当前位置： SCI文献检索 > Diabetology & Metabolic Syndrome期刊下所有文献 > Diabetic nephropathy: recent advances in pathophysiology and challenges in dietary management.

Diabetic nephropathy: recent advances in pathophysiology and challenges in dietary management.

Abstract：

Background:Diabetic nephropathy (DN) or diabetic kidney disease refers to the deterioration of kidney function seen in chronic type 1 and type 2 diabetes mellitus patients. The progression of the disease is known to occur in a series of stages and is linked to glycemic and blood pressure control. However, despite aggressive blood sugar control the prevalence of chronic kidney disease (CKD) in diabetic patients has not witnessed any decrease in the last two decades; which has lead to identification of additional factors in its progression. The nutritional status of patients is an important and modifiable factor that may influence CKD processes and outcome. It directly stems from the traditional dietary choices that patients make due to poor nutritional awareness. Dietary management of DN patients is challenging, as the twin factors of diet overload on kidney function needs to be balanced with malnutrition. Patient education seems to be the key in avoiding overindulgence of carbohydrate and protein-rich foods while favoring inclusion of essential fats in their diet. Conclusion:This review will summarize current advances in staging and molecular pathogenesis of DN. It will highlight recent studies focusing on patient-customized dietary interventions that offer new hope as an effective tool in improving quality of life and delaying disease progression in DN patients.

journal_name

Diabetol Metab Syndr

journal_title

Diabetology & metabolic syndrome

authors

Sulaiman MK

doi

10.1186/s13098-019-0403-4

subject

Has Abstract

pub_date

2019-01-23 00:00:00

pages

7

issn

1758-5996

pii

403

journal_volume

11

pub_type

杂志文章,评审

相关文献

Diabetology & Metabolic Syndrome文献大全

Evaluation of the efficacy and safety of lixisenatide add-on treatment to basal insulin therapy among T2DM patients with different body mass indices from GetGoal trials.
abstract：BACKGROUND:Using patient data from the GetGoal-Duo1, -L, and L-Asia trials, the objectives of this study were to evaluate and compare the impact of lixisenatide once-daily add-on treatment to basal insulin therapy ±oral antidiabetic drugs (OADs) among type 2 diabetes (T2DM) patients subdivided into groups, based on the...

journal_title：Diabetology & metabolic syndrome

pub_type： 杂志文章

doi：10.1186/s13098-015-0104-6

authors： Eto K,Naito Y,Seino Y

更新日期：2015-11-21 00:00:00
Twelve-week randomized study to compare the effect of vildagliptin vs. glibenclamide both added-on to metformin on endothelium function in patients with type 2 diabetes and hypertension.
abstract：BACKGROUND:Vildagliptin, a DPP-4 inhibitor widely used for the treatment of type 2 diabetes mellitus (T2DM), shows beneficial effects on endothelial function. This study aims to evaluate the effect of vildagliptin on endothelial function and arterial stiffness in patients with T2DM and hypertension. METHODS:Fifty over...

journal_title：Diabetology & metabolic syndrome

pub_type： 杂志文章

doi：10.1186/s13098-015-0062-z

authors： Cosenso-Martin LN,Giollo-Júnior LT,Martineli DD,Cesarino CB,Nakazone MA,Cipullo JP,Vilela-Martin JF

更新日期：2015-08-26 00:00:00
Comparison of adipokines in a cross-sectional study with healthy overweight, insulin-sensitive and healthy lean, insulin-resistant subjects, assisted by a family doctor primary care program.
abstract：BACKGROUND:In most individuals, obesity and insulin resistance coexist. However, some individuals have excessive adipose tissue mass but remain insulin sensitive. Moreover, lean individuals can develop acute inflammation-induced insulin resistance, even without excess adipose tissue mass. OBJECTIVE:Our aim was to comp...

