Evolution in functionality of a metastatic pancreatic neuroendocrine tumour (pNET) causing Cushing's syndrome: treatment response with chemotherapy.

abstract：BACKGROUND:Our aim was to assess the associations between vitamin D (vitD) status, metabolic profile and polymorphisms in genes involved in the transport (Group-Component: GC) and the hydroxylation (NAD synthetase 1: NADSYN1) of 25 hydroxyvitamin D (25(OH)D) in non-diabetic individuals. METHODS:We conducted a cross-se...

journal_title：BMC endocrine disorders

authors： Foucan L,Vélayoudom-Céphise FL,Larifla L,Armand C,Deloumeaux J,Fagour C,Plumasseau J,Portlis ML,Liu L,Bonnet F,Ducros J

更新日期：2013-09-29 00:00:00

abstract：BACKGROUND:The prevalence of type 2 diabetes mellitus (T2DM) is expected to increase from 7.7% in 2017 to 8.4% in 2045 worldwide. Diabetes complications contribute to morbidity and mortality. To evaluate whether the diabetes complications severity index (DCSI) was associated with increased risks of mortality and hospit...

journal_title：BMC endocrine disorders

authors： Yoo H,Choo E,Lee S

更新日期：2020-08-10 00:00:00

abstract：BACKGROUND:Ovarian reserve, vital for reproductive function, can be adversely affected by thyroid diseases. Despite alternations of thyroid hormones with ageing, data on interactions between the overtime trend of thyroid functions and ovarian reserve status has rarely been reported. We aimed to examine the overtime tre...

journal_title：BMC endocrine disorders

authors： Bahri S,Tehrani FR,Amouzgar A,Rahmati M,Tohidi M,Vasheghani M,Azizi F

更新日期：2019-05-07 00:00:00

abstract：BACGROUND:To assess the contribution of macroprolactin to high serum prolactin levels and their association with thyroid status and thyroid autoimmunity during pregnancy. METHODS:138 pregnant women who suspected of having thyroid dysfunction were studied and divided into three groups according to the thyroid status; g...

journal_title：BMC endocrine disorders

authors： Guclu M,Cander S,Kiyici S,Vatansever E,Hacihasanoğlu AB,Kisakol G

更新日期：2015-06-20 00:00:00

abstract：BACKGROUND:Sirtuin 1 (SIRT1) and sirtuin 3 (SIRT3) proteins have an important role in counteracting oxidative stress. Although diabetes and hypothyroidism (HT) are both characterized by oxidative stress, the mechanisms are not fully understood. This study investigated the effects of type 1 diabetes (T1D), type 2 diabet...

journal_title：BMC endocrine disorders

authors： Al-Khaldi A,Sultan S

更新日期：2019-02-08 00:00:00

abstract：BACKGROUND:Ectopic adrenocorticotropic hormone (ACTH) syndrome (EAS) is caused by tumours releasing ACTH. Ectopic ACTH-producing tumour regression is rarely induced using steroidogenesis inhibitors. We presented a case of EAS in which ACTH production by a lung tumour was reduced by metyrapone (MTP) and also reviewed pr...

journal_title：BMC endocrine disorders

authors： Iwayama H,Hirase S,Nomura Y,Ito T,Morita H,Otake K,Okumura A,Takagi J

更新日期：2018-03-27 00:00:00

abstract：BACKGROUND:Feel4Diabetes was a school and community based intervention aiming to promote healthy lifestyle and tackle obesity for the prevention of type 2 diabetes among families in 6 European countries. We conducted this literature review in order to guide the development of evidence-based implementation of the Feel4D...

journal_title：BMC endocrine disorders

authors： Kivelä J,Wikström K,Virtanen E,Georgoulis M,Cardon G,Civeira F,Iotova V,Karuranga E,Ko W,Liatis S,Makrilakis K,Manios Y,Mateo-Gallego R,Nanasi A,Rurik I,Tankova T,Tsochev K,Van Stappen V,Lindström J,Feel4Diabetes re

