Moderate- to high-intensity statins for secondary prevention in patients with type 2 diabetes mellitus on dialysis after acute myocardial infarction.

abstract：BACKGROUND:The aim of this study is to compare the efficacy of intensification of insulin treatment with insulin glargine and biphasic human insulin in patients with type 2 diabetes on concomitant therapy with oral antidiabetic drugs (OAD) in daily clinical practice. METHODS:A retrospective multicentre parallel two-ar...

journal_title：Diabetology & metabolic syndrome

authors： Tentolouris N,Kyriazopoulou V,Makrigiannis D,Baroutsou B

更新日期：2013-08-05 00:00:00

abstract：BACKGROUND:In mammals, the temperature rhythm is regulated by the circadian pacemaker located in the suprachiasmatic nuclei, and is considered a "marker rhythm". Melatonin, the pineal gland hormone, is a major regulator of the endogenous rhythms including body temperature. Its production is influenced by many factors, ...

journal_title：Diabetology & metabolic syndrome

authors： Ramos-Lobo AM,Buonfiglio DC,Cipolla-Neto J

更新日期：2015-04-29 00:00:00

abstract：BACKGROUND:The objective was to evaluate the muscle glucose metabolism in rats fed a fructose-rich diet after fetal protein malnutrition, at rest and after acute physical exercise at maximal lactate steady-state intensity. METHODS:The male offspring born of mothers fed on a balanced or low-protein diet were split in f...

journal_title：Diabetology & metabolic syndrome

authors： Cambri LT,Ribeiro C,Botezelli JD,Ghezzi AC,Mello MA

更新日期：2014-11-06 00:00:00

abstract：BACKGROUND:Dipeptidyl peptidase-4 (DDP4) is an enzyme responsible for glucagon-like peptide-1 inactivation and plays an important role in glucose metabolism. OBJECTIVE:The aim of this study was to evaluate DPP4 levels in patients with familial partial lipodystrophy type 2 (FPLD2) and correlate it with body fat distrib...

journal_title：Diabetology & metabolic syndrome

authors： Valerio CM,de Almeida JS,Moreira RO,Aguiar LBS,Siciliano PO,Carvalho DP,Godoy-Matos AF

更新日期：2017-04-24 00:00:00

abstract：BACKGROUND:The single-center, open-label, four-arm, exploratory study investigates the relation of different anti-diabetics to serum levels of active TGF-β, a known pro-fibrotic stimulus, before and after a defined test meal. FINDINGS:We investigated sera of patients with type 2 diabetes mellitus (T2DM) treated with m...

journal_title：Diabetology & metabolic syndrome

authors： Pscherer S,Freude T,Forst T,Nussler AK,Braun KF,Ehnert S

更新日期：2013-08-31 00:00:00

abstract：BACKGROUND:Cannabis sativa (also known as marijuana) has been cultivated by man for more than 5,000 years. However, there was a rise in its use in the 20th century for recreational, religious or spiritual, and medicinal purposes. The main psychoactive constituent of cannabis, whose structure was identified in the 1960'...

journal_title：Diabetology & metabolic syndrome

authors： Tibiriça E

更新日期：2010-01-21 00:00:00

abstract：BACKGROUND:An increase in the prevalence of obesity entails great expenditure for governments. Physical exercise is a powerful tool in the combat against obesity and obesity-associated diseases. This study sought to determine the effect of three different exercise protocols on metabolic syndrome and lipid peroxidation ...

journal_title：Diabetology & metabolic syndrome

authors： Botezelli JD,Cambri LT,Ghezzi AC,Dalia RA,M Scariot PP,Ribeiro C,Voltarelli FA,Mello MA

更新日期：2011-12-19 00:00:00

abstract：BACKGROUND:In most individuals, obesity and insulin resistance coexist. However, some individuals have excessive adipose tissue mass but remain insulin sensitive. Moreover, lean individuals can develop acute inflammation-induced insulin resistance, even without excess adipose tissue mass. OBJECTIVE:Our aim was to comp...

