Effectiveness of an individualized program of muscular strength and endurance with aerobic training for improving germ cell cancer-related fatigue in men undergoing chemotherapy: EFICATEST study protocol for a randomized controlled trial.

abstract：BACKGROUND:Evidence for benefit of high positive end-expiratory pressure (PEEP) is largely lacking for invasively ventilated, critically ill patients with uninjured lungs. We hypothesize that ventilation with low PEEP is noninferior to ventilation with high PEEP with regard to the number of ventilator-free days and bei...

journal_title：Trials

authors： Algera AG,Pisani L,Bergmans DCJ,den Boer S,de Borgie CAJ,Bosch FH,Bruin K,Cherpanath TG,Determann RM,Dondorp AM,Dongelmans DA,Endeman H,Haringman JJ,Horn J,Juffermans NP,van Meenen DM,van der Meer NJ,Merkus MP,Moenira

更新日期：2018-05-09 00:00:00

abstract：BACKGROUND:Spontaneous recovery from articular cartilage injury is difficult, and the ongoing progression of disease can eventually lead to osteoarthritis. Currently, there is no effective non-surgical treatment for articular cartilage injury. Arthroscopic debridement and microfracture surgery are performed for fibroca...

journal_title：Trials

authors： Ma N,Wang H,Xu X,Wan Y,Liu Y,Wang M,Yu W,Dai Y,Peng J,Guo Q,Yu C,Lu S

更新日期：2017-11-06 00:00:00

abstract：BACKGROUND:Anxiety and affective disorders can be disabling and have a major impact on the ability to work. In Denmark, people with a mental disorder, and mainly non-psychotic disorders, represent a substantial and increasing part of those receiving disability pensions. Previous studies have indicated that Individual P...

journal_title：Trials

authors： Hellström L,Bech P,Nordentoft M,Lindschou J,Eplov LF

更新日期：2013-12-24 00:00:00

abstract：BACKGROUND:The prevalence of central obesity is constantly increasing, and visceral fat is associated with increased production of inflammatory factors and metabolic risk factors. Lutein might retard the development of metabolic disease through its antioxidant and anti-inflammatory properties. Furthermore, epidemiologi...

journal_title：Trials

authors： Zhou J,Zhao D,Wang N,Zeng Z,Wang C,Hao L,Peng X

更新日期：2020-01-06 00:00:00

abstract：:Data sharing from clinical trials is one way of promoting fair and transparent conduct of clinical trials. It would maximise the use of data and permit the exploration of additional hypotheses. On the other hand, the quality of secondary analyses cannot always be ascertained, and it may be unfair to investigators who ...

journal_title：Trials

authors： Mbuagbaw L,Foster G,Cheng J,Thabane L

更新日期：2017-02-14 00:00:00

abstract：BACKGROUND:Youth depression is highly prevalent and is related to impairments in academic, social and behavioural functioning. Evidence-based treatments are available, but many young people do not respond or sufficiently recover with first-line options, and a significant proportion experience relapse. Consequently, the...

journal_title：Trials

authors： Hallford DJ,Carmichael AM,Austin DW,Takano K,Raes F,Fuller-Tyszkiewicz M

更新日期：2020-01-14 00:00:00

abstract：BACKGROUND:There is a need for improvement of information provision and post-treatment care for cancer survivors. A Survivorship Care Plan (SCP) is recommended by the American Institute of Medicine and the Dutch Health Council, which is a summary of patients' course of treatment as a formal document, and includes recom...

journal_title：Trials

authors： van de Poll-Franse LV,Nicolaije KA,Vos MC,Pijnenborg JM,Boll D,Husson O,Ezendam NP,Boss EA,Hermans RH,Engelhart KC,Haartsen JE,Pijlman BM,Feijen HW,Mertens HJ,Nolting WE,van Beek JJ,Roukema JA,Kruitwagen RF

更新日期：2011-12-05 00:00:00

abstract：BACKGROUND:Spleen qi deficiency (SQD), a syndrome based on traditional Chinese medicine (TCM) theory, is common in patients after radical gastrectomy. SQD manifests with chronic gastrointestinal disorders and systemic symptoms and is challenging to manage. Hou Gu Mi Xi (HGMX) is a dietary TCM formula for SQD. This stud...

journal_title：Trials

authors： Zhou X,Yan DM,Zhu WF,Liu WJ,Nie HY,Xu S,Jiang YP,Zhang KH,Fu Y,Wan YY,Yu XY,Li H,Sun X,Chen XF

更新日期：2019-06-10 00:00:00

abstract：BACKGROUND:Lack of trust in parental support is a transdiagnostic risk factor for the development of psychological problems throughout the lifespan. Research suggests that children's cognitive attachment representations and related information processing biases could be an important target for interventions aiming to b...

journal_title：Trials

authors： Verhees MWFT,Ceulemans E,Bakermans-Kranenburg MJ,van IJzendoorn MH,de Winter S,Bosmans G

更新日期：2017-07-14 00:00:00

abstract：BACKGROUND:Exercise-based cardiac rehabilitation is a beneficial therapy for patients with chronic heart failure. The delivery of exercise-based cardiac rehabilitation should adopt an evidence-based approach, as well as be culturally appropriate and sensitive to individual needs and preferences. The Baduanjin Eight-Sil...

