Albumin binding ligands and albumin conjugate uptake by cancer cells.

abstract：Background:The association of diabetic nephropathy (DN) risk with single nucleotide polymorphisms (SNPs) within Engulfment and Cell Motility 1 (ELMO1) gene and gene-environment synergistic effect have not been extensively examined in, therefore, the purpose of this study is to explore the association between multiple S...

journal_title：Diabetology & metabolic syndrome

authors： Hou Y,Gao Y,Zhang Y,Lin ST,Yu Y,Yang L

更新日期：2019-11-27 00:00:00

abstract：BACKGROUND:Dietary factors are important environmental factors associated with the prevalence of metabolic syndrome (MS). The objective of this study was to assess the habitual nutrient intakes of patients with MS. METHODS:A cross-sectional study included 103 patients (82 % women) with MS seen at the endocrinology out...

journal_title：Diabetology & metabolic syndrome

authors： da Cunha AT,Pereira HT,de Aquino SL,Sales CH,Sena-Evangelista KC,Lima JG,Lima SC,Pedrosa LF

更新日期：2016-04-14 00:00:00

abstract：UNLABELLED: BACKGROUND:Achieving good glycemic control is of paramount importance in the reduction of diabetes mellitus (DM) associated morbidity and mortality. Insulin plays a key role in the management of DM but unfortunately whilst some healthcare providers present insulin as a treatment of last resort , patients o...

journal_title：Diabetology & metabolic syndrome

authors： Ogbera AO,Kuku SF

更新日期：2012-12-02 00:00:00

abstract：Objective:Several controversial findings have been reported on treatment outcomes for diabetic stroke patients that received thrombolysis therapy in the hospital. We determined whether the association between telestroke technology, thrombolysis therapy and clinical risk factors in diabetic acute ischemic stroke may res...

journal_title：Diabetology & metabolic syndrome

authors： Nathaniel TI,Ubah C,Wormack L,Gainey J

更新日期：2019-05-09 00:00:00

abstract：BACKGROUND:Many patients with chronic heart failure (CHF) are believed to have unrecognized diabetes, which is associated with a worse prognosis. This study aimed to describe glucose tolerance in a general stable CHF population and to identify determinants of glucose tolerance focusing on body composition and skeletal ...

journal_title：Diabetology & metabolic syndrome

authors： Stevens AL,Hansen D,Vandoren V,Westerlaken R,Creemers A,Eijnde BO,Dendale P

更新日期：2014-03-27 00:00:00

abstract：Purpose:People with obesity have a compromised browning capacity of adipose tissue when faced with sympathetic stimuli. This study aimed to determine whether norepinephrine treatment can enhance the induction of precursor cells from human white adipose tissue to differentiate into adipocytes that express key markers of...

journal_title：Diabetology & metabolic syndrome

authors： Qiu Y,Sun L,Hu X,Zhao X,Shi H,Liu Z,Yin X

更新日期：2020-10-22 00:00:00

abstract：BACKGROUND:Adipokines, e.g. TNFα, IL-6 and leptin increase insulin resistance, and consequent hyperinsulinaemia influences breast cancer progression. Beside its mitogenic effects, insulin may influence adipokine production from adipocyte stromal cells and paracrine enhancement of breast cancer cell growth. In contrast,...

journal_title：Diabetology & metabolic syndrome

authors： Grisouard J,Dembinski K,Mayer D,Keller U,Müller B,Christ-Crain M

更新日期：2011-07-20 00:00:00

abstract：Background:The present study identified whether glycemic variability (GV) was associated with vascular calcification and explored the underlying mechanisms. Methods:Eighty-four consecutive type 2 diabetic patients with unstable angina (UA) were included from January 2018 to June 2018 to calculate calcification scores ...

journal_title：Diabetology & metabolic syndrome

authors： Zhang L,Sun H,Liu S,Gao J,Xia J

更新日期：2019-08-19 00:00:00

abstract：BACKGROUND:Type 1 diabetes mellitus in pregnant women is associated with an increased risk of congenital malformations, obstetric complications, neonatal morbidity, and mortality. Our aim was to evaluate which factors from the first trimester of pregnancy have a significant impact on the pregnancy outcomes of women wit...

journal_title：Diabetology & metabolic syndrome

authors： Timar B,Timar R,Albai A,Stoian D,Nitu R,Craina M

更新日期：2014-11-22 00:00:00

abstract：Background:The role of serum fibroblast growth factor 19 (FGF19) in arteriosclerosis is not well known. In the present study, we aimed to explore whether serum FGF19 levels were related to arteriosclerosis parameters, including arterial stiffness and atherogenic index of plasma (AIP), in patients with type 2 diabetes (...

journal_title：Diabetology & metabolic syndrome

authors： Liu WS,Tang MJ,Xu TL,Su JB,Wang XQ,Xu F,Zhang DM,Zhu Q,Cao J,Wang H

更新日期：2020-05-20 00:00:00

abstract：BACKGROUND:Galectin-3 is a family of soluble beta-galactoside-binding lectins that play many important regulatory roles in inflammation. Galectin-3-deficient mice have been shown to exhibit excess adiposity, hyperglycemia, insulin resistance and systemic inflammation. We investigated the association between serum galec...