journal_title：Diabetology & metabolic syndrome

pub_type： 杂志文章

doi：10.1186/s13098-016-0125-9

authors： Moscavitch SD,Kang HC,Filho RA,Mesquita ET,Neto HC,Rosa ML

更新日期：2016-02-09 00:00:00
Clinical and molecular data from 61 Brazilian cases of Congenital Hyperinsulinemic Hypoglycemia.
abstract：OBJECTIVE:To study the clinical and molecular characteristics of a sample of Brazilian patients with Congenital Hyperinsulinemic Hypoglycemia (CHH). METHODS:Electronic message was sent to members from Endocrinology Department- Brazilian Society of Pediatrics requesting clinical data for all cases of CHH. A whole blood...

journal_title：Diabetology & metabolic syndrome

pub_type： 杂志文章

doi：10.1186/1758-5996-7-5

authors： Del Roio Liberatore R Jr,Ramos PM,Guerra G Jr,Manna TD,Silva IN,Martinelli CE Jr

更新日期：2015-02-18 00:00:00
Adipose tissue-derived cytokines and their correlations with clinical characteristics in Vietnamese patients with type 2 diabetes mellitus.
abstract：Background:Adipokines are involved in the pathogenesis of metabolic disorders including obesity and type 2 diabetes mellitus (T2DM). This study investigates the levels of leptin, resistin, visfatin, secreted frizzled-related protein 5 (SFRP5), monocyte chemoattractant protein-1 (MCP-1) and retinol-binding protein 4 (RB...

journal_title：Diabetology & metabolic syndrome

pub_type： 杂志文章

doi：10.1186/s13098-018-0343-4

authors： Toan NL,Van Hoan N,Cuong DV,Dung NV,Dung PT,Hang NT,Dieu DTH,Chung DT,Son HA,Phong PX,Lenon GB,Van De D,Van Tong H

更新日期：2018-05-15 00:00:00
Association of serum fibroblast growth factor 19 levels with arteriosclerosis parameters assessed by arterial stiffness and atherogenic index of plasma in patients with type 2 diabetes.
abstract：Background:The role of serum fibroblast growth factor 19 (FGF19) in arteriosclerosis is not well known. In the present study, we aimed to explore whether serum FGF19 levels were related to arteriosclerosis parameters, including arterial stiffness and atherogenic index of plasma (AIP), in patients with type 2 diabetes (...

journal_title：Diabetology & metabolic syndrome

pub_type： 杂志文章

doi：10.1186/s13098-020-00552-0

authors： Liu WS,Tang MJ,Xu TL,Su JB,Wang XQ,Xu F,Zhang DM,Zhu Q,Cao J,Wang H

更新日期：2020-05-20 00:00:00
Inadequacies in the habitual nutrient intakes of patients with metabolic syndrome: a cross-sectional study.
abstract：BACKGROUND:Dietary factors are important environmental factors associated with the prevalence of metabolic syndrome (MS). The objective of this study was to assess the habitual nutrient intakes of patients with MS. METHODS:A cross-sectional study included 103 patients (82 % women) with MS seen at the endocrinology out...

journal_title：Diabetology & metabolic syndrome

pub_type： 杂志文章

doi：10.1186/s13098-016-0147-3

authors： da Cunha AT,Pereira HT,de Aquino SL,Sales CH,Sena-Evangelista KC,Lima JG,Lima SC,Pedrosa LF

更新日期：2016-04-14 00:00:00
Alleviating effects of morin against experimentally-induced diabetic osteopenia.
abstract：UNLABELLED: BACKGROUND:Plant flavonoids are emerging as potent therapeutic drugs effective against a wide range of aging diseases particularly bone metabolic disorders. Morin (3,5,7,20,40-pentahydroxyflavone), a member of flavonols, is an important bioactive compound by interacting with nucleic acids, enzymes and prot...