journal_title：Trials

authors： Chen X,Jiang W,Lin X,Lundborg CS,Wen Z,Lu W,Marrone G

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Coronary heart disease (CHD) has become a common cardiovascular disease that seriously threatens the health of people. As reperfusion in the early phase and drug therapy, especially percutaneous coronary intervention (PCI), have become widely used in the clinic, the mortality of acute myocardial infarction i...

journal_title：Trials

authors： Wang Y,Wang X,Wang J,Li B,Yu R,Hu Y,Li X,Peng G,Zhang M,Zhu M

更新日期：2020-03-20 00:00:00

abstract：BACKGROUND:Periprosthetic joint infection (PJI) affects approximately 1% of patients following total hip replacement (THR) and often results in severe physical and emotional suffering. Current surgical treatment options are debridement, antibiotics and implant retention; revision THR; excision of the joint and amputati...

journal_title：Trials

authors： Strange S,Whitehouse MR,Beswick AD,Board T,Burston A,Burston B,Carroll FE,Dieppe P,Garfield K,Gooberman-Hill R,Jones S,Kunutsor S,Lane A,Lenguerrand E,MacGowan A,Moore A,Noble S,Simon J,Stockley I,Taylor AH,Toms A

更新日期：2016-02-17 00:00:00

abstract：BACKGROUND:Transurethral resection of the prostate (TURP) has been the standard operation for benign prostatic obstruction (BPO) for 40 years, with approximately 25,000 procedures performed annually, and has remained largely unchanged. It is generally a successful operation, but has well-documented risks for the patien...

journal_title：Trials

authors： Worthington J,Taylor H,Abrams P,Brookes ST,Cotterill N,Noble SM,Page T,Swami KS,Lane JA,Hashim H

更新日期：2017-04-17 00:00:00

abstract：BACKGROUND:Untreated advanced hepatocellular carcinoma (HCC) is linked to poor prognosis. While sorafenib is the current recommended treatment for advanced HCC, radioembolisation (RE; also called selective internal radiation therapy or SIRT) with yttrium-90 microspheres has shown efficacy in cohort studies. However, th...

journal_title：Trials

authors： Vilgrain V,Abdel-Rehim M,Sibert A,Ronot M,Lebtahi R,Castéra L,Chatellier G,SARAH Trial Group.

更新日期：2014-12-03 00:00:00

abstract：BACKGROUND:The incidence of cancer has been staying at a high level worldwide in recent years. With advances in cancer diagnosis and therapy strategy, the survival rate of patients with cancer has been increasing, but the side effects of these treatments, especially chemotherapy, are obvious even when the chemotherapy ...

journal_title：Trials

authors： You JS,Chen JP,Chan JS,Lee HF,Wong MK,Yeung WF,Lao LX

更新日期：2016-07-26 00:00:00

abstract：BACKGROUND:As intensive care mortality is high, end of life is a subject of major concern for intensivists. In this context, relatives are particularly vulnerable and prone to post-ICU syndrome, in the form of high levels of anxiety, depression, post-traumatic stress, and complicated grief. Grieving families suffer fro...

journal_title：Trials

authors： Kentish-Barnes N,Chevret S,Azoulay E

更新日期：2016-02-20 00:00:00

abstract：BACKGROUND:Findings suggest approximately one in six people with intellectual disability engage in 'challenging behaviours', which include aggression towards others/property and self-injurious actions. In residential settings, actions of staff members can make challenging behaviours more likely to occur, or make these ...

journal_title：Trials

authors： Randell E,Hastings RP,McNamara R,Knight R,Gillespie D,Taylor Z

更新日期：2017-10-05 00:00:00

abstract：BACKGROUND:Increasing numbers of patients are surviving critical illness, but survival may be associated with a constellation of physical and psychological sequelae that can cause ongoing disability and reduced health-related quality of life. Limited evidence currently exists to guide the optimum structure, timing, and...

journal_title：Trials

authors： Ramsay P,Salisbury LG,Merriweather JL,Huby G,Rattray JE,Hull AM,Brett SJ,Mackenzie SJ,Murray GD,Forbes JF,Walsh TS,RECOVER trial collaboration.

更新日期：2014-01-29 00:00:00

abstract：BACKGROUND:The burden of acute gastroenteritis on children and their families continues to be enormous. Probiotics, defined as viable microbial preparations that have a beneficial effect on the health of the host, represent a rapidly expanding field. Although clinical trials in children with gastroenteritis have been p...

journal_title：Trials

authors： Freedman SB,Williamson-Urquhart S,Schuh S,Sherman PM,Farion KJ,Gouin S,Willan AR,Goeree R,Johnson DW,Black K,Schnadower D,Gorelick MH,Pediatric Emergency Research Canada (PERC) Gastroenteritis Study Group.