journal_title：Diabetology & metabolic syndrome

authors： Ohkura T,Fujioka Y,Nakanishi R,Shiochi H,Sumi K,Yamamoto N,Matsuzawa K,Izawa S,Ohkura H,Ueta E,Kato M,Miyoshi E,Taniguchi S,Yamamoto K

更新日期：2014-09-27 00:00:00

abstract：Background:To investigate the association of low carbohydrate diet (LCD) score with the risk of type 2 diabetes among adults. Methods:This cohort study was conducted on 4356 healthy participants aged ≥ 19 years old, who were followed-up for a mean duration of 3 years within the framework of the Tehran Lipid and Glucos...

journal_title：Diabetology & metabolic syndrome

authors： Sali S,Farhadnejad H,Asghari G,Teymoori F,Mirmiran P,Djazayeri A,Azizi F

更新日期：2020-10-07 00:00:00

abstract：BACKGROUND:Increased carotid intima-media thickness (CIMT), a marker of subclinical atherosclerosis, is an independent predictor of future cardiovascular events, and has been reported in children with various chronic diseases, including type 1 diabetes mellitus (DM1). OBJECTIVES:Evaluate CIMT and its association with ...

journal_title：Diabetology & metabolic syndrome

authors： Fusaro MF,Zanini JL,Silva IN

更新日期：2016-11-11 00:00:00

abstract：BACKGROUND:Non-alcoholic steatohepatitis (NASH) is highly associated with metabolic syndrome, a major cause of morbidity in the globalized society. The renin-angiotensin system (RAS) influences hepatic fatty acid metabolism, inflammation and fibrosis. Thus, in the present study, we aimed to evaluate the effect of alisk...

journal_title：Diabetology & metabolic syndrome

authors： Ramalho FN,Sanches SC,Foss MC,Augusto MJ,Silva DM,Oliveira AM,Ramalho LN

更新日期：2017-10-13 00:00:00

abstract：Background:Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in patients with type 2 diabetes (T2DM). Carotid intima-media thickness (CIMT) is considered a preclinical stage of atherosclerosis. Therefore, it is necessary to identify the related risk factors for CIMT to facilitate the early pr...

journal_title：Diabetology & metabolic syndrome

authors： Zhou YY,Qiu HM,Yang Y,Han YY

更新日期：2020-01-28 00:00:00

abstract：Background:Vitamins are essential micronutrients with antioxidant potential that may provide a complementary treatment for patients with chronic diseases. Our aim was to assess the effect of vitamin supplementation on the antioxidant status and glycemic index of type 2 diabetes mellitus patients. Methods:We performed ...

journal_title：Diabetology & metabolic syndrome

authors： Balbi ME,Tonin FS,Mendes AM,Borba HH,Wiens A,Fernandez-Llimos F,Pontarolo R

更新日期：2018-03-14 00:00:00

abstract：BACKGROUND:Using patient data from the GetGoal-Duo1, -L, and L-Asia trials, the objectives of this study were to evaluate and compare the impact of lixisenatide once-daily add-on treatment to basal insulin therapy ±oral antidiabetic drugs (OADs) among type 2 diabetes (T2DM) patients subdivided into groups, based on the...

journal_title：Diabetology & metabolic syndrome

authors： Eto K,Naito Y,Seino Y

更新日期：2015-11-21 00:00:00

abstract：: In recent decades, Diabetes Mellitus has become a severe and growing global public healthcare problem due to the increase of its prevalence, morbidity and mortality. Post-transplant diabetes mellitus (PTDM) is a complication which takes place after a solid organ transplant, and its incidence is widely variable, rangi...

journal_title：Diabetology & metabolic syndrome

authors： Gomes MB,Cobas RA

更新日期：2009-10-05 00:00:00

abstract：BACKGROUND:Pregnant women with mild gestational hyperglycemia present a high risk for hypertension and obesity, and appear to reproduce the model of metabolic syndrome in pregnancy, including hyperinsulinemia and insulin resistance. Diabetic patients have a higher frequency of the IRS-1 Gly972Arg variant and this polym...

journal_title：Diabetology & metabolic syndrome

authors： Gelaleti RB,Damasceno DC,Salvadori DM,Marcondes JP,Lima PH,Morceli G,Calderon IM,Rudge MV

更新日期：2015-04-02 00:00:00

abstract：:The development of extended-action insulin analogues was motivated by the unfavorable pharmacokinetic (PK) profile of the conventional long-acting insulin formulations, generally associated with marked inter and intra patient variability and site- and dose-dependent effect variation. The new ultra-long insulin analogu...

