Prognostic significance of ALCAM (CD166/MEMD) expression in cutaneous melanoma patients.

abstract：:Primary involvement of skeletal muscle is a very rare event in ALK-1 positive anaplastic large cell lymphoma (ALCL). We describe a case of a 10-year old boy presenting with a three week history of pain and a palpable firm swelling at the dorsal aspect of the left thigh. Histological examination of the lesion revealed ...

journal_title：Diagnostic pathology

authors： Gaiser T,Geissinger E,Schattenberg T,Scharf HP,Dürken M,Dinter D,Rosenwald A,Marx A

更新日期：2012-04-12 00:00:00

abstract：UNLABELLED:Metastatic renal cell carcinoma in the gallbladder is extremely rare, with reported frequencies of less than 0.6% in large autopsy reviews. Only 40 cases were reported in the literature. We report a first case of gallbladder polypoid tumor revealing metastatic clear cell renal cell carcinoma, which demonstra...

journal_title：Diagnostic pathology

authors： Ghaouti M,Znati K,Jahid A,Zouaidia F,Bernoussi Z,El Fakir Y,Mahassini N

更新日期：2013-01-10 00:00:00

abstract：BACKGROUND:Primary non-Hodgkin lymphoma (NHL) of the breast represents 0.04-0.5% of malignant lesions of the breast and accounts for 1.7-2.2% of extra-nodal NHL. Most primary cases are of B-cell phenotype and only rare cases are of T-cell phenotype. Anaplastic large cell lymphoma (ALCL) is a rare T-cell lymphoma typica...

journal_title：Diagnostic pathology

authors： Bishara MR,Ross C,Sur M

更新日期：2009-04-02 00:00:00

abstract：UNLABELLED:We report a case of recurrent cutaneous necrotizing eosinophilic vasculitis (RCNEV) in a 57-year-old male. The patient presented with papules and pruritus of the lower limbs of more than 1 month duration, and with angioedema and intensively pruritic, necrotizing lesions of the bilateral anterior tibias and f...

journal_title：Diagnostic pathology

authors： Li W,Cao W,Song H,Ciu Y,Lu X,Zhang F

更新日期：2013-11-07 00:00:00

abstract：BACKGROUND:Osteosarcoma is the most common primary bone malignancy with high local aggressiveness and rapid metastasizing potential, resulting in poor survival. Increasing reports suggest that deregulated microRNAs (miRNAs) might provide novel therapeutic targets for cancers. However, the expression of miR-26a and miR-...

journal_title：Diagnostic pathology

authors： Taheriazam A,Bahador R,Karbasy SH,Jamshidi SM,Torkaman A,Yahaghi E,Shakeri M

更新日期：2015-09-17 00:00:00

abstract：BACKGROUND:Malignant gastrointestinal neuroectodermal tumor (GNET) is an extremely rare entity that was first described by Zambrano et al. in 2003 as "Clear cell sarcoma-like tumor of the gastrointestinal tract". It shares some of the histological features of clear cell sarcoma (CCS) but lacks the immunohistochemical r...

journal_title：Diagnostic pathology

authors： Alyousef MJ,Alratroot JA,ElSharkawy T,Shawarby MA,Al Hamad MA,Hashem TM,Alsayyah A

更新日期：2017-03-20 00:00:00

abstract：BACKGROUND:Primary diffuse large B cell lymphoma (DLBCL) of the uterus is rare, and primary DLBCL arising from a uterine leiomyoma (collision tumor) has not been reported in the literature. CASE PRESENTATION:We describe the clinical, histological, immunohistochemical, and molecular features of primary DLBCL arising fr...

journal_title：Diagnostic pathology

authors： Zhao L,Ma Q,Wang Q,Zeng Y,Luo Q,Xiao H

更新日期：2016-01-20 00:00:00

abstract：BACKGROUND:The tumor transformation mechanism of a plasmacytoid urothelial carcinoma remains unexplained. We describe the case of a plasmacytoid urothelial carcinoma of the renal pelvis in which the expression of zinc finger E-box-binding homeobox 1 (ZEB1), a key nuclear transcription factor in an epithelial-mesenchyma...

journal_title：Diagnostic pathology

authors： Takada-Owada A,Nozawa Y,Onozaki M,Noda S,Jamiyan T,Tokura Y,Nakazato Y,Kamai T,Ishida K

更新日期：2020-10-08 00:00:00

abstract：BACKGROUND:Tubular adenoma of the breast is a rare benign epithelial tumor and only a few literatures have been reported; so far, no cases of tubular adenoma occurred in the accessory breast have been reported in the English literature. Clinical presentation and management of our patient are discussed along with a revi...

journal_title：Diagnostic pathology

authors： Huang Y,Zhang H,Zhou Q,Ling L,Wang S

更新日期：2015-06-04 00:00:00

abstract：BACKGROUND:Epithelioid schwannoma as a rare variant poses a challenge to all pathologists, as this uncommon entity is extremely difficult to conclusively diagnose by morphological analyses on a resected sample alone owing to its unique histopathological features. However, few papers have described the detailed clinicop...