journal_title：Diabetology & metabolic syndrome

authors： Moscavitch SD,Kang HC,Filho RA,Mesquita ET,Neto HC,Rosa ML

更新日期：2016-02-09 00:00:00

abstract：BACKGROUND:Vildagliptin, a DPP-4 inhibitor widely used for the treatment of type 2 diabetes mellitus (T2DM), shows beneficial effects on endothelial function. This study aims to evaluate the effect of vildagliptin on endothelial function and arterial stiffness in patients with T2DM and hypertension. METHODS:Fifty over...

journal_title：Diabetology & metabolic syndrome

authors： Cosenso-Martin LN,Giollo-Júnior LT,Martineli DD,Cesarino CB,Nakazone MA,Cipullo JP,Vilela-Martin JF

更新日期：2015-08-26 00:00:00

abstract：Objective:Several controversial findings have been reported on treatment outcomes for diabetic stroke patients that received thrombolysis therapy in the hospital. We determined whether the association between telestroke technology, thrombolysis therapy and clinical risk factors in diabetic acute ischemic stroke may res...

journal_title：Diabetology & metabolic syndrome

authors： Nathaniel TI,Ubah C,Wormack L,Gainey J

更新日期：2019-05-09 00:00:00

abstract：: Metabolic Syndrome (MS) increases the risk for Coronary Artery Disease, stroke and diabetes. MS is twice more common amongst South Asian immigrants in US compared to native Caucasians. There are no nationally representative studies on prevalence of MS from any of the South Asian countries. The present study aims to e...

journal_title：Diabetology & metabolic syndrome

authors： Katulanda P,Ranasinghe P,Jayawardana R,Sheriff R,Matthews DR

更新日期：2012-05-31 00:00:00

abstract：BACKGROUND:The oral DPP-4 inhibitors are new incretin-based therapies for treatment of type 2 diabetes. To assess the efficacy and safety of three DPP-4 inhibitors (Saxagliptin, Sitagliptin and Vildagliptin) as add-on therapy to dual combination of traditional oral hypoglycemic agents in Chinese type 2 diabetes patient...

journal_title：Diabetology & metabolic syndrome

authors： Li CJ,Liu XJ,Bai L,Yu Q,Zhang QM,Yu P,Yu DM

更新日期：2014-05-31 00:00:00

abstract：BACKGROUND:Recently, we reported that toll-like receptor (TLR)2 and TLR4 localized on the glomerular endothelium in the glomeruli of streptozotocin (STZ)-induced type 1 diabetic mice and high fat diet feed-induced type 2 diabetic mice, and that periodontal pathogen Porphyromonas gingivalis LPS (Pg-LPS) administration l...

journal_title：Diabetology & metabolic syndrome

authors： Kajiwara K,Takata S,To TT,Takara K,Hatakeyama Y,Tamaoki S,Darveau RP,Ishikawa H,Sawa Y

更新日期：2017-09-22 00:00:00

abstract：Background:Whether polymorphisms in tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), interleukin-10 (IL-10) or adiponectin (ADIPOQ) influence the risk of gestational diabetes mellitus (GDM) or not remain inconclusive. Therefore, the authors conducted a meta-analysis to robustly assess relationships between polymo...

journal_title：Diabetology & metabolic syndrome

authors： Huang Q,Wang Y,Gu B,Xu Y

更新日期：2020-09-17 00:00:00

abstract：OBJECTIVE:The primary purpose of this study was to examine the construct validity of a continuous metabolic syndrome score (cMetS) in children. The secondary purpose was to identify a cutpoint value(s) for an adverse cMetS based on receiver operating characteristic (ROC) curve analysis. METHODS:378 children aged 7 to ...