journal_title：Diabetology & metabolic syndrome

authors： Tambascia MA,Eliaschewitz FG

更新日期：2015-06-26 00:00:00

abstract：BACKGROUND:In mammals, the temperature rhythm is regulated by the circadian pacemaker located in the suprachiasmatic nuclei, and is considered a "marker rhythm". Melatonin, the pineal gland hormone, is a major regulator of the endogenous rhythms including body temperature. Its production is influenced by many factors, ...

journal_title：Diabetology & metabolic syndrome

authors： Ramos-Lobo AM,Buonfiglio DC,Cipolla-Neto J

更新日期：2015-04-29 00:00:00

abstract：BACKGROUND:Many self-management programs have been developed so far. Their effectiveness varies. The program 'Beyond Good Intentions' (BGI) is based on proactive coping and has proven to be (cost-) effective in achieving reductions in BMI and blood pressure in screen-detected type 2 diabetes patients up until nine mont...

journal_title：Diabetology & metabolic syndrome

authors： Vos RC,Eikelenboom NW,Klomp M,Stellato RK,Rutten GE

更新日期：2016-12-20 00:00:00

abstract：BACKGROUND:Evidences support the benefits of moderate- to high-intensity statins for patients with acute myocardial infarction (AMI) except for those with type 2 diabetes mellitus (T2DM) on dialysis after AMI. This study was aimed to investigate the safety and efficacy of secondary prevention of cardiovascular diseases...

journal_title：Diabetology & metabolic syndrome

authors： Li YR,Tsai SS,Lin YS,Chung CM,Chen ST,Sun JH,Liou MJ,Chen TH

更新日期：2017-09-19 00:00:00

abstract：BACKGROUND:Long QT interval (QT) and abnormal QT dispersion (QTd) are associated with sudden death. The relationship between cardiac autonomic neuropathy (CAN) and QT indices in type 2 diabetic patients were investigated. METHODS:Totally 130 diabetic subjects (mean age 50.87 ± 13.9 years) were included (70 individuals...

journal_title：Diabetology & metabolic syndrome

authors： Vasheghani M,Sarvghadi F,Beyranvand MR,Emami H

更新日期：2020-11-19 00:00:00

abstract：Background:Exercise can disrupt homeostasis and trigger many adaptive responses in different hormonal axes. The study of hormonal interactions with physical activity is highly complex due to the number of variables, such as exercise duration, exercise intensity, individual level of training, circadian rhythm, nutrition...

journal_title：Diabetology & metabolic syndrome

authors： de Souza HS,Jardim TV,Barroso WKS,de Oliveira Vitorino PV,Souza ALL,Jardim PCV

更新日期：2019-02-15 00:00:00

abstract：BACKGROUND:The objective was to evaluate the muscle glucose metabolism in rats fed a fructose-rich diet after fetal protein malnutrition, at rest and after acute physical exercise at maximal lactate steady-state intensity. METHODS:The male offspring born of mothers fed on a balanced or low-protein diet were split in f...

journal_title：Diabetology & metabolic syndrome

authors： Cambri LT,Ribeiro C,Botezelli JD,Ghezzi AC,Mello MA

更新日期：2014-11-06 00:00:00

abstract：UNLABELLED: BACKGROUND:Plant flavonoids are emerging as potent therapeutic drugs effective against a wide range of aging diseases particularly bone metabolic disorders. Morin (3,5,7,20,40-pentahydroxyflavone), a member of flavonols, is an important bioactive compound by interacting with nucleic acids, enzymes and prot...

journal_title：Diabetology & metabolic syndrome

authors： Abuohashish HM,Al-Rejaie SS,Al-Hosaini KA,Parmar MY,Ahmed MM

更新日期：2013-02-06 00:00:00

abstract：BACKGROUND:The aim of this study is to compare the efficacy of intensification of insulin treatment with insulin glargine and biphasic human insulin in patients with type 2 diabetes on concomitant therapy with oral antidiabetic drugs (OAD) in daily clinical practice. METHODS:A retrospective multicentre parallel two-ar...

journal_title：Diabetology & metabolic syndrome

authors： Tentolouris N,Kyriazopoulou V,Makrigiannis D,Baroutsou B

更新日期：2013-08-05 00:00:00

abstract：BACKGROUND:Angiotensin-converting enzyme (ACE) inhibitors are widely prescribed for patients with diabetes as a nephroprotector drug or to treat hypertension. Generally they are safe for clinical practice, but the relationship between these drugs and angioedema is known. The exact mechanism for ACE inhibitors-induced a...

journal_title：Diabetology & metabolic syndrome

authors： Alencar RC,Cobas RA,Gomes MB

更新日期：2010-01-20 00:00:00

abstract：BACKGROUND:Helicobacter pylori (H. pylori) infection is reported to be associated with various extragastrointestinal conditions such as insulin resistance, diabetes mellitus and metabolic syndrome. H. pylori infection and type 2 diabetes mellitus (T2DM) are associated with oxidative stress, this cross-relation between ...

journal_title：Diabetology & metabolic syndrome

authors： Nasif WA,Mukhtar MH,Nour Eldein MM,Ashgar SS

更新日期：2016-05-03 00:00:00