journal_title：Diagnostic pathology

authors： Yamada S,Kirishima M,Hiraki T,Higashi M,Hatanaka K,Tanimoto A

更新日期：2017-01-19 00:00:00

abstract：BACKGROUND:Pleomorphic xanthoastrocytoma is rare, accounting for <1 % of all central nervous system (CNS) neoplasms. Angiomatous pleomorphic xanthoastrocytoma is an extremely rare variant of pleomorphic xanthoastrocytoma, with only six cases reported thus far. CASE PRESENTATION:A 24-year-old Chinese female patient who...

journal_title：Diagnostic pathology

authors： Jiang YF,Liu Y,Wang YL,Cao HY,Wang L,Xu HT,Li QC,Qiu XS,Wang EH

更新日期：2016-08-09 00:00:00

abstract：UNLABELLED:Perivascular epithelioid cell tumors (PEComas) encompass a group of rare mesenchymal neoplasms, which typically have a perivascular location with dual melanocytic and muscular differentiation. They are found in a variety of localizations, though lesions in the liver are exceedingly rare. Because of their rar...

journal_title：Diagnostic pathology

authors： Ameurtesse H,Chbani L,Bennani A,Toughrai I,Beggui N,Kamaoui I,Elfatemi H,Harmouch T,Amarti A

更新日期：2014-07-17 00:00:00

abstract：:Concurrent hematologic malignancies are relatively rare. We encountered a case of concurrent acute myeloid leukemia (AML) and T lymphoblastic lymphoma. The bone marrow chromosome analysis showed the karyotype 46, XY, t(5;12)(q33;p13), which indicated presence of PDGFRB gene translocations. Therefore, this disease belo...

journal_title：Diagnostic pathology

authors： Chang H,Chuang WY,Sun CF,Barnard MR

更新日期：2012-02-22 00:00:00

abstract：:Primary liver tumors in children are rare with malignant hepatoblastoma being the most common neoplasm. In this report, we describe the diagnosis and clinical management of a large liver tumor in a 3-year-old child that displayed the features of both, conventional hepatoblastoma and malignant teratoma. Pathological as...

journal_title：Diagnostic pathology

authors： Moll A,Krenauer A,Bierbach U,Till H,Hirsch W,Leuschner I,Schmitz N,Wittekind C,Aigner T

更新日期：2009-11-12 00:00:00

abstract：BACKGROUND:The feasibility of evaluating an objective grading of cervical intraneoplasia lesions (CIN) is attempted using an automatic computerized system able to measure several valuable parameters with special reference to epithelium differentiation. METHODS:4 groups of 10 images each were selected at random from 68...

journal_title：Diagnostic pathology

authors： Jondet M,Agoli-Agbo R,Dehennin L

更新日期：2010-01-22 00:00:00

abstract：UNLABELLED:CD5-positive marginal zone B-cell lymphoma of the mucosa-associated lymphoid tissue (MALT) of the lung is very rare. An 82-year-old Japanese woman was found to have an abnormal lung shadow on chest X-ray photography, and was admitted to our hospital. Imaging modalities including X-ray photography, computed t...

journal_title：Diagnostic pathology

authors： Terada T

更新日期：2012-02-14 00:00:00

abstract：UNLABELLED:Cutaneous mast cell tumours (MCTs) are the most common skin tumours in dogs. Due to the prevalence of canine MCTs and the variable biologic behavior of this disease, accurate prognostication and a thorough understanding of MCT biology are critical for the treatment of this disease. A cytologic diagnosis of m...

journal_title：Diagnostic pathology

authors： Hosseini E,Pedram B,Bahrami AM,Moghaddam MH,Javanbakht J,Ghomi FE,Moghaddam NJ,Koohestani M,Shafiee R

更新日期：2014-01-20 00:00:00

abstract：:Intravascular large cell lymphoma is a rare subtype of extranodal large cell lymphoma characterized by the presence of neoplastic cells within the lumina of small vessels. Most cases of intravascular large cell lymphoma have a B-cell phenotype. To date, 12 cases of intravascular natural killer (NK/)/T-cell lymphoma (I...

journal_title：Diagnostic pathology

authors： Alhumidi A

更新日期：2015-07-16 00:00:00

abstract：BACKGROUND:Evaluation of core needle biopsies (CNB) is a standard procedure for the diagnosis of breast cancer. However, tissue processing and image preparation is a time- consuming procedure and instant on-site availability of high-quality images could substantially improve the efficacy of the diagnostic procedure. Co...

journal_title：Diagnostic pathology

authors： Elfgen C,Papassotiropoulos B,Varga Z,Moskovszky L,Nap M,Güth U,Baege A,Amann E,Chiesa F,Tausch C

更新日期：2019-06-15 00:00:00

abstract：BACKGROUND:Acute promyelocytic leukemia is a cytogenetically well defined entity. Nevertheless, some features observed at diagnosis are related to a worse outcome of the patients. METHODS:In a prospective study, we analyzed peripheral (PB) leukocyte count, immunophenotype, methylation status of CDKN2B, CDKN2A and TP73...