journal_title：Diabetology & metabolic syndrome

pub_type： 杂志文章

doi：10.1186/1758-5996-5-5

authors： Abuohashish HM,Al-Rejaie SS,Al-Hosaini KA,Parmar MY,Ahmed MM

更新日期：2013-02-06 00:00:00
Assessment of dapagliflozin effect on diabetic endothelial dysfunction of brachial artery (ADDENDA-BHS2 trial): rationale, design, and baseline characteristics of a randomized controlled trial.
abstract：Background:Endothelial dysfunction (ED) is a hallmark in type 2 diabetes mellitus (T2DM) that favor both atherogenesis and ischemia and reperfusion injury (IRI). Sodium-glucose-2 co-transporter inhibitors (SGLT2i) may hypothetically improve microvascular and macrovascular functions via a broad spectrum of mechanisms, b...

journal_title：Diabetology & metabolic syndrome

pub_type： 杂志文章

doi：10.1186/s13098-019-0457-3

authors： Cintra RMR,Soares AAS,Breder I,Munhoz DB,Barreto J,Kimura-Medorima ST,Cavalcante P,Zanchetta R,Breder JC,Moreira C,Virginio VW,Bonilha I,Lima-Junior JC,Coelho-Filho OR,Wolf VLW,Guerra-Junior G,Oliveira DC,Haeitmann R,

更新日期：2019-07-31 00:00:00
Analysis of risk factors for carotid intima-media thickness in patients with type 2 diabetes mellitus in Western China assessed by logistic regression combined with a decision tree model.
abstract：Background:Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in patients with type 2 diabetes (T2DM). Carotid intima-media thickness (CIMT) is considered a preclinical stage of atherosclerosis. Therefore, it is necessary to identify the related risk factors for CIMT to facilitate the early pr...

journal_title：Diabetology & metabolic syndrome

pub_type： 杂志文章

doi：10.1186/s13098-020-0517-8

authors： Zhou YY,Qiu HM,Yang Y,Han YY

更新日期：2020-01-28 00:00:00
Post-transplant diabetes mellitus.
abstract：: In recent decades, Diabetes Mellitus has become a severe and growing global public healthcare problem due to the increase of its prevalence, morbidity and mortality. Post-transplant diabetes mellitus (PTDM) is a complication which takes place after a solid organ transplant, and its incidence is widely variable, rangi...

journal_title：Diabetology & metabolic syndrome

pub_type： 杂志文章

doi：10.1186/1758-5996-1-14

authors： Gomes MB,Cobas RA

更新日期：2009-10-05 00:00:00
High frequency of vitamin D receptor gene polymorphism FokI in Brazilian Type 1 diabetes mellitus patients with clinical autoimmune thyroid disease.
abstract：BACKGROUND:Polymorphisms of vitamin D receptor (VDR) gene have been studied as genetic markers of type 1 diabetes mellitus (T1DM) and some studies have reported associations with autoimmune thyroid disease. The aim of this study was to evaluate the relationship between VDR FokI polymorphism (rs10735810), thyroid autoim...

journal_title：Diabetology & metabolic syndrome

pub_type： 杂志文章

doi：10.1186/s13098-016-0145-5

authors： Mory DB,Gabbay MA,Rocco ER,Kasamatsu T,Crispim F,Miranda WL,Dib SA

更新日期：2016-03-22 00:00:00
Low serum galectin-3 concentrations are associated with insulin resistance in patients with type 2 diabetes mellitus.
abstract：BACKGROUND:Galectin-3 is a family of soluble beta-galactoside-binding lectins that play many important regulatory roles in inflammation. Galectin-3-deficient mice have been shown to exhibit excess adiposity, hyperglycemia, insulin resistance and systemic inflammation. We investigated the association between serum galec...

journal_title：Diabetology & metabolic syndrome

pub_type： 杂志文章

doi：10.1186/1758-5996-6-106

authors： Ohkura T,Fujioka Y,Nakanishi R,Shiochi H,Sumi K,Yamamoto N,Matsuzawa K,Izawa S,Ohkura H,Ueta E,Kato M,Miyoshi E,Taniguchi S,Yamamoto K

更新日期：2014-09-27 00:00:00
Comparative efficacy of pharmacological agents on reducing the risk of major adverse cardiovascular events in the hypertriglyceridemia population: a network meta-analysis.
abstract：BACKGROUND:Hypertriglyceridemia (HTG) is considered an independent risk factor for major adverse cardiovascular events (MACE). METHODS:This study analyzed the effects of various agents on MACE risk reduction in HTG (serum triglyceride ≥ 150 mg/dl) populations by performing a network meta-analysis. We performed a frequ...

