinitis symptoms and to avoid the side effects of conventional medication. Acupuncture has been widely used to treat patients with allergic rhiniti...

journal_title：Trials

authors： Kim JI,Lee MS,Jung SY,Choi JY,Lee S,Ko JM,Zhao H,Zhao J,Kim AR,Shin MS,Kang KW,Jung HJ,Kim TH,Liu B,Choi SM

更新日期：2009-07-14 00:00:00

abstract：BACKGROUND:The practice of traditional Chinese medicine (TCM) has a profound history in many Asian countries. TCM syndrome is a set of characteristic physical signs and symptoms shared by a group of patients. Syndrome diagnosis and treatment assignment according to the identified TCM syndrome is a long-held practice of...

journal_title：Trials

authors： Cao H,Zhai J,Mu W,Lei X,Cao H,Liu C,Shang H

更新日期：2014-03-19 00:00:00

abstract：BACKGROUND:Despite efforts to improve the accuracy and transparency of the design, conduct, and reporting of randomised controlled trials (RCTs), deficiencies remain. Such deficiencies contribute to significant, avoidable waste of health research investment and impede reproducibility. This study aimed to synthesise and...

journal_title：Trials

authors： Clyne B,Boland F,Murphy N,Murphy E,Moriarty F,Barry A,Wallace E,Devine T,Smith SM,Devane D,Murphy A,Fahey T

更新日期：2020-06-08 00:00:00

abstract：BACKGROUND:Verrucae are a common, infectious and sometimes painful problem. The optimal treatment for verrucae is unclear due to a lack of high quality randomised controlled trials. The primary objective of this study is to compare the clinical effectiveness of two common treatments for verrucae: cryotherapy using liqu...

journal_title：Trials

authors： Cockayne ES,EVERT Trial Team.

更新日期：2010-02-08 00:00:00

abstract：BACKGROUND:Depression and bipolar disorder are associated with reduced neural plasticity and deficits in memory, attention and executive function. Drug treatments for these affective disorders have insufficient clinical effects in a large group and fail to reverse cognitive deficits. There is thus a need for more effec...

journal_title：Trials

authors： Miskowiak KW,Vinberg M,Harmer CJ,Ehrenreich H,Knudsen GM,Macoveanu J,Hansen AR,Paulson OB,Siebner HR,Kessing LV

更新日期：2010-10-13 00:00:00

abstract：BACKGROUND:Endovascular iliac artery interventions rely on the use of two-dimensional digital subtraction angiographies with an iodinated contrast agent and ionizing radiation. The amount of iodinated contrast agent should be limited because of its potentially nephrotoxic effects. Three-dimensional (3D) image fusion re...

journal_title：Trials

authors： Goudeketting SR,Heinen SGH,de Haan MW,Sailer AM,van den Heuvel DAF,van Strijen MJ,de Vries JPM

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Youth depression is highly prevalent and is related to impairments in academic, social and behavioural functioning. Evidence-based treatments are available, but many young people do not respond or sufficiently recover with first-line options, and a significant proportion experience relapse. Consequently, the...

journal_title：Trials

authors： Hallford DJ,Carmichael AM,Austin DW,Takano K,Raes F,Fuller-Tyszkiewicz M

更新日期：2020-01-14 00:00:00

abstract：BACKGROUND:Previous interventions to increase physical activity and reduce cardiovascular risk factors have been targeted at individuals with established disease; less attention has been given to intervention among individuals with high risk for disease nor has there been determination of the influence of setting in wh...

journal_title：Trials

authors： Petrella RJ,Aizawa K,Shoemaker K,Overend T,Piche L,Marin M,Shapiro S,Atkin S

更新日期：2011-02-16 00:00:00

abstract：BACKGROUND:Patients with testicular germ cell cancer (GCC) have a high cure rate; however, cancer-related fatigue is the most common complication among patients with GCC undergoing treatment with chemotherapy. Although exercise is widely recommended, information about the physio-pathological effects of cancer therapy o...

journal_title：Trials

authors： Cuesta-Vargas AI,Carabantes F,Caracuel Z,Conejo I,Alba E

更新日期：2016-01-05 00:00:00

abstract：BACKGROUND:Around 35-45 % of people in contact with services for a first episode of psychosis are using cannabis. Cannabis use is associated with delays in remission, poorer clinical outcomes, significant increases in the risk of relapse, and lower engagement in work or education. While there is a clear need for effect...

journal_title：Trials

authors： Johnson S,Sheridan Rains L,Marwaha S,Strang J,Craig T,Weaver T,McCrone P,King M,Fowler D,Pilling S,Marston L,Omar RZ,Craig M,Hinton M

更新日期：2016-10-22 00:00:00

abstract：BACKGROUND:Intellectual disability (ID) is characterized by limitations in intellectual functioning and adaptive behavior. Adults with ID exhibit higher rates of obesity and poorer health status compared to the general population. Continuity of care and barriers to health-related activities may contribute to the poorer...

journal_title：Trials

authors： Neumeier WH,Guerra N,Thirumalai M,Geer B,Ervin D,Rimmer JH

更新日期：2017-10-23 00:00:00

abstract：BACKGROUND:Fibroblast growth factor 23 (FGF23) is associated with left ventricular hypertrophy (LVH) in patients with chronic kidney disease, and calcimimetic therapy reduces plasma concentrations of FGF23. It remains unknown whether treatment with the calcimimetic etelcalcetide (ETL) reduces LVH in patients on hemodia...

journal_title：Trials

authors： Dörr K,Kammer M,Reindl-Schwaighofer R,Lorenz M,Loewe C,Marculescu R,Erben R,Oberbauer R

更新日期：2019-10-24 00:00:00

abstract：BACKGROUND:We aimed to test whether a common set of key data items reported across high-impact neonatal clinical trials could be identified, and to quantify their completeness in routinely recorded United Kingdom neonatal data held in the National Neonatal Research Database (NNRD). METHODS:We systematically reviewed n...

journal_title：Trials

authors： Jawad S,Modi N,Prevost AT,Gale C

更新日期：2019-12-16 00:00:00

abstract：BACKGROUND:Evidence for benefit of high positive end-expiratory pressure (PEEP) is largely lacking for invasively ventilated, critically ill patients with uninjured lungs. We hypothesize that ventilation with low PEEP is noninferior to ventilation with high PEEP with regard to the number of ventilator-free days and bei...

journal_title：Trials

authors： Algera AG,Pisani L,Bergmans DCJ,den Boer S,de Borgie CAJ,Bosch FH,Bruin K,Cherpanath TG,Determann RM,Dondorp AM,Dongelmans DA,Endeman H,Haringman JJ,Horn J,Juffermans NP,van Meenen DM,van der Meer NJ,Merkus MP,Moenira

更新日期：2018-05-09 00:00:00

abstract：BACKGROUND:Distal pancreatectomy for benign and malignant tumours is the second most common surgical procedure on the pancreas. Postoperative pancreatic fistulas (POPF) represent the most significant clinical complication, causing prolongation of hospital stay and the need for additional diagnostic and therapeutic proc...

journal_title：Trials

authors： Hassenpflug M,Bruckner T,Knebel P,Diener MK,Büchler MW,Werner J

更新日期：2013-12-14 00:00:00