journal_title：Diagnostic pathology

authors： De Mello MR,Albuquerque DM,Pereira-Cunha FG,Albanez KB,Pagnano KB,Costa FF,Metze K,Lorand-Metze I

更新日期：2012-06-28 00:00:00

abstract：BACKGROUND:70-80% of sporadic endometrial carcinomas are defined as endometrioid carcinoma (EC). Early-stage, well differentiated endometrial carcinomas usually retain expression of estrogen and progesterone receptors (ER and PR, respectively), as advanced stage, poorly differentiated tumors often lack one or both of t...

journal_title：Diagnostic pathology

authors： Kreizman-Shefer H,Pricop J,Goldman S,Elmalah I,Shalev E

更新日期：2014-03-31 00:00:00

abstract：BACKGROUND:The optimal course of clinical follow-up after a diagnosis of breast papillary lesion on a core needle biopsy (CNB) remains elusive. In particular, no reports in literature have addressed this question in African-American population. We describe our experience with breast papillary lesions in a primarily Afr...

journal_title：Diagnostic pathology

authors： Wang H,Tsang P,D'Cruz C,Clarke K

更新日期：2014-04-24 00:00:00

abstract：BACKGROUND:The polymorphism Pro12Ala in peroxisome proliferator-activated receptor-γ2 gene (PPARγ2) has been reported to be associated with diabetic nephropathy (DN) in some studies, though the results remain inconclusive. To explore this relationship between PPARγ2 Pro12Ala polymorphism and the susceptibility for DN, ...

journal_title：Diagnostic pathology

authors： Wang L,Teng Z,Cai S,Wang D,Zhao X,Yu K

更新日期：2013-07-15 00:00:00

abstract：UNLABELLED:Seven percent of renal cell carcinoma (RCC) cases are diagnosed as "unclassified" RCC by morphology. Genetic profiling of RCCs helps define renal tumor subtypes, especially in cases where morphologic diagnosis is inconclusive. This report describes a patient with synchronous clear cell RCC (ccRCC) and a tubu...

journal_title：Diagnostic pathology

authors： Quiroga-Garza G,Piña-Oviedo S,Cuevas-Ocampo K,Goldfarb R,Schwartz MR,Ayala AG,Monzon FA

更新日期：2012-02-27 00:00:00

abstract：BACKGROUND:To distinguish between malignant and benign lesions of the thyroid gland histological demonstration is often required since the fine-needle aspiration biopsy method applied pre-operatively has some limitations. In an attempt to improve diagnostic accuracy, markers using immunocytochemistry and immunohistoche...

journal_title：Diagnostic pathology

authors： de Matos LL,Del Giglio AB,Matsubayashi CO,de Lima Farah M,Del Giglio A,da Silva Pinhal MA

更新日期：2012-08-13 00:00:00

abstract：:Giant cell tumor (GCT) of bone is a locally destructive tumor that occurs predominantly in long bones of post-pubertal adolescents and young adults, where it occurs in the epiphysis. The majority are treated by aggressive curettage or resection. Vascular invasion outside the boundary of the tumor can be seen. Metastas...

journal_title：Diagnostic pathology

authors： Miller IJ,Blank A,Yin SM,McNickle A,Gray R,Gitelis S

更新日期：2010-09-22 00:00:00

abstract：BACKGROUND:Glomus tumors typically occur in the subcutaneous tissue of distal extremities, but rarely in visceral organs. Most glomus tumors are benign, while others have been reported to have malignant potential. Herein, a unique case of a liver glomus tumor with atypical histological features is reported. CASE PRESE...

journal_title：Diagnostic pathology

authors： Hirose K,Matsui T,Nagano H,Eguchi H,Marubashi S,Wada H,Morii E

更新日期：2015-07-19 00:00:00

abstract：:Two studies recently reported around 10% of EGFR activating mutations in triple negative breast cancers from Asian patients. However, we did not find any EGFR activating mutation in a series of 229 breast tumor samples from European patients. Like in lung cancer, the EGFR mutation profiles seem to be related to the et...

journal_title：Diagnostic pathology

authors： Lamy PJ,Jacot W

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Ki67 is currently the proliferation biomarker of choice, with both prognostic and predictive value in breast cancer. A lack of consensus regarding Ki67 use in pre-analytical, analytical and post-analytical practice may hinder its formal acceptance in the clinical setting. METHODS:One hundred breast cancer s...

journal_title：Diagnostic pathology

authors： Romero Q,Bendahl PO,Fernö M,Grabau D,Borgquist S

更新日期：2014-06-16 00:00:00

abstract：BACKGROUND:Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death worldwide, mainly due to its high rates of postoperative recurrence and metastasis. Please remove, it currently ranks as the third most common cause of cancer-related deaths. MiRNAs are a set of small, single-stranded, non-coding RNA m...

journal_title：Diagnostic pathology

authors： Ajdarkosh H,Dadpay M,Yahaghi E,Pirzaman ER,Fayyaz AF,Darian EK,Mokarizadeh A

更新日期：2015-08-07 00:00:00