journal_title：Diabetology & metabolic syndrome

pub_type： 杂志文章

doi：10.1186/s13098-021-00626-7

authors： Qi YY,Yan L,Wang ZM,Wang X,Meng H,Li WB,Chen DC,Li M,Liu J,An ST

更新日期：2021-01-29 00:00:00
Differential role of insulin resistance and β-cell function in the development of prediabetes and diabetes in middle-aged and elderly Chinese population.
abstract：Background:The prevalence of diabetes and prediabetes were estimated to be 10.9% and 35.7% in the Chinese adult population, respectively, and the middle-aged and elderly Chinese are at even higher risk of diabetes and prediabetes than younger population. With the increasing trend of aging in China, the burden of diabet...

journal_title：Diabetology & metabolic syndrome

pub_type： 杂志文章

doi：10.1186/s13098-019-0418-x

authors： Cai X,Xia L,Pan Y,He D,Zhu H,Wei T,He Y

更新日期：2019-03-05 00:00:00
Translation and validation of diabetes self-management profile (DSMP) into Brazilian Portuguese language: first instrument to assess type 1 diabetes self-management in a pediatric population.
abstract：OBJECTIVE:To translate and validate the instrument Diabetes Self-Management Profile (DSMP)-Conventional and Flexible Regimens into Brazilian Portuguese language in order to evaluate the quality of diabetes self-management in children and adolescents with type 1 diabetes and their caregivers. METHODS:DSMP was submitted...

journal_title：Diabetology & metabolic syndrome

pub_type： 杂志文章

doi：10.1186/s13098-017-0250-0

authors： Passone CGB,Esteves LSO,Savoldelli RD,Harris MA,Damiani D,Manna TD

更新日期：2017-07-11 00:00:00
Twice-daily insulin degludec/insulin aspart effectively improved morning and evening glucose levels and quality of life in patients previously treated with premixed insulin: an observational study.
abstract：Background:Previous studies comparing insulin degludec/insulin aspart (IDegAsp) with premixed insulin twice daily among insulin users with type 2 diabetes have not thoroughly investigated differences in the glucose variability and psychological evaluations related to insulin regimen changes. We investigated changes in ...

journal_title：Diabetology & metabolic syndrome

pub_type： 杂志文章

doi：10.1186/s13098-018-0366-x

authors： Fujimoto K,Iwakura T,Aburaya M,Matsuoka N

更新日期：2018-08-16 00:00:00
Interaction between ELMO1 gene polymorphisms and environment factors on susceptibility to diabetic nephropathy in Chinese Han population.
abstract：Background:The association of diabetic nephropathy (DN) risk with single nucleotide polymorphisms (SNPs) within Engulfment and Cell Motility 1 (ELMO1) gene and gene-environment synergistic effect have not been extensively examined in, therefore, the purpose of this study is to explore the association between multiple S...

journal_title：Diabetology & metabolic syndrome

pub_type： 杂志文章

doi：10.1186/s13098-019-0492-0

authors： Hou Y,Gao Y,Zhang Y,Lin ST,Yu Y,Yang L

更新日期：2019-11-27 00:00:00
Results of glycated hemoglobin during treatment with insulin analogues dispensed in the public health system of Federal District in Brazil.
abstract：BACKGROUND:Diabetes treatment requires specialized multi-professional teams, supplies for blood glucose monitoring and training for self-injections of human insulin or insulin analogues. The State Health Secretariat of the Federal District (SHS-FD) has dispensed insulin analogues by means of clinical validated protocol...