更新日期：2020-03-12 00:00:00

abstract：BACKGROUND:Insulin autoimmune syndrome (IAS) is a rare cause of hypoglycemia and is characterized by the presence of insulin autoantibodies. Patients with IAS usually complain of hypoglycemia without any previous insulin received. Glucocorticoids and immunosuppressants are used to treat IAS. CASE PRESENTATION:We repor...

journal_title：BMC endocrine disorders

authors： Shen Y,Song X,Ren Y

更新日期：2019-12-28 00:00:00

abstract：BACKGROUND:Diabetic foot ulceration is receiving more attention because of its high amputation and mortality rate. It is essential to establish the frequency of amputations in people with diabetes after any change to the management of diabetic foot care. The present study aim to compare the frequency of lower-extremity...

journal_title：BMC endocrine disorders

authors： Wang C,Mai L,Yang C,Liu D,Sun K,Song W,Luo B,Li Y,Xu M,Zhang S,Li F,Ren M,Yan L

更新日期：2016-07-07 00:00:00

abstract：BACKGROUND:The objective was to examine how the indigenous naming, indigenous self-diagnosis and management of diabetes evolved with awareness in order to develop a socially oriented theoretical model for its care. METHODS:The data was collected through a one-year extended participant observation in Bafut, a rural hea...

journal_title：BMC endocrine disorders

authors： Awah PK,Unwin NC,Phillimore PR

更新日期：2009-02-19 00:00:00

abstract：BACKGROUND:Diabetes mellitus (DM) leads to multiple complications, including severe hypoglycaemia events (SHEs). SHEs can impact a patient's quality of life and compliance and may directly result in additional costs to the health care system. The aim of this review was to evaluate the risk of severe hypoglycaemia in pa...

journal_title：BMC endocrine disorders

authors： Czech M,Rdzanek E,Pawęska J,Adamowicz-Sidor O,Niewada M,Jakubczyk M

更新日期：2015-10-12 00:00:00

abstract：BACKGROUND:The purpose of this study was to evaluate the association between blood manganese levels and the prevalence of chronic diseases in the Korean population. METHODS:This was a cross-sectional study based on the Korean National Health and Nutrition Examination Survey (KNAHNES). The study included 3996 participa...

journal_title：BMC endocrine disorders

authors： Koh ES,Kim SJ,Yoon HE,Chung JH,Chung S,Park CW,Chang YS,Shin SJ

更新日期：2014-03-08 00:00:00

abstract：BACKGROUND:Subclinical hypothyroidism (SH) is associated with adverse obstetric outcomes and neurodevelopment disorders. Both iodine deficiency and excess are associated with SH; however, few data regarding iodine nutrition status of pregnant women with SH are available. This study aimed to clarify whether iodine defic...

journal_title：BMC endocrine disorders

authors： Wang K,Zhang J,Li F,Zhang W,Wang H,Ding L,Liu Y,Lin L,Zhang S,Zhu M

更新日期：2017-02-17 00:00:00

abstract：BACKGROUND:Irisin is a myokine that leads to increased energy expenditure by stimulating the browning of white adipose tissue. We aimed to investigate the association of serum irisin levels with metabolic parameters in middle aged Chinese population. METHODS:The study was based on a cross-sectional analysis of data fr...

journal_title：BMC endocrine disorders

authors： Tang L,Tong Y,Zhang F,Chen G,Zhang YC,Jobin J,Tong N

更新日期：2019-12-27 00:00:00

abstract：BACKGROUND:Islet cell transplantation is a method to stabilize type 1 diabetes patients with hypoglycemia unawareness and unstable blood glucose levels by reducing insulin dependency and protecting against severe hypoglycemia through restoring endogenous insulin secretion. This study analyses the current cost-effective...

journal_title：BMC endocrine disorders

authors： Wallner K,Shapiro AM,Senior PA,McCabe C

更新日期：2016-04-09 00:00:00

abstract：BACKGROUND:Type 2 diabetic patients display significantly higher incidence of cardiovascular (CV) events including stroke compared to non-diabetics. Morning blood pressure surge (MBPS) and blunted systolic night-day (SND) ratio have been associated with CV events in hypertensive patients. No studies have evaluated MBPS...

