Antioxidant effects of vitamins in type 2 diabetes: a meta-analysis of randomized controlled trials.

abstract：Background:Adipokines are involved in the pathogenesis of metabolic disorders including obesity and type 2 diabetes mellitus (T2DM). This study investigates the levels of leptin, resistin, visfatin, secreted frizzled-related protein 5 (SFRP5), monocyte chemoattractant protein-1 (MCP-1) and retinol-binding protein 4 (RB...

journal_title：Diabetology & metabolic syndrome

authors： Toan NL,Van Hoan N,Cuong DV,Dung NV,Dung PT,Hang NT,Dieu DTH,Chung DT,Son HA,Phong PX,Lenon GB,Van De D,Van Tong H

更新日期：2018-05-15 00:00:00

abstract：BACKGROUND:The single-center, open-label, four-arm, exploratory study investigates the relation of different anti-diabetics to serum levels of active TGF-β, a known pro-fibrotic stimulus, before and after a defined test meal. FINDINGS:We investigated sera of patients with type 2 diabetes mellitus (T2DM) treated with m...

journal_title：Diabetology & metabolic syndrome

authors： Pscherer S,Freude T,Forst T,Nussler AK,Braun KF,Ehnert S

更新日期：2013-08-31 00:00:00

abstract：BACKGROUND:Many self-management programs have been developed so far. Their effectiveness varies. The program 'Beyond Good Intentions' (BGI) is based on proactive coping and has proven to be (cost-) effective in achieving reductions in BMI and blood pressure in screen-detected type 2 diabetes patients up until nine mont...

journal_title：Diabetology & metabolic syndrome

authors： Vos RC,Eikelenboom NW,Klomp M,Stellato RK,Rutten GE

更新日期：2016-12-20 00:00:00

abstract：BACKGROUND:Asymmetric dimethylarginine (ADMA) is an endogenous competitive inhibitor of nitric oxide (NO) synthetase. Elevated ADMA reduces NO formation and is associated with endothelial dysfunction. The aims of this study were to evaluate endothelial function and the cardiovascular risk (CVR) profile in patients with...

journal_title：Diabetology & metabolic syndrome

authors： Sayki Arslan M,Turhan S,Dincer I,Mizrak D,Corapcioglu D,Idilman R

更新日期：2014-10-14 00:00:00

abstract：BACKGROUND:Dietary factors are important environmental factors associated with the prevalence of metabolic syndrome (MS). The objective of this study was to assess the habitual nutrient intakes of patients with MS. METHODS:A cross-sectional study included 103 patients (82 % women) with MS seen at the endocrinology out...

journal_title：Diabetology & metabolic syndrome

authors： da Cunha AT,Pereira HT,de Aquino SL,Sales CH,Sena-Evangelista KC,Lima JG,Lima SC,Pedrosa LF

更新日期：2016-04-14 00:00:00

abstract：Objectives:To evaluate the effect of Lactobacillus casei 01 on dietary intake, body weight, and glycemic control in patients with T2DM. Method:Forty patients with T2DM (n = 20 for each group) were assigned into two groups in present trial. The patients in the probiotic group received a daily capsule containing a minim...

journal_title：Diabetology & metabolic syndrome

authors： Khalili L,Alipour B,Asghari Jafarabadi M,Hassanalilou T,Mesgari Abbasi M,Faraji I

更新日期：2019-01-15 00:00:00

abstract：BACKGROUND:We investigated the influence of aerobic capacity on the improvement in glycemic control achieved by long-term aerobic exercise in type 2 diabetes. METHODS:Fifty-three male patients with type 2 diabetes, recruited from outpatient clinics, wore multiple-memory accelerometers and were instructed to exercise a...

journal_title：Diabetology & metabolic syndrome

authors： Nojima H,Yoneda M,Watanabe H,Yamane K,Kitahara Y,Sekikawa K,Yamamoto H,Yokoyama A,Hattori N,Kohno N,Hiroshima University Health Promotion Study group.

