Abstract:
BACKGROUND:Visceral adiposity contributes to cardiometabolic risk, and visceral adiposity index (VAI) had significant correlation with visceral adiposity. We aimed to explore whether VAI was associated with cardiac structure and function and assess the impact of the cut-off points of VAI defining visceral adipose dysfunction (VAD) on the severity of coronary heart disease (CHD). METHODS:A total of 95 patients with CHD were divided into Control (nondiabetic CHD patients) and DM group (diabetic CHD patients). Then the two groups were respectively divided into VAD absent and VAD groups. Clinical, echocardiographic and coronary artery angiographic indexes were acquired to examine in relation to VAI. RESULTS:A significant increasing trend among the four groups of patients (Control + VAD absent, Control +VAD, DM + VAD absent and DM +VAD groups) were observed for waist circumference (WC), body mass index (BMI), systolic blood pressure (SBP), glucose, VAI and Gensini score (P<0.05 for all). The following variables were associated with VAI: total cholesterol, nonesterified fatty acid, Waist-Hip ratio and SBP. VAI was independently associated with Gensini score. CONCLUSIONS:The extent of CHD was more severe in diabetes, and VAI as a simple indicator of visceral adipose mass was strongly associated with the severity of CHD. The cut-off points of VAI used for defining VAD were more useful in diabetic CHD patients in identifying the severity of CHD.
journal_name
Diabetol Metab Syndrjournal_title
Diabetology & metabolic syndromeauthors
Han L,Fu KL,Zhao J,Wang ZH,Tang MX,Wang J,Wang H,Zhang Y,Zhang W,Zhong Mdoi
10.1186/1758-5996-6-143subject
Has Abstractpub_date
2014-12-22 00:00:00pages
143issue
1issn
1758-5996pii
393journal_volume
6pub_type
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