journal_title：BMC endocrine disorders

authors： Lyhne JM,Laugesen E,Høyem P,Cichosz S,Christiansen JS,Knudsen ST,Hansen KW,Hansen TK,Poulsen PL

更新日期：2015-12-03 00:00:00

abstract：BACKGROUND:Insulin and insulin-like growth factor (IGF)-1 coupled with growth hormone helps control timing of sexual maturation. Mutations and variants in multiple genes are associated with development or reduced risk of central precocious puberty (CPP). METHODS:We assessed single nucleotide polymorphisms (SNPs) in th...

journal_title：BMC endocrine disorders

authors： Chang HP,Yang SF,Wang SL,Su PH

更新日期：2018-09-19 00:00:00

abstract：BACKGROUND:The aim of this study is to perform a cost-effectiveness comparison between palpation-guided thyroid fine-needle aspiration biopsies (P-FNA) and ultrasound-guided thyroid FNA biopsies (USG-FNA). METHODS:Each nodule was considered as a case. Diagnostic steps were history and physical examination, TSH measure...

journal_title：BMC endocrine disorders

authors： Can AS

更新日期：2009-05-16 00:00:00

abstract：BACKGROUND:Type 2 diabetes mellitus (T2DM) and several types of neurodegeneration, including Alzheimer's, are linked to insulin-resistance, and chronic high dietary fat intake causes T2DM with mild neurodegeneration. Intra-cerebral Streptozotocin, a nitrosamine-related compound, causes neurodegeneration, whereas periph...

journal_title：BMC endocrine disorders

authors： Tong M,Longato L,de la Monte SM

更新日期：2010-03-19 00:00:00

abstract：BACKGROUND:There have only been a few reports about use of dipeptidyl peptidase 4 (DPP-4) inhibitors in elderly patients with type 2 diabetes mellitus (T2DM), suggesting that the safety of these agents has not been sufficiently demonstrated. We performed a comparative review of the efficacy and safety of sitagliptin fo...

journal_title：BMC endocrine disorders

authors： Umezawa S,Kubota A,Maeda H,Kanamori A,Matoba K,Jin Y,Minagawa F,Obana M,Iemitsu K,Ito S,Amamiya H,Kaneshiro M,Takai M,Kaneshige H,Hoshino K,Ishikawa M,Minami N,Takuma T,Sasai N,Aoyagi S,Kawata T,Mokubo A,Miyai

更新日期：2015-07-03 00:00:00

abstract：BACKGROUND:This study tested the association between serum levels of microRNA-486, -146b and -15b and betatrophin in normal and obese children with/without type 2 diabetes mellitus (T2DM). METHODS:the study included 120 children; divided into three groups: G1 (50 healthy), G2 (35 obese) and G3 (35 obese with T2DM). Th...

journal_title：BMC endocrine disorders

authors： Mohany KM,Al Rugaie O,Al-Wutayd O,Al-Nafeesah A,Saleem TH

更新日期：2020-09-29 00:00:00

abstract：BACKGROUND:Radioisotope scanning is important to diagnose subacute thyroiditis (SAT), but it's not always available. So we aim to establish a diagnostic scale for SAT without radioisotope scanning. METHODS:The suspected SAT patients hospitalized in Yuebei people's Hospital from January 2012 to December 2016 were selec...

journal_title：BMC endocrine disorders

authors： Xiong Z,Luo C,Wang L,Xiong B,Wu J

更新日期：2020-05-27 00:00:00

abstract：BACKGROUND:Non-thyroidal illness syndrome (NTIS) is a characteristic functional constellation of thyrotropic feedback control that frequently occurs in critically ill patients. Although this condition is associated with significantly increased morbidity and mortality, there is still controversy on whether NTIS is cause...