更新日期：2017-08-18 00:00:00

abstract：BACKGROUND:Polymorphisms in genes encoding adiponectin (ADIPOQ) and interleukin-6 (IL6) have been associated with adiposity and obese-related phenotypes. This study investigated the relationship of ADIPOQ and IL6 gene polymorphisms with pro-inflammatory and cardiometabolic markers in obese patients. METHODS:Anthropome...

journal_title：Diabetology & metabolic syndrome

authors： de Oliveira R,Moraes TI,Cerda A,Hirata MH,Fajardo CM,Sousa MC,Dorea EL,Bernik MM,Hirata RD

更新日期：2015-04-11 00:00:00

abstract：BACKGROUND:Non-alcoholic steatohepatitis (NASH) is highly associated with metabolic syndrome, a major cause of morbidity in the globalized society. The renin-angiotensin system (RAS) influences hepatic fatty acid metabolism, inflammation and fibrosis. Thus, in the present study, we aimed to evaluate the effect of alisk...

journal_title：Diabetology & metabolic syndrome

authors： Ramalho FN,Sanches SC,Foss MC,Augusto MJ,Silva DM,Oliveira AM,Ramalho LN

更新日期：2017-10-13 00:00:00

abstract：Background:Several studies suggest that statin may increase the risk of new-onset diabetes mellitus (NODM). This study aimed to evaluate the association between the duration and recent use of statin, and the risk of NODM, based on population-based data sets. Methods:We used the South Korean National Health Insurance S...

journal_title：Diabetology & metabolic syndrome

authors： Kim DW,Kim DH,Park JH,Choi M,Kim S,Kim H,Seul DE,Park SG,Jung JH,Han K,Park YG

更新日期：2019-04-22 00:00:00

abstract：Background:Diabetic nephropathy (DN) or diabetic kidney disease refers to the deterioration of kidney function seen in chronic type 1 and type 2 diabetes mellitus patients. The progression of the disease is known to occur in a series of stages and is linked to glycemic and blood pressure control. However, despite aggre...

journal_title：Diabetology & metabolic syndrome

authors： Sulaiman MK

更新日期：2019-01-23 00:00:00

abstract：AIMS:In a population at risk for type 2 diabetes (T2DM), we assessed early physical and metabolic markers that predict progression from normal to impaired glucose tolerance (IGT) and T2DM. METHODS:A total of 388 individuals (22% male, age 46 + 11 years) at risk for T2DM were randomized to Standard (n = 182) or Interve...

journal_title：Diabetology & metabolic syndrome

authors： Leite SA,Anderson RL,Kendall DM,Monk AM,Bergenstal RM

更新日期：2009-09-16 00:00:00

abstract：Background:The present study identified whether glycemic variability (GV) was associated with vascular calcification and explored the underlying mechanisms. Methods:Eighty-four consecutive type 2 diabetic patients with unstable angina (UA) were included from January 2018 to June 2018 to calculate calcification scores ...

journal_title：Diabetology & metabolic syndrome

authors： Zhang L,Sun H,Liu S,Gao J,Xia J

更新日期：2019-08-19 00:00:00

abstract：Objective:Several controversial findings have been reported on treatment outcomes for diabetic stroke patients that received thrombolysis therapy in the hospital. We determined whether the association between telestroke technology, thrombolysis therapy and clinical risk factors in diabetic acute ischemic stroke may res...

journal_title：Diabetology & metabolic syndrome

authors： Nathaniel TI,Ubah C,Wormack L,Gainey J

更新日期：2019-05-09 00:00:00

abstract：BACKGROUND AND AIM:A low-grade inflammation is associated with cardiac autonomic neuropathy (CAN) and increased concentration of leukotriene B4 (LTB4) was found in individuals with type 1 diabetes and definitive CAN. This cross-sectional study evaluated plasma concentration of LTB4 and of other inflammatory mediators, ...

