Synchronous clear cell renal cell carcinoma and tubulocystic carcinoma: genetic evidence of independent ontogenesis and implications of chromosomal imbalances in tumor progression.

abstract：BACKGROUND:The feasibility of evaluating an objective grading of cervical intraneoplasia lesions (CIN) is attempted using an automatic computerized system able to measure several valuable parameters with special reference to epithelium differentiation. METHODS:4 groups of 10 images each were selected at random from 68...

journal_title：Diagnostic pathology

authors： Jondet M,Agoli-Agbo R,Dehennin L

更新日期：2010-01-22 00:00:00

abstract：BACKGROUND:Discordant lymphoma is defined by the simultaneous presence of two or more distinct types of lymphomas at different anatomic sites. With fewer than 20 studies reporting cases of discordant lymphoma to date, the incidence of this condition is believed to be very low. CASE PRESENTATION:Here, we report a case ...

journal_title：Diagnostic pathology

authors： Zhang C,Yi Y,Chen C,Wang J,Liu Z

更新日期：2015-12-29 00:00:00

abstract：:Arrhythmogenic right ventricular cardiomyopathy (ARVC) is characterized by recurrent coma, ventricular tachycardias and the replacement of the myocardium with fatty and fibrous tissue. We described a 42-year-old female patient without clinical arrhythmias which was diagnosed as ARVC by magnetic resonance imaging (MRI)...

journal_title：Diagnostic pathology

authors： Wei J,Tang J,Xia L,Chen X,Wang DW

更新日期：2012-06-12 00:00:00

abstract：BACKGROUND:Hypermethylation of the promoter region of the RAS association domain family 1A gene (RASSF1A) occurs widely in hepatocellular carcinoma (HCC) tissues. While the diagnostic performance of the use of RASSF1A methylation as a serum or plasma marker in patients with HCC has varied largely in the literature,we c...

journal_title：Diagnostic pathology

authors： Dong X,He H,Zhang W,Yu D,Wang X,Chen Y

更新日期：2015-08-04 00:00:00

abstract：BACKGROUND:Several studies reported the dysregulation of miR-541 in the progression of some human malignancies. Osteosarcoma (OS) is one of the most common primary malignant bone tumors. This study aimed to assess the expression and clinical significance of miR-541 in OS patients and explore the biological function of ...

journal_title：Diagnostic pathology

authors： Liu C,Yi X

更新日期：2020-07-24 00:00:00

abstract：BACKGROUND:In recent years, a battery-powered bone marrow biopsy system was developed and cleared by the U.S. Food and Drug Administration to allow health care providers to access the bone marrow space quickly and efficiently. A multicenter randomized clinical trial was designed for adult patients to determine if the p...

journal_title：Diagnostic pathology

authors： Berenson JR,Yellin O,Blumenstein B,Bojanower D,Croopnick J,Aboulafia D,Upadhyaya G,Spadaccini C

更新日期：2011-03-23 00:00:00

abstract：BACKGROUND:To evaluate the clinical utility of LIM Domain Only 2 (LMO2) negative and CD38 positive in diagnosis of Burkitt lymphoma (BL). METHODS:LMO2 and CD38 expression determined by immunohistochemistry in 75 BL, 12 High-grade B-cell lymphoma, NOS (HGBL,NOS) and 3 Burkitt-like lymphomas with the 11q aberration. RE...

journal_title：Diagnostic pathology

authors： Liu Y,Bian T,Zhang Y,Zheng Y,Zhang J,Zhou X,Xie J

更新日期：2019-09-04 00:00:00

abstract：:Central neurocytoma/extraventricular neurocytoma is a central nervous system (CNS) tumor composed of uniform round cells with neuronal differentiation. The typical lesions of central neurocytoma/extraventricular neurocytoma are at the interventricular foramen of the lateral ventricles (central neurocytoma) or brain pa...

journal_title：Diagnostic pathology

authors： Yu JH,Yang LH,Lin XY,Dai SD,Qiu XS,Wang EH

更新日期：2015-09-17 00:00:00

abstract：:A case of prenatally diagnosed, giant cord hemangioma is reported, which was accompanied by the elevation of maternal serum alpha-fetoprotein (MS-AFP) and human chorionic gonadotropin (MS-hCG) levels. A 30-year-old woman without a previous history of gravida or para, presented with intermittent abdominal pain at 26 we...

journal_title：Diagnostic pathology

authors： Hara K,Fukumura Y,Saito T,Arakawa A,Okabe H,Takeda S,Yao T

更新日期：2015-09-04 00:00:00

abstract：BACKGROUND:Primary central nervous system (CNS) diffuse large B-cell lymphoma (DLBCL) is a rare intracranial tumor, defined as DLBCL arising from the brain, spinal cord, leptomeninges and eye, with an overall annual incidence of 5 cases per million. The primary CNS anaplastic variant of DLBCL (A-DLBCL) is even less com...