journal_title：Diabetology & metabolic syndrome

authors： Eisenmann JC,Laurson KR,DuBose KD,Smith BK,Donnelly JE

更新日期：2010-01-28 00:00:00

abstract：Background:To investigate the association of low carbohydrate diet (LCD) score with the risk of type 2 diabetes among adults. Methods:This cohort study was conducted on 4356 healthy participants aged ≥ 19 years old, who were followed-up for a mean duration of 3 years within the framework of the Tehran Lipid and Glucos...

journal_title：Diabetology & metabolic syndrome

authors： Sali S,Farhadnejad H,Asghari G,Teymoori F,Mirmiran P,Djazayeri A,Azizi F

更新日期：2020-10-07 00:00:00

abstract：BACKGROUND:Polymorphisms in genes encoding adiponectin (ADIPOQ) and interleukin-6 (IL6) have been associated with adiposity and obese-related phenotypes. This study investigated the relationship of ADIPOQ and IL6 gene polymorphisms with pro-inflammatory and cardiometabolic markers in obese patients. METHODS:Anthropome...

journal_title：Diabetology & metabolic syndrome

authors： de Oliveira R,Moraes TI,Cerda A,Hirata MH,Fajardo CM,Sousa MC,Dorea EL,Bernik MM,Hirata RD

更新日期：2015-04-11 00:00:00

abstract：Background:Genome-wide association studies have shown that risk alleles on chromosome 9p21.3 locus, are associated with increasing the risk of cardiovascular diseases (CVDs). Several epidemiological studies have found that metabolic syndrome (MetS) is associated with CVDs. Dietary antioxidants also have shown to have p...

journal_title：Diabetology & metabolic syndrome

authors： Mirzababaei A,Mollahosseini M,Rahimi MH,Yekaninejad MS,Maghbooli Z,Sobhani R,Mirzaei K

更新日期：2018-10-18 00:00:00

abstract：Background:Adipokines are involved in the pathogenesis of metabolic disorders including obesity and type 2 diabetes mellitus (T2DM). This study investigates the levels of leptin, resistin, visfatin, secreted frizzled-related protein 5 (SFRP5), monocyte chemoattractant protein-1 (MCP-1) and retinol-binding protein 4 (RB...

journal_title：Diabetology & metabolic syndrome

authors： Toan NL,Van Hoan N,Cuong DV,Dung NV,Dung PT,Hang NT,Dieu DTH,Chung DT,Son HA,Phong PX,Lenon GB,Van De D,Van Tong H

更新日期：2018-05-15 00:00:00

abstract：Background:Metabolic syndrome is characterized by macrophage infiltration and inflammatory responses-metaflammation in adipose tissue. IL-6 and IL-1β could mediate the inflammatory responses in macrophage stimulated-preadipocytes by modulating MAPK and NF-κB pathways. To test this hypothesis we used antibodies to block...

journal_title：Diabetology & metabolic syndrome

authors： Zhu J,Bing C,Wilding JPH

更新日期：2019-01-25 00:00:00

abstract：:Insulin resistance and hypertension are considered as prototypical "diseases of civilization" that are manifested in the modern environment as plentiful food and sedentary life. The human propensity for insulin resistance and hypertension is a product, at least in part, of our evolutionary history. Adaptation to ancie...

journal_title：Diabetology & metabolic syndrome

authors： Zhou MS,Wang A,Yu H

更新日期：2014-01-31 00:00:00

abstract：BACKGROUND:Many patients with chronic heart failure (CHF) are believed to have unrecognized diabetes, which is associated with a worse prognosis. This study aimed to describe glucose tolerance in a general stable CHF population and to identify determinants of glucose tolerance focusing on body composition and skeletal ...

journal_title：Diabetology & metabolic syndrome

authors： Stevens AL,Hansen D,Vandoren V,Westerlaken R,Creemers A,Eijnde BO,Dendale P