journal_title：Diabetology & metabolic syndrome

authors： Neves JAJ,De Matos MR,Ramalho T,Santos-Bezerra DP,Cavalcante CDGD,Alpino Peixoto R,Queiroz MS,Jancar S,Correa-Giannella ML

更新日期：2020-11-12 00:00:00

abstract：Purpose:People with obesity have a compromised browning capacity of adipose tissue when faced with sympathetic stimuli. This study aimed to determine whether norepinephrine treatment can enhance the induction of precursor cells from human white adipose tissue to differentiate into adipocytes that express key markers of...

journal_title：Diabetology & metabolic syndrome

authors： Qiu Y,Sun L,Hu X,Zhao X,Shi H,Liu Z,Yin X

更新日期：2020-10-22 00:00:00

abstract：OBJECTIVE:The primary purpose of this study was to examine the construct validity of a continuous metabolic syndrome score (cMetS) in children. The secondary purpose was to identify a cutpoint value(s) for an adverse cMetS based on receiver operating characteristic (ROC) curve analysis. METHODS:378 children aged 7 to ...

journal_title：Diabetology & metabolic syndrome

authors： Eisenmann JC,Laurson KR,DuBose KD,Smith BK,Donnelly JE

更新日期：2010-01-28 00:00:00

abstract：BACKGROUND:Recently, we reported that toll-like receptor (TLR)2 and TLR4 localized on the glomerular endothelium in the glomeruli of streptozotocin (STZ)-induced type 1 diabetic mice and high fat diet feed-induced type 2 diabetic mice, and that periodontal pathogen Porphyromonas gingivalis LPS (Pg-LPS) administration l...

journal_title：Diabetology & metabolic syndrome

authors： Kajiwara K,Takata S,To TT,Takara K,Hatakeyama Y,Tamaoki S,Darveau RP,Ishikawa H,Sawa Y

更新日期：2017-09-22 00:00:00

abstract：Background:Brazil is one of top 10 countries with the highest number of people with diabetes mellitus (DM), affecting 16.8 million peoples. It is estimated that 7.7 million people (20-79 years) in the country have not yet been diagnosed, representing an under-diagnosis rate of 46.0%. Herein we aimed to screen people fo...

journal_title：Diabetology & metabolic syndrome

authors： Correr CJ,Coura-Vital W,Frade JCQP,Nascimento RCRM,Nascimento LG,Pinheiro EB,Ferreira WM,Reis JS,Melo KFS,Pontarolo R,Lenzi MSA,Almeida JV,Pedrosa HC,João WSJ

更新日期：2020-10-08 00:00:00

abstract：BACKGROUND:Angiotensin-converting enzyme (ACE) inhibitors are widely prescribed for patients with diabetes as a nephroprotector drug or to treat hypertension. Generally they are safe for clinical practice, but the relationship between these drugs and angioedema is known. The exact mechanism for ACE inhibitors-induced a...

journal_title：Diabetology & metabolic syndrome

authors： Alencar RC,Cobas RA,Gomes MB

更新日期：2010-01-20 00:00:00

abstract：BACKGROUND:Type 2 diabetes mellitus (DM) globally affects 18-20 % of adults over the age of 65 years. Diabetic kidney disease (DKD) is one of the most frequent and dangerous complications of DM2, affecting about one-third of the patients with DM2. In addition to the pancreas, adipocytes, liver, and intestines, the kidn...

journal_title：Diabetology & metabolic syndrome

authors： Pecoits-Filho R,Abensur H,Betônico CC,Machado AD,Parente EB,Queiroz M,Salles JE,Titan S,Vencio S

更新日期：2016-07-28 00:00:00

abstract：Background:The association of diabetic nephropathy (DN) risk with single nucleotide polymorphisms (SNPs) within Engulfment and Cell Motility 1 (ELMO1) gene and gene-environment synergistic effect have not been extensively examined in, therefore, the purpose of this study is to explore the association between multiple S...