journal_title：BMC endocrine disorders

authors： Dietrich JW,Stachon A,Antic B,Klein HH,Hering S

更新日期：2008-10-13 00:00:00

abstract：BACKGROUND:The hormone somatostatin inhibits growth hormone release from the pituitary gland and is theoretically linked to diabetes and diabetes related complications. This study aimed to investigate the relationship between levels of the stable somatostatin precursor, N-terminal prosomatostatin (NT-proSST), with mort...

journal_title：BMC endocrine disorders

authors： van Dijk PR,Landman GW,van Essen L,Struck J,Groenier KH,Bilo HJ,Bakker SJ,Kleefstra N

更新日期：2015-04-14 00:00:00

abstract：BACKGROUND:Anti-Müllerian hormone (AMH) is now considered the best serum biomarker of ovarian reserve, while basal sex hormones are classic markers used for assessing ovarian reserve. The interaction between AMH and sex hormones are complicated and not sufficiently addressed. In this study, we took diminished ovarian r...

journal_title：BMC endocrine disorders

authors： Lv PP,Jin M,Rao JP,Chen J,Wang LQ,Huang CC,Yang SQ,Yao QP,Feng L,Shen JM,Feng C

更新日期：2020-07-08 00:00:00

abstract：BACKGROUND:Vitamin D deficiency is pandemic while resources available to measure 25-hydroxyvitamin D (25OHD) are limited. The present study aimed to verify whether sun exposure measured by a structured questionnaire could predict serum 25OHD concentrations in healthy Caucasian individuals living in a tropical area. ME...

journal_title：BMC endocrine disorders

authors： Bittar FB,Castro CHM,Szejnfeld VL

更新日期：2018-07-03 00:00:00

abstract：BACKGROUND:To estimate the proportion of diabetic patients (DPts) with peripheral vascular disease treated at a primary health care site after an endocrinologist-based intervention, who meet ATP III and Steno targets of metabolic control, as well as to compare the outcome with the results of the patients treated by end...

journal_title：BMC endocrine disorders

authors： Duran A,Runkle I,Matía P,de Miguel MP,Garrido S,Cervera E,Fernandez MD,Torres P,Lillo T,Martin P,Cabrerizo L,de la Torre NG,Calle JR,Ibarra J,Charro AL,Calle-Pascual AL

更新日期：2008-07-31 00:00:00

abstract：BACKGROUND:Addison's disease, or primary adrenal insufficiency, is often associated with reduced well-being and fatigue despite use of currently recommended adrenal hormone replacement. Hypoglycaemia is a known manifestation of glucocorticoid deficiency, but is generally considered rare in adults and not relevant to tr...

journal_title：BMC endocrine disorders

authors： Petersen KS,Rushworth RL,Clifton PM,Torpy DJ

更新日期：2015-10-24 00:00:00

abstract：UNLABELLED: BACKGROUND:Severe hypoglycaemia (SH) is one of the most feared complications of type 1 diabetes (T1DM) with a reported prevalence of nearly 40%. In randomized trials of Multiple Daily Injections (MDI) and Continuous Subcutaneous Insulin Infusion (CSII) therapy there is a possible benefit of CSII in reducin...

journal_title：BMC endocrine disorders

authors： Little S,Chadwick T,Choudhary P,Brennand C,Stickland J,Barendse S,Olateju T,Leelarathna L,Walkinshaw E,Tan HK,Marshall SM,Thomas RM,Heller S,Evans M,Kerr D,Flanagan D,Speight J,Shaw JA

更新日期：2012-12-13 00:00:00

abstract：BACKGROUND:This study aimed to measure the effect of diabetes education using the novel method of "diabetes conversation map (DCM)" as compared to routine counselling (RC) on diabetes management self-efficacy (DMSE) among patients living with type 2 diabetes in Karachi, Pakistan. METHODS:A parallel arm randomized cont...

journal_title：BMC endocrine disorders

authors： Qasim R,Masih S,Yousafzai MT,Shah H,Manan A,Shah Y,Yaqoob M,Razzaq A,Khan A,Rohilla ARK

更新日期：2020-06-16 00:00:00