更新日期：2014-03-27 00:00:00

abstract：BACKGROUND:Non-alcoholic steatohepatitis (NASH) is highly associated with metabolic syndrome, a major cause of morbidity in the globalized society. The renin-angiotensin system (RAS) influences hepatic fatty acid metabolism, inflammation and fibrosis. Thus, in the present study, we aimed to evaluate the effect of alisk...

journal_title：Diabetology & metabolic syndrome

authors： Ramalho FN,Sanches SC,Foss MC,Augusto MJ,Silva DM,Oliveira AM,Ramalho LN

更新日期：2017-10-13 00:00:00

abstract：Background:Exercise can disrupt homeostasis and trigger many adaptive responses in different hormonal axes. The study of hormonal interactions with physical activity is highly complex due to the number of variables, such as exercise duration, exercise intensity, individual level of training, circadian rhythm, nutrition...

journal_title：Diabetology & metabolic syndrome

authors： de Souza HS,Jardim TV,Barroso WKS,de Oliveira Vitorino PV,Souza ALL,Jardim PCV

更新日期：2019-02-15 00:00:00

abstract：Background:The prevalence of diabetes and prediabetes were estimated to be 10.9% and 35.7% in the Chinese adult population, respectively, and the middle-aged and elderly Chinese are at even higher risk of diabetes and prediabetes than younger population. With the increasing trend of aging in China, the burden of diabet...

journal_title：Diabetology & metabolic syndrome

authors： Cai X,Xia L,Pan Y,He D,Zhu H,Wei T,He Y

更新日期：2019-03-05 00:00:00

abstract：UNLABELLED: BACKGROUND:Plant flavonoids are emerging as potent therapeutic drugs effective against a wide range of aging diseases particularly bone metabolic disorders. Morin (3,5,7,20,40-pentahydroxyflavone), a member of flavonols, is an important bioactive compound by interacting with nucleic acids, enzymes and prot...

journal_title：Diabetology & metabolic syndrome

authors： Abuohashish HM,Al-Rejaie SS,Al-Hosaini KA,Parmar MY,Ahmed MM

更新日期：2013-02-06 00:00:00

abstract：Background:Previous studies comparing insulin degludec/insulin aspart (IDegAsp) with premixed insulin twice daily among insulin users with type 2 diabetes have not thoroughly investigated differences in the glucose variability and psychological evaluations related to insulin regimen changes. We investigated changes in ...

journal_title：Diabetology & metabolic syndrome

authors： Fujimoto K,Iwakura T,Aburaya M,Matsuoka N

更新日期：2018-08-16 00:00:00

abstract：BACKGROUND:Asymmetric dimethylarginine (ADMA) is an endogenous competitive inhibitor of nitric oxide (NO) synthetase. Elevated ADMA reduces NO formation and is associated with endothelial dysfunction. The aims of this study were to evaluate endothelial function and the cardiovascular risk (CVR) profile in patients with...

journal_title：Diabetology & metabolic syndrome

authors： Sayki Arslan M,Turhan S,Dincer I,Mizrak D,Corapcioglu D,Idilman R

更新日期：2014-10-14 00:00:00

abstract：BACKGROUND:Type 1 diabetes mellitus in pregnant women is associated with an increased risk of congenital malformations, obstetric complications, neonatal morbidity, and mortality. Our aim was to evaluate which factors from the first trimester of pregnancy have a significant impact on the pregnancy outcomes of women wit...

journal_title：Diabetology & metabolic syndrome

authors： Timar B,Timar R,Albai A,Stoian D,Nitu R,Craina M

更新日期：2014-11-22 00:00:00

abstract：Background:The present study identified whether glycemic variability (GV) was associated with vascular calcification and explored the underlying mechanisms. Methods:Eighty-four consecutive type 2 diabetic patients with unstable angina (UA) were included from January 2018 to June 2018 to calculate calcification scores ...

journal_title：Diabetology & metabolic syndrome

authors： Zhang L,Sun H,Liu S,Gao J,Xia J

更新日期：2019-08-19 00:00:00