journal_title：Diabetology & metabolic syndrome

authors： Hou Y,Gao Y,Zhang Y,Lin ST,Yu Y,Yang L

更新日期：2019-11-27 00:00:00

abstract：BACKGROUND:An increase in the prevalence of obesity entails great expenditure for governments. Physical exercise is a powerful tool in the combat against obesity and obesity-associated diseases. This study sought to determine the effect of three different exercise protocols on metabolic syndrome and lipid peroxidation ...

journal_title：Diabetology & metabolic syndrome

authors： Botezelli JD,Cambri LT,Ghezzi AC,Dalia RA,M Scariot PP,Ribeiro C,Voltarelli FA,Mello MA

更新日期：2011-12-19 00:00:00

abstract：BACKGROUND:Coronary artery disease (CAD) is a major cardiovascular complication in diabetic patients. Despite the significant association between obesity and diabetes, the majority of the diabetic subjects are not obese in an Asian population. This study evaluated the association between obesity and coronary artery dis...

journal_title：Diabetology & metabolic syndrome

authors： Won KB,Chang HJ,Niinuma H,Sung J,Cho IJ,Shim CY,Hong GR,Kim YJ,Choi BW,Chung N

更新日期：2014-12-05 00:00:00

abstract：BACKGROUND:Vildagliptin, a DPP-4 inhibitor widely used for the treatment of type 2 diabetes mellitus (T2DM), shows beneficial effects on endothelial function. This study aims to evaluate the effect of vildagliptin on endothelial function and arterial stiffness in patients with T2DM and hypertension. METHODS:Fifty over...

journal_title：Diabetology & metabolic syndrome

authors： Cosenso-Martin LN,Giollo-Júnior LT,Martineli DD,Cesarino CB,Nakazone MA,Cipullo JP,Vilela-Martin JF

更新日期：2015-08-26 00:00:00

abstract：:The development of extended-action insulin analogues was motivated by the unfavorable pharmacokinetic (PK) profile of the conventional long-acting insulin formulations, generally associated with marked inter and intra patient variability and site- and dose-dependent effect variation. The new ultra-long insulin analogu...

journal_title：Diabetology & metabolic syndrome

authors： Tambascia MA,Eliaschewitz FG

更新日期：2015-06-26 00:00:00

abstract：: The scope of this short review is to summarise the knowledge gleaned from the fate of drugs transported by albumin upon contact with the target cancer cell or cells in inflamed tissues. The authors expertise covers covalently bound drugs and their cellular uptake and release from albumin. This review therefore aims t...

journal_title：Diabetology & metabolic syndrome

authors： Frei E

更新日期：2011-06-15 00:00:00

abstract：BACKGROUND:We investigated the effect of longitudinal status change in metabolic syndrome (MetS) assessed by two different criteria on new onset of type 2 diabetes (NODM) in a Japanese population. METHODS:The participants were 827 non-diabetic citizens who had undergone medical examinations in 1994 and 2003 or 2004. W...

journal_title：Diabetology & metabolic syndrome

authors： Ohnishi H,Saitoh S,Akasaka H,Furukawa T,Mori M,Miura T

更新日期：2016-09-05 00:00:00

abstract：:Women diagnosed with gestational diabetes mellitus have an increased risk of developing diabetes mellitus, which is a known risk factor for cardiovascular disease and insulin resistance. In the recently published article by Zajdenverg et al., they aimed to identify endothelial dysfunction and cardiovascular risk facto...

journal_title：Diabetology & metabolic syndrome

authors： Kayadibi H,Sertoglu E,Uyanik M

更新日期：2015-03-19 00:00:00

abstract：BACKGROUND:Long QT interval (QT) and abnormal QT dispersion (QTd) are associated with sudden death. The relationship between cardiac autonomic neuropathy (CAN) and QT indices in type 2 diabetic patients were investigated. METHODS:Totally 130 diabetic subjects (mean age 50.87 ± 13.9 years) were included (70 individuals...

journal_title：Diabetology & metabolic syndrome

authors： Vasheghani M,Sarvghadi F,Beyranvand MR,Emami H

更新日期：2020-11-19 00:00:00