更新日期：2014-05-14 00:00:00

abstract：BACKGROUND:In coronary artery bypass grafting surgery, arterial conduits are preferred because of more favourable long-term patency and outcome. Anyway the greater saphenous vein continues to be the most commonly used bypass conduit. Minimally invasive endoscopic saphenous vein harvesting is increasingly being investig...

journal_title：Trials

authors： Campanella A,Bergamasco L,Macri L,Asioli S,Devotini R,Scipioni S,Barbaro S,Rispoli P,Rinaldi M

更新日期：2011-11-18 00:00:00

abstract：BACKGROUND:This study was carried out as a prospective clinical field study with the aim of evaluating the clinical performance of Equia Fil® with a nanofilled resin coating and the conventional Fuji IX GP® fast with an LC coating according to the World Dental Federation (FDI) restoration material evaluation criteria. ...

journal_title：Trials

authors： Klinke T,Daboul A,Turek A,Frankenberger R,Hickel R,Biffar R

更新日期：2016-05-08 00:00:00

abstract：BACKGROUND:Compulsory submission of a checklist from the relevant reporting guideline is one of the most widespread journal requirements aiming to improve completeness of reporting. However, the current suboptimal levels of adherence to reporting guidelines observed in the literature may indicate that this journal poli...

journal_title：Trials

authors： Blanco D,Biggane AM,Cobo E,MiRoR network.

更新日期：2018-01-29 00:00:00

abstract：BACKGROUND:The FIRST-ABC trial comprises of two pragmatic, multicentre, parallel groups, non-inferiority randomised clinical trials designed to evaluate the clinical non-inferiority of first-line use of high flow nasal cannula (HFNC) to continuous positive airway pressure (CPAP) in critically ill children who require n...

journal_title：Trials

authors： Orzechowska I,Sadique MZ,Thomas K,Davis P,Morris KP,Mouncey PR,Peters MJ,Richards-Belle A,Tume LN,Ramnarayan P,Harrison DA

更新日期：2020-10-31 00:00:00

abstract：BACKGROUND:Current guidelines recommend treatment of significant coronary artery disease by concomitant coronary artery bypass grafting (CABG) in patients undergoing surgical aortic valve replacement. However there is no consensus as to how best to treat coronary disease in high-risk patients requiring transcatheter ao...

journal_title：Trials

authors： Khawaja MZ,Wang D,Pocock S,Redwood SR,Thomas MR

更新日期：2014-07-24 00:00:00

abstract：BACKGROUND:Burnout is an occupational syndrome that leads to mental health problems, job turnover, and patient safety events. Those caring for critically ill patients are especially susceptible due to high patient mortality, long hours, and regular encounters with trauma and ethical issues. Interventions to prevent bur...

journal_title：Trials

authors： Bateman ME,Hammer R,Byrne A,Ravindran N,Chiurco J,Lasky S,Denson R,Brown M,Myers L,Zu Y,Denson JL

更新日期：2020-12-11 00:00:00

abstract：BACKGROUND:Depression is one of the most common reasons for consulting in primary care. Acupuncture is a popular complementary therapy choice for depression but its evidence base is poor with more robust high quality trials being required. More than half of depressed patients experience painful symptoms, with severe pa...

journal_title：Trials

authors： Schroer S,Macpherson H

更新日期：2009-01-09 00:00:00

abstract：BACKGROUND:The traditional Chinese theory of acupuncture emphasizes that the intensity of acupuncture must reach a threshold to generate de qi (a specific and compound sensation during the acupuncture), which is necessary to achieve the best therapeutic effect. However, the notion that de qi must be achieved for maximu...

journal_title：Trials

authors： Chen Q,Zhang Q,Jiang L,Li X,Liu Y,Xie Y,Mu S,Liu Y,Wang X,Yu Y,Li M

更新日期：2014-07-24 00:00:00

abstract：BACKGROUND:Aneurysmal subarachnoid hemorrhage (aSAH) is a life-threatening condition that results from a ruptured cerebral vessel. Cerebral edema and vasospasm are common complications and frequently require treatment with hypertonic solutions, in particular hypertonic sodium chloride (NaCl). We have previously shown t...

journal_title：Trials

authors： Sadan O,Samuels O,Asbury WH,Hanfelt JJ,Singbartl K

更新日期：2018-11-14 00:00:00

abstract：BACKGROUND:There has been longstanding interesting in cognitive training for older adults with cognitive impairment. In this study, we will investigate the effects of working memory training, and explore augmentation strategies that could possibly consolidate the effects in older adults with mild neurocognitive disorde...

journal_title：Trials

authors： Cheng CP,Chan SS,Mak AD,Chan WC,Cheng ST,Shi L,Wang D,Lam LC

更新日期：2015-10-24 00:00:00

abstract：BACKGROUND:Tobacco smoking remains the leading preventable cause of death in the US. A hospital admission provides smokers with a unique opportunity to stop smoking because it requires temporary tobacco abstinence while illness may enhance motivation to quit. Hospital interventions must continue post-discharge to incre...

journal_title：Trials

authors： Rigotti NA,Schnitzer K,Davis EM,Regan S,Chang Y,Kelley JHK,Notier AE,Gilliam K,Douaihy A,Levy DE,Singer DE,Tindle HA

更新日期：2020-04-16 00:00:00