journal_title：Diagnostic pathology

authors： Xu T,Jia Q,Wang Y,Liu Y,Han D,Li P,Ma J,Fan L,Yan Q,Guo S,Li M,Wang Z

更新日期：2019-05-20 00:00:00

abstract：BACKGROUND:Crystalloid podocytopathy with focal segmental glomerulosclerosis in plasma cell myeloma (PCM) is rare. CASE PRESENTATION:We present a case of crystalline deposition in the bone marrow (BM) and various renal cells with only proteinuria as a symptom. As workup for proteinuria, a renal biopsy sample was obtai...

journal_title：Diagnostic pathology

authors： Jeon YL,Lee WI,Choi Y,Kang SY,Kim MH,Lim SJ,Lee SH

更新日期：2015-12-16 00:00:00

abstract：UNLABELLED:Imaging appearance of cyst-like changes is most frequently described in primary neuroendocrine lesions, especially pancreatic NETs.The imaging finding of a pseudocystic lesion of the liver puts in differential diagnosis many pathologies such as infectious diseases, simple biliary cysts up to biliary cystaden...

journal_title：Diagnostic pathology

authors： Fiori S,Del Gobbo A,Gaudioso G,Caccamo L,Massironi S,Cavalcoli F,Bosari S,Ferrero S

更新日期：2013-09-13 00:00:00

abstract：BACKGROUND:HER2/neu overexpression and/or amplification has been widely studied in a number of solid tumors, primarily in the breast. In gynecologic neoplasms, determination of HER2/neu status has not been well studied as a predictive biomarker in anti-HER2/neu treatment. METHODS:We systematically evaluated the HER2/n...

journal_title：Diagnostic pathology

authors： Woo JS,Apple SK,Sullivan PS,Rao JY,Ostrzega N,Moatamed NA

更新日期：2016-10-22 00:00:00

abstract：UNLABELLED:Giant cell angioblastoma (GCAB) is an extremely rare soft tissue tumor of early childhood and only five cases have been described to date. As such the clinical, pathological, and prognostic features are poorly defined. We prensent here a new case of GCAB in bone of a child aged 4-years old. The lesion was co...

journal_title：Diagnostic pathology

authors： Mao RJ,Jiang ZM,Zhang HZ,Zhu XZ,Zhang QL

更新日期：2012-08-29 00:00:00

abstract：:Tumours of ovarian-epithelial type of the testis, including serous borderline tumours, represent very rare entities. They are identical to the surface epithelial tumours of the ovary and have been reported in patients from 14 to 68 years of age. We describe two cases of a 46- and a 39-year old man with incidental find...

journal_title：Diagnostic pathology

authors： Bürger T,Schildhaus HU,Inniger R,Hansen J,Mayer P,Schweyer S,Radzun HJ,Ströbel P,Bremmer F

更新日期：2015-07-22 00:00:00

abstract：BACKGROUND:Human kallikrein gene 6 (KLK6) is a member of the human kallikrein gene family (Kallikreins, KLKs). Human kallikrein-related peptidase 6 (hK6) is a trypsin-like serine protease encoded by the KLK6, has been reported to be highly expressed in several cancers including gastric cancer. In this study, we investi...

journal_title：Diagnostic pathology

authors： Liu X,Xiong H,Li J,He Y,Yuan X

更新日期：2013-04-15 00:00:00

abstract：BACKGROUND:This study is to investigate the expression of progranulin (PGRN) in systemic lupus erythematosus (SLE) patients and the effect of glucocorticoid (GC) treatment on its expression. METHODS:Thirty newly diagnosed severe SLE patients and 30 healthy subjects were enrolled in this study. The serum levels of PGRN...

journal_title：Diagnostic pathology

authors： Qiu F,Song L,Ding F,Liu H,Shu Q,Yang N,Liu W,Li X

更新日期：2013-05-23 00:00:00

abstract：BACKGROUND:Although often associated with holoprosencephaly, little detail of the histopathology of cyclopia is available. Here, we describe the ocular findings in a case of trisomy 13 to better understand the histogenesis of the rosettes, or tubules, characteristic of the retinal dysplasia associated with this conditi...

journal_title：Diagnostic pathology

authors： Chan A,Lakshminrusimha S,Heffner R,Gonzalez-Fernandez F

更新日期：2007-12-18 00:00:00

abstract：:This study examined the effect of tissue section thickness and consistency--parameters outside the direct control of the imaging devices themselves--on WSI capture speed and image quality. Preliminary data indicates that thinner, more consistent tissue sectioning (such as those produced by automated tissue sectioning ...

journal_title：Diagnostic pathology

authors： Yagi Y,Gilbertson JR

更新日期：2008-07-15 00:00:00

abstract：BACKGROUND:Evaluation of core needle biopsies (CNB) is a standard procedure for the diagnosis of breast cancer. However, tissue processing and image preparation is a time- consuming procedure and instant on-site availability of high-quality images could substantially improve the efficacy of the diagnostic procedure. Co...

journal_title：Diagnostic pathology

authors： Elfgen C,Papassotiropoulos B,Varga Z,Moskovszky L,Nap M,Güth U,Baege A,Amann E,Chiesa F,Tausch C