journal_title：Diabetology & metabolic syndrome

pub_type： 杂志文章

doi：10.1186/s13098-015-0061-0

authors： Leite EB,Pedrosa HC,Casulari LA

更新日期：2015-08-18 00:00:00
Intensification of insulin therapy in patients with type 2 diabetes: a retrospective, non- interventional cohort study of patients treated with insulin glargine or biphasic human insulin in daily clinical practice.
abstract：BACKGROUND:The aim of this study is to compare the efficacy of intensification of insulin treatment with insulin glargine and biphasic human insulin in patients with type 2 diabetes on concomitant therapy with oral antidiabetic drugs (OAD) in daily clinical practice. METHODS:A retrospective multicentre parallel two-ar...

journal_title：Diabetology & metabolic syndrome

pub_type： 杂志文章

doi：10.1186/1758-5996-5-43

authors： Tentolouris N,Kyriazopoulou V,Makrigiannis D,Baroutsou B

更新日期：2013-08-05 00:00:00
Increased leukotriene B4 plasma concentration in type 2 diabetes individuals with cardiovascular autonomic neuropathy.
abstract：BACKGROUND AND AIM:A low-grade inflammation is associated with cardiac autonomic neuropathy (CAN) and increased concentration of leukotriene B4 (LTB4) was found in individuals with type 1 diabetes and definitive CAN. This cross-sectional study evaluated plasma concentration of LTB4 and of other inflammatory mediators, ...

journal_title：Diabetology & metabolic syndrome

pub_type： 杂志文章

doi：10.1186/s13098-020-00606-3

authors： Neves JAJ,De Matos MR,Ramalho T,Santos-Bezerra DP,Cavalcante CDGD,Alpino Peixoto R,Queiroz MS,Jancar S,Correa-Giannella ML

更新日期：2020-11-12 00:00:00
Prevalence of people at risk of developing type 2 diabetes mellitus and the involvement of community pharmacies in a national screening campaign: a pioneer action in Brazil.
abstract：Background:Brazil is one of top 10 countries with the highest number of people with diabetes mellitus (DM), affecting 16.8 million peoples. It is estimated that 7.7 million people (20-79 years) in the country have not yet been diagnosed, representing an under-diagnosis rate of 46.0%. Herein we aimed to screen people fo...

journal_title：Diabetology & metabolic syndrome

pub_type： 杂志文章

doi：10.1186/s13098-020-00593-5

authors： Correr CJ,Coura-Vital W,Frade JCQP,Nascimento RCRM,Nascimento LG,Pinheiro EB,Ferreira WM,Reis JS,Melo KFS,Pontarolo R,Lenzi MSA,Almeida JV,Pedrosa HC,João WSJ

更新日期：2020-10-08 00:00:00
Using trend arrows in continuous glucose monitoring systems for insulin adjustment in clinical practice: Brazilian Diabetes Society Position Statement.
abstract：:This manuscript reports the Brazilian Diabetes Society Position Statement for insulin adjustments based on trend arrows observed in continuous glucose monitoring systems. The Brazilian Diabetes Society supports the utilization of trend arrows for insulin dose adjustments in patients with diabetes on basal-bolus insuli...

journal_title：Diabetology & metabolic syndrome

pub_type： 信件

doi：10.1186/s13098-020-00607-2

authors： Rodacki M,Calliari LE,Ramalho AC,Vianna AGD,Franco DR,Melo KFS,Araujo LR,Krakauer M,Scharf M,Minicucci W,Ziegler R,Gabbay M

更新日期：2021-01-03 00:00:00
Link between insulin resistance and hypertension: What is the evidence from evolutionary biology?
abstract：:Insulin resistance and hypertension are considered as prototypical "diseases of civilization" that are manifested in the modern environment as plentiful food and sedentary life. The human propensity for insulin resistance and hypertension is a product, at least in part, of our evolutionary history. Adaptation to ancie...

journal_title：Diabetology & metabolic syndrome

pub_type： 杂志文章

doi：10.1186/1758-5996-6-12

authors： Zhou MS,Wang A,Yu H

更新日期：2014-01-31 00:00:00
Comparison between binocular indirect ophthalmoscopy and digital retinography for diabetic retinopathy screening: the multicenter Brazilian Type 1 Diabetes Study.
abstract：BACKGROUND:Diabetic retinopathy is the main cause of preventable blindness in the economically active population in western countries. Diabetic retinopathy screening is effective in preventing blindness and can be performed through various diagnostic methods. Our objective is to compare binocular indirect ophthalmoscop...

journal_title：Diabetology & metabolic syndrome

pub_type： 杂志文章

doi：10.1186/s13098-015-0110-8

authors： Malerbi FK,Morales PH,Farah ME,Drummond KR,Mattos TC,Pinheiro AA,Mallmann F,Perez RV,Leal FS,Gomes MB,Dib SA,Brazilian Type 1 Diabetes Study Group.

更新日期：2015-12-21 00:00:00
The multiple functions of the endocannabinoid system: a focus on the regulation of food intake.
abstract：BACKGROUND:Cannabis sativa (also known as marijuana) has been cultivated by man for more than 5,000 years. However, there was a rise in its use in the 20th century for recreational, religious or spiritual, and medicinal purposes. The main psychoactive constituent of cannabis, whose structure was identified in the 1960'...

journal_title：Diabetology & metabolic syndrome

pub_type： 杂志文章

doi：10.1186/1758-5996-2-5

authors： Tibiriça E

更新日期：2010-01-21 00:00:00
Microencapsulation of cellular aggregates composed of differentiated insulin and glucagon-producing cells from human mesenchymal stem cells derived from adipose tissue.
abstract：Background:In type I diabetes mellitus (T1DM) pancreatic β cells are destroyed. Treatment entails exogenous insulin administration and strict diet control, yet optimal glycemic control is hardly attainable. Islet transplant could be an alternative in patients with poor glycemic control, but inefficient islet purificati...

journal_title：Diabetology & metabolic syndrome

pub_type： 杂志文章

doi：10.1186/s13098-020-00573-9

authors： Jara C,Oyarzun-Ampuero F,Carrión F,González-Echeverría E,Cappelli C,Caviedes P

更新日期：2020-08-05 00:00:00
Construct validity of a continuous metabolic syndrome score in children.
abstract：OBJECTIVE:The primary purpose of this study was to examine the construct validity of a continuous metabolic syndrome score (cMetS) in children. The secondary purpose was to identify a cutpoint value(s) for an adverse cMetS based on receiver operating characteristic (ROC) curve analysis. METHODS:378 children aged 7 to ...

journal_title：Diabetology & metabolic syndrome

pub_type： 杂志文章

doi：10.1186/1758-5996-2-8

authors： Eisenmann JC,Laurson KR,DuBose KD,Smith BK,Donnelly JE

更新日期：2010-01-28 00:00:00
Different exercise protocols improve metabolic syndrome markers, tissue triglycerides content and antioxidant status in rats.
abstract：BACKGROUND:An increase in the prevalence of obesity entails great expenditure for governments. Physical exercise is a powerful tool in the combat against obesity and obesity-associated diseases. This study sought to determine the effect of three different exercise protocols on metabolic syndrome and lipid peroxidation ...

journal_title：Diabetology & metabolic syndrome

pub_type： 杂志文章

doi：10.1186/1758-5996-3-35

authors： Botezelli JD,Cambri LT,Ghezzi AC,Dalia RA,M Scariot PP,Ribeiro C,Voltarelli FA,Mello MA

更新日期：2011-12-19 00:00:00
Aliskiren effect on non-alcoholic steatohepatitis in metabolic syndrome.
abstract：BACKGROUND:Non-alcoholic steatohepatitis (NASH) is highly associated with metabolic syndrome, a major cause of morbidity in the globalized society. The renin-angiotensin system (RAS) influences hepatic fatty acid metabolism, inflammation and fibrosis. Thus, in the present study, we aimed to evaluate the effect of alisk...

journal_title：Diabetology & metabolic syndrome

pub_type： 杂志文章

doi：10.1186/s13098-017-0282-5

authors： Ramalho FN,Sanches SC,Foss MC,Augusto MJ,Silva DM,Oliveira AM,Ramalho LN

更新日期：2017-10-13 00:00:00