更新日期：2019-06-15 00:00:00

abstract：BACKGROUND:The aim of this study was to investigate how differences in expression of HER2 between primary gastric cancers (PGCs) and their corresponding metastatic lymph nodes (LMNs) might affect its potential as a prognostic indicator in treatments including anti-HER2 agents. METHODS:The analysis was conducted in 102...

journal_title：Diagnostic pathology

authors： Kochi M,Fujii M,Masuda S,Kanamori N,Mihara Y,Funada T,Tamegai H,Watanabe M,Suda H,Takayama T

更新日期：2013-11-21 00:00:00

abstract：BACKGROUND:The optimal course of clinical follow-up after a diagnosis of breast papillary lesion on a core needle biopsy (CNB) remains elusive. In particular, no reports in literature have addressed this question in African-American population. We describe our experience with breast papillary lesions in a primarily Afr...

journal_title：Diagnostic pathology

authors： Wang H,Tsang P,D'Cruz C,Clarke K

更新日期：2014-04-24 00:00:00

abstract：:Primary pleural angiosarcoma is a rare and clinically aggressive tumor. Patients usually present with chest pain, dyspnea, hemoptysis and/or cough. Radiologic studies reveal diffuse pleural thickening and pleural effusion with or without mass lesion. The clinical and radiological features both resemble those of mesoth...

journal_title：Diagnostic pathology

authors： Kao YC,Chow JM,Wang KM,Fang CL,Chu JS,Chen CL

更新日期：2011-12-30 00:00:00

abstract：BACKGROUND:Mesonephric-like adenocarcinoma (M-LAC) is a rare, recently described tumor occurring in the uterine corpus and ovary, which shares the same morphological and immunohistochemical features with the more common mesonephric adenocarcinoma (MAC), which mostly arises the uterine cervix. Despite the similarities b...

journal_title：Diagnostic pathology

authors： Dundr P,Gregová M,Němejcová K,Bártů M,Hájková N,Hojný J,Stružinská I,Fischerová D

更新日期：2020-07-21 00:00:00

abstract：BACKGROUND:The association between the Val158Met polymorphism in the catechol-O-methyltransferase (COMT) gene and lung cancer risk remains controversial and inconclusive. Therefore, the meta-analysis was performed to provide a quality reevaluation of the association between the COMT Val158Met polymorphism and the risk ...

journal_title：Diagnostic pathology

authors： Tan X,Chen M

更新日期：2014-10-04 00:00:00

abstract：:Perivascular epithelioid cell tumor (PEComa) is a rare entity originating from mesenchymal tissue, which stains for both melanocytic and smooth muscle markers. We would like to present an unusual case of the PEComa of the mesentery which was unexpected discovery in a female patient with colonic adenocarcinoma. The tum...

journal_title：Diagnostic pathology

authors： Wejman J,Nowak K,Gielniewska L,Komorowska M,Dąbrowski W

更新日期：2015-04-18 00:00:00

abstract：BACKGROUND:The development of inhibitors against factor 8 (F8) is the most serious complication of replacement therapy with F8 in children with severe hemophilia. It was suggested that mismatched F8 replacement therapy may be a risk factor for the development of anti-factor F8 alloantibodies. Recently four single nucle...

journal_title：Diagnostic pathology

authors： Elmahmoudi H,Belhedi N,Jlizi A,Zahra K,Meddeb B,Ben Ammar Elgaaied A,Gouider E

更新日期：2011-06-17 00:00:00

abstract：BACKGROUND:Rhabdoid colorectal tumor (RCT) is a rare, highly aggressive neoplasm recurrent in elderly patients, commonly at the caecum. The molecular mechanisms underlying RCT pathogenesis remain poorly elucidated. The differential diagnosis is with the malignant rhabdoid tumors of infancy characterized by genetic inac...

journal_title：Diagnostic pathology

authors： Pancione M,Remo A,Sabatino L,Zanella C,Votino C,Fucci A,Di Blasi A,Lepore G,Daniele B,Fenizia F,Molinari E,Normanno N,Manfrin E,Vendraminelli R,Colantuoni V

更新日期：2013-02-20 00:00:00

abstract：BACKGROUND:Branchial cleft anomalies constitute a frequently encountered and commonly non-lethal disease in otolaryngology, and result from aberrant embryonic development. The third branchial cleft fistula is one of the four known specific types of branchial cleft anomalies, and always presents as recurrent neck absces...

journal_title：Diagnostic pathology

authors： Tong F,Liang Y,Khan MF,Zhang L,Li W,Mahmoodurrahman M,Zhou Y

更新日期：2016-09-15 00:00:00

abstract：BACKGROUND/OBJECTIVE:Metastatic adenocarcinoma from an unknown primary site is a common clinical problem. Determining the cytokeratin (CK) 7/CK20 pattern of tumors is one of the most helpful procedures for this purpose since the CK7-/CK20+ pattern is typical of colorectal adenocarcinomas. CDX2, a critical nuclear trans...

journal_title：Diagnostic pathology

authors： Bayrak R,Haltas H,Yenidunya S

更新日期：2012-